Simultaneous pharmacokinetic screening of a mixture of compounds in the dog using API LC/MS/MS analysis for increased throughput

Journal of Medicinal Chemistry

Volumn 40, Issue 6, 1997, Pages 827-829

  Berman, J ^a   Halm, K ^a   Adkison, K ^a   Shaffer, J ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 1A ADRENERGIC RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOG; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG MIXTURE; DRUG SCREENING; INTRADUODENAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; ORAL DRUG ADMINISTRATION;

ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; CHROMATOGRAPHY, LIQUID; DOGS; DRUG EVALUATION, PRECLINICAL; MASS SPECTROMETRY; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0031000066     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960702s     Document Type: Article

References (8)