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Volumn 5, Issue AUG, 2014, Pages

Genetic factors and manganese-induced neurotoxicity

Author keywords

Manganese; Manganism; Neurotoxicity; Parkinson's disease

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ALPHA SYNUCLEIN; AROMATIC LEVO AMINO ACID DECARBOXYLASE; CALCIUM CHANNEL; DJ 1 PROTEIN; DOPAMINE TRANSPORTER; FERROPORTIN; LEUCINE RICH REPEAT KINASE 2; MANGANESE; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 2; NUCLEAR RECEPTOR RELATED FACTOR 1; PARKIN; PINK1 PROTEIN; PROTEIN; PROTEIN ATP 13A2; PROTEIN ZIP 8; UBIQUITIN CARBOXY TERMINAL HYDROLASE L1; UNCLASSIFIED DRUG; VESICULAR MONOAMINE TRANSPORTER 2; ZINC TRANSPORTER;

EID: 84906253393     PISSN: None     EISSN: 16648021     Source Type: Journal    
DOI: 10.3389/fgene.2014.00265     Document Type: Short Survey
Times cited : (79)

References (123)
  • 1
    • 35548972027 scopus 로고    scopus 로고
    • DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase
    • doi: 10.1073/pnas.0703219104
    • Andres-Mateos, E., Perier, C., Zhang, L., Blanchard-Fillion, B., Greco, T. M., Thomas, B.,et al. (2007). DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase. Proc. Natl. Acad. Sci. U.S.A. 104, 14807-14812. doi: 10.1073/pnas.0703219104
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 14807-14812
    • Andres-Mateos, E.1    Perier, C.2    Zhang, L.3    Blanchard-Fillion, B.4    Greco, T.M.5    Thomas, B.6
  • 2
    • 80052710500 scopus 로고    scopus 로고
    • Visual symptoms in Parkinson's disease.
    • doi: 10.4061/2011/908306
    • Armstrong, R. A. (2011). Visual symptoms in Parkinson's disease. Parkinsons Dis. 2011:908306. doi: 10.4061/2011/908306
    • (2011) Parkinsons Dis. , vol.2011 , pp. 908306
    • Armstrong, R.A.1
  • 3
    • 0033911123 scopus 로고    scopus 로고
    • Manganese: brain transport and emerging research needs
    • doi: 10.1289/ehp.00108s3429
    • Aschner, M. (2000). Manganese: brain transport and emerging research needs. Environ. Health Perspect. 108(Suppl. 3), 429-432. doi: 10.1289/ehp.00108s3429
    • (2000) Environ. Health Perspect. , vol.108 , Issue.SUPPL. 3 , pp. 429-432
    • Aschner, M.1
  • 4
    • 0036628676 scopus 로고    scopus 로고
    • Open issues from the 15th International Conference on Manganese
    • doi: 10.1016/S0161-813X(01)00097-3
    • Aschner, M. (2002). Open issues from the 15th International Conference on Manganese. Neurotoxicology 23, 123-125. doi: 10.1016/S0161-813X(01)00097-3
    • (2002) Neurotoxicology , vol.23 , pp. 123-125
    • Aschner, M.1
  • 5
    • 0028366603 scopus 로고
    • Manganese (Mn) transport across the rat blood-brain barrier: saturable and transferrin-dependent transport mechanisms
    • doi: 10.1016/0361-9230(94)90204-6
    • Aschner, M., and Gannon, M. (1994). Manganese (Mn) transport across the rat blood-brain barrier: saturable and transferrin-dependent transport mechanisms. Brain Res. Bull. 33, 345-349. doi: 10.1016/0361-9230(94)90204-6
    • (1994) Brain Res. Bull. , vol.33 , pp. 345-349
    • Aschner, M.1    Gannon, M.2
  • 6
    • 0003815867 scopus 로고    scopus 로고
    • ATSDR. Atlanta, GA: U.S. Department of Health and Human Services, Public Service.
    • ATSDR. (2012). Toxicological Profile for Manganese. Atlanta, GA: U.S. Department of Health and Human Services, Public Service.
    • (2012) Toxicological Profile for Manganese.
  • 7
    • 70849094908 scopus 로고    scopus 로고
    • SMF-1, SMF-2, and SMF-3 DMT1 orthologues regulate and are regulated differentially by manganese levels in C. elegans
    • doi: 10.1371/journal.pone.0007792
    • Au, C., Benedetto, A., Anderson, J., Labrousse, A., Erikson, K., Ewbank, J. J.,et al. (2009). SMF-1, SMF-2, and SMF-3 DMT1 orthologues regulate and are regulated differentially by manganese levels in C. elegans . PLoS ONE 4:e7792. doi: 10.1371/journal.pone.0007792
    • (2009) PLoS ONE , vol.4
    • Au, C.1    Benedetto, A.2    Anderson, J.3    Labrousse, A.4    Erikson, K.5    Ewbank, J.J.6
  • 8
    • 0342470567 scopus 로고    scopus 로고
    • A selective group of dopaminergic neurons express Nurr1 in the adult mouse brain
    • doi: 10.1016/S0006-8993(99)02149-6
    • Bäckman, C., Perlmann, T., Wallén, Å., Hoffer, B. J., and Morales, M. (1999). A selective group of dopaminergic neurons express Nurr1 in the adult mouse brain. Brain Res. 851, 125-132. doi: 10.1016/S0006-8993(99)02149-6
    • (1999) Brain Res. , vol.851 , pp. 125-132
    • Bäckman, C.1    Perlmann, T.2    Wallén, Å.3    Hoffer, B.J.4    Morales, M.5
  • 9
    • 0024599449 scopus 로고
    • Higher retention of manganese in suckling than in adult rats is not due to maturational differences in manganese uptake by rat small intestine
    • doi: 10.1080/15287398909531263
    • Bell, J. G., Keen, C. L., and Lonnerdal, B. (1989). Higher retention of manganese in suckling than in adult rats is not due to maturational differences in manganese uptake by rat small intestine. J. Toxicol. Environ. Health 26, 387-398. doi: 10.1080/15287398909531263
    • (1989) J. Toxicol. Environ. Health , vol.26 , pp. 387-398
    • Bell, J.G.1    Keen, C.L.2    Lonnerdal, B.3
  • 10
    • 70350639468 scopus 로고    scopus 로고
    • Manganese-induced dopaminergic neurodegeneration: insights into mechanisms and genetics shared with Parkinson's disease
    • doi: 10.1021/cr800536y
    • Benedetto, A., Au, C., and Aschner, M. (2009). Manganese-induced dopaminergic neurodegeneration: insights into mechanisms and genetics shared with Parkinson's disease. Chem. Rev. 109, 4862-4884. doi: 10.1021/cr800536y
    • (2009) Chem. Rev. , vol.109 , pp. 4862-4884
    • Benedetto, A.1    Au, C.2    Aschner, M.3
  • 11
    • 77957363643 scopus 로고    scopus 로고
    • Extracellular dopamine potentiates mn-induced oxidative stress, lifespan reduction, and dopaminergic neurodegeneration in a BLI-3-dependent manner in Caenorhabditis elegans .
    • doi: 10.1371/journal.pgen.1001084
    • Benedetto, A., Au, C., Avila, D. S., Milatovic, D., and Aschner, M. (2010). Extracellular dopamine potentiates mn-induced oxidative stress, lifespan reduction, and dopaminergic neurodegeneration in a BLI-3-dependent manner in Caenorhabditis elegans . PLoS Genet. 6:e1001084. doi: 10.1371/journal.pgen.1001084
    • (2010) PLoS Genet. , vol.6
    • Benedetto, A.1    Au, C.2    Avila, D.S.3    Milatovic, D.4    Aschner, M.5
  • 12
    • 58549089901 scopus 로고    scopus 로고
    • α-synuclein and polyunsaturated fatty acids promote clathrin-mediated endocytosis and synaptic vesicle recycling
    • doi: 10.1111/j.1600-0854.2008.00853.x
    • Ben Gedalya, T., Loeb, V., Israeli, E., Altschuler, Y., Selkoe, D. J., and Sharon, R. (2009). α-synuclein and polyunsaturated fatty acids promote clathrin-mediated endocytosis and synaptic vesicle recycling. Traffic 10, 218-234. doi: 10.1111/j.1600-0854.2008.00853.x
    • (2009) Traffic , vol.10 , pp. 218-234
    • Ben Gedalya, T.1    Loeb, V.2    Israeli, E.3    Altschuler, Y.4    Selkoe, D.J.5    Sharon, R.6
  • 13
    • 84881221713 scopus 로고    scopus 로고
    • Parkinson disease protein DJ-1 binds metals and protects against metal-induced cytotoxicity
    • doi: 10.1074/jbc.M113.482091
    • Björkblom, B., Adilbayeva, A., Maple-Grødem, J., Piston, D., Ökvist, M., Xu, X. M.,et al. (2013). Parkinson disease protein DJ-1 binds metals and protects against metal-induced cytotoxicity. J. Biol. Chem. 288, 22809-22820. doi: 10.1074/jbc.M113.482091
    • (2013) J. Biol. Chem. , vol.288 , pp. 22809-22820
    • Björkblom, B.1    Adilbayeva, A.2    Maple-Grødem, J.3    Piston, D.4    Ökvist, M.5    Xu, X.M.6
  • 14
    • 0026688441 scopus 로고
    • The structure of human mitochondrial manganese superoxide dismutase reveals a novel tetrameric interface of two 4-helix bundles
    • doi: 10.1016/0092-8674(92)90270-M
    • Borgstahl, G. E., Parge, H. E., Hickey, M. J., Beyer, W. F. Jr., Hallewell, R. A., and Tainer, J. A. (1992). The structure of human mitochondrial manganese superoxide dismutase reveals a novel tetrameric interface of two 4-helix bundles. Cell 71, 107-118. doi: 10.1016/0092-8674(92)90270-M
    • (1992) Cell , vol.71 , pp. 107-118
    • Borgstahl, G.E.1    Parge, H.E.2    Hickey, M.J.3    Beyer Jr., W.F.4    Hallewell, R.A.5    Tainer, J.A.6
  • 15
    • 84896864748 scopus 로고    scopus 로고
    • The effects of pdr1, djr1.1 and pink1 loss in manganese-induced toxicity and the role of α-synuclein in C. elegans
    • doi: 10.1039/C3MT00325F
    • Bornhorst, J., Chakraborty, S., Meyer, S., Lohren, H., Brinkhaus, S. G., Knight, A. L.,et al. (2014). The effects of pdr1, djr1.1 and pink1 loss in manganese-induced toxicity and the role of α-synuclein in C. elegans . Metallomics 6, 476-490. doi: 10.1039/C3MT00325F
    • (2014) Metallomics , vol.6 , pp. 476-490
    • Bornhorst, J.1    Chakraborty, S.2    Meyer, S.3    Lohren, H.4    Brinkhaus, S.G.5    Knight, A.L.6
  • 16
    • 84864773169 scopus 로고    scopus 로고
    • Efflux function, tissue-specific expression and intracellular trafficking of the Zn transporter ZnT10 indicate roles in adult Zn homeostasis
    • doi: 10.1039/C2MT20088K
    • Bosomworth, H. J., Thornton, J. K., Coneyworth, L. J., Ford, D., and Valentine, R. A. (2012). Efflux function, tissue-specific expression and intracellular trafficking of the Zn transporter ZnT10 indicate roles in adult Zn homeostasis. Metallomics 4, 771-779. doi: 10.1039/C2MT20088K
    • (2012) Metallomics , vol.4 , pp. 771-779
    • Bosomworth, H.J.1    Thornton, J.K.2    Coneyworth, L.J.3    Ford, D.4    Valentine, R.A.5
  • 17
    • 0035892632 scopus 로고    scopus 로고
    • Distribution of divalent metal transporter 1 and metal transport protein 1 in the normal and Belgrade rat
    • doi: 10.1002/jnr.1256
    • Burdo, J. R., Menzies, S. L., Simpson, I. A., Garrick, L. M., Garrick, M. D., Dolan, K. G.,et al. (2001a). Distribution of divalent metal transporter 1 and metal transport protein 1 in the normal and Belgrade rat. J. Neurosci. Res. 66, 1198-1207. doi: 10.1002/jnr.1256
    • (2001) J. Neurosci. Res. , vol.66 , pp. 1198-1207
    • Burdo, J.R.1    Menzies, S.L.2    Simpson, I.A.3    Garrick, L.M.4    Garrick, M.D.5    Dolan, K.G.6
  • 18
    • 0035892632 scopus 로고    scopus 로고
    • Distribution of divalent metal transporter 1 and metal transport protein 1 in the normal and Belgrade rat
    • doi: 10.1002/jnr.1256
    • Burdo, J. R., Menzies, S. L., Simpson, I. A., Garrick, L. M., Garrick, M. D., Dolan, K. G.,et al. (2001b). Distribution of divalent metal transporter 1 and metal transport protein 1 in the normal and Belgrade rat. J. Neurosci. Res. 66, 1198-1207. doi: 10.1002/jnr.1256
    • (2001) J. Neurosci. Res. , vol.66 , pp. 1198-1207
    • Burdo, J.R.1    Menzies, S.L.2    Simpson, I.A.3    Garrick, L.M.4    Garrick, M.D.5    Dolan, K.G.6
  • 19
    • 0029565415 scopus 로고
    • Manganese toxicity, dopaminergic dysfunction and hepatic encephalopathy
    • doi: 10.1007/BF02109357
    • Butterworth, R. F., Spahr, L., Fontaine, S., and Layrargues, G. P. (1995). Manganese toxicity, dopaminergic dysfunction and hepatic encephalopathy. Metab. Brain Dis. 10, 259-267. doi: 10.1007/BF02109357
    • (1995) Metab. Brain Dis. , vol.10 , pp. 259-267
    • Butterworth, R.F.1    Spahr, L.2    Fontaine, S.3    Layrargues, G.P.4
  • 20
    • 33745589773 scopus 로고    scopus 로고
    • Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
    • doi: 10.1038/nature04779
    • Clark, I. E., Dodson, M. W., Jiang, C., Cao, J. H., Huh, J. R., Seol, J. H.,et al. (2006). Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin. Nature 441, 1162-1166. doi: 10.1038/nature04779
    • (2006) Nature , vol.441 , pp. 1162-1166
    • Clark, I.E.1    Dodson, M.W.2    Jiang, C.3    Cao, J.H.4    Huh, J.R.5    Seol, J.H.6
  • 21
    • 0018099185 scopus 로고
    • The excretion of trace metals in human sweat.
    • Cohn, J. R., and Emmett, E. A. (1978). The excretion of trace metals in human sweat. Ann. Clin. Lab. Sci. 8, 270-275.
    • (1978) Ann. Clin. Lab. Sci. , vol.8 , pp. 270-275
    • Cohn, J.R.1    Emmett, E.A.2
  • 22
    • 0002240298 scopus 로고
    • On the effects of black oxide manganese when inhaled into the lungs.
    • Couper, J. (1837). On the effects of black oxide manganese when inhaled into the lungs. Brit. Ann. Med. Pharm. Vital Stat. Gen. Sci. 1, 41-42.
    • (1837) Brit. Ann. Med. Pharm. Vital Stat. Gen. Sci. , vol.1 , pp. 41-42
    • Couper, J.1
  • 23
    • 84862789781 scopus 로고    scopus 로고
    • Basal ganglia intensity indices and diffusion weighted imaging in manganese-exposed welders
    • doi: 10.1136/oemed-2011-100119
    • Criswell, S. R., Perlmutter, J. S., Huang, J. L., Golchin, N., Flores, H. P., Hobson, A.,et al. (2012). Basal ganglia intensity indices and diffusion weighted imaging in manganese-exposed welders. Occup. Environ. Med. 69, 437-443. doi: 10.1136/oemed-2011-100119
    • (2012) Occup. Environ. Med. , vol.69 , pp. 437-443
    • Criswell, S.R.1    Perlmutter, J.S.2    Huang, J.L.3    Golchin, N.4    Flores, H.P.5    Hobson, A.6
  • 24
    • 0037234204 scopus 로고    scopus 로고
    • Manganese distribution across the blood-brain barrier. I. Evidence for carrier-mediated influx of managanese citrate as well as manganese and manganese transferrin
    • doi: 10.1016/S0161-813X(02)00089-X
    • Crossgrove, J. S., Allen, D. D., Bukaveckas, B. L., Rhineheimer, S. S., and Yokel, R. A. (2003). Manganese distribution across the blood-brain barrier. I. Evidence for carrier-mediated influx of managanese citrate as well as manganese and manganese transferrin. Neurotoxicology 24, 3-13. doi: 10.1016/S0161-813X(02)00089-X
    • (2003) Neurotoxicology , vol.24 , pp. 3-13
    • Crossgrove, J.S.1    Allen, D.D.2    Bukaveckas, B.L.3    Rhineheimer, S.S.4    Yokel, R.A.5
  • 25
    • 0027506643 scopus 로고
    • Manganese metabolism in rats: an improved methodology for assessing gut endogenous losses
    • doi: 10.3181/00379727-202-43518
    • Davis, C. D., Zech, L., and Greger, J. L. (1993). Manganese metabolism in rats: an improved methodology for assessing gut endogenous losses. Proc. Soc. Exp. Biol. Med. 202, 103-108. doi: 10.3181/00379727-202-43518
    • (1993) Proc. Soc. Exp. Biol. Med. , vol.202 , pp. 103-108
    • Davis, C.D.1    Zech, L.2    Greger, J.L.3
  • 26
    • 0014480825 scopus 로고
    • A comparison of the effects of different divalent cations on a number of mitochondrial reactions linked to ion translocation
    • doi: 10.1016/0003-9861(69)90033-2
    • Drahota, Z., Gazzotti, P., Carafoli, E., and Rossi, C. S. (1969). A comparison of the effects of different divalent cations on a number of mitochondrial reactions linked to ion translocation. Arch. Biochem. Biophys. 130, 267-273. doi: 10.1016/0003-9861(69)90033-2
    • (1969) Arch. Biochem. Biophys. , vol.130 , pp. 267-273
    • Drahota, Z.1    Gazzotti, P.2    Carafoli, E.3    Rossi, C.S.4
  • 27
    • 0036778081 scopus 로고    scopus 로고
    • Manganese causes differential regulation of glutamate transporter (GLAST) taurine transporter and metallothionein in cultured rat astrocytes
    • doi: 10.1016/S0161-813X(02)00012-8
    • Erikson, K., and Aschner, M. (2002). Manganese causes differential regulation of glutamate transporter (GLAST) taurine transporter and metallothionein in cultured rat astrocytes. Neurotoxicology 23, 595-602. doi: 10.1016/S0161-813X(02)00012-8
    • (2002) Neurotoxicology , vol.23 , pp. 595-602
    • Erikson, K.1    Aschner, M.2
  • 28
    • 0031753319 scopus 로고    scopus 로고
    • Manganese uptake and release by cultured human hepato-carcinoma (Hep-G2) cells
    • doi: 10.1007/BF02783328
    • Finley, J. W. (1998). Manganese uptake and release by cultured human hepato-carcinoma (Hep-G2) cells. Biol. Trace Elem. Res. 64, 101-118. doi: 10.1007/BF02783328
    • (1998) Biol. Trace Elem. Res. , vol.64 , pp. 101-118
    • Finley, J.W.1
  • 29
    • 0028134942 scopus 로고
    • Sex affects manganese absorption and retention by humans from a diet adequate in manganese.
    • Finley, J. W., Johnson, P. E., and Johnson, L. K. (1994). Sex affects manganese absorption and retention by humans from a diet adequate in manganese. Am. J. Clin. Nutr. 60, 949-955.
    • (1994) Am. J. Clin. Nutr. , vol.60 , pp. 949-955
    • Finley, J.W.1    Johnson, P.E.2    Johnson, L.K.3
  • 31
    • 0040452182 scopus 로고
    • Skeletal deformities in manganese-deficient rats
    • doi: 10.1002/ar.1091340105
    • Frost, G., Asling, C. W., and Nelson, M. M. (1959). Skeletal deformities in manganese-deficient rats. Anat. Rec. 134, 37-53. doi: 10.1002/ar.1091340105
    • (1959) Anat. Rec. , vol.134 , pp. 37-53
    • Frost, G.1    Asling, C.W.2    Nelson, M.M.3
  • 32
    • 79960183388 scopus 로고    scopus 로고
    • High sensitivity of RBL-2H3 cells to cadmium and manganese: an implication of the role of ZIP8
    • doi: 10.1039/c1mt00020a
    • Fujishiro, H., Doi, M., Enomoto, S., and Himeno, S. (2011). High sensitivity of RBL-2H3 cells to cadmium and manganese: an implication of the role of ZIP8. Metallomics 3, 710-718. doi: 10.1039/c1mt00020a
    • (2011) Metallomics , vol.3 , pp. 710-718
    • Fujishiro, H.1    Doi, M.2    Enomoto, S.3    Himeno, S.4
  • 33
    • 0037354265 scopus 로고    scopus 로고
    • DMT1: a mammalian transporter for multiple metals
    • doi: 10.1023/A:1020702213099
    • Garrick, M. D., Dolan, K. G., Horbinski, C., Ghio, A. J., Higgins, D., Porubcin, M.,et al. (2003). DMT1: a mammalian transporter for multiple metals. Biometals 16, 41-54. doi: 10.1023/A:1020702213099
    • (2003) Biometals , vol.16 , pp. 41-54
    • Garrick, M.D.1    Dolan, K.G.2    Horbinski, C.3    Ghio, A.J.4    Higgins, D.5    Porubcin, M.6
  • 34
    • 0025342844 scopus 로고
    • Manganese and calcium efflux kinetics in brain mitochondria. Relevance to manganese toxicity.
    • Gavin, C. E., Gunter, K. K., and Gunter, T. E. (1990). Manganese and calcium efflux kinetics in brain mitochondria. Relevance to manganese toxicity. Biochem. J. 266, 329-334.
    • (1990) Biochem. J. , vol.266 , pp. 329-334
    • Gavin, C.E.1    Gunter, K.K.2    Gunter, T.E.3
  • 35
    • 0033002854 scopus 로고    scopus 로고
    • Manganese and calcium transport in mitochondria: implications for manganese toxicity.
    • Gavin, C. E., Gunter, K. K., and Gunter, T. E. (1999). Manganese and calcium transport in mitochondria: implications for manganese toxicity. Neurotoxicology 20, 445-453.
    • (1999) Neurotoxicology , vol.20 , pp. 445-453
    • Gavin, C.E.1    Gunter, K.K.2    Gunter, T.E.3
  • 36
    • 38349160161 scopus 로고    scopus 로고
    • The Parkinson's disease protein α-synuclein disrupts cellular Rab homeostasis
    • doi: 10.1073/pnas.0710685105
    • Gitler, A. D., Bevis, B. J., Shorter, J., Strathearn, K. E., Hamamichi, S., Su, L. J.,et al. (2008). The Parkinson's disease protein α-synuclein disrupts cellular Rab homeostasis. Proc. Natl. Acad. Sci. U.S.A. 105, 145-150. doi: 10.1073/pnas.0710685105
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 145-150
    • Gitler, A.D.1    Bevis, B.J.2    Shorter, J.3    Strathearn, K.E.4    Hamamichi, S.5    Su, L.J.6
  • 37
    • 61349147706 scopus 로고    scopus 로고
    • α-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity
    • doi: 10.1038/ng.300
    • Gitler, A. D., Chesi, A., Geddie, M. L., Strathearn, K. E., Hamamichi, S., Hill, K. J.,et al. (2009). α-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity. Nat. Genet. 41, 308-315. doi: 10.1038/ng.300
    • (2009) Nat. Genet. , vol.41 , pp. 308-315
    • Gitler, A.D.1    Chesi, A.2    Geddie, M.L.3    Strathearn, K.E.4    Hamamichi, S.5    Hill, K.J.6
  • 38
    • 33747199933 scopus 로고    scopus 로고
    • Ubiquitin hydrolase Uch-L1 rescues Β-amyloid-induced decreases in synaptic function and contextual memory
    • doi: 10.1016/j.cell.2006.06.046
    • Gong, B., Cao, Z., Zheng, P., Vitolo, O. V., Liu, S., Staniszewski, A.,et al. (2006). Ubiquitin hydrolase Uch-L1 rescues Β-amyloid-induced decreases in synaptic function and contextual memory. Cell 126, 775-788. doi: 10.1016/j.cell.2006.06.046
    • (2006) Cell , vol.126 , pp. 775-788
    • Gong, B.1    Cao, Z.2    Zheng, P.3    Vitolo, O.V.4    Liu, S.5    Staniszewski, A.6
  • 39
    • 0021364248 scopus 로고
    • Manganese-dependent cell-substratum adhesion.
    • Grinnell, F. (1984). Manganese-dependent cell-substratum adhesion. J. Cell Sci. 65, 61-72.
    • (1984) J. Cell Sci. , vol.65 , pp. 61-72
    • Grinnell, F.1
  • 40
    • 0016608437 scopus 로고
    • Quantitative magnetic resonance studies of manganese uptake by mitochondria
    • doi: 10.1016/S0006-3495(75)85822-X
    • Gunter, R. E., Puskin, J. S., and Russell, P. R. (1975). Quantitative magnetic resonance studies of manganese uptake by mitochondria. Biophys. J. 15, 319-333. doi: 10.1016/S0006-3495(75)85822-X
    • (1975) Biophys. J. , vol.15 , pp. 319-333
    • Gunter, R.E.1    Puskin, J.S.2    Russell, P.R.3
  • 41
    • 0015351073 scopus 로고
    • Manganous ion as a spin label in studies of mitochondrial uptake of manganese
    • doi: 10.1016/S0006-3495(72)86108-3
    • Gunter, T. E., and Puskin, J. S. (1972). Manganous ion as a spin label in studies of mitochondrial uptake of manganese. Biophys. J. 12, 625-635. doi: 10.1016/S0006-3495(72)86108-3
    • (1972) Biophys. J. , vol.12 , pp. 625-635
    • Gunter, T.E.1    Puskin, J.S.2
  • 42
    • 48749095219 scopus 로고    scopus 로고
    • Expression of the LRRK2 gene in the midbrain dopaminergic neurons of the substantia nigra
    • doi: 10.1016/j.neulet.2008.06.086
    • Han, B.-S., Iacovitti, L., Katano, T., Hattori, N., Seol, W., and Kim, K.-S. (2008). Expression of the LRRK2 gene in the midbrain dopaminergic neurons of the substantia nigra. Neurosci. Lett. 442, 190-194. doi: 10.1016/j.neulet.2008.06.086
    • (2008) Neurosci. Lett. , vol.442 , pp. 190-194
    • Han, B.-S.1    Iacovitti, L.2    Katano, T.3    Hattori, N.4    Seol, W.5    Kim, K.-S.6
  • 43
    • 33745249951 scopus 로고    scopus 로고
    • ZIP8, member of the solute-carrier-39 (SLC39) metal-transporter family: characterization of transporter properties
    • doi: 10.1124/mol.106.024521
    • He, L., Girijashanker, K., Dalton, T. P., Reed, J., Li, H., Soleimani, M.,et al. (2006). ZIP8, member of the solute-carrier-39 (SLC39) metal-transporter family: characterization of transporter properties. Mol. Pharmacol. 70, 171-180. doi: 10.1124/mol.106.024521
    • (2006) Mol. Pharmacol. , vol.70 , pp. 171-180
    • He, L.1    Girijashanker, K.2    Dalton, T.P.3    Reed, J.4    Li, H.5    Soleimani, M.6
  • 44
    • 79961207947 scopus 로고    scopus 로고
    • DMT1 polymorphism and risk of Parkinson's disease
    • doi: 10.1016/j.neulet.2011.07.001
    • He, Q., Du, T., Yu, X., Xie, A., Song, N., Kang, Q.,et al. (2011). DMT1 polymorphism and risk of Parkinson's disease. Neurosci. Lett. 501, 128-131. doi: 10.1016/j.neulet.2011.07.001
    • (2011) Neurosci. Lett. , vol.501 , pp. 128-131
    • He, Q.1    Du, T.2    Yu, X.3    Xie, A.4    Song, N.5    Kang, Q.6
  • 45
    • 0043065330 scopus 로고    scopus 로고
    • Nurr1 regulates dopamine synthesis and storage in MN9D dopamine cells
    • doi: 10.1016/S0014-4827(03)00216-7
    • Hermanson, E., Joseph, B., Castro, D., Lindqvist, E., Aarnisalo, P., Wallén, Å.,et al. (2003). Nurr1 regulates dopamine synthesis and storage in MN9D dopamine cells. Exp. Cell Res. 288, 324-334. doi: 10.1016/S0014-4827(03)00216-7
    • (2003) Exp. Cell Res. , vol.288 , pp. 324-334
    • Hermanson, E.1    Joseph, B.2    Castro, D.3    Lindqvist, E.4    Aarnisalo, P.5    Wallén, Å.6
  • 46
    • 69749121831 scopus 로고    scopus 로고
    • The role of zinc transporters in cadmium and manganese transport in mammalian cells
    • doi: 10.1016/j.biochi.2009.04.002
    • Himeno, S., Yanagiya, T., and Fujishiro, H. (2009). The role of zinc transporters in cadmium and manganese transport in mammalian cells. Biochimie 91, 1218-1222. doi: 10.1016/j.biochi.2009.04.002
    • (2009) Biochimie , vol.91 , pp. 1218-1222
    • Himeno, S.1    Yanagiya, T.2    Fujishiro, H.3
  • 47
    • 0033103726 scopus 로고    scopus 로고
    • Identification and characterization of a novel protein that regulates RNA-protein interaction
    • doi: 10.1002/(SICI)1097-4644(19990301)72:3<435::AID-JCB12>3.0.CO;2-H
    • Hod, Y., Pentyala, S. N., Whyard, T. C., and El-Maghrabi, M. R. (1999). Identification and characterization of a novel protein that regulates RNA-protein interaction. J. Cell. Biochem. 72, 435-444. doi: 10.1002/(SICI)1097-4644(19990301)72:3<435::AID-JCB12>3.0.CO;2-H
    • (1999) J. Cell. Biochem. , vol.72 , pp. 435-444
    • Hod, Y.1    Pentyala, S.N.2    Whyard, T.C.3    El-Maghrabi, M.R.4
  • 48
    • 0033890821 scopus 로고    scopus 로고
    • α-synuclein promotes mitochondrial deficit and oxidative stress
    • doi: 10.1016/S0002-9440(10)64553-1
    • Hsu, L. J., Sagara, Y., Arroyo, A., Rockenstein, E., Sisk, A., Mallory, M.,et al. (2000). α-synuclein promotes mitochondrial deficit and oxidative stress. Am. J. Pathol. 157, 401-410. doi: 10.1016/S0002-9440(10)64553-1
    • (2000) Am. J. Pathol. , vol.157 , pp. 401-410
    • Hsu, L.J.1    Sagara, Y.2    Arroyo, A.3    Rockenstein, E.4    Sisk, A.5    Mallory, M.6
  • 49
    • 0031918123 scopus 로고    scopus 로고
    • Long-term progression in chronic manganism: ten years of follow-up
    • doi: 10.1212/WNL.50.3.698
    • Huang, C. C., Chu, N. S., Lu, C. S., Chen, R. S., and Calne, D. B. (1998). Long-term progression in chronic manganism: ten years of follow-up. Neurology 50, 698-700. doi: 10.1212/WNL.50.3.698
    • (1998) Neurology , vol.50 , pp. 698-700
    • Huang, C.C.1    Chu, N.S.2    Lu, C.S.3    Chen, R.S.4    Calne, D.B.5
  • 50
    • 33947217471 scopus 로고    scopus 로고
    • The natural history of neurological manganism over 18 years
    • doi: 10.1016/j.parkreldis.2006.09.002
    • Huang, C. C., Chu, N. S., Lu, C. S., Chen, R. S., Schulzer, M., and Calne, D. B. (2007). The natural history of neurological manganism over 18 years. Parkinsonism Relat. Disord. 13, 143-145. doi: 10.1016/j.parkreldis.2006.09.002
    • (2007) Parkinsonism Relat. Disord. , vol.13 , pp. 143-145
    • Huang, C.C.1    Chu, N.S.2    Lu, C.S.3    Chen, R.S.4    Schulzer, M.5    Calne, D.B.6
  • 51
    • 0024455148 scopus 로고
    • Chronic manganese intoxication
    • doi: 10.1001/archneur.1989.00520460090018
    • Huang, C. C., Chu, N. S., Lu, C. S., Wang, J. D., Tsai, J. L., Tzeng, J. L.,et al. (1989). Chronic manganese intoxication. Arch. Neurol. 46, 1104-1106. doi: 10.1001/archneur.1989.00520460090018
    • (1989) Arch. Neurol. , vol.46 , pp. 1104-1106
    • Huang, C.C.1    Chu, N.S.2    Lu, C.S.3    Wang, J.D.4    Tsai, J.L.5    Tzeng, J.L.6
  • 52
    • 0027249375 scopus 로고
    • Progression after chronic manganese exposure
    • doi: 10.1212/WNL.43.8.1479
    • Huang, C. C., Lu, C. S., Chu, N. S., Hochberg, F., Lilienfeld, D., Olanow, W.,et al. (1993). Progression after chronic manganese exposure. Neurology 43, 1479-1483. doi: 10.1212/WNL.43.8.1479
    • (1993) Neurology , vol.43 , pp. 1479-1483
    • Huang, C.C.1    Lu, C.S.2    Chu, N.S.3    Hochberg, F.4    Lilienfeld, D.5    Olanow, W.6
  • 53
    • 4644365735 scopus 로고    scopus 로고
    • Distribution of divalent metal transporter-1 in the monkey basal ganglia
    • doi: 10.1016/j.neuroscience.2004.06.055
    • Huang, E., Ong, W. Y., and Connor, J. R. (2004). Distribution of divalent metal transporter-1 in the monkey basal ganglia. Neuroscience 128, 487-496. doi: 10.1016/j.neuroscience.2004.06.055
    • (2004) Neuroscience , vol.128 , pp. 487-496
    • Huang, E.1    Ong, W.Y.2    Connor, J.R.3
  • 54
    • 0034660635 scopus 로고    scopus 로고
    • Manganese deposition in the globus pallidus in patients with biliary atresia
    • doi: 10.1097/00007890-200006150-00021
    • Ikeda, S., Yamaguchi, Y., Sera, Y., Ohshiro, H., Uchino, S., Yamashita, Y.,et al. (2000). Manganese deposition in the globus pallidus in patients with biliary atresia. Transplantation 69, 2339-2343. doi: 10.1097/00007890-200006150-00021
    • (2000) Transplantation , vol.69 , pp. 2339-2343
    • Ikeda, S.1    Yamaguchi, Y.2    Sera, Y.3    Ohshiro, H.4    Uchino, S.5    Yamashita, Y.6
  • 55
    • 0032997529 scopus 로고    scopus 로고
    • Central nervous system toxicity of manganese. II. Cocaine or reserpine inhibit manganese concentration in the rat brain.
    • Ingersoll, R. T., Montgomery, E. B., and Aposhian, H. V. (1999). Central nervous system toxicity of manganese. II. Cocaine or reserpine inhibit manganese concentration in the rat brain. Neurotoxicology 20, 467-476.
    • (1999) Neurotoxicology , vol.20 , pp. 467-476
    • Ingersoll, R.T.1    Montgomery, E.B.2    Aposhian, H.V.3
  • 56
    • 0025727470 scopus 로고
    • Portal-systemic encephalopathy: presence of basal ganglia lesions with high signal intensity on MR images
    • doi: 10.1148/radiology.179.2.2014310
    • Inoue, E., Hori, S., Narumi, Y., Fujita, M., Kuriyama, K., Kadota, T.,et al. (1991). Portal-systemic encephalopathy: presence of basal ganglia lesions with high signal intensity on MR images. Radiology 179, 551-555. doi: 10.1148/radiology.179.2.2014310
    • (1991) Radiology , vol.179 , pp. 551-555
    • Inoue, E.1    Hori, S.2    Narumi, Y.3    Fujita, M.4    Kuriyama, K.5    Kadota, T.6
  • 57
    • 27844547616 scopus 로고    scopus 로고
    • The role of Nurr1 in the development of dopaminergic neurons and Parkinson's disease
    • doi: 10.1016/j.pneurobio.2005.09.001
    • Jankovic, J., Chen, S., and Le, W. D. (2005). The role of Nurr1 in the development of dopaminergic neurons and Parkinson's disease. Prog. Neurobiol. 77, 128-138. doi: 10.1016/j.pneurobio.2005.09.001
    • (2005) Prog. Neurobiol. , vol.77 , pp. 128-138
    • Jankovic, J.1    Chen, S.2    Le, W.D.3
  • 58
    • 84855972240 scopus 로고    scopus 로고
    • Neuropathology of sporadic Parkinson's disease: evaluation and changes of concepts
    • doi: 10.1002/mds.23795
    • Jellinger, K. A. (2012). Neuropathology of sporadic Parkinson's disease: evaluation and changes of concepts. Mov. Disord. 27, 8-30. doi: 10.1002/mds.23795
    • (2012) Mov. Disord. , vol.27 , pp. 8-30
    • Jellinger, K.A.1
  • 59
    • 47549095244 scopus 로고    scopus 로고
    • Brain manganese deposition depicted by magnetic resonance imaging in a welder
    • doi: 10.1001/archneur.65.7.983
    • Jorge da Silva, C., José Da Rocha, A., Mendes, M., Braga, A., and Jeronymo, S. (2008). Brain manganese deposition depicted by magnetic resonance imaging in a welder. Arch. Neurol. 65, 983-983. doi: 10.1001/archneur.65.7.983
    • (2008) Arch. Neurol. , vol.65 , pp. 983-983
    • Jorge da Silva, C.1    José Da Rocha, A.2    Mendes, M.3    Braga, A.4    Jeronymo, S.5
  • 60
    • 0022651524 scopus 로고
    • The effect of age on manganese uptake and retention from milk and infant formulas in rats.
    • Keen, C. L., Bell, J. G., and Lonnerdal, B. (1986). The effect of age on manganese uptake and retention from milk and infant formulas in rats. J. Nutr. 116, 395-402.
    • (1986) J. Nutr. , vol.116 , pp. 395-402
    • Keen, C.L.1    Bell, J.G.2    Lonnerdal, B.3
  • 61
    • 1542346257 scopus 로고    scopus 로고
    • Effect of levodopa treatment for parkinsonism in welders: a double-blind study
    • doi: 10.1212/01.WNL.0000113726.34734.15
    • Koller, W. C., Lyons, K. E., and Truly, W. (2004). Effect of levodopa treatment for parkinsonism in welders: a double-blind study. Neurology 62, 730-733. doi: 10.1212/01.WNL.0000113726.34734.15
    • (2004) Neurology , vol.62 , pp. 730-733
    • Koller, W.C.1    Lyons, K.E.2    Truly, W.3
  • 62
    • 0026459594 scopus 로고
    • Pallidal hyperintensity on magnetic resonance imaging in cirrhotic patients: clinical correlations
    • doi: 10.1002/hep.1840160613
    • Kulisevsky, J., Pujol, J., Balanzo, J., Junque, C., Deus, J., Capdevilla, A.,et al. (1992). Pallidal hyperintensity on magnetic resonance imaging in cirrhotic patients: clinical correlations. Hepatology 16, 1382-1388. doi: 10.1002/hep.1840160613
    • (1992) Hepatology , vol.16 , pp. 1382-1388
    • Kulisevsky, J.1    Pujol, J.2    Balanzo, J.3    Junque, C.4    Deus, J.5    Capdevilla, A.6
  • 63
    • 33644849650 scopus 로고    scopus 로고
    • Familial Parkinson mutant α-synuclein causes dopamine neuron dysfunction in transgenic Caenorhabditis elegans
    • doi: 10.1074/jbc.M504860200
    • Kuwahara, T., Koyama, A., Gengyo-Ando, K., Masuda, M., Kowa, H., Tsunoda, M.,et al. (2006). Familial Parkinson mutant α-synuclein causes dopamine neuron dysfunction in transgenic Caenorhabditis elegans . J. Biol. Chem. 281, 334-340. doi: 10.1074/jbc.M504860200
    • (2006) J. Biol. Chem. , vol.281 , pp. 334-340
    • Kuwahara, T.1    Koyama, A.2    Gengyo-Ando, K.3    Masuda, M.4    Kowa, H.5    Tsunoda, M.6
  • 64
    • 33747152560 scopus 로고    scopus 로고
    • Improving synaptic function in a mouse model of AD
    • doi: 10.1016/j.cell.2006.08.011
    • Lansbury, P. T. Jr. (2006). Improving synaptic function in a mouse model of AD. Cell 126, 655-657. doi: 10.1016/j.cell.2006.08.011
    • (2006) Cell , vol.126 , pp. 655-657
    • Lansbury, P.T.Jr.1
  • 65
    • 0037131567 scopus 로고    scopus 로고
    • The UCH-L1 gene encodes two opposing enzymatic activities that affect α-synuclein degradation and Parkinson's disease susceptibility
    • doi: 10.1016/S0092-8674(02)01012-7
    • Liu, Y., Fallon, L., Lashuel, H. A., Liu, Z., and Lansbury, P. T. Jr. (2002). The UCH-L1 gene encodes two opposing enzymatic activities that affect α-synuclein degradation and Parkinson's disease susceptibility. Cell 111, 209-218. doi: 10.1016/S0092-8674(02)01012-7
    • (2002) Cell , vol.111 , pp. 209-218
    • Liu, Y.1    Fallon, L.2    Lashuel, H.A.3    Liu, Z.4    Lansbury, P.T.Jr.5
  • 66
    • 0034760860 scopus 로고    scopus 로고
    • Inhibition of the rat blood-brain barrier choline transporter by manganese chloride
    • doi: 10.1046/j.1471-4159.2001.00589.x
    • Lockman, P. R., Roder, K. E., and Allen, D. D. (2001). Inhibition of the rat blood-brain barrier choline transporter by manganese chloride. J. Neurochem. 79, 588-594. doi: 10.1046/j.1471-4159.2001.00589.x
    • (2001) J. Neurochem. , vol.79 , pp. 588-594
    • Lockman, P.R.1    Roder, K.E.2    Allen, D.D.3
  • 67
    • 0030883645 scopus 로고    scopus 로고
    • Manganese transport through human erythrocyte membranes. An EPR study
    • doi: 10.1016/S0005-2736(97)00039-4
    • Lucaciu, C. M., Dragu, C., Copaescu, L., and Morariu, V. V. (1997). Manganese transport through human erythrocyte membranes. An EPR study. Biochim. Biophys. Acta 1328, 90-98. doi: 10.1016/S0005-2736(97)00039-4
    • (1997) Biochim. Biophys. Acta , vol.1328 , pp. 90-98
    • Lucaciu, C.M.1    Dragu, C.2    Copaescu, L.3    Morariu, V.V.4
  • 69
    • 35649023123 scopus 로고    scopus 로고
    • High prevalence of Parkinsonian disorders associated to manganese exposure in the vicinities of ferroalloy industries
    • doi: 10.1002/ajim.20494
    • Lucchini, R. G., Albini, E., Benedetti, L., Borghesi, S., Coccaglio, R., Malara, E. C.,et al. (2007). High prevalence of Parkinsonian disorders associated to manganese exposure in the vicinities of ferroalloy industries. Am. J. Ind. Med. 50, 788-800. doi: 10.1002/ajim.20494
    • (2007) Am. J. Ind. Med. , vol.50 , pp. 788-800
    • Lucchini, R.G.1    Albini, E.2    Benedetti, L.3    Borghesi, S.4    Coccaglio, R.5    Malara, E.C.6
  • 70
    • 84855719617 scopus 로고    scopus 로고
    • The iron transporter ferroportin can also function as a manganese exporter
    • doi: 10.1016/j.bbamem.2011.12.002
    • Madejczyk, M. S., and Ballatori, N. (2012). The iron transporter ferroportin can also function as a manganese exporter. Biochim. Biophys. Acta 1818, 651-657. doi: 10.1016/j.bbamem.2011.12.002
    • (2012) Biochim. Biophys. Acta , vol.1818 , pp. 651-657
    • Madejczyk, M.S.1    Ballatori, N.2
  • 71
    • 0030058089 scopus 로고    scopus 로고
    • Biliary manganese excretion in conscious rats is affected by acute and chronic manganese intake but not by dietary fat.
    • Malecki, E. A., Radzanowski, G. M., Radzanowski, T. J., Gallaher, D. D., and Greger, J. L. (1996). Biliary manganese excretion in conscious rats is affected by acute and chronic manganese intake but not by dietary fat. J. Nutr. 126, 489-498.
    • (1996) J. Nutr. , vol.126 , pp. 489-498
    • Malecki, E.A.1    Radzanowski, G.M.2    Radzanowski, T.J.3    Gallaher, D.D.4    Greger, J.L.5
  • 72
    • 0034681471 scopus 로고    scopus 로고
    • Dopaminergic loss and inclusion body formation in α-synuclein mice: implications for neurodegenerative disorders
    • doi: 10.1126/science.287.5456.1265
    • Masliah, E., Rockenstein, E., Veinbergs, I., Mallory, M., Hashimoto, M., Takeda, A.,et al. (2000). Dopaminergic loss and inclusion body formation in α-synuclein mice: implications for neurodegenerative disorders. Science 287, 1265-1269. doi: 10.1126/science.287.5456.1265
    • (2000) Science , vol.287 , pp. 1265-1269
    • Masliah, E.1    Rockenstein, E.2    Veinbergs, I.3    Mallory, M.4    Hashimoto, M.5    Takeda, A.6
  • 73
    • 0027193666 scopus 로고
    • Membrane interaction of calcium channel antagonists modulated by cholesterol. Implications for drug activity
    • doi: 10.1016/0006-2952(93)90186-Z
    • Mason, R. P. (1993). Membrane interaction of calcium channel antagonists modulated by cholesterol. Implications for drug activity. Biochem. Pharmacol. 45, 2173-2183. doi: 10.1016/0006-2952(93)90186-Z
    • (1993) Biochem. Pharmacol. , vol.45 , pp. 2173-2183
    • Mason, R.P.1
  • 74
    • 0016909223 scopus 로고
    • Iron- and manganese-containing superoxide dismutases: structure, distribution, and evolutionary relationships
    • doi: 10.1007/978-1-4684-3270-1_45
    • McCord, J. M. (1976). Iron- and manganese-containing superoxide dismutases: structure, distribution, and evolutionary relationships. Adv. Exp. Med. Biol. 74, 540-550. doi: 10.1007/978-1-4684-3270-1_45
    • (1976) Adv. Exp. Med. Biol. , vol.74 , pp. 540-550
    • McCord, J.M.1
  • 75
    • 0014051573 scopus 로고
    • Chronic manganese poisoning. Clinical picture and manganese turnover
    • doi: 10.1212/WNL.17.2.128
    • Mena, I., Marin, O., Fuenzalida, S., and Cotzias, G. C. (1967). Chronic manganese poisoning. Clinical picture and manganese turnover. Neurology 17, 128-136. doi: 10.1212/WNL.17.2.128
    • (1967) Neurology , vol.17 , pp. 128-136
    • Mena, I.1    Marin, O.2    Fuenzalida, S.3    Cotzias, G.C.4
  • 76
    • 34249845272 scopus 로고    scopus 로고
    • Reversible monoubiquitination regulates the Parkinson disease-associated ubiquitin hydrolase UCH-L1
    • doi: 10.1074/jbc.M611153200
    • Meray, R. K., and Lansbury, P. T. (2007). Reversible monoubiquitination regulates the Parkinson disease-associated ubiquitin hydrolase UCH-L1. J. Biol. Chem. 282, 10567-10575. doi: 10.1074/jbc.M611153200
    • (2007) J. Biol. Chem. , vol.282 , pp. 10567-10575
    • Meray, R.K.1    Lansbury, P.T.2
  • 77
    • 0035692636 scopus 로고    scopus 로고
    • DJ-1 is an indicator for endogenous reactive oxygen species elicited by endotoxin
    • doi: 10.1080/10715760100301381
    • Mitsumoto, A., and Nakagawa, Y. (2001). DJ-1 is an indicator for endogenous reactive oxygen species elicited by endotoxin. Free Radic. Res. 35, 885-893. doi: 10.1080/10715760100301381
    • (2001) Free Radic. Res. , vol.35 , pp. 885-893
    • Mitsumoto, A.1    Nakagawa, Y.2
  • 78
    • 0034906096 scopus 로고    scopus 로고
    • Oxidized forms of peroxiredoxins and DJ-1 on two-dimensional gels increased in response to sublethal levels of paraquat
    • doi: 10.1080/10715760100300831
    • Mitsumoto, A., Nakagawa, Y., Takeuchi, A., Okawa, K., Iwamatsu, A., and Takanezawa, Y. (2001). Oxidized forms of peroxiredoxins and DJ-1 on two-dimensional gels increased in response to sublethal levels of paraquat. Free Radic. Res. 35, 301-310. doi: 10.1080/10715760100300831
    • (2001) Free Radic. Res. , vol.35 , pp. 301-310
    • Mitsumoto, A.1    Nakagawa, Y.2    Takeuchi, A.3    Okawa, K.4    Iwamatsu, A.5    Takanezawa, Y.6
  • 79
    • 0026689961 scopus 로고
    • Uptake and distribution of iron and transferrin in the adult rat brain
    • doi: 10.1111/j.1471-4159.1992.tb08904.x
    • Morris, C. M., Keith, A. B., Edwardson, J. A., and Pullen, R. G. (1992). Uptake and distribution of iron and transferrin in the adult rat brain. J. Neurochem. 59, 300-306. doi: 10.1111/j.1471-4159.1992.tb08904.x
    • (1992) J. Neurochem. , vol.59 , pp. 300-306
    • Morris, C.M.1    Keith, A.B.2    Edwardson, J.A.3    Pullen, R.G.4
  • 81
    • 0033515471 scopus 로고    scopus 로고
    • Both familial Parkinson's disease mutations accelerate α-synuclein aggregation
    • doi: 10.1074/jbc.274.14.9843
    • Narhi, L., Wood, S. J., Steavenson, S., Jiang, Y., Wu, G. M., Anafi, D.,et al. (1999). Both familial Parkinson's disease mutations accelerate α-synuclein aggregation. J. Biol. Chem. 274, 9843-9846. doi: 10.1074/jbc.274.14.9843
    • (1999) J. Biol. Chem. , vol.274 , pp. 9843-9846
    • Narhi, L.1    Wood, S.J.2    Steavenson, S.3    Jiang, Y.4    Wu, G.M.5    Anafi, D.6
  • 82
    • 0024817437 scopus 로고
    • Visualizing manganese in the primate basal ganglia with magnetic resonance imaging
    • doi: 10.1016/0014-4886(89)90157-X
    • Newland, M. C., Ceckler, T. L., Kordower, J. H., and Weiss, B. (1989). Visualizing manganese in the primate basal ganglia with magnetic resonance imaging. Exp. Neurol. 106, 251-258. doi: 10.1016/0014-4886(89)90157-X
    • (1989) Exp. Neurol. , vol.106 , pp. 251-258
    • Newland, M.C.1    Ceckler, T.L.2    Kordower, J.H.3    Weiss, B.4
  • 83
    • 19044361911 scopus 로고    scopus 로고
    • An essay on the shaking palsy. 1817
    • doi: 10.1176/appi.neuropsych.14.2.223, discussion 222
    • Parkinson, J. (2002). An essay on the shaking palsy. 1817. J. Neuropsychiatry Clin. Neurosci. 14, 223-236; discussion 222. doi: 10.1176/appi.neuropsych.14.2.223
    • (2002) J. Neuropsychiatry Clin. Neurosci. , vol.14 , pp. 223-236
    • Parkinson, J.1
  • 84
    • 0037137702 scopus 로고    scopus 로고
    • Parkin protects against the toxicity associated with mutant α-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons
    • doi: 10.1016/S0896-6273(02)01125-X
    • Petrucelli, L., O'arrell, C., Lockhart, P. J., Baptista, M., Kehoe, K., Vink, L.,et al. (2002). Parkin protects against the toxicity associated with mutant α-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons. Neuron 36, 1007-1019. doi: 10.1016/S0896-6273(02)01125-X
    • (2002) Neuron , vol.36 , pp. 1007-1019
    • Petrucelli, L.1    O'arrell, C.2    Lockhart, P.J.3    Baptista, M.4    Kehoe, K.5    Vink, L.6
  • 85
    • 0027507044 scopus 로고
    • Hyperintense globus pallidus on T1-weighted MRI in cirrhotic patients is associated with severity of liver failure
    • doi: 10.1212/WNL.43.1_Part_1.65
    • Pujol, A., Pujol, J., Graus, F., Rimola, A., Peri, J., Mercader, J. M.,et al. (1993). Hyperintense globus pallidus on T1-weighted MRI in cirrhotic patients is associated with severity of liver failure. Neurology 43, 65-69. doi: 10.1212/WNL.43.1_Part_1.65
    • (1993) Neurology , vol.43 , pp. 65-69
    • Pujol, A.1    Pujol, J.2    Graus, F.3    Rimola, A.4    Peri, J.5    Mercader, J.M.6
  • 86
    • 84858074257 scopus 로고    scopus 로고
    • Mutations in SLC30A10 cause parkinsonism and dystonia with hypermanganesemia, polycythemia, and chronic liver disease
    • doi: 10.1016/j.ajhg.2012.01.017
    • Quadri, M., Federico, A., Zhao, T., Breedveld, G. J., Battisti, C., Delnooz, C.,et al. (2012). Mutations in SLC30A10 cause parkinsonism and dystonia with hypermanganesemia, polycythemia, and chronic liver disease. Am. J. Hum. Genet. 90, 467-477. doi: 10.1016/j.ajhg.2012.01.017
    • (2012) Am. J. Hum. Genet. , vol.90 , pp. 467-477
    • Quadri, M.1    Federico, A.2    Zhao, T.3    Breedveld, G.J.4    Battisti, C.5    Delnooz, C.6
  • 87
    • 84921279854 scopus 로고    scopus 로고
    • Manganism in the 21st century: the Hanninen lecture.
    • doi: 10.1016/j.neuro.2013.09.007 [Epub ahead of print].
    • Racette, B. A. (2013). Manganism in the 21st century: the Hanninen lecture. Neurotoxicology doi: 10.1016/j.neuro.2013.09.007 [Epub ahead of print].
    • (2013) Neurotoxicology
    • Racette, B.A.1
  • 88
    • 84867232624 scopus 로고    scopus 로고
    • Increased risk of parkinsonism associated with welding exposure
    • doi: 10.1016/j.neuro.2012.08.011
    • Racette, B. A., Criswell, S. R., Lundin, J. I., Hobson, A., Seixas, N., Kotzbauer, P. T.,et al. (2012). Increased risk of parkinsonism associated with welding exposure. Neurotoxicology 33, 1356-1361. doi: 10.1016/j.neuro.2012.08.011
    • (2012) Neurotoxicology , vol.33 , pp. 1356-1361
    • Racette, B.A.1    Criswell, S.R.2    Lundin, J.I.3    Hobson, A.4    Seixas, N.5    Kotzbauer, P.T.6
  • 89
    • 0035830444 scopus 로고    scopus 로고
    • Welding-related parkinsonism: clinical features, treatment, and pathophysiology
    • doi: 10.1212/WNL.56.1.8
    • Racette, B. A., Mcgee-Minnich, L., Moerlein, S. M., Mink, J. W., Videen, T. O., and Perlmutter, J. S. (2001). Welding-related parkinsonism: clinical features, treatment, and pathophysiology. Neurology 56, 8-13. doi: 10.1212/WNL.56.1.8
    • (2001) Neurology , vol.56 , pp. 8-13
    • Racette, B.A.1    Mcgee-Minnich, L.2    Moerlein, S.M.3    Mink, J.W.4    Videen, T.O.5    Perlmutter, J.S.6
  • 90
    • 0001782744 scopus 로고
    • Manganese poisoning in Moroccan miners
    • doi: 10.1136/oem.12.1.21
    • Rodier, J. (1955). Manganese poisoning in Moroccan miners. Br. J. Ind. Med. 12, 21-35. doi: 10.1136/oem.12.1.21
    • (1955) Br. J. Ind. Med. , vol.12 , pp. 21-35
    • Rodier, J.1
  • 91
    • 0001350374 scopus 로고
    • Liver arginase. IV. Effect of pH on kinetics of manganese-activated enzyme
    • doi: 10.1016/0003-9861(56)90144-8
    • Roholt, O. A. Jr., and Greenberg, D. M. (1956). Liver arginase. IV. Effect of pH on kinetics of manganese-activated enzyme. Arch. Biochem. Biophys. 62, 454-470. doi: 10.1016/0003-9861(56)90144-8
    • (1956) Arch. Biochem. Biophys. , vol.62 , pp. 454-470
    • Roholt Jr., O.A.1    Greenberg, D.M.2
  • 92
    • 0032819551 scopus 로고    scopus 로고
    • Manganese deposition in basal ganglia structures results from both portal-systemic shunting and liver dysfunction
    • doi: 10.1016/S0016-5085(99)70457-9
    • Rose, C., Butterworth, R. F., Zayed, J., Normandin, L., Todd, K., Michalak, A.,et al. (1999). Manganese deposition in basal ganglia structures results from both portal-systemic shunting and liver dysfunction. Gastroenterology 117, 640-644. doi: 10.1016/S0016-5085(99)70457-9
    • (1999) Gastroenterology , vol.117 , pp. 640-644
    • Rose, C.1    Butterworth, R.F.2    Zayed, J.3    Normandin, L.4    Todd, K.5    Michalak, A.6
  • 93
    • 72949094441 scopus 로고    scopus 로고
    • Are there common biochemical and molecular mechanisms controlling manganism and parkisonism
    • doi: 10.1007/s12017-009-8088-8
    • Roth, J. A. (2009). Are there common biochemical and molecular mechanisms controlling manganism and parkisonism. Neuromolecular Med. 11, 281-296. doi: 10.1007/s12017-009-8088-8
    • (2009) Neuromolecular Med. , vol.11 , pp. 281-296
    • Roth, J.A.1
  • 94
    • 0035091751 scopus 로고    scopus 로고
    • Nurr1 enhances transcription of the human dopamine transporter gene through a novel mechanism
    • doi: 10.1046/j.1471-4159.2001.00181.x
    • Sacchetti, P., Mitchell, T. R., Granneman, J. G., and Bannon, M. J. (2001). Nurr1 enhances transcription of the human dopamine transporter gene through a novel mechanism. J. Neurochem. 76, 1565-1572. doi: 10.1046/j.1471-4159.2001.00181.x
    • (2001) J. Neurochem. , vol.76 , pp. 1565-1572
    • Sacchetti, P.1    Mitchell, T.R.2    Granneman, J.G.3    Bannon, M.J.4
  • 95
    • 0032874648 scopus 로고    scopus 로고
    • Nurr1, an orphan nuclear receptor, is a transcriptional activator of endogenous tyrosine hydroxylase in neural progenitor cells derived from the adult brain.
    • Sakurada, K., Ohshima-Sakurada, M., Palmer, T. D., and Gage, F. H. (1999). Nurr1, an orphan nuclear receptor, is a transcriptional activator of endogenous tyrosine hydroxylase in neural progenitor cells derived from the adult brain. Development 126, 4017-4026.
    • (1999) Development , vol.126 , pp. 4017-4026
    • Sakurada, K.1    Ohshima-Sakurada, M.2    Palmer, T.D.3    Gage, F.H.4
  • 96
    • 57449092273 scopus 로고    scopus 로고
    • Divalent metal transporter 1 (DMT1) contributes to neurodegeneration in animal models of Parkinson's disease
    • doi: 10.1073/pnas.0804373105
    • Salazar, J., Mena, N., Hunot, S., Prigent, A., Alvarez-Fischer, D., Arredondo, M.,et al. (2008). Divalent metal transporter 1 (DMT1) contributes to neurodegeneration in animal models of Parkinson's disease. Proc. Natl. Acad. Sci. U.S.A. 105, 18578-18583. doi: 10.1073/pnas.0804373105
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 18578-18583
    • Salazar, J.1    Mena, N.2    Hunot, S.3    Prigent, A.4    Alvarez-Fischer, D.5    Arredondo, M.6
  • 97
    • 0022573477 scopus 로고
    • A brief history of the influence of trace elements on brain function.
    • Sandstead, H. H. (1986). A brief history of the influence of trace elements on brain function. Am. J. Clin. Nutr. 43, 293-298.
    • (1986) Am. J. Clin. Nutr. , vol.43 , pp. 293-298
    • Sandstead, H.H.1
  • 98
    • 9144265894 scopus 로고    scopus 로고
    • In silico identification and expression of SLC30 family genes: an expressed sequence tag data mining strategy for the characterization of zinc transporters' tissue expression.
    • doi: 10.1186/1471-2164-5-32
    • Seve, M., Chimienti, F., Devergnas, S., and Favier, A. (2004). In silico identification and expression of SLC30 family genes: an expressed sequence tag data mining strategy for the characterization of zinc transporters' tissue expression. BMC Genomics 5:32. doi: 10.1186/1471-2164-5-32
    • (2004) BMC Genomics , vol.5 , pp. 32
    • Seve, M.1    Chimienti, F.2    Devergnas, S.3    Favier, A.4
  • 99
    • 13944267769 scopus 로고    scopus 로고
    • DJ-1 is a redox-dependent molecular chaperone that inhibits α-synuclein aggregate formation.
    • doi: 10.1371/journal.pbio.0020362
    • Shendelman, S., Jonason, A., Martinat, C., Leete, T., and Abeliovich, A. (2004). DJ-1 is a redox-dependent molecular chaperone that inhibits α-synuclein aggregate formation. PLoS Biol. 2:e362. doi: 10.1371/journal.pbio.0020362
    • (2004) PLoS Biol. , vol.2
    • Shendelman, S.1    Jonason, A.2    Martinat, C.3    Leete, T.4    Abeliovich, A.5
  • 100
    • 0033933048 scopus 로고    scopus 로고
    • Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
    • doi: 10.1038/77060
    • Shimura, H., Hattori, N., Kubo, S.-I., Mizuno, Y., Asakawa, S., Minoshima, S.,et al. (2000). Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase. Nat. Genet. 25, 302-305. doi: 10.1038/77060
    • (2000) Nat. Genet. , vol.25 , pp. 302-305
    • Shimura, H.1    Hattori, N.2    Kubo, S.-I.3    Mizuno, Y.4    Asakawa, S.5    Minoshima, S.6
  • 101
    • 0030960663 scopus 로고    scopus 로고
    • Presynaptic and postsynaptic striatal dopaminergic function in patients with manganese intoxication: a positron emission tomography study
    • doi: 10.1212/WNL.48.4.1053
    • Shinotoh, H., Snow, B. J., Chu, N. S., Huang, C. C., Lu, C. S., Lee, C.,et al. (1997). Presynaptic and postsynaptic striatal dopaminergic function in patients with manganese intoxication: a positron emission tomography study. Neurology 48, 1053-1056. doi: 10.1212/WNL.48.4.1053
    • (1997) Neurology , vol.48 , pp. 1053-1056
    • Shinotoh, H.1    Snow, B.J.2    Chu, N.S.3    Huang, C.C.4    Lu, C.S.5    Lee, C.6
  • 102
    • 84877672962 scopus 로고    scopus 로고
    • Manganese-induced parkinsonism in methcathinone abusers: bio-markers of exposure and follow-up
    • doi: 10.1111/ene.12088
    • Sikk, K., Haldre, S., Aquilonius, S. M., Asser, A., Paris, M., Roose, Ä.,et al. (2013). Manganese-induced parkinsonism in methcathinone abusers: bio-markers of exposure and follow-up. Eur. J. Neurol. 20, 915-920. doi: 10.1111/ene.12088
    • (2013) Eur. J. Neurol. , vol.20 , pp. 915-920
    • Sikk, K.1    Haldre, S.2    Aquilonius, S.M.3    Asser, A.4    Paris, M.5    Roose, Ä.6
  • 103
    • 0021822906 scopus 로고
    • Manganese chloride enhances natural cell-mediated immune effector cell function: effects on macrophages
    • doi: 10.1016/0162-3109(85)90040-2
    • Smialowicz, R. J., Luebke, R. W., Rogers, R. R., Riddle, M. M., and Rowe, D. G. (1985). Manganese chloride enhances natural cell-mediated immune effector cell function: effects on macrophages. Immunopharmacology 9, 1-11. doi: 10.1016/0162-3109(85)90040-2
    • (1985) Immunopharmacology , vol.9 , pp. 1-11
    • Smialowicz, R.J.1    Luebke, R.W.2    Rogers, R.R.3    Riddle, M.M.4    Rowe, D.G.5
  • 104
    • 84872396890 scopus 로고    scopus 로고
    • Increased whole blood manganese concentrations observed in children with iron deficiency anaemia
    • doi: 10.1016/j.jtemb.2012.07.002
    • Smith, E. A., Newland, P., Bestwick, K. G., and Ahmed, N. (2012). Increased whole blood manganese concentrations observed in children with iron deficiency anaemia. J. Trace Elem. Med. Biol. 27, 65-69. doi: 10.1016/j.jtemb.2012.07.002
    • (2012) J. Trace Elem. Med. Biol. , vol.27 , pp. 65-69
    • Smith, E.A.1    Newland, P.2    Bestwick, K.G.3    Ahmed, N.4
  • 105
    • 29444437871 scopus 로고    scopus 로고
    • Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration
    • doi: 10.1073/pnas.0508052102
    • Smith, W. W., Pei, Z., Jiang, H., Moore, D. J., Liang, Y., West, A. B.,et al. (2005). Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration. Proc. Natl. Acad. Sci. U.S.A. 102, 18676-18681. doi: 10.1073/pnas.0508052102
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 18676-18681
    • Smith, W.W.1    Pei, Z.2    Jiang, H.3    Moore, D.J.4    Liang, Y.5    West, A.B.6
  • 106
    • 37349038248 scopus 로고    scopus 로고
    • Dopamine transporter relation to dopamine turnover in Parkinson's disease: a positron emission tomography study
    • doi: 10.1002/ana.21204
    • Sossi, V., De La Fuente-Fernández, R., Schulzer, M., Troiano, A. R., Ruth, T. J., and Stoessl, A. J. (2007). Dopamine transporter relation to dopamine turnover in Parkinson's disease: a positron emission tomography study. Ann. Neurol. 62, 468-474. doi: 10.1002/ana.21204
    • (2007) Ann. Neurol. , vol.62 , pp. 468-474
    • Sossi, V.1    De La Fuente-Fernández, R.2    Schulzer, M.3    Troiano, A.R.4    Ruth, T.J.5    Stoessl, A.J.6
  • 107
    • 84866288249 scopus 로고    scopus 로고
    • Dystonia with brain manganese accumulation resulting from SLC30A10 mutations: a new treatable disorder
    • doi: 10.1002/mds.25138
    • Stamelou, M., Tuschl, K., Chong, W. K., Burroughs, A. K., Mills, P. B., Bhatia, K. P.,et al. (2012). Dystonia with brain manganese accumulation resulting from SLC30A10 mutations: a new treatable disorder. Mov. Disord. 27, 1317-1322. doi: 10.1002/mds.25138
    • (2012) Mov. Disord. , vol.27 , pp. 1317-1322
    • Stamelou, M.1    Tuschl, K.2    Chong, W.K.3    Burroughs, A.K.4    Mills, P.B.5    Bhatia, K.P.6
  • 108
    • 0016703276 scopus 로고
    • On metal elements in pure pigment gallstones
    • doi: 10.1620/tjem.116.233
    • Suzuki, N., Nakamura, Y., Kobayashi, N., and Sato, T. (1975). On metal elements in pure pigment gallstones. Tohoku J. Exp. Med. 116, 233-240. doi: 10.1620/tjem.116.233
    • (1975) Tohoku J. Exp. Med. , vol.116 , pp. 233-240
    • Suzuki, N.1    Nakamura, Y.2    Kobayashi, N.3    Sato, T.4
  • 109
    • 0035813135 scopus 로고    scopus 로고
    • DJ-1 positively regulates the androgen receptor by impairing the binding of PIASxα to the receptor
    • doi: 10.1074/jbc.M101730200
    • Takahashi, K., Taira, T., Niki, T., Seino, C., Iguchi-Ariga, S. M. M., and Ariga, H. (2001). DJ-1 positively regulates the androgen receptor by impairing the binding of PIASxα to the receptor. J. Biol. Chem. 276, 37556-37563. doi: 10.1074/jbc.M101730200
    • (2001) J. Biol. Chem. , vol.276 , pp. 37556-37563
    • Takahashi, K.1    Taira, T.2    Niki, T.3    Seino, C.4    Iguchi-Ariga, S.M.M.5    Ariga, H.6
  • 110
    • 80051949129 scopus 로고    scopus 로고
    • Regulation of intracellular manganese homeostasis by Kufor-Rakeb syndrome-associated ATP13A2 protein
    • doi: 10.1074/jbc.M111.233874
    • Tan, J., Zhang, T., Jiang, L., Chi, J., Hu, D., Pan, Q.,et al. (2011). Regulation of intracellular manganese homeostasis by Kufor-Rakeb syndrome-associated ATP13A2 protein. J. Biol. Chem. 286, 29654-29662. doi: 10.1074/jbc.M111.233874
    • (2011) J. Biol. Chem. , vol.286 , pp. 29654-29662
    • Tan, J.1    Zhang, T.2    Jiang, L.3    Chi, J.4    Hu, D.5    Pan, Q.6
  • 111
    • 84858078704 scopus 로고    scopus 로고
    • Syndrome of hepatic cirrhosis, dystonia, polycythemia, and hypermanganesemia caused by mutations in SLC30A10, a manganese transporter in man
    • doi: 10.1016/j.ajhg.2012.01.018
    • Tuschl, K., Clayton, P. T., Gospe, S. M. Jr., Gulab, S., Ibrahim, S., Singhi, P.,et al. (2012). Syndrome of hepatic cirrhosis, dystonia, polycythemia, and hypermanganesemia caused by mutations in SLC30A10, a manganese transporter in man. Am. J. Hum. Genet. 90, 457-466. doi: 10.1016/j.ajhg.2012.01.018
    • (2012) Am. J. Hum. Genet. , vol.90 , pp. 457-466
    • Tuschl, K.1    Clayton, P.T.2    Gospe Jr., S.M.3    Gulab, S.4    Ibrahim, S.5    Singhi, P.6
  • 112
    • 84885953717 scopus 로고    scopus 로고
    • Inflammation alters the expression of DMT1, FPN1 and hepcidin, and it causes iron accumulation in central nervous system cells
    • doi: 10.1111/jnc.12244
    • Urrutia, P., Aguirre, P., Esparza, A., Tapia, V., Mena, N. P., Arredondo, M.,et al. (2013). Inflammation alters the expression of DMT1, FPN1 and hepcidin, and it causes iron accumulation in central nervous system cells. J. Neurochem. 126, 541-549. doi: 10.1111/jnc.12244
    • (2013) J. Neurochem. , vol.126 , pp. 541-549
    • Urrutia, P.1    Aguirre, P.2    Esparza, A.3    Tapia, V.4    Mena, N.P.5    Arredondo, M.6
  • 113
    • 2442668926 scopus 로고    scopus 로고
    • Hereditary early-onset Parkinson's disease caused by mutations in PINK1
    • doi: 10.1126/science.1096284
    • Valente, E. M., Abou-Sleiman, P. M., Caputo, V., Muqit, M. M. K., Harvey, K., Gispert, S.,et al. (2004). Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science 304, 1158-1160. doi: 10.1126/science.1096284
    • (2004) Science , vol.304 , pp. 1158-1160
    • Valente, E.M.1    Abou-Sleiman, P.M.2    Caputo, V.3    Muqit, M.M.K.4    Harvey, K.5    Gispert, S.6
  • 114
    • 0021728238 scopus 로고
    • Glutamine synthetase: the major Mn(II) enzyme in mammalian brain
    • doi: 10.1016/B978-0-12-152824-9.50021-6
    • Wedler, F. C., and Denman, R. B. (1984). Glutamine synthetase: the major Mn(II) enzyme in mammalian brain. Curr. Top. Cell. Regul. 24, 153-169. doi: 10.1016/B978-0-12-152824-9.50021-6
    • (1984) Curr. Top. Cell. Regul. , vol.24 , pp. 153-169
    • Wedler, F.C.1    Denman, R.B.2
  • 115
    • 0029083404 scopus 로고
    • Pallidal lesions in patients with liver cirrhosis: clinical and MRI evaluation
    • doi: 10.1007/BF02081027
    • Weissenborn, K., Ehrenheim, C., Hori, A., Kubicka, S., and Manns, M. P. (1995). Pallidal lesions in patients with liver cirrhosis: clinical and MRI evaluation. Metab. Brain Dis. 10, 219-231. doi: 10.1007/BF02081027
    • (1995) Metab. Brain Dis. , vol.10 , pp. 219-231
    • Weissenborn, K.1    Ehrenheim, C.2    Hori, A.3    Kubicka, S.4    Manns, M.P.5
  • 116
    • 0034514655 scopus 로고    scopus 로고
    • Ubiquitination and deubiquitination: targeting of proteins for degradation by the proteasome
    • doi: 10.1006/scdb.2000.0164
    • Wilkinson, K. D. (2000). Ubiquitination and deubiquitination: targeting of proteins for degradation by the proteasome. Semin. Cell Dev. Biol . 11, 141-148. doi: 10.1006/scdb.2000.0164
    • (2000) Semin. Cell Dev. Biol. , vol.11 , pp. 141-148
    • Wilkinson, K.D.1
  • 117
    • 1042273883 scopus 로고    scopus 로고
    • Regulation and developmental expression of the divalent metal-ion transporter in the rat brain.
    • Williams, K., Wilson, M. A., and Bressler, J. (2000). Regulation and developmental expression of the divalent metal-ion transporter in the rat brain. Cell. Mol. Biol. (Noisy-le-grand) 46, 563-571.
    • (2000) Cell. Mol. Biol. (Noisy-le-grand) , vol.46 , pp. 563-571
    • Williams, K.1    Wilson, M.A.2    Bressler, J.3
  • 118
    • 33746080412 scopus 로고    scopus 로고
    • Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin
    • doi: 10.1073/pnas.0602493103
    • Yang, Y., Gehrke, S., Imai, Y., Huang, Z., Ouyang, Y., Wang, J.-W.,et al. (2006). Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin. Proc. Natl. Acad. Sci. U.S.A. 103, 10793-10798. doi: 10.1073/pnas.0602493103
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 10793-10798
    • Yang, Y.1    Gehrke, S.2    Imai, Y.3    Huang, Z.4    Ouyang, Y.5    Wang, J.-W.6
  • 119
    • 0037468831 scopus 로고    scopus 로고
    • Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in drosophila
    • doi: 10.1016/S0896-6273(03)00143-0
    • Yang, Y., Nishimura, I., Imai, Y., Takahashi, R., and Lu, B. (2003). Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in drosophila. Neuron 37, 911-924. doi: 10.1016/S0896-6273(03)00143-0
    • (2003) Neuron , vol.37 , pp. 911-924
    • Yang, Y.1    Nishimura, I.2    Imai, Y.3    Takahashi, R.4    Lu, B.5
  • 120
    • 75949088067 scopus 로고    scopus 로고
    • Ferroportin is a manganese-responsive protein that decreases manganese cytotoxicity and accumulation
    • doi: 10.1111/j.1471-4159.2009.06534.x
    • Yin, Z., Jiang, H., Lee, E. S., Ni, M., Erikson, K. M., Milatovic, D.,et al. (2010). Ferroportin is a manganese-responsive protein that decreases manganese cytotoxicity and accumulation. J. Neurochem. 112, 1190-1198. doi: 10.1111/j.1471-4159.2009.06534.x
    • (2010) J. Neurochem. , vol.112 , pp. 1190-1198
    • Yin, Z.1    Jiang, H.2    Lee, E.S.3    Ni, M.4    Erikson, K.M.5    Milatovic, D.6
  • 121
    • 50149121528 scopus 로고    scopus 로고
    • The kinase domain of mitochondrial PINK1 faces the cytoplasm
    • doi: 10.1073/pnas.0802814105
    • Zhou, C., Huang, Y., Shao, Y., May, J., Prou, D., Perier, C.,et al. (2008). The kinase domain of mitochondrial PINK1 faces the cytoplasm. Proc. Natl. Acad. Sci. U.S.A. 105, 12022-12027. doi: 10.1073/pnas.0802814105
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 12022-12027
    • Zhou, C.1    Huang, Y.2    Shao, Y.3    May, J.4    Prou, D.5    Perier, C.6
  • 122
    • 58149358817 scopus 로고    scopus 로고
    • Dopamine auto-oxidation aggravates non-apoptotic cell death induced by over-expression of human A53T mutant alpha-synuclein in dopaminergic PC12 cells
    • doi: 10.1111/j.1471-4159.2008.05795.x
    • Zhou, Z. D., Kerk, S. Y., Xiong, G. G., and Lim, T. M. (2009). Dopamine auto-oxidation aggravates non-apoptotic cell death induced by over-expression of human A53T mutant alpha-synuclein in dopaminergic PC12 cells. J. Neurochem. 108, 601-610. doi: 10.1111/j.1471-4159.2008.05795.x
    • (2009) J. Neurochem. , vol.108 , pp. 601-610
    • Zhou, Z.D.1    Kerk, S.Y.2    Xiong, G.G.3    Lim, T.M.4
  • 123
    • 0028941961 scopus 로고
    • Trace elements in nutrition for premature infants.
    • Zlotkin, S. H., Atkinson, S., and Lockitch, G. (1995). Trace elements in nutrition for premature infants. Clin. Perinatol. 22, 223-240.
    • (1995) Clin. Perinatol. , vol.22 , pp. 223-240
    • Zlotkin, S.H.1    Atkinson, S.2    Lockitch, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.