메뉴 건너뛰기




Volumn 288, Issue 2, 2003, Pages 324-334

Nurr1 regulates dopamine synthesis and storage in MN9D dopamine cells

Author keywords

Catecholamine synthesis; Dopamine neuron; Orphan nuclear receptor; Retinoic acid; Steroid hormone receptor; Transcription factor

Indexed keywords

AROMATIC LEVO AMINO ACID DECARBOXYLASE; DOPAMINE; NUCLEAR RECEPTOR RELATED FACTOR 1; PROTEIN; RETINOIC ACID; RETINOID; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; VESICULAR MONOAMINE TRANSPORTER 2;

EID: 0043065330     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-4827(03)00216-7     Document Type: Article
Times cited : (143)

References (39)
  • 1
    • 0031104698 scopus 로고    scopus 로고
    • Dopamine synthesis, uptake, metabolism, and receptors: Relevance to gene therapy of Parkinson's disease
    • Elsworth J.D., Roth R.H. Dopamine synthesis, uptake, metabolism, and receptors relevance to gene therapy of Parkinson's disease . Exp. Neurol. 144:1997;4-9.
    • (1997) Exp. Neurol. , vol.144 , pp. 4-9
    • Elsworth, J.D.1    Roth, R.H.2
  • 2
    • 0034882629 scopus 로고    scopus 로고
    • Parkinson disease: Etiology, pathogenesis and future of gene therapy
    • Shastry B.S. Parkinson disease etiology, pathogenesis and future of gene therapy . Neurosci. Res. 41:2001;5-12.
    • (2001) Neurosci. Res. , vol.41 , pp. 5-12
    • Shastry, B.S.1
  • 3
    • 0027074637 scopus 로고
    • Identification of a new brain-specific transcription factor, NURR1
    • Law S.W., Conneely O.M., DeMayo F.J., O'Malley B.W. Identification of a new brain-specific transcription factor, NURR1. Mol. Endocrinol. 6:1992;2129-2135.
    • (1992) Mol. Endocrinol. , vol.6 , pp. 2129-2135
    • Law, S.W.1    Conneely, O.M.2    DeMayo, F.J.3    O'Malley, B.W.4
  • 4
    • 0034957480 scopus 로고    scopus 로고
    • Nuclear hormone receptors and gene expression
    • Aranda A., Pascual A. Nuclear hormone receptors and gene expression. Physiol. Rev. 81:2001;1269-1304.
    • (2001) Physiol. Rev. , vol.81 , pp. 1269-1304
    • Aranda, A.1    Pascual, A.2
  • 5
    • 0026560372 scopus 로고
    • Participation of non-zinc finger residues in DNA binding by two nuclear orphan receptors
    • Wilson T.E., Paulsen R.E., Padgett K.A., Milbrandt J. Participation of non-zinc finger residues in DNA binding by two nuclear orphan receptors. Science. 256:1992;107-110.
    • (1992) Science , vol.256 , pp. 107-110
    • Wilson, T.E.1    Paulsen, R.E.2    Padgett, K.A.3    Milbrandt, J.4
  • 6
    • 0027305861 scopus 로고
    • The orphan receptors NGFI-B and steroidogenic factor 1 establish monomer binding as a third paradigm of nuclear receptor-DNA interaction
    • Wilson T.E., Fahrner T.J., Milbrandt J. The orphan receptors NGFI-B and steroidogenic factor 1 establish monomer binding as a third paradigm of nuclear receptor-DNA interaction. Mol. Cell. Biol. 13:1993;5794-5804.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 5794-5804
    • Wilson, T.E.1    Fahrner, T.J.2    Milbrandt, J.3
  • 7
    • 0028946634 scopus 로고
    • A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1
    • Perlmann T., Jansson L. A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1. Genes Dev. 9:1995;769-782.
    • (1995) Genes Dev. , vol.9 , pp. 769-782
    • Perlmann, T.1    Jansson, L.2
  • 8
    • 0029002298 scopus 로고
    • Unique response pathways are established by allosteric interactions among nuclear hormone receptors
    • Forman B.M., Umesono K., Chen J., Evans R.M. Unique response pathways are established by allosteric interactions among nuclear hormone receptors. Cell. 81:1995;541-550.
    • (1995) Cell , vol.81 , pp. 541-550
    • Forman, B.M.1    Umesono, K.2    Chen, J.3    Evans, R.M.4
  • 10
    • 0032747825 scopus 로고    scopus 로고
    • Heterodimerization between members of the Nur subfamily of orphan nuclear receptors as a novel mechanism for gene activation
    • Maira M., Martens C., Philips A., Drouin J. Heterodimerization between members of the Nur subfamily of orphan nuclear receptors as a novel mechanism for gene activation. Mol. Cell. Biol. 19:1999;7549-7557.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 7549-7557
    • Maira, M.1    Martens, C.2    Philips, A.3    Drouin, J.4
  • 11
    • 0029857001 scopus 로고    scopus 로고
    • Retinoid X receptor heterodimerization and developmental expression distinguish the orphan nuclear receptors NGFI-B, Nurr1, and Nor1
    • Zetterstrom R.H., Solomin L., Mitsiadis T., Olson L., Perlmann T. Retinoid X receptor heterodimerization and developmental expression distinguish the orphan nuclear receptors NGFI-B, Nurr1, and Nor1. Mol. Endocrinol. 10:1996;1656-1666.
    • (1996) Mol. Endocrinol. , vol.10 , pp. 1656-1666
    • Zetterstrom, R.H.1    Solomin, L.2    Mitsiadis, T.3    Olson, L.4    Perlmann, T.5
  • 12
    • 0000190727 scopus 로고    scopus 로고
    • Cellular expression of the immediate early transcription factors Nurr1 and NGFI-B suggests a gene regulatory role in several brain regions including the nigrostriatal dopamine system
    • Zetterstrom R.H., Williams R., Perlmann T., Olson L. Cellular expression of the immediate early transcription factors Nurr1 and NGFI-B suggests a gene regulatory role in several brain regions including the nigrostriatal dopamine system. Brain Res. Mol. Brain Res. 41:1996;111-120.
    • (1996) Brain Res. Mol. Brain Res. , vol.41 , pp. 111-120
    • Zetterstrom, R.H.1    Williams, R.2    Perlmann, T.3    Olson, L.4
  • 14
    • 0031805754 scopus 로고    scopus 로고
    • Dopamine biosynthesis is selectively abolished in substantia nigra/ventral tegmental area but not in hypothalamic neurons in mice with targeted disruption of the Nurr1 gene
    • Castillo S.O., Baffi J.S., Palkovits M., Goldstein D.S., Kopin I.J., Witta J., Magnuson M.A., Nikodem V.M. Dopamine biosynthesis is selectively abolished in substantia nigra/ventral tegmental area but not in hypothalamic neurons in mice with targeted disruption of the Nurr1 gene. Mol. Cell. Neurosci. 11:1998;36-46.
    • (1998) Mol. Cell. Neurosci. , vol.11 , pp. 36-46
    • Castillo, S.O.1    Baffi, J.S.2    Palkovits, M.3    Goldstein, D.S.4    Kopin, I.J.5    Witta, J.6    Magnuson, M.A.7    Nikodem, V.M.8
  • 19
    • 0032854449 scopus 로고    scopus 로고
    • Characterization of MPP(+)-induced cell death in a dopaminergic neuronal cell line: Role of macromolecule synthesis, cytosolic calcium, caspase, and Bcl-2-related proteins
    • Choi W.S., Canzoniero L.M., Sensi S.L., O'Malley K.L., Gwag B.J., Sohn S., Kim J.E., Oh T.H., Lee E.B., Oh Y.J. Characterization of MPP(+)-induced cell death in a dopaminergic neuronal cell line role of macromolecule synthesis, cytosolic calcium, caspase, and Bcl-2-related proteins . Exp. Neurol. 159:1999;274-282.
    • (1999) Exp. Neurol. , vol.159 , pp. 274-282
    • Choi, W.S.1    Canzoniero, L.M.2    Sensi, S.L.3    O'Malley, K.L.4    Gwag, B.J.5    Sohn, S.6    Kim, J.E.7    Oh, T.H.8    Lee, E.B.9    Oh, Y.J.10
  • 20
    • 0034812098 scopus 로고    scopus 로고
    • MPP(+) downregulates mitochondrially encoded gene transcripts and their activities in dopaminergic neuronal cells: Protective role of Bcl-2
    • Kim H.E., Yoon S.Y., Lee J.E., Choi W.S., Jin B.K., Oh T.H., Markelonis G.J., Chun S.Y., Oh Y.J. MPP(+) downregulates mitochondrially encoded gene transcripts and their activities in dopaminergic neuronal cells protective role of Bcl-2 . Biochem. Biophys. Res. Commun. 286:2001;659-665.
    • (2001) Biochem. Biophys. Res. Commun. , vol.286 , pp. 659-665
    • Kim, H.E.1    Yoon, S.Y.2    Lee, J.E.3    Choi, W.S.4    Jin, B.K.5    Oh, T.H.6    Markelonis, G.J.7    Chun, S.Y.8    Oh, Y.J.9
  • 21
    • 0035964742 scopus 로고    scopus 로고
    • Overexpression of calbindin-D28K induces neurite outgrowth in dopaminergic neuronal cells via activation of p38 MAPK
    • Choi W.S., Chun S.Y., Markelonis G.J., Oh T.H., Oh Y.J. Overexpression of calbindin-D28K induces neurite outgrowth in dopaminergic neuronal cells via activation of p38 MAPK. Biochem. Biophys. Res. Commun. 287:2001;656-661.
    • (2001) Biochem. Biophys. Res. Commun. , vol.287 , pp. 656-661
    • Choi, W.S.1    Chun, S.Y.2    Markelonis, G.J.3    Oh, T.H.4    Oh, Y.J.5
  • 22
    • 0030600002 scopus 로고    scopus 로고
    • Glial-derived neurotrophic factor (GDNF) induced morphological differentiation of an immortalized monoclonal hybrid dopaminergic cell line of mesencephalic neuronal origin
    • Heller A., Price S., Won L. Glial-derived neurotrophic factor (GDNF) induced morphological differentiation of an immortalized monoclonal hybrid dopaminergic cell line of mesencephalic neuronal origin. Brain Res. 725:1996;132-136.
    • (1996) Brain Res. , vol.725 , pp. 132-136
    • Heller, A.1    Price, S.2    Won, L.3
  • 23
    • 0029916806 scopus 로고    scopus 로고
    • PTX-sensitive regulation of neurite outgrowth by the dopamine D3 receptor
    • Swarzenski B.C., O'Malley K.L., Todd R.D. PTX-sensitive regulation of neurite outgrowth by the dopamine D3 receptor. NeuroReport. 7:1996;573-576.
    • (1996) NeuroReport , vol.7 , pp. 573-576
    • Swarzenski, B.C.1    O'Malley, K.L.2    Todd, R.D.3
  • 24
    • 0030071203 scopus 로고    scopus 로고
    • Overexpression of Bcl-2 in a murine dopaminergic neuronal cell line leads to neurite outgrowth
    • Oh Y.J., Swarzenski B.C., O'Malley K.L. Overexpression of Bcl-2 in a murine dopaminergic neuronal cell line leads to neurite outgrowth. Neurosci. Lett. 202:1996;161-164.
    • (1996) Neurosci. Lett. , vol.202 , pp. 161-164
    • Oh, Y.J.1    Swarzenski, B.C.2    O'Malley, K.L.3
  • 25
    • 0035900751 scopus 로고    scopus 로고
    • Induction of cell cycle arrest and morphological differentiation by Nurr1 and retinoids in dopamine MN9D cells
    • Castro D.S., Hermanson E., Joseph B., Wallen A., Aarnisalo P., Heller A., Perlmann T. Induction of cell cycle arrest and morphological differentiation by Nurr1 and retinoids in dopamine MN9D cells. J. Biol. Chem. 276:2001;43277-43284.
    • (2001) J. Biol. Chem. , vol.276 , pp. 43277-43284
    • Castro, D.S.1    Hermanson, E.2    Joseph, B.3    Wallen, A.4    Aarnisalo, P.5    Heller, A.6    Perlmann, T.7
  • 26
    • 0032874648 scopus 로고    scopus 로고
    • Nurr1, an orphan nuclear receptor, is a transcriptional activator of endogenous tyrosine hydroxylase in neural progenitor cells derived from the adult brain
    • Sakurada K., Ohshima-Sakurada M., Palmer T.D., Gage F.H. Nurr1, an orphan nuclear receptor, is a transcriptional activator of endogenous tyrosine hydroxylase in neural progenitor cells derived from the adult brain. Development. 126:1999;4017-4026.
    • (1999) Development , vol.126 , pp. 4017-4026
    • Sakurada, K.1    Ohshima-Sakurada, M.2    Palmer, T.D.3    Gage, F.H.4
  • 27
    • 0028912476 scopus 로고
    • Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development
    • Zhou Q.Y., Quaife C.J., Palmiter R.D. Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development. Nature. 374:1995;640-643.
    • (1995) Nature , vol.374 , pp. 640-643
    • Zhou, Q.Y.1    Quaife, C.J.2    Palmiter, R.D.3
  • 28
    • 0033579988 scopus 로고    scopus 로고
    • An isoform of Nurr1 functions as a negative inhibitor of the NGFI-B family signaling
    • Ohkura N., Hosono T., Maruyama K., Tsukada T., Yamaguchi K. An isoform of Nurr1 functions as a negative inhibitor of the NGFI-B family signaling. Biochim. Biophys. Acta. 1444:1999;69-79.
    • (1999) Biochim. Biophys. Acta , vol.1444 , pp. 69-79
    • Ohkura, N.1    Hosono, T.2    Maruyama, K.3    Tsukada, T.4    Yamaguchi, K.5
  • 30
    • 0029054992 scopus 로고
    • Time-course of trimethyltin effects on the monoaminergic systems of the rat brain
    • Andersson H., Luthman J., Lindqvist E., Olson L. Time-course of trimethyltin effects on the monoaminergic systems of the rat brain. Neurotoxicology. 16:1995;201-210.
    • (1995) Neurotoxicology , vol.16 , pp. 201-210
    • Andersson, H.1    Luthman, J.2    Lindqvist, E.3    Olson, L.4
  • 31
    • 0034034739 scopus 로고    scopus 로고
    • A second independent pathway for development of mesencephalic dopaminergic neurons requires Lmx1b
    • Smidt M.P., Asbreuk C.H., Cox J.J., Chen H., Johnson R.L., Burbach J.P. A second independent pathway for development of mesencephalic dopaminergic neurons requires Lmx1b. Nature Neurosci. 3:2000;337-341.
    • (2000) Nature Neurosci. , vol.3 , pp. 337-341
    • Smidt, M.P.1    Asbreuk, C.H.2    Cox, J.J.3    Chen, H.4    Johnson, R.L.5    Burbach, J.P.6
  • 32
    • 0034637020 scopus 로고    scopus 로고
    • Identification of a potential nurr1 response element that activates the tyrosine hydroxylase gene promoter in cultured cells
    • Iwawaki T., Kohno K., Kobayashi K. Identification of a potential nurr1 response element that activates the tyrosine hydroxylase gene promoter in cultured cells. Biochem. Biophys. Res. Commun. 274:2000;590-595.
    • (2000) Biochem. Biophys. Res. Commun. , vol.274 , pp. 590-595
    • Iwawaki, T.1    Kohno, K.2    Kobayashi, K.3
  • 35
    • 0033560875 scopus 로고    scopus 로고
    • Vesicular monoamine transporter-2 and aromatic L-amino acid decarboxylase enhance dopamine delivery after L-3, 4-dihydroxyphenylalanine administration in parkinsonian rats
    • Lee W.Y., Chang J.W., Nemeth N.L., Kang U.J. Vesicular monoamine transporter-2 and aromatic L-amino acid decarboxylase enhance dopamine delivery after L-3, 4-dihydroxyphenylalanine administration in parkinsonian rats. J. Neurosci. 19:1999;3266-3274.
    • (1999) J. Neurosci. , vol.19 , pp. 3266-3274
    • Lee, W.Y.1    Chang, J.W.2    Nemeth, N.L.3    Kang, U.J.4
  • 36
    • 0032964181 scopus 로고    scopus 로고
    • L-deprenyl induces aromatic L-amino acid decarboxylase (AADC) mRNA in the rat substantia nigra and ventral tegmentum. An in situ hybridization study
    • Li X.M., Juorio A.V., Qi J., Boulton A.A. L-deprenyl induces aromatic L-amino acid decarboxylase (AADC) mRNA in the rat substantia nigra and ventral tegmentum. An in situ hybridization study. Mol. Chem. Neuropathol. 35:1998;149-155.
    • (1998) Mol. Chem. Neuropathol. , vol.35 , pp. 149-155
    • Li, X.M.1    Juorio, A.V.2    Qi, J.3    Boulton, A.A.4
  • 39
    • 0035017743 scopus 로고    scopus 로고
    • Protection of intracellular dopamine cytotoxicity by dopamine disposition and metabolism factors
    • Weingarten P., Zhou Q.Y. Protection of intracellular dopamine cytotoxicity by dopamine disposition and metabolism factors. J. Neurochem. 77:2001;776-785.
    • (2001) J. Neurochem. , vol.77 , pp. 776-785
    • Weingarten, P.1    Zhou, Q.Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.