메뉴 건너뛰기




Volumn 6, Issue 248, 2014, Pages

Genetic validation of a therapeutic target in a mouse model of ALS

Author keywords

[No Author keywords available]

Indexed keywords

PROSTAGLANDIN RECEPTOR; PROSTANOID D RECEPTOR 1, MOUSE;

EID: 84905990888     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3009351     Document Type: Article
Times cited : (28)

References (70)
  • 1
    • 0028097839 scopus 로고
    • A controlled trial of riluzole in amyotrophic lateral sclerosis
    • ALS/Riluzole Study Group
    • G. Bensimon, L. Lacomblez, V. Meininger, A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group. N. Engl. J. Med. 330, 585-591 (1994).
    • (1994) N. Engl. J. Med. , vol.330 , pp. 585-591
    • Bensimon, G.1    Lacomblez, L.2    Meininger, V.3
  • 12
    • 0036076642 scopus 로고    scopus 로고
    • Fibrillar inclusions and motor neuron degeneration in transgenic mice expressing superoxide dismutase 1 with a disrupted copper-binding site
    • J. Wang, G. Xu, V. Gonzales, M. Coonfield, D. Fromholt, N. G. Copeland, N. A. Jenkins, D. R. Borchelt, Fibrillar inclusions and motor neuron degeneration in transgenic mice expressing superoxide dismutase 1 with a disrupted copper-binding site. Neurobiol. Dis. 10, 128-138 (2002).
    • (2002) Neurobiol. Dis. , vol.10 , pp. 128-138
    • Wang, J.1    Xu, G.2    Gonzales, V.3    Coonfield, M.4    Fromholt, D.5    Copeland, N.G.6    Jenkins, N.A.7    Borchelt, D.R.8
  • 13
    • 0029053881 scopus 로고
    • An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
    • P. C. Wong, C. A. Pardo, D. R. Borchelt, M. K. Lee, N. G. Copeland, N. A. Jenkins, S. S. Sisodia, D. W. Cleveland, D. L. Price, An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron 14, 1105-1116 (1995).
    • (1995) Neuron , vol.14 , pp. 1105-1116
    • Wong, P.C.1    Pardo, C.A.2    Borchelt, D.R.3    Lee, M.K.4    Copeland, N.G.5    Jenkins, N.A.6    Sisodia, S.S.7    Cleveland, D.W.8    Price, D.L.9
  • 14
    • 0028888945 scopus 로고
    • Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis
    • M. E. Ripps, G. W. Huntley, P. R. Hof, J. H. Morrison, J. W. Gordon, Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis. Proc. Natl. Acad. Sci. U.S.A. 92, 689-693 (1995).
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 689-693
    • Ripps, M.E.1    Huntley, G.W.2    Hof, P.R.3    Morrison, J.H.4    Gordon, J.W.5
  • 16
    • 33749056809 scopus 로고    scopus 로고
    • ALS: A disease of motor neurons and their nonneuronal neighbors
    • S. Boillée, C. Vande Velde, D. W. Cleveland, ALS: A disease of motor neurons and their nonneuronal neighbors. Neuron 52, 39-59 (2006).
    • (2006) Neuron , vol.52 , pp. 39-59
    • Boillée, S.1    Vande Velde, C.2    Cleveland, D.W.3
  • 17
    • 34247473080 scopus 로고    scopus 로고
    • Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model
    • F. P. Di Giorgio, M. A. Carrasco, M. C. Siao, T. Maniatis, K. Eggan, Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model. Nat. Neurosci. 10, 608-614 (2007).
    • (2007) Nat. Neurosci. , vol.10 , pp. 608-614
    • Di Giorgio, F.P.1    Carrasco, M.A.2    Siao, M.C.3    Maniatis, T.4    Eggan, K.5
  • 18
    • 56549096129 scopus 로고    scopus 로고
    • Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation
    • F. P. Di Giorgio, G. L. Boulting, S. Bobrowicz, K. C. Eggan, Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation. Cell Stem Cell 3, 637-648 (2008).
    • (2008) Cell Stem Cell , vol.3 , pp. 637-648
    • Di Giorgio, F.P.1    Boulting, G.L.2    Bobrowicz, S.3    Eggan, K.C.4
  • 36
    • 78149488365 scopus 로고    scopus 로고
    • A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells
    • M. C. Marchetto, C. Carromeu, A. Acab, D. Yu, G. W. Yeo, Y. Mu, G. Chen, F. H. Gage, A. R. Muotri, A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells. Cell 143, 527-539 (2010).
    • (2010) Cell , vol.143 , pp. 527-539
    • Marchetto, M.C.1    Carromeu, C.2    Acab, A.3    Yu, D.4    Yeo, G.W.5    Mu, Y.6    Chen, G.7    Gage, F.H.8    Muotri, A.R.9
  • 40
    • 0024547972 scopus 로고
    • The classification of prostaglandin DP-receptors in platelets and vasculature using BW A868C, a novel, selective and potent competitive antagonist
    • H. Giles, P. Leff, M. L. Bolofo, M. G. Kelly, A. D. Robertson, The classification of prostaglandin DP-receptors in platelets and vasculature using BW A868C, a novel, selective and potent competitive antagonist. Br. J. Pharmacol. 96, 291-300 (1989).
    • (1989) Br. J. Pharmacol. , vol.96 , pp. 291-300
    • Giles, H.1    Leff, P.2    Bolofo, M.L.3    Kelly, M.G.4    Robertson, A.D.5
  • 43
    • 0020450362 scopus 로고
    • Identification and characterisation of a prostacyclin-like receptor in bovine coronary arteries using a specific and stable prostacyclin analogue, ciloprost, as radioactive ligand
    • M. H. Town, E. Schillinger, A. Speckenbach, G. Prior, Identification and characterisation of a prostacyclin-like receptor in bovine coronary arteries using a specific and stable prostacyclin analogue, ciloprost, as radioactive ligand. Prostaglandins 24, 61-72 (1982).
    • (1982) Prostaglandins , vol.24 , pp. 61-72
    • Town, M.H.1    Schillinger, E.2    Speckenbach, A.3    Prior, G.4
  • 44
    • 0029134144 scopus 로고
    • Molecular cloning and characterization of the human prostanoid DP receptor
    • Y. Boie, N. Sawyer, D. M. Slipetz, K. M. Metters, M. Abramovitz, Molecular cloning and characterization of the human prostanoid DP receptor. J. Biol. Chem. 270, 18910-18916 (1995).
    • (1995) J. Biol. Chem. , vol.270 , pp. 18910-18916
    • Boie, Y.1    Sawyer, N.2    Slipetz, D.M.3    Metters, K.M.4    Abramovitz, M.5
  • 45
    • 0030006864 scopus 로고    scopus 로고
    • Identification of prostanoid receptors in rabbit non-pigmented ciliary epithelial cells
    • P. Bhattacherjee, N. Jacobs, M. Coca-Prados, C. Paterson, Identification of prostanoid receptors in rabbit non-pigmented ciliary epithelial cells. Exp. Eye Res. 62, 491-498 (1996).
    • (1996) Exp. Eye Res. , vol.62 , pp. 491-498
    • Bhattacherjee, P.1    Jacobs, N.2    Coca-Prados, M.3    Paterson, C.4
  • 46
    • 0034012172 scopus 로고    scopus 로고
    • Affinities, selectivities, potencies, and intrinsic activities of natural and synthetic prostanoids using endogenous receptors: Focus on DP class prostanoids
    • N. A. Sharif, J. Y. Crider, S. X. Xu, G. W. Williams, Affinities, selectivities, potencies, and intrinsic activities of natural and synthetic prostanoids using endogenous receptors: Focus on DP class prostanoids. J. Pharmacol. Exp. Ther. 293, 321-328 (2000).
    • (2000) J. Pharmacol. Exp. Ther. , vol.293 , pp. 321-328
    • Sharif, N.A.1    Crider, J.Y.2    Xu, S.X.3    Williams, G.W.4
  • 49
    • 0032903864 scopus 로고    scopus 로고
    • Prostaglandin DP receptors positively coupled to adenylyl cyclase in embryonic bovine tracheal (EBTr) cells: Pharmacological characterization using agonists and antagonists
    • J. Y. Crider, B. W. Griffin, N. A. Sharif, Prostaglandin DP receptors positively coupled to adenylyl cyclase in embryonic bovine tracheal (EBTr) cells: Pharmacological characterization using agonists and antagonists. Br. J. Pharmacol. 127, 204-210 (1999).
    • (1999) Br. J. Pharmacol. , vol.127 , pp. 204-210
    • Crider, J.Y.1    Griffin, B.W.2    Sharif, N.A.3
  • 52
    • 79953288489 scopus 로고    scopus 로고
    • H2 inflammation in the pathogenesis of bronchial asthma
    • H2 inflammation in the pathogenesis of bronchial asthma. Korean J. Intern. Med. 26, 8-18 (2011).
    • (2011) Korean J. Intern. Med. , vol.26 , pp. 8-18
    • Arima, M.1    Fukuda, T.2
  • 56
    • 0036269810 scopus 로고    scopus 로고
    • Differential expression of inflammation-and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis
    • T. Yoshihara, S. Ishigaki, M. Yamamoto, Y. Liang, J. Niwa, H. Takeuchi, M. Doyu, G. Sobue, Differential expression of inflammation-and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis. J. Neurochem. 80, 158-167 (2002).
    • (2002) J. Neurochem. , vol.80 , pp. 158-167
    • Yoshihara, T.1    Ishigaki, S.2    Yamamoto, M.3    Liang, Y.4    Niwa, J.5    Takeuchi, H.6    Doyu, M.7    Sobue, G.8
  • 58
    • 0036062628 scopus 로고    scopus 로고
    • Temporal patterns of cytokine and apoptosis-related gene expression in spinal cords of the G93A-SOD1 mouse model of amyotrophic lateral sclerosis
    • K. Hensley, R. A. Floyd, B. Gordon, S. Mou, Q. N. Pye, C. Stewart, M. West, K. Williamson, Temporal patterns of cytokine and apoptosis-related gene expression in spinal cords of the G93A-SOD1 mouse model of amyotrophic lateral sclerosis. J. Neurochem. 82, 365-374 (2002).
    • (2002) J. Neurochem. , vol.82 , pp. 365-374
    • Hensley, K.1    Floyd, R.A.2    Gordon, B.3    Mou, S.4    Pye, Q.N.5    Stewart, C.6    West, M.7    Williamson, K.8
  • 59
    • 0035500386 scopus 로고    scopus 로고
    • Cytokine upregulation in a murine model of familial amyotrophic lateral sclerosis
    • J. L. Elliott, Cytokine upregulation in a murine model of familial amyotrophic lateral sclerosis. Brain Res. Mol. Brain Res. 95, 172-178 (2001).
    • (2001) Brain Res. Mol. Brain Res. , vol.95 , pp. 172-178
    • Elliott, J.L.1
  • 60
    • 0033018506 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase up-regulation in a transgenic mouse model of familial amyotrophic lateral sclerosis
    • G. Almer, S. Vukosavic, N. Romero, S. Przedborski, Inducible nitric oxide synthase up-regulation in a transgenic mouse model of familial amyotrophic lateral sclerosis. J. Neurochem. 72, 2415-2425 (1999).
    • (1999) J. Neurochem. , vol.72 , pp. 2415-2425
    • Almer, G.1    Vukosavic, S.2    Romero, N.3    Przedborski, S.4
  • 65
    • 30744441143 scopus 로고    scopus 로고
    • 2 mediates neuronal damage by amyloid-β or prions which activates microglial cells
    • 2 mediates neuronal damage by amyloid-β or prions which activates microglial cells. Neuropharmacology 50, 229-237 (2006).
    • (2006) Neuropharmacology , vol.50 , pp. 229-237
    • Bate, C.1    Kempster, S.2    Williams, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.