Modulatory roles for integrin activation and the synergy site of fibronectin during matrix assembly

Molecular Biology of the Cell

Volumn 8, Issue 12, 1997, Pages 2563-2573

  Sechler, Jan L ^a   Corbett, Siobhan A ^a,b   Schwarzbauer, Jean E ^a  

^a PRINCETON UNIVERSITY   (United States)

^b ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRONECTIN; INTEGRIN;

ARTICLE; CELL FUNCTION; CELL TRANSFORMATION; EXTRACELLULAR MATRIX; GASTRULATION; GENE MUTATION; GENETIC RECOMBINATION; HUMAN; HUMAN CELL; LIGAND BINDING; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN PROTEIN INTERACTION; SECOND MESSENGER;

EID: 0030659845     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.8.12.2563     Document Type: Article

References (52)

1. Aguirre, K.M., McCormick, R.J., and Schwarzbauer, J.E. (1994). Fibronectin self-association is mediated by complementary sites within the amino-terminal one-third of the molecule. J. Biol. Chem. 269, 27863-27868.
2. Akiyama, S.K., Yamada, S.S., Chen, W.-T., and Yamada, K.M. (1989). Analysis of fibronectin receptor function with monoclonal antibodies: roles in cell adhesion, migration, matrix assembly, and cytoskeletal organization. J. Cell Biol. 109, 863-875.
3. Ali, I.U., Mautner, V.M., Lanza, R.P., and Hynes, R.O. (1977). Restoration of a normal morphology, adhesion, and cytoskeleton in transformed cells by addition of a transformation-sensitive surface protein. Cell 11, 115-126.
4. Aota, S., Nomiau, M., and Yamada, K.M. (1994). The short amino acid sequence Pro-His-Ser-Arg-Asn in human fibronectin enhances cell-adhesive function. J. Biol. Chem. 269, 24756-24761.
5. Aota, S., Toshihiko, T., and Yamada, K.M. (1991). Characterization of regions of fibronectin besides the arginine-glycine-aspartic acid sequence required for adhesive function of the cell-binding domain using site-directed mutagenesis. J. Biol. Chem. 266, 15938-15943.
6. Arroyo, A.G., Sanchez-Mateos, P., Campanero, M.R., I. Martin-Padura, I., Dejana, E., and Sanchez-Madrid, F. (1992). Regulation of the VLA integrin-ligand interactions through the beta 1 subunit. J. Cell Biol. 127, 659-670.
7. Assoian, R.K. (1997). Anchorage-dependent cell cycle progression. J. Cell Biol. 136, 1-4.
8. Bazzoni, G., Shih, D.-T., Buck, C.A., and Hemler, M.E. (1995). Mono-clonal antibody 9EG7 defines a novel β1 integrin epitope induced by soluble ligand and manganese, but inhibited by calcium. J. Biol. Chem. 270, 25570-25577.
9. Bowditch, R.D., Halloran, C.E., Aota, S., Obara, M., Plow, E.F., Yamada, K.M., and Ginsberg, M.H. (1991). Integrin αIIIβ3 (platelet GPIIIb-IIIa) recognizes multiple sites in fibronectin. J. Biol. Chem. 266, 23323-23328.
10. Bowditch, R.D., Hariharan, M., Tominna, E.F., Smith, J.W., Yamada, K.M., Getzoff, E.D., and Ginsberg, M.H. (1994). Identification of a novel integrin binding site in fibronectin: differential utilization by β3 integrins. J. Biol. Chem. 269, 10856-10863.
11. Brown, P.J., and Juliano, R.L. (1985). Selective inhibition of fibronectin-mediated cell adhesion by monoclonal antibodies to a cell-surface glycoprotein. Science 228, 1448-1451.
12. Brown, P.J., and Juliano, R.L. (1988). Monoclonal antibodies to distinctive epitopes on the α and α subunits of the fibronectin receptor. Exp. Cell Res. 177, 303-318.
13. Danen, E.J., Aota, S., vanKraats, A.A., Yamada, K.M., Ruiter, D.J., and vanMuijen, G.N.P. (1995). Requirement for the synergy site for cell adhesion to fibronectin depends on the activation state of integrin α5β1. J. Biol. Chem. 270, 21612-21618.
14. Danilov, Y.N., and Juliano, R.L. (1989). Phorbol ester modulation of integrin-mediated cell adhesion: a postreceptor event. J. Cell Biol. 108, 1925-1933.
15. Fassler, R., Georges-Labouesse, E., and Hirsch, E. (1996). Genetic analysis of integrin function in mice. Curr. Opin. Cell Biol. 8, 641-646.
16. Faull, R.J., Kovach, N.L., Harlan, J.M., and Ginsberg, M.H. (1993). Affinity modulation of integrin α5β1: regulation of the functional response by soluble fibronectin. J. Cell Biol. 222, 155-162.
17. Faull, R.J., Kovach, N.L., Harlan, J.M., and Ginsberg, M.H. (1994). Stimulation of integrin-mediated adhesion of T-lymphocytes and monocytes: two mechanisms with divergent biological consequences. J. Exp. Med. 179, 1307-1316.
18. Fogerty, F.J., Akiyama, S.K., Yamada, K.M., and Mosher, D.F. (1990). Inhibition of binding of fibronectin to matrix assembly sites by anti-integrin (alpha 5 beta 1) antibodies. J. Cell Biol. 111, 699-708.
19. Frelinger, A.L., III, Du, X., Plow, E.F., and Ginsberg, M.H. (1991). Monoclonal antibodies to ligand-occupied conformers of integrin αIIbβ3 (glycoprotein IIb-IIIa) alter receptor affinity, specificity, and function. J. Biol. Chem. 266, 17106-17111.
20. Gailit, J., and Ruoslahti, E. (1988). Regulation of fibronectin receptor affinity by divalent cations. J. Biol. Chem. 263, 12927-12932.
21. George, E.L., Georges-Labouesse, E.N., Patel-King, R.S., Rayburn, H., and Hynes, R.O. (1993). Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin. Development 229, 1079-1091.
22. Giancotti, F.G., and Ruoslahti, E. (1990). Elevated levels of the α5βl fibronectin receptor suppress the transformed phenotype of the Chinese hamster ovary cells. Cell 60, 849-859.
23. Ginsberg, M.H., Du, X., and Plow, E.F. (1992). Inside-out integrin signaling. Curr. Opin. Cell Biol. 4, 766-771.
24. Hocking, D.C., Sottile, J., and McKeown-Longo, P.J. (1994). Fibronectin's III-1 module contains a conformation-dependent binding site for the amino-terminal region of fibronectin. J. Biol. Chem. 269, 19183-19191.
25. Humphries, M.J. (1996). Integrin activation: the link between ligand binding and signal transduction. Curr. Opin. Cell Biol. 8, 632-640.
26. Hynes, R.O. (1990). Fibronectins, New York: Springer-Verlag.
27. Hynes, R.O. (1992). Integrins: versatility, modulation, and signaling in cell adhesion. Cell 69, 11-25.
28. Jockusch, B.M., and Rudiger, M. (1996). Crosstalk between cell adhesion molecules: vinculin as a paradigm for regulation by conformation. Trends Cell Biol. 6, 311-315.
29. Kovach, N.L., Carlos, T.M., Yee, E., and Harlan, J.M. (1992). A monoclonal antibody to beta 1 integrin (CD29) stimulates VLA-dependent adherence of leukocytes to human umbilical vein endothelial cells and matrix components. J. Cell Biol. 326, 499-509.
30. McDonald, J.A. (1988). Extracellular matrix assembly. Annu. Rev. Cell Biol. 4, 183-207.
31. Morla, A., and Rouslahti, E. (1992). A fibronectin self-assembly site involved in fibronectin matrix assembly: reconstruction in a synthetic peptide. J. Cell Biol. 118, 421-429.
32. Mosher, D.F. (1993). Assembly of fibronectin into extracellular matrix. Curr. Opin. Struct. Biol. 3, 214-222.
33. Mould, A.P. (1996). Getting integrins into shape: recent insights into how integrin activity is regulated by conformational changes. J. Cell Sci. 209, 2613-2618.
34. Mould, A.P., Akiyama, S., and Humphries, M.J. (1995). Regulation of integrin α5β1-fibronectin interactions by divalent cations. J. Biol. Chem. 270, 26270-26277.
35. Nagai, T., Yamakawa, N., Aota, S., Yamada, S.S., Akiyama, S.K., Olden, K., and Yamada, K.M. (1991). Monoclonal antibody characterization of two distant sites required for function in cell adhesion, cell migration, and matrix assembly. J. Cell Biol. 114, 1295-1305.
36. O'Toole, T.E., Loftus, J.C., Du, X., Glass, A.A., Ruggeri, Z.M., Shattil, S.J., Plow, E.P., and Ginsberg, M.H. (1990). Affinity modulation of the alpha lib beta 3 integrin (platelet GPIIb-IIIa) is an intrinsic property of the receptor. Cell Regul. 1, 883-893.
37. Ramos, J.W., and DeSimone, D.W. (1996). Xenopus embryonic cell adhesion to fibronectin: position-specific activation of RGD/synergy site-dependent migratory behavior at gastrulation. J. Cell Biol. 234, 227-240.
38. Roman, J., R.M. LaChance, Broekelmann, T.J., Kennedy, C.J.R., Wagner, E.A., Carter, W.G., and McDonald, J.A. (1989). The fibronectin receptor is organized by extracellular matrix fibronectin: implications for oncogenic transformation and for cell recognition of fibronectin matrices. J. Cell Biol. 108, 2529-2543.
39. Ruoslahti, E. (1991). Integrins. J. Clin. Invest. 87, 1-5.
40. Schwarzbauer, J.E. (1991). Identification of the fibronectin sequences required for assembly of a fibrillar matrix. J. Cell Biol. 223, 1463-1473.
41. Sechler, J.L., Takada, Y., and Schwarzbauer, J.E. (1996). Altered rate of fibronectin matrix assembly by deletion of the first type III repeats. J. Cell. Biol. 234, 575-585.
42. Sechler, J.L., and Schwarzbauer, J.E. (1997). Coordinate regulation of fibronectin fibril assembly and actin stress fiber formation. Cell Adhes. Commun. 4, 413-424.
43. Somers, C.E., and Mosher, D.E. (1993). Protein kinase C modulation of fibronectin matrix assembly. J. Biol. Chem. 268, 22277-22280.
44. Ugarova, T.P., Zamarron, C., Veklich, Y., Bowditch, R.D., Ginsberg, M.H., Weisel, J.W., and Plow, E.F. (1995). Conformational transitions in the cell binding domain of fibronectin. Biochemistry 34, 4457-4466.
45. Vuori, K., and Ruoslahti, E. (1993). Activation of protein kinase C precedes α5β1 integrin-mediated cell spreading on fibronectin. J. Biol. Chem. 265, 21459-21462.
46. Wennerberg, K., Lohikangas, L., Gullberg, D., Pfaff, M., Johansson, S., and Fassler, R. (1996). β1 integrin-dependent and -independent polymerization of fibronectin. J. Cell Biol. 132, 227-238.
47. Wu, C., Hughes, P.E., Ginsberg, M.H., and McDonald, J.A. (1996). Identification of a new biological function for the integrin avb3: initiation of fibronectin matrix assembly. Cell Adhes. Commun. 4, 149-158.
48. Wu, C., Kevins, V., O'Toole, T.E., McDonald, J.A., and Ginsberg, M.H. (1995). Integrin activation and cytoskeletal interaction are critical steps in the assembly of a fibronectin matrix. Cell 83, 715-724.
49. Yamada, K.M., and Miyamoto, S. (1995). Integrin transmembrane signaling and cytoskeletal control. Curr. Opin. Cell Biol. 7, 681-689.
50. Yamada, K.M., Yamada, S.S., and Pastan, I. (1976). Cell surface protein partially restores morphology, adhesiveness, and contact inhibition of movement to transformed fibroblasts. Proc. Natl. Acad. Sci. USA 73, 1271-1221.
51. Yang, J.T., Rayburn, H., and Hynes, R.O. (1993). Embryonic mesodermal defects in α5 integrin-deficient mice. Development 119, 1093-1105.
52. Yang, J.T., and Hynes, R.O. (1996). Fibronectin receptor functions in embryonic cells deficient in α5β1 integrin can be replaced by αv integrins. Mol. Biol. Cell 7, 1737-1748.