L-carnosine inhibits high-glucose-mediated matrix accumulation in human mesangial cells by interfering with TGF-β production and signalling

Nephrology Dialysis Transplantation

Volumn 26, Issue 12, 2011, Pages 3852-3858

  Köppel, Hannes ^a   Riedl, Eva ^a   Braunagel, Margarita ^a   Sauerhoefer, Sibylle ^a   Ehnert, Sabrina ^a   Godoy, Patricio ^a   Sternik, Paula ^a   Dooley, Steven ^a   Yard, Benito A ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

carnosine; diabetic nephropathy; fibrosis; mesangial matrix; TGF

Indexed keywords

CARNOSINE; COLLAGEN TYPE 6; FIBRONECTIN; GLUCOSE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MESSENGER RNA; SMAD1 PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE PRODUCTION; DRUG MECHANISM; EXTRACELLULAR MATRIX; GENE EXPRESSION; HUMAN; HUMAN CELL; HYPERGLYCEMIA; INHIBITION KINETICS; MESANGIUM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITION; SIGNAL TRANSDUCTION;

CARNOSINE; CELLS, CULTURED; EXTRACELLULAR MATRIX; GLUCOSE; HUMANS; MESANGIAL CELLS; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 82255185487     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfr324     Document Type: Article

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