Butyrate esterified to starch is released in the human gastrointestinal tract

American Journal of Clinical Nutrition

Volumn 94, Issue 5, 2011, Pages 1276-1283

  Clarke, Julie M ^a   Topping, David L ^a   Christophersen, Claus T ^a   Bird, Anthony R ^a   Lange, Kylie ^b   Saunders, Ian ^a   Cobiac, Lynne ^a  

^a CSIRO   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BUTYRIC ACID; STARCH;

ADULT; AGED; ARTICLE; COLON; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIETARY INTAKE; DIGESTION; ESTERIFICATION; FECES ANALYSIS; FEMALE; GASTROINTESTINAL TRACT; GRAM NEGATIVE BACTERIUM; HUMAN; MALE; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; MOLECULAR MICROBIOLOGY; NORMAL HUMAN; PARABACTEROIDES DISTASONIS; RANDOMIZED CONTROLLED TRIAL;

ADULT; AGED; AMYLOSE; BUTYRATES; CROSS-OVER STUDIES; DIET; DNA, BACTERIAL; FATTY ACIDS, VOLATILE; FECES; FEMALE; GASTROINTESTINAL TRACT; HUMANS; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; QUALITY OF LIFE; QUESTIONNAIRES; RNA, RIBOSOMAL, 16S; SINGLE-BLIND METHOD; STARCH; YOUNG ADULT; ZEA MAYS;

ZEA MAYS;

EID: 80055023996     PISSN: 00029165     EISSN: 19383207     Source Type: Journal    
DOI: 10.3945/ajcn.111.017228     Document Type: Article

References (51)

1. Mortensen FV, Hessov I, Birke H, Korsgaard N, Nielsen H. Microcirculatory and trophic effects of short chain fatty acids in the human rectum after Hartmann's procedure. Br J Surg 1991;78:1208-11.
2. Binder HJ. Role of colonic short-chain fatty acid transport in diarrhea. Annu Rev Physiol 2010;72:297-313.
3. Van Immerseel F, Russell JB, Flythe MD, Gantois I, Timbermont L, Pasmans F, Haesebrouck F, Ducatelle R. The use of organic acids to combat Salmonella in poultry: a mechanistic explanation of the efficacy. Avian Pathol 2006;35:182-8. (Pubitemid 43869824)
4. Bajka BH, Clarke JM, Topping DL, Cobiac L, Abeywardena MY, Patten GS. Butyrylated starch increases large bowel butyrate levels and lowers colonic smooth muscle contractility in rats. Nutr Res 2010;30:427-34.
5. Topping DL, Clifton PM. Short-chain fatty acids and human colonic function: roles of resistant starch and nonstarch polysaccharides. Physiol Rev 2001;81:1031-64. (Pubitemid 32611227)
6. Roediger WE. Utilization of nutrients by isolated epithelial cells of the rat colon. Gastroenterology 1982;83:424-9. (Pubitemid 12078229)
7. Cummings JH, Beatty ER, Kingman SM, Bingham SA, Englyst HN. Digestion and physiological properties of resistant starch in the human large bowel. Br J Nutr 1996;75:733-47. (Pubitemid 26000983)
8. van Munster IP, Tangerman A, Nagengast FM. Effect of resistant starch on colonic fermentation, bile acid metabolism, and mucosal proliferation. Dig Dis Sci 1994;39:834-42. (Pubitemid 24141790)
9. Phillips J, Muir JG, Birkett A, Lu ZX, Jones GP, O'Dea K, Young GP. Effect of resistant starch on fecal bulk and fermentation-dependent events in humans. Am J Clin Nutr 1995;62:121-30.
10. Noakes M, Clifton PM, Nestel PJ, Le Leu R, McIntosh G. Effect of high-amylose starch and oat bran on metabolic variables and bowel function in subjects with hypertriglyceridemia. Am J Clin Nutr 1996;64:944-51. (Pubitemid 26392883)
11. Thomas DJ, Atwell WA. Starches: practical guides for the food industry. St Paul, MN: Eagan Press, 1999.
12. Clarke JM, Bird AR, Topping DL, Cobiac L. Excretion of starch and esterified short chain fatty acids by ileostomists after the ingestion of acylated starches. Am J Clin Nutr 2007;86:1146-51. (Pubitemid 47538320)
13. Annison G, Illman RJ, Topping DL. Acetylated, propionylated or butyrylated starches raise large bowel short-chain fatty acids preferentially when fed to rats. J Nutr 2003;133:3523-8. (Pubitemid 37409482)
14. Bajka BH, Clarke JM, Cobiac L, Topping DL. Butyrylated starch protects colonocyte DNA against dietary protein-induced damage in rats. Carcinogenesis 2008;29:2169-74.
15. Clarke JM, Topping DL, Bird AR, Young GP, Cobiac L. Effects of high amylose maize starch and butyrylated high amylose maize starch on azoxymethane-induced intestinal cancer in rats. Carcinogenesis 2008;29:2190-4.
16. McOrist AL, Abell GCJ, Cooke C, Nyland K. Bacterial population dynamics and faecal short-chain fatty acid (SCFA) concentrations in healthy humans. Br J Nutr 2008;100:138-46.
17. Vonk RJ, Hagedoorn RE, de Graaff, Elzinga H, Tabak S, Yang YX, Stellaard F. Digestion of so-called resistant starch sources in the human small intestine. Am J Clin Nutr 2000;72:432-8. (Pubitemid 30620649)
18. Eypasch E, Williams JI, Wooddauphinee S, Ure BM, Schmulling C, Neugebauer E, Troidl H. Gastrointestinal quality-of-life index - development, validation and application of a new instrument. Br J Surg 1995;82:216-22.
19. Bajka BH, Topping DL, Cobiac L, Clarke JM. Butyrylated starch is less susceptible to enzymic hydrolysis and increases large-bowel butyrate more than high-amylose maize starch in the rat. Br J Nutr 2006;96:276-82. (Pubitemid 46470095)
20. Champ M. Determination of resistant starch in foods and food products: interlaboratory study. Eur J Clin Nutr 1992;46(suppl 2):S51-62.
21. King RA, May BL, Davies DA, Bird AR. Measurement of phenol and p-cresol in urine and feces using vacuum microdistillation and high-performance liquid chromatography. Anal Biochem 2009;384:27-33.
22. Yu Z, Morrison M. Improved extraction of PCR-quality community DNA from digesta and fecal samples. Biotechniques 2004;36:808-12. (Pubitemid 38620199)
23. Abell GCJ, Cooke CM, Bennett CN, Conlon MA, McOrist AL. Phylotypes related to Ruminococcus bromii are abundant in the large bowel of humans and increase in response to a diet high in resistant starch. FEMS Microbiol Ecol 2008;66:505-15.
24. Shannon CE, Weaver W. The mathematical theory of communication. Urbana, IL: University of Illinois Press, 1949.
25. Denman SE, McSweeney CS. Development of a real-time PCR assay for monitoring anaerobic fungal and cellulolytic bacterial populations within the rumen. FEMS Microbiol Ecol 2006;58:572-82. (Pubitemid 44748164)
26. Liu C, Song Y, McTeague M, Vu AW, Wexler H, Finegold SM. Rapid identification of the species of the Bacteroides fragilis group by multiplex PCR assays using group- and species-specific primers. FEMS Microbiol Lett 2003;222:9-16. (Pubitemid 36577346)
27. Wang RF, Cao WW, Cerniglia CE. Phylogenetic analysis of Fusobacterium prausnitzii based upon the 16S rRNA gene sequence and PCR confirmation. Int J Syst Bacteriol 1996;46:341-3. (Pubitemid 26030512)
28. Christophersen CT, Morrison M, Conlon MA. Overestimation of the abundance of sulfate-reducing bacteria in human feces by quantitative PCR targeting the Desulfovibrio 16S rRNA gene. Appl Environ Microbiol 2011;77:3544-6.
29. Rinttilä T, Kassinen A, Malinen E, Krogius L, Palva A. Development of an extensive set of 16S rDNA-targeted primers for quantification of pathogenic and indigenous bacteria in faecal samples by real-time PCR. J Appl Microbiol 2004;97:1166-77. (Pubitemid 39573940)
30. Collado MC, Derrien M, Isolauri E, de Vos WM, Salminen S. Intestinal integrity and Akkermansia muciniphila, a mucin-degrading member of the intestinal microbiota present in infants, adults, and the elderly. Appl Environ Microbiol 2007;73:7767-70.
31. Vandesompele J, De PK, Pattyn F, Poppe B, Van Roy N, De Paepe A, Speleman F. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 2002;3: RESEARCH0034.
32. Hellemans J, Mortier G, De PA, Speleman F, Vandesompele J. qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data. Genome Biol 2007;8:R19.
33. GraphPad Software. Grubb's test for detecting outliers. 2010. Available from: www graphpad com/quickcalcs/GrubbsHowTo cfm (cited 5 November 2010).
34. Cummings JH. The large intestine in nutrition and disease. Brussels, Belgium: Institut Danone, 1997:43-65.
35. J Abell GC, Christophersen C, McOrist AL, Clarke JM. Dietary resistant and butyrylated starches have different effects on the faecal bacterial flora of azoxymethane-treated rats. Br J Nutr 2011;105:1480-5.
36. Flint HJ, Stewart CS. Bacteroides and Prevotella. In: Richard K Robinson, Carl A Batt, Pradip D Patel, eds. Encyclopedia of food microbiology. San Diego, CA: Academic Press, 2000:198-203.
37. Sakamoto M, Benno Y. Reclassification of Bacteroides distasonis, Bacteroides goldsteinii and Bacteroides merdae as Parabacteroides distasonis gen. nov., comb. nov., Parabacteroides goldsteinii comb. nov. and Parabacteroides merdae comb. nov. Int J Syst Evol Microbiol 2006;56:1599-605. (Pubitemid 44109066)
38. Weaver GA, Krause JA, Miller TL, Wolin MJ. Cornstarch fermentation by the colonic microbial community yields more butyrate than does cabbage fiber fermentation; cornstarch fermentation rates correlate negatively with methanogenesis. Am J Clin Nutr 1992;55:70-7.
39. McOrist AL, Miller RB, Bird AR, Keogh JB, Noakes M, Topping DL, Conlon MA. Fecal butyrate levels vary widely among individuals but are usually increased by a diet high in resistant starch. J Nutr 2011;141:883-9.
40. Young GP, Le Leu RK. Resistant starch and colorectal neoplasia. J AOAC Int 2004;87:775-86.
41. Symonds EL, Kritas S, Omari TI, Butler RN. A combined 13CO2/H2 breath test can be used to assess starch digestion and fermentation in humans. J Nutr 2004;134:1193-6. (Pubitemid 38619961)
42. Mitchell BL, Lawson MJ, Davies M, Kerr Grant A, Roediger WEW, Illman RJ, Topping DL. Volatile fatty acids in the human intestine: studies in surgical patients. Nutr Res 1985;5:1089-92. (Pubitemid 16174898)
43. Cats A, de Vries EG, Mulder NH, Kleibeuker JH. Regional differences of physiological functions and cancer susceptibility in the human large intestine. Int J Oncol 1996;9:1055-69. (Pubitemid 26356452)
44. Le Leu RK, Brown IL, Hu Y, Esterman A, Young GP. Suppression of azoxymethane-induced colon cancer development in rats by dietary resistant starch. Cancer Biol Ther 2007;6:1621-6. (Pubitemid 351590335)
45. Le Leu RK, Brown IL, Hu Y, Morita T, Esterman A, Young GP. Effect of dietary resistant starch and protein on colonic fermentation and intestinal tumourigenesis in rats. Carcinogenesis 2007;28:240-5. (Pubitemid 46321839)
46. Toden S, Bird AR, Topping DL, Conlon MA. High red meat diets induce greater numbers of colonic dna double-strand breaks than white meat in rats: attenuation by high amylose maize starch. Carcinogenesis 2007;28:2355-62. (Pubitemid 350111594)
47. Burn J, Bishop DT, Mecklin JP, Macrae F, Moslein G, Olschwang S, Bisgaard ML, Ramesar R, Eccles D, Maher ER, et al. Effect of aspirin or resistant starch on colorectal neoplasia in the Lynch Syndrome. N Engl J Med 2008;359:2567-78.
48. Topping DL, Bird AR, Young GP. Effect of aspirin or resistant starch on colorectal neoplasia in the Lynch syndrome. N Engl J Med 2009;360:1462-3.
49. Bingham SA. Meat, starch, and nonstarch polysaccharides and large bowel cancer. Am J Clin Nutr 1988;48:762-7.
50. Toden S, Bird AR, Topping DL, Conlon MA. Resistant starch attenuates colonic DNA damage induced by higher dietary protein in rats. Nutr Cancer 2005;51:45-51. (Pubitemid 40365981)
51. Birkett A, Muir J, Phillips J, Jones G, O'Dea K. Resistant starch lowers fecal concentrations of ammonia and phenols in humans. Am J Clin Nutr 1996;63:766-72. (Pubitemid 26126598)