-
1
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel, D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116, 281-297 (2004).
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
2
-
-
0027751663
-
-
Lee, R.C., Feinbaum, R.L. & Ambros, V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75, 843-854 (1993).
-
Lee, R.C., Feinbaum, R.L. & Ambros, V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75, 843-854 (1993).
-
-
-
-
3
-
-
0037418839
-
bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila
-
Brennecke, J., Hipfner, D.R., Stark, A., Russell, R.B. & Cohen, S.M. bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila. Cell 113, 25-36 (2003).
-
(2003)
Cell
, vol.113
, pp. 25-36
-
-
Brennecke, J.1
Hipfner, D.R.2
Stark, A.3
Russell, R.B.4
Cohen, S.M.5
-
4
-
-
0346727524
-
MicroRNAs modulate hematopoietic lineage differentiation
-
Chen, C.Z., Li, L., Lodish, H.F. & Bartel, D.P. MicroRNAs modulate hematopoietic lineage differentiation. Science 303, 83-86 (2004).
-
(2004)
Science
, vol.303
, pp. 83-86
-
-
Chen, C.Z.1
Li, L.2
Lodish, H.F.3
Bartel, D.P.4
-
5
-
-
25444520537
-
miR-15 and miR-16 induce apoptosis by targeting BCL2
-
Cimmino, A. et al. miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc. Natl. Acad. Sci. USA 102, 13944-13949 (2005).
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 13944-13949
-
-
Cimmino, A.1
-
6
-
-
20044395613
-
RAS is regulated by the let-7 microRNA family
-
Johnson, S.M. et al. RAS is regulated by the let-7 microRNA family. Cell 120, 635-647 (2005).
-
(2005)
Cell
, vol.120
, pp. 635-647
-
-
Johnson, S.M.1
-
7
-
-
4644223259
-
Mechanisms of gene silencing by double-stranded RNA
-
Meister, G. & Tuschl, T. Mechanisms of gene silencing by double-stranded RNA. Nature 431, 343-349 (2004).
-
(2004)
Nature
, vol.431
, pp. 343-349
-
-
Meister, G.1
Tuschl, T.2
-
8
-
-
0035955374
-
Identification of novel genes coding for small expressed RNAs
-
Lagos-Quintana, M., Rauhut, R., Lendeckel, W. & Tuschl, T. Identification of novel genes coding for small expressed RNAs. Science 294, 853-858 (2001).
-
(2001)
Science
, vol.294
, pp. 853-858
-
-
Lagos-Quintana, M.1
Rauhut, R.2
Lendeckel, W.3
Tuschl, T.4
-
9
-
-
0035955361
-
An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
-
Lau, N.C., Lim, L.P., Weinstein, E.G. & Bartel, D.P. An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 294, 858-862 (2001).
-
(2001)
Science
, vol.294
, pp. 858-862
-
-
Lau, N.C.1
Lim, L.P.2
Weinstein, E.G.3
Bartel, D.P.4
-
10
-
-
0035955366
-
An extensive class of small RNAs in Caenorhabditis elegans
-
Lee, R.C. & Ambros, V. An extensive class of small RNAs in Caenorhabditis elegans. Science 294, 862-864 (2001).
-
(2001)
Science
, vol.294
, pp. 862-864
-
-
Lee, R.C.1
Ambros, V.2
-
11
-
-
20844463414
-
Identification of microRNAs of the herpesvirus family
-
Pfeffer, S. et al. Identification of microRNAs of the herpesvirus family. Nat. Methods 2, 269-276 (2005).
-
(2005)
Nat. Methods
, vol.2
, pp. 269-276
-
-
Pfeffer, S.1
-
12
-
-
33644750115
-
miRBase: MicroRNA sequences, targets and gene nomenclature
-
Griffiths-Jones, S., Grocock, R.J., van Dongen, S., Bateman, A. & Enright, A.J. miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 34, D140-D144 (2006).
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Griffiths-Jones, S.1
Grocock, R.J.2
van Dongen, S.3
Bateman, A.4
Enright, A.J.5
-
13
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
Lewis, B.P., Burge, C.B. & Bartel, D.P. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120, 15-20 (2005).
-
(2005)
Cell
, vol.120
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
14
-
-
0037009364
-
MicroRNA maturation: Stepwise processing and subcellular localization
-
Lee, Y., Jeon, K., Lee, J.T., Kim, S. & Kim, V.N. MicroRNA maturation: stepwise processing and subcellular localization. EMBO J. 21, 4663-4670 (2002).
-
(2002)
EMBO J
, vol.21
, pp. 4663-4670
-
-
Lee, Y.1
Jeon, K.2
Lee, J.T.3
Kim, S.4
Kim, V.N.5
-
15
-
-
18344369543
-
MicroRNA biogenesis: Coordinated cropping and dicing
-
Kim, V.N. MicroRNA biogenesis: coordinated cropping and dicing. Nat. Rev. Mol. Cell Biol. 6, 376-385 (2005).
-
(2005)
Nat. Rev. Mol. Cell Biol
, vol.6
, pp. 376-385
-
-
Kim, V.N.1
-
16
-
-
0347988235
-
Nuclear export of microRNA precursors
-
Lund, E., Guttinger, S., Calado, A., Dahlberg, J.E. & Kutay, U. Nuclear export of microRNA precursors. Science 303, 95-98 (2004).
-
(2004)
Science
, vol.303
, pp. 95-98
-
-
Lund, E.1
Guttinger, S.2
Calado, A.3
Dahlberg, J.E.4
Kutay, U.5
-
17
-
-
0347361541
-
Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
-
Yi, R., Qin, Y., Macara, I.G. & Cullen, B.R. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev. 17, 3011-3016 (2003).
-
(2003)
Genes Dev
, vol.17
, pp. 3011-3016
-
-
Yi, R.1
Qin, Y.2
Macara, I.G.3
Cullen, B.R.4
-
18
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing
-
Lee, Y. et al. The nuclear RNase III Drosha initiates microRNA processing. Nature 425, 415-419 (2003).
-
(2003)
Nature
, vol.425
, pp. 415-419
-
-
Lee, Y.1
-
19
-
-
9144224451
-
Processing of primary microRNAs by the Microprocessor complex
-
Denli, A.M., Tops, B.B., Plasterk, R.H., Ketting, R.F. & Hannon, G.J. Processing of primary microRNAs by the Microprocessor complex. Nature 432, 231-235 (2004).
-
(2004)
Nature
, vol.432
, pp. 231-235
-
-
Denli, A.M.1
Tops, B.B.2
Plasterk, R.H.3
Ketting, R.F.4
Hannon, G.J.5
-
20
-
-
9144225636
-
The Microprocessor complex mediates the genesis of microRNAs
-
Gregory, R.I. et al. The Microprocessor complex mediates the genesis of microRNAs. Nature 432, 235-240 (2004).
-
(2004)
Nature
, vol.432
, pp. 235-240
-
-
Gregory, R.I.1
-
21
-
-
10644234841
-
The Drosha-DGCR8 complex in primary microRNA processing
-
Han, J. et al. The Drosha-DGCR8 complex in primary microRNA processing. Genes Dev. 18, 3016-3027 (2004).
-
(2004)
Genes Dev
, vol.18
, pp. 3016-3027
-
-
Han, J.1
-
22
-
-
10344248903
-
The human DiGeorge syndrome critical region gene 8 and its D. melanogaster homolog are required for miRNA biogenesis
-
Landthaler, M., Yalcin, A. & Tuschl, T. The human DiGeorge syndrome critical region gene 8 and its D. melanogaster homolog are required for miRNA biogenesis. Curr. Biol. 14, 2162-2167 (2004).
-
(2004)
Curr. Biol
, vol.14
, pp. 2162-2167
-
-
Landthaler, M.1
Yalcin, A.2
Tuschl, T.3
-
23
-
-
33744520104
-
Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex
-
Han, J. et al. Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex. Cell 125, 887-901 (2006).
-
(2006)
Cell
, vol.125
, pp. 887-901
-
-
Han, J.1
-
24
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference
-
Bernstein, E., Caudy, A.A., Hammond, S.M. & Hannon, G.J. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409, 363-366 (2001).
-
(2001)
Nature
, vol.409
, pp. 363-366
-
-
Bernstein, E.1
Caudy, A.A.2
Hammond, S.M.3
Hannon, G.J.4
-
25
-
-
17844364875
-
Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing
-
Grishok, A. et al. Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell 106, 23-34 (2001).
-
(2001)
Cell
, vol.106
, pp. 23-34
-
-
Grishok, A.1
-
26
-
-
0035800521
-
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
-
Hutvagner, G. et al. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 293, 834-838 (2001).
-
(2001)
Science
, vol.293
, pp. 834-838
-
-
Hutvagner, G.1
-
27
-
-
0035887005
-
Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
-
Ketting, R.F. et al. Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev. 15, 2654-2659 (2001).
-
(2001)
Genes Dev
, vol.15
, pp. 2654-2659
-
-
Ketting, R.F.1
-
28
-
-
0035929322
-
A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans
-
Knight, S.W. & Bass, B.L. A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans. Science 293, 2269-2271 (2001).
-
(2001)
Science
, vol.293
, pp. 2269-2271
-
-
Knight, S.W.1
Bass, B.L.2
-
29
-
-
0034673638
-
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
-
Hammond, S.M., Bernstein, E., Beach, D. & Hannon, G.J. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature 404, 293-296 (2000).
-
(2000)
Nature
, vol.404
, pp. 293-296
-
-
Hammond, S.M.1
Bernstein, E.2
Beach, D.3
Hannon, G.J.4
-
30
-
-
27744537851
-
Human RISC couples microRNA biogenesis and posttranscriptional gene silencing
-
Gregory, R.I., Chendrimada, T.P., Cooch, N. & Shiekhattar, R. Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. Cell 123, 631-640 (2005).
-
(2005)
Cell
, vol.123
, pp. 631-640
-
-
Gregory, R.I.1
Chendrimada, T.P.2
Cooch, N.3
Shiekhattar, R.4
-
31
-
-
85064188091
-
Purification of brain nitric oxide synthase from baculovirus over-expression system and determination of cofactors
-
ed. Maines, M.D, Academic Press, San Diego
-
Mayer, B.J. et al. Purification of brain nitric oxide synthase from baculovirus over-expression system and determination of cofactors. in Nitric Oxide Synthase: Characterization and Functional Analysis (ed. Maines, M.D.) 130-139 (Academic Press, San Diego, 1996).
-
(1996)
Nitric Oxide Synthase: Characterization and Functional Analysis
, pp. 130-139
-
-
Mayer, B.J.1
-
32
-
-
0033511832
-
Cell biology of heme
-
Ponka, P. Cell biology of heme. Am. J. Med. Sci. 318, 241-256 (1999).
-
(1999)
Am. J. Med. Sci
, vol.318
, pp. 241-256
-
-
Ponka, P.1
-
33
-
-
0028984985
-
Delta-aminolevulinate increases heme saturation and yield of human cystathionine beta-synthase expressed in Escherichia coli
-
Kery, V., Elleder, D. & Kraus, J.P. Delta-aminolevulinate increases heme saturation and yield of human cystathionine beta-synthase expressed in Escherichia coli. Arch. Biochem. Biophys. 316, 24-29 (1995).
-
(1995)
Arch. Biochem. Biophys
, vol.316
, pp. 24-29
-
-
Kery, V.1
Elleder, D.2
Kraus, J.P.3
-
34
-
-
20444486424
-
Electrospray ionization mass spectrometry and ion mobility analysis of the 20S proteasome complex
-
Loo, J.A. et al. Electrospray ionization mass spectrometry and ion mobility analysis of the 20S proteasome complex. J. Am. Soc. Mass Spectrom. 16, 998-1008 (2005).
-
(2005)
J. Am. Soc. Mass Spectrom
, vol.16
, pp. 998-1008
-
-
Loo, J.A.1
-
35
-
-
33845281095
-
Cytochrome P-450 and chloroperoxidase: Thiolate-ligated heme enzymes. Spectroscopic determination of their active-site structures and mechanistic implications of thiolate ligation
-
Dawson, J.H. & Sono, M. Cytochrome P-450 and chloroperoxidase: thiolate-ligated heme enzymes. Spectroscopic determination of their active-site structures and mechanistic implications of thiolate ligation. Chem. Rev. 87, 1255-1276 (1987).
-
(1987)
Chem. Rev
, vol.87
, pp. 1255-1276
-
-
Dawson, J.H.1
Sono, M.2
-
36
-
-
0025615671
-
Arc repressor is tetrameric when bound to operator DNA
-
Brown, B.M., Bowie, J.U. & Sauer, R.T. Arc repressor is tetrameric when bound to operator DNA. Biochemistry 29, 11189-11195 (1990).
-
(1990)
Biochemistry
, vol.29
, pp. 11189-11195
-
-
Brown, B.M.1
Bowie, J.U.2
Sauer, R.T.3
-
37
-
-
0033001789
-
Crystal structures of c-Src reveal features of its autoinhibitory mechanism
-
Xu, W., Doshi, A., Lei, M., Eck, M.J. & Harrison, S.C. Crystal structures of c-Src reveal features of its autoinhibitory mechanism. Mol. Cell 3, 629-638 (1999).
-
(1999)
Mol. Cell
, vol.3
, pp. 629-638
-
-
Xu, W.1
Doshi, A.2
Lei, M.3
Eck, M.J.4
Harrison, S.C.5
-
38
-
-
0036441510
-
Autoinhibitory domains: Modular effectors of cellular regulation
-
Pufall, M.A. & Graves, B.J. Autoinhibitory domains: modular effectors of cellular regulation. Annu. Rev. Cell Dev. Biol. 18, 421-462 (2002).
-
(2002)
Annu. Rev. Cell Dev. Biol
, vol.18
, pp. 421-462
-
-
Pufall, M.A.1
Graves, B.J.2
-
39
-
-
0024852809
-
Trimerization of a yeast transcriptional activator via a coiled-coil motif
-
Sorger, P.K. & Nelson, H.C. Trimerization of a yeast transcriptional activator via a coiled-coil motif. Cell 59, 807-813 (1989).
-
(1989)
Cell
, vol.59
, pp. 807-813
-
-
Sorger, P.K.1
Nelson, H.C.2
-
40
-
-
8144225486
-
MicroRNA genes are transcribed by RNA polymerase II
-
Lee, Y. et al. MicroRNA genes are transcribed by RNA polymerase II. EMBO J. 23, 4051-4060 (2004).
-
(2004)
EMBO J
, vol.23
, pp. 4051-4060
-
-
Lee, Y.1
-
41
-
-
9344235449
-
Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs
-
Cai, X., Hagedorn, C.H. & Cullen, B.R. Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. RNA 10, 1957-1966 (2004).
-
(2004)
RNA
, vol.10
, pp. 1957-1966
-
-
Cai, X.1
Hagedorn, C.H.2
Cullen, B.R.3
-
42
-
-
6344281172
-
Identification of mammalian microRNA host genes and transcription units
-
Rodriguez, A., Griffiths-Jones, S., Ashurst, J.L. & Bradley, A. Identification of mammalian microRNA host genes and transcription units. Genome Res. 14, 1902-1910 (2004).
-
(2004)
Genome Res
, vol.14
, pp. 1902-1910
-
-
Rodriguez, A.1
Griffiths-Jones, S.2
Ashurst, J.L.3
Bradley, A.4
-
43
-
-
33747334621
-
Extensive post-transcriptional regulation of microRNAs and its implications for cancer
-
Thomson, J.M. et al. Extensive post-transcriptional regulation of microRNAs and its implications for cancer. Genes Dev. 20, 2202-2207 (2006).
-
(2006)
Genes Dev
, vol.20
, pp. 2202-2207
-
-
Thomson, J.M.1
-
44
-
-
3343024625
-
Reciprocal regulation of haem biosynthesis and the circadian clock in mammals
-
Kaasik, K. & Lee, C.C. Reciprocal regulation of haem biosynthesis and the circadian clock in mammals. Nature 430, 467-471 (2004).
-
(2004)
Nature
, vol.430
, pp. 467-471
-
-
Kaasik, K.1
Lee, C.C.2
-
45
-
-
14044251458
-
Human microRNA targets
-
John, B. et al. Human microRNA targets. PLoS Biol. 2, e363 (2004).
-
(2004)
PLoS Biol
, vol.2
-
-
John, B.1
-
46
-
-
10444268892
-
Heme-based sensors: Defining characteristics, recent developments, and regulatory hypotheses
-
Gilles-Gonzalez, M.A. & Gonzalez, G. Heme-based sensors: defining characteristics, recent developments, and regulatory hypotheses. J. Inorg. Biochem. 99, 1-22 (2005).
-
(2005)
J. Inorg. Biochem
, vol.99
, pp. 1-22
-
-
Gilles-Gonzalez, M.A.1
Gonzalez, G.2
-
47
-
-
0031890977
-
Acute porphyrias: Pathogenesis of neurological manifestations
-
Meyer, U.A., Schuurmans, M.M. & Lindberg, R.L. Acute porphyrias: pathogenesis of neurological manifestations. Semin. Liver Dis. 18, 43-52 (1998).
-
(1998)
Semin. Liver Dis
, vol.18
, pp. 43-52
-
-
Meyer, U.A.1
Schuurmans, M.M.2
Lindberg, R.L.3
-
48
-
-
0037069320
-
Heme deficiency may be a factor in the mitochondrial and neuronal decay of aging
-
Atamna, H., Killilea, D.W., Killilea, A.N. & Ames, B.N. Heme deficiency may be a factor in the mitochondrial and neuronal decay of aging. Proc. Natl. Acad. Sci. USA 99, 14807-14812 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 14807-14812
-
-
Atamna, H.1
Killilea, D.W.2
Killilea, A.N.3
Ames, B.N.4
-
49
-
-
3342880690
-
A role for heme in Alzheimer's disease: Heme binds amyloid beta and has altered metabolism
-
Atamna, H. & Frey, W.H., II. A role for heme in Alzheimer's disease: heme binds amyloid beta and has altered metabolism. Proc. Natl. Acad. Sci. USA 101, 11153-11158 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 11153-11158
-
-
Atamna, H.1
Frey II, W.H.2
-
50
-
-
4043072675
-
MicroRNAs act sequentially and asymmetrically to control chemosensory laterality in the nematode
-
Chang, S., Johnston, R.J., Jr., Frokjaer-Jensen, C., Lockery, S. & Hobert, O. MicroRNAs act sequentially and asymmetrically to control chemosensory laterality in the nematode. Nature 430, 785-789 (2004).
-
(2004)
Nature
, vol.430
, pp. 785-789
-
-
Chang, S.1
Johnston Jr., R.J.2
Frokjaer-Jensen, C.3
Lockery, S.4
Hobert, O.5
|