-
1
-
-
0019818758
-
Glucose intolerance and aging
-
DeFronzo RA. Glucose intolerance and aging. Diabetes Care. 1981; 4(4):493-501.
-
(1981)
Diabetes Care
, vol.4
, Issue.4
, pp. 493-501
-
-
Defronzo, R.A.1
-
2
-
-
0021813187
-
Homeostasis model assessment: Insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man
-
DOI 10.1007/BF00280883
-
Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentra-tions in man. Diabetologia. 1985;28(7):412-419. (Pubitemid 15018832)
-
(1985)
Diabetologia
, vol.28
, Issue.7
, pp. 412-419
-
-
Matthews, D.R.1
Hosker, J.P.2
Rudenski, A.S.3
-
3
-
-
0037237370
-
Glucose regulation and oxidative stress in healthy centenarians
-
DOI 10.1016/S0531-5565(02)00153-5, PII S0531556502001535
-
Barbieri M, Rizzo MR, Manzella D, et al. Glucose regulation and oxidative stress in healthy centenarians. Exp Gerontol. 2003;38(1-2): 137-143. (Pubitemid 36113262)
-
(2003)
Experimental Gerontology
, vol.38
, Issue.1-2
, pp. 137-143
-
-
Barbieri, M.1
Rizzo, M.R.2
Manzella, D.3
Grella, R.4
Ragno, E.5
Carbonella, M.6
Abbatecola, A.M.7
Paolisso, G.8
-
4
-
-
55849132493
-
Insulin and aging
-
Bartke A. Insulin and aging. Cell Cycle. 2008;7(21):3338-3343.
-
(2008)
Cell Cycle
, vol.7
, Issue.21
, pp. 3338-3343
-
-
Bartke, A.1
-
5
-
-
0037470501
-
The endocrine regulation of aging by insulin-like signals
-
DOI 10.1126/science.1081447
-
Tatar M, Bartke A, Antebi A. The endocrine regulation of aging by insulin-like signals. Science. 2003;299(5611):1346-1351. (Pubitemid 36254639)
-
(2003)
Science
, vol.299
, Issue.5611
, pp. 1346-1351
-
-
Tatar, M.1
Bartke, A.2
Antebi, A.3
-
6
-
-
0029952098
-
Dwarf mice and the ageing process
-
Brown-Borg HM, Borg KE, Meliska CJ, Bartke A. Dwarf mice and the ageing process. Nature. 1996;384(6604):33.
-
(1996)
Nature
, vol.384
, Issue.6604
, pp. 33
-
-
Brown-Borg, H.M.1
Borg, K.E.2
Meliska, C.J.3
Bartke, A.4
-
7
-
-
0036237480
-
Increased insulin sensitivity and upregulation of insulin receptor, insulin receptor substrate (IRS)-1 and IRS-2 in liver of Ames dwarf mice
-
DOI 10.1677/joe.0.1730081
-
Dominici FP, Hauck S, Argentino DP, Bartke A, Turyn D. Increased insulin sensitivity and upregulation of insulin receptor, insulin receptor substrate (IRS)-1 and IRS-2 in liver of Ames dwarf mice. J Endo-crinol. 2002;173(1):81-94. (Pubitemid 34428894)
-
(2002)
Journal of Endocrinology
, vol.173
, Issue.1
, pp. 81-94
-
-
Dominici, F.P.1
Hauck, S.2
Argentino, D.P.3
Bartke, A.4
Turyn, D.5
-
8
-
-
65549122452
-
Insulin sensitivity as a key mediator of growth hormone actions on longevity
-
Masternak MM, Panici JA, Bonkowski MS, Hughes LF, Bartke A. Insulin sensitivity as a key mediator of growth hormone actions on longevity. J Gerontol A Biol Sci Med Sci. 2009;64(5):516-521.
-
(2009)
J Gerontol A Biol Sci Med Sci
, vol.64
, Issue.5
, pp. 516-521
-
-
Masternak, M.M.1
Panici, J.A.2
Bonkowski, M.S.3
Hughes, L.F.4
Bartke, A.5
-
10
-
-
0031549576
-
Seminars in medicine of the Beth Israel Dea-coness Medical Center. Caloric intake and aging
-
Weindruch R, Sohal RS. Seminars in medicine of the Beth Israel Dea-coness Medical Center. Caloric intake and aging. N Engl J Med 1997;337(14):986-994.
-
(1997)
N Engl J Med
, vol.337
, Issue.14
, pp. 986-994
-
-
Weindruch, R.1
Sohal, R.S.2
-
11
-
-
0035936147
-
Extending the lifespan of long-lived mice
-
DOI 10.1038/35106646
-
Bartke A, Wright JC, Mattison JA, Ingram DK, Miller RA, Roth G S Extending the lifespan of long-lived mice. Nature. 2001;414(6862):412. (Pubitemid 34173717)
-
(2001)
Nature
, vol.414
, Issue.6862
, pp. 412
-
-
Bartke, A.1
Wright, J.C.2
Mattison, J.A.3
Ingram, D.K.4
Miller, R.A.5
Roth, G.S.6
-
12
-
-
0034455827
-
Assessment of growth parameters and life span of GHR/BP gene-disrupted mice
-
DOI 10.1210/en.141.7.2608
-
Coschigano KT, Clemmons D, Bellush LL, Kopchick JJ. Assessment of growth parameters and life span of GHR/BP gene-disrupted mice. Endocrinology. 2000;141(7):2608-2613. (Pubitemid 32269083)
-
(2000)
Endocrinology
, vol.141
, Issue.7
, pp. 2608-2613
-
-
Coschigano, K.T.1
Clemmons, D.2
Bellush, L.L.3
Kopchick, J.J.4
-
13
-
-
0041419437
-
Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span
-
DOI 10.1210/en.2003-0374
-
Coschigano KT, Holland AN, Riders ME, List EO, Flyvbjerg A, Kopchick JJ. Deletion, but not antagonism, of the mouse growth hor-mone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span. Endocrinol-ogy. 2003;144(9):3799-3810. (Pubitemid 37088732)
-
(2003)
Endocrinology
, vol.144
, Issue.9
, pp. 3799-3810
-
-
Coschigano, K.T.1
Holland, A.N.2
Riders, M.E.3
List, E.O.4
Flyvbjerg, A.5
Kopchick, J.J.6
-
14
-
-
0036086818
-
Life span extension by reduction in growth hormone-insulin-like growth factor-1 axis in a transgenic rat model
-
Shimokawa I, Higami Y, Utsuyama M, et al. Life span extension by reduction in growth hormone-insulin-like growth factor-1 axis in a transgenic rat model. Am J Pathol. 2002;160(6):2259-2265. (Pubitemid 34663416)
-
(2002)
American Journal of Pathology
, vol.160
, Issue.6
, pp. 2259-2265
-
-
Shimokawa, I.1
Higami, Y.2
Utsuyama, M.3
Tuchiya, T.4
Komatsu, T.5
Chiba, T.6
Yamaza, H.7
-
15
-
-
58049121301
-
Longevity genes: In-sights from calorie restriction and genetic longevity models
-
Shimokawa I, Chiba T, Yamaza H, Komatsu T. Longevity genes: in-sights from calorie restriction and genetic longevity models. Mol Cells. 2008;26(5):427-435.
-
(2008)
Mol Cells
, vol.26
, Issue.5
, pp. 427-435
-
-
Shimokawa, I.1
Chiba, T.2
Yamaza, H.3
Komatsu, T.4
-
16
-
-
0036233996
-
Models of growth hormone and IGF-1 defi ciency: Applications to studies of aging processes and life-span determination
-
Carter CS, Ramsey MM, Ingram RL, et al. Models of growth hormone and IGF-1 defi ciency: applications to studies of aging processes and life-span determination. J Gerontol A Biol Sci Med Sci. 2002;57(5): B177-B188.
-
(2002)
J Gerontol A Biol Sci Med Sci
, vol.57
, Issue.5
-
-
Carter, C.S.1
Ramsey, M.M.2
Ingram, R.L.3
-
17
-
-
27644584615
-
Influence of estrogen administration on the growth response to growth hormone (GH) in GH-deficient mice
-
Fintini D, Alba M, Salvatori R. Infl uence of estrogen administration on the growth response to growth hormone (GH) in GH-defi cient mice. Exp Biol Med (Maywood). 2005;230(10):715-720. (Pubitemid 41565940)
-
(2005)
Experimental Biology and Medicine
, vol.230
, Issue.10
, pp. 715-720
-
-
Fintini, D.1
Alba, M.2
Salvatori, R.3
-
18
-
-
13444249466
-
Hormone-treated Snell dwarf mice regain fertility but remain long lived and disease resistant
-
Vergara M, Smith-Wheelock M, Harper JM, Sigler R, Miller RA. Hormone-treated snell dwarf mice regain fertility but remain long lived and disease resistant. J Gerontol A Biol Sci Med Sci. 2004; 59(12):1244-1250. (Pubitemid 40209410)
-
(2004)
Journals of Gerontology - Series A Biological Sciences and Medical Sciences
, vol.59
, Issue.12
, pp. 1244-1250
-
-
Vergara, M.1
Smith-Wheelock, M.2
Harper, J.M.3
Sigler, R.4
Miller, R.A.5
-
19
-
-
12344335482
-
Long-lived growth hormone receptor knockout mice: Interaction of reduced insulin-like growth factor I/insulin signaling and caloric restriction
-
DOI 10.1210/en.2004-1120
-
Al-Regaiey KA, Masternak MM, Bonkowski M, Sun L, Bartke A. Long-lived growth hormone receptor knockout mice: interaction of reduced insulin-like growth factor i/insulin signaling and caloric re-striction. Endocrinology. 2005;146(2):851-860. (Pubitemid 40129843)
-
(2005)
Endocrinology
, vol.146
, Issue.2
, pp. 851-860
-
-
Al-Regaiey, K.A.1
Masternak, M.M.2
Bonkowski, M.3
Sun, L.4
Bartke, A.5
-
20
-
-
20244372225
-
Growth hormone and sex steroid administration in healthy aged women and men: A randomized controlled trial
-
DOI 10.1001/jama.288.18.2282
-
Blackman MR, Sorkin JD, Munzer T, et al. Growth hormone and sex steroid administration in healthy aged women and men: a randomized controlled trial. JAMA. 2002;288(18):2282-2292. (Pubitemid 35291758)
-
(2002)
Journal of the American Medical Association
, vol.288
, Issue.18
, pp. 2282-2292
-
-
Blackman, M.R.1
Sorkin, J.D.2
Munzer, T.3
Bellantoni, M.F.4
Busby-Whitehead, J.5
Stevens, T.E.6
Jayme, J.7
O'Connor, K.G.8
Christmas, C.9
Tobin, J.D.10
Stewart, K.J.11
Cottrell, E.12
Clair, C.St.13
Pabst, K.M.14
Harman, S.M.15
-
21
-
-
0036145971
-
High-dose growth hormone (GH) treatment in non-GH-deficient children born small for gestational age induces growth responses related to pre-treatment GH secretion and associated with a reversible decrease in insulin sensitivity
-
DOI 10.1210/jc.87.1.148
-
de ZF, Ong K, van HM, Mohn A, Woods K, Dunger D. High-dose growth hormone (GH) treatment in non-GH-defi cient children born small for gestational age induces growth responses related to pretreat-ment GH secretion and associated with a reversible decrease in insulin sensitivity. J Clin Endocrinol Metab. 2002;87(1):148-151. (Pubitemid 34084684)
-
(2002)
Journal of Clinical Endocrinology and Metabolism
, vol.87
, Issue.1
, pp. 148-151
-
-
De Zegher, F.1
Ong, K.2
Van Helvoirt, M.3
Mohn, A.4
Woods, K.5
Dunger, D.6
-
22
-
-
0141504382
-
Effects of GH on urea, glucose and lipid metabolism, and insulin sensitivity during fasting in GH-deficient patients
-
Norrelund H, Djurhuus C, Jorgensen JO, et al. Effects of GH on urea, glucose and lipid metabolism, and insulin sensitivity during fasting in GH-deficient patients. Am J Physiol Endocrinol Metab. 2003;285(4): E737-E743. (Pubitemid 37176424)
-
(2003)
American Journal of Physiology - Endocrinology and Metabolism
, vol.285
, Issue.4
-
-
Norrelund, H.1
Djurhuus, C.2
Jorgensen, J.O.L.3
Nielsen, So.4
Nair, K.S.5
Schmitz, O.6
Christiansen, J.S.7
Moller, N.8
-
23
-
-
47049090142
-
Adiponectin levels and geno-type: A potential regulator of life span in humans
-
Atzmon G, Pollin TI, Crandall J, et al. Adiponectin levels and geno-type: a potential regulator of life span in humans. J Gerontol A Biol Sci Med Sci. 2008;63(5):447-453.
-
(2008)
J Gerontol A Biol Sci Med Sci
, vol.63
, Issue.5
, pp. 447-453
-
-
Atzmon, G.1
Pollin, T.I.2
Crandall, J.3
-
24
-
-
8744234072
-
Serum adiponectin is reduced in acromegaly and normalized after correction of growth hormone excess
-
DOI 10.1210/jc.2003-032023
-
Lam KS, Xu A, Tan KC, Wong LC, Tiu SC, Tam S. Serum adiponectin is reduced in acromegaly and normalized after correction of growth hormone excess. J Clin Endocrinol Metab. 2004;89(11):5448-5453. (Pubitemid 39518424)
-
(2004)
Journal of Clinical Endocrinology and Metabolism
, vol.89
, Issue.11
, pp. 5448-5453
-
-
Lam, K.S.-L.1
Xu, A.2
Tan, K.C.-B.3
Wong, L.-C.4
Tiu, S.-C.5
Tam, S.6
-
25
-
-
0026681367
-
Down regu-lation of masked and unmasked insulin receptors in the liver of trans-genic mice expressing bovine growth hormone gene
-
Balbis A, Dellacha JM, Calandra RS, Bartke A, Turyn D. Down regu-lation of masked and unmasked insulin receptors in the liver of trans-genic mice expressing bovine growth hormone gene. Life Sci. 1992; 51(10):771-778.
-
(1992)
Life Sci
, vol.51
, Issue.10
, pp. 771-778
-
-
Balbis, A.1
Dellacha, J.M.2
Calandra, R.S.3
Bartke, A.4
Turyn, D.5
-
26
-
-
0030582463
-
Overexpression of bovine growth hormone in transgenic mice is associated with changes in hepatic insulin receptors and in their kinase activity
-
DOI 10.1016/0024-3205(96)00462-6
-
Balbis A, Bartke A, Turyn D. Overexpression of bovine growth hormone in transgenic mice is associated with changes in hepatic insulin receptors and in their kinase activity. Life Sci. 1996;59(16): 1363-1371. (Pubitemid 26344589)
-
(1996)
Life Sciences
, vol.59
, Issue.16
, pp. 1363-1371
-
-
Balbis, A.1
Bartke, A.2
Turyn, D.3
-
27
-
-
0032883443
-
Alterations in the early steps of the insulin-signaling system in skeletal muscle of GH-transgenic mice
-
Dominici FP, Cifone D, Bartke A, Turyn D. Alterations in the early steps of the insulin-signaling system in skeletal muscle of GH-transgenic mice. Am J Physiol. 1999;277(3, pt 1):E447-E454. (Pubitemid 29458204)
-
(1999)
American Journal of Physiology - Endocrinology and Metabolism
, vol.277
, Issue.3
-
-
Dominici, F.P.1
Cifone, D.2
Bartke, A.3
Turyn, D.4
-
28
-
-
0020532857
-
Hepatocyte insulin binding and action in rats with sommatomammotrophic tumours
-
Davidson MB, Melmed S. Hepatocyte insulin binding and action in rats with somatomammotrophic tumours. Diabetologia. 1983;25(1): 60-65. (Pubitemid 13070131)
-
(1983)
Diabetologia
, vol.25
, Issue.1
, pp. 60-65
-
-
Davidson, M.B.1
Melmed, S.2
-
29
-
-
0036521760
-
Growth hormone-induced alterations in the insulin-signaling system
-
Dominici FP, Turyn D. Growth hormone-induced alterations in the insulin-signaling system. Exp Biol Med (Maywood). 2002 ; 227 (3): 149-157.
-
(2002)
Exp Biol Med (Maywood)
, vol.227
, Issue.3
, pp. 149-157
-
-
Dominici, F.P.1
Turyn, D.2
-
30
-
-
84887212549
-
Disruption of growth hormone receptor prevents calorie restriction from improving insulin action and longevity
-
Bonkowski MS, Dominici FP, Arum O, et al. Disruption of growth hormone receptor prevents calorie restriction from improving insulin action and longevity. PLoS One. 2009;4(2):e4567.
-
(2009)
PLoS One
, vol.4
, Issue.2
-
-
Bonkowski, M.S.1
Dominici, F.P.2
Arum, O.3
-
31
-
-
18244379033
-
Evidence for down-regulation of phosphoinositide 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR)-dependent translation regulatory signaling pathways in Ames dwarf mice
-
Sharp ZD, Bartke A. Evidence for down-regulation of phosphoinosit-ide 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR)-dependent translation regulatory signaling pathways in Ames dwarf mice. J Gerontol A Biol Sci Med Sci. 2005;60(3):293-300. (Pubitemid 40628792)
-
(2005)
Journals of Gerontology - Series A Biological Sciences and Medical Sciences
, vol.60
, Issue.3
, pp. 293-300
-
-
Sharp, Z.D.1
Bartke, A.2
-
32
-
-
70350435108
-
Is altered expression of hepatic insulin-related genes in growth hormone receptor knockout mice due to GH resistance or a difference in biological life spans?
-
Panici JA, Wang F, Bonkowski MS, et al. Is altered expression of hepatic insulin-related genes in growth hormone receptor knockout mice due to GH resistance or a difference in biological life spans? J Gerontol A Biol Sci Med Sci. 2009;64A:1126-1133.
-
(2009)
J Gerontol A Biol Sci Med Sci
, vol.64 A
, pp. 1126-1133
-
-
Panici, J.A.1
Wang, F.2
Bonkowski, M.S.3
-
33
-
-
67650944993
-
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
-
Harrison DE, Strong R, Sharp ZD, et al. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature. 2009; 460(7253):392-395.
-
(2009)
Nature
, vol.460
, Issue.7253
, pp. 392-395
-
-
Harrison, D.E.1
Strong, R.2
Sharp, Z.D.3
|