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Volumn 51, Issue 2, 2014, Pages 191-200

A novel benzenediamine derivate rescued mice from experimental sepsis by attenuating proinflammatory mediators via IRAK4

Author keywords

FC 99; Inflammation; IRAK4; Macrophage; Sepsis

Indexed keywords

FC-99; INFLAMMATION; IRAK4; MACROPHAGE; SEPSIS;

EID: 84905496661     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2013-0411OC     Document Type: Article
Times cited : (19)

References (43)
  • 1
    • 0035936797 scopus 로고    scopus 로고
    • The tnf and tnf receptor superfamilies: Integrating mammalian biology
    • Locksley RM, Killeen N, Lenardo MJ. The tnf and tnf receptor superfamilies: integrating mammalian biology. Cell 2001;104:487-501.
    • (2001) Cell , vol.104 , pp. 487-501
    • Locksley, R.M.1    Killeen, N.2    Lenardo, M.J.3
  • 3
    • 39649083371 scopus 로고    scopus 로고
    • Inflammatory mechanisms: The molecular basis of inflammation and disease
    • Libby P. Inflammatory mechanisms: the molecular basis of inflammation and disease. Nutr Rev 2007;65:S140-S146.
    • (2007) Nutr Rev , vol.65
    • Libby, P.1
  • 4
    • 33644872836 scopus 로고    scopus 로고
    • Inflammation and cardiovascular disease mechanisms
    • Libby P. Inflammation and cardiovascular disease mechanisms. Am J Clin Nutr 2006;83:456S-460S.
    • (2006) Am J Clin Nutr , vol.83
    • Libby, P.1
  • 5
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens LM, Werb Z. Inflammation and cancer. Nature 2002;420:860-867.
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 7
    • 0037426726 scopus 로고    scopus 로고
    • The pathophysiology and treatment of sepsis
    • Hotchkiss RS, Karl IE. The pathophysiology and treatment of sepsis. N Engl J Med 2003;348:138-150.
    • (2003) N Engl J Med , vol.348 , pp. 138-150
    • Hotchkiss, R.S.1    Karl, I.E.2
  • 8
    • 0034882150 scopus 로고    scopus 로고
    • Endophytes: A rich source of functional metabolites
    • Tan RX, Zou WX. Endophytes: a rich source of functional metabolites. Nat Prod Rep 2001;18:448-459.
    • (2001) Nat Prod Rep , vol.18 , pp. 448-459
    • Tan, R.X.1    Zou, W.X.2
  • 10
    • 3042553356 scopus 로고    scopus 로고
    • Fumigaclavine c improves concanavalin a-induced liver injury in mice mainly via inhibiting tnf-α production and lymphocyte adhesion to extracellular matrices
    • Zhao Y, Liu J, Wang J, Wang L, Yin H, Tan R, Xu Q. Fumigaclavine c improves concanavalin a-induced liver injury in mice mainly via inhibiting tnf-α production and lymphocyte adhesion to extracellular matrices. J Pharm Pharmacol 2004;56:775-782.
    • (2004) J Pharm Pharmacol , vol.56 , pp. 775-782
    • Zhao, Y.1    Liu, J.2    Wang, J.3    Wang, L.4    Yin, H.5    Tan, R.6    Xu, Q.7
  • 11
    • 22044435268 scopus 로고    scopus 로고
    • Fumigaclavine c, an fungal metabolite, improves experimental colitis in mice via downregulating th1 cytokine production and matrix metalloproteinase activity
    • Wu X-F, Fei M-J, Shu R-G, Tan R-X, Xu Q. Fumigaclavine c, an fungal metabolite, improves experimental colitis in mice via downregulating th1 cytokine production and matrix metalloproteinase activity. Int Immunopharmacol 2005;5:1543-1553.
    • (2005) Int Immunopharmacol , vol.5 , pp. 1543-1553
    • Wu, X.-F.1    Fei, M.-J.2    Shu, R.-G.3    Tan, R.-X.4    Xu, Q.5
  • 14
    • 84888605980 scopus 로고    scopus 로고
    • Suppression of ptrf alleviates the polymicrobial sepsis induced by cecal ligation and puncture in mice
    • Zheng Y, Lee S, Liang X, Wei S, Moon HG, Jin Y. Suppression of ptrf alleviates the polymicrobial sepsis induced by cecal ligation and puncture in mice. J Infect Dis 2013;208:1803-1812.
    • (2013) J Infect Dis , vol.208 , pp. 1803-1812
    • Zheng, Y.1    Lee, S.2    Liang, X.3    Wei, S.4    Moon, H.G.5    Jin, Y.6
  • 15
    • 77951260924 scopus 로고    scopus 로고
    • The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors
    • Kawai T, Akira S. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 2010;11:373-384.
    • (2010) Nat Immunol , vol.11 , pp. 373-384
    • Kawai, T.1    Akira, S.2
  • 16
    • 32044439157 scopus 로고    scopus 로고
    • Pathobiology of sepsis: Are we still asking the same questions?
    • Baron RM, Baron MJ, Perrella MA. Pathobiology of sepsis: are we still asking the same questions? Am J Respir Cell Mol Biol 2006;34:129-134.
    • (2006) Am J Respir Cell Mol Biol , vol.34 , pp. 129-134
    • Baron, R.M.1    Baron, M.J.2    Perrella, M.A.3
  • 17
    • 0003633755 scopus 로고    scopus 로고
    • Washington, DC: National Academy Press;, accessed 2013 Sep. 28
    • Institute of Laboratory Animal Resources; Commission on Life Sciences; National Research Council. Guide for the care and use of laboratory animals. Washington, DC: National Academy Press; 1996 [accessed 2013 Sep. 28]. Available from: http://grants.Nih.Gov/grants/olaw/olaw.htm
    • (1996) Guide for the Care and use of Laboratory Animals
  • 18
    • 61449154547 scopus 로고    scopus 로고
    • Immunodesign of experimental sepsis by cecal ligation and puncture
    • Rittirsch D, Huber-Lang MS, Flierl MA, Ward PA. Immunodesign of experimental sepsis by cecal ligation and puncture. Nat Protoc 2009;4:31-36.
    • (2009) Nat Protoc , vol.4 , pp. 31-36
    • Rittirsch, D.1    Huber-Lang, M.S.2    Flierl, M.A.3    Ward, P.A.4
  • 21
    • 0036216769 scopus 로고    scopus 로고
    • Phagocytosis of microbes: Complexity in action
    • Underhill DM, Ozinsky A. Phagocytosis of microbes: complexity in action. Annu Rev Immunol 2002;20:825-852.
    • (2002) Annu Rev Immunol , vol.20 , pp. 825-852
    • Underhill, D.M.1    Ozinsky, A.2
  • 22
    • 0035104119 scopus 로고    scopus 로고
    • Lps induction of gene expression in human monocytes
    • Guha M, Mackman N. Lps induction of gene expression in human monocytes. Cell Signal 2001;13:85-94.
    • (2001) Cell Signal , vol.13 , pp. 85-94
    • Guha, M.1    Mackman, N.2
  • 23
    • 0035877718 scopus 로고    scopus 로고
    • Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex: Transfer from cd14 to tlr4 and md-2
    • da Silva Correia J, Soldau K, Christen U, Tobias PS, Ulevitch RJ. Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex: transfer from cd14 to tlr4 and md-2. J Biol Chem 2001;276:21129-21135.
    • (2001) J Biol Chem , vol.276 , pp. 21129-21135
    • Da Silva Correia, J.1    Soldau, K.2    Christen, U.3    Tobias, P.S.4    Ulevitch, R.J.5
  • 24
    • 0037292275 scopus 로고    scopus 로고
    • Functional diversity and regulation of different interleukin-1 receptor-associated kinase (irak) family members
    • Janssens S, Beyaert R. Functional diversity and regulation of different interleukin-1 receptor-associated kinase (irak) family members. Mol Cell 2003;11:293-302.
    • (2003) Mol Cell , vol.11 , pp. 293-302
    • Janssens, S.1    Beyaert, R.2
  • 26
    • 0038062839 scopus 로고    scopus 로고
    • Proinflammatory cytokines and sepsis syndrome: Not enough, or too much of a good thing?
    • Netea MG, van der Meer JW, van Deuren M, Kullberg BJ. Proinflammatory cytokines and sepsis syndrome: not enough, or too much of a good thing? Trends Immunol 2003;24:254-258.
    • (2003) Trends Immunol , vol.24 , pp. 254-258
    • Netea, M.G.1    Van Der Meer, J.W.2    Van Deuren, M.3    Kullberg, B.J.4
  • 27
  • 28
    • 33750537650 scopus 로고    scopus 로고
    • Endotoxin, tlr4 signaling and vascular inflammation: Potential therapeutic targets in cardiovascular disease
    • Stoll LL, Denning GM, Weintraub NL. Endotoxin, tlr4 signaling and vascular inflammation: potential therapeutic targets in cardiovascular disease. Curr Pharm Des 2006;12:4229-4245.
    • (2006) Curr Pharm des , vol.12 , pp. 4229-4245
    • Stoll, L.L.1    Denning, G.M.2    Weintraub, N.L.3
  • 29
    • 0030831210 scopus 로고    scopus 로고
    • A human homologue of the drosophila toll protein signals activation of adaptive immunity
    • Medzhitov R, Preston-Hurlburt P, Janeway CA Jr. A human homologue of the drosophila toll protein signals activation of adaptive immunity. Nature 1997;388:394-397.
    • (1997) Nature , vol.388 , pp. 394-397
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Janeway Jr., C.A.3
  • 30
    • 83255181885 scopus 로고    scopus 로고
    • Chaetoglobosin fex from the marine-derived endophytic fungus inhibits induction of inflammatory mediators via Toll-like receptor 4 signaling in macrophages
    • Dou H, Song Y, Liu X, Gong W, Li E, Tan R, Hou Y. Chaetoglobosin fex from the marine-derived endophytic fungus inhibits induction of inflammatory mediators via Toll-like receptor 4 signaling in macrophages. Biol Pharm Bull 2011;34:1864-1873.
    • (2011) Biol Pharm Bull , vol.34 , pp. 1864-1873
    • Dou, H.1    Song, Y.2    Liu, X.3    Gong, W.4    Li, E.5    Tan, R.6    Hou, Y.7
  • 31
    • 0002958069 scopus 로고    scopus 로고
    • Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state
    • Hume DA, Underhill DM, Sweet MJ, Ozinsky AO, Liew FY, Aderem A. Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state. BMC Immunol 2001;2:11.
    • (2001) BMC Immunol , vol.2 , pp. 11
    • Hume, D.A.1    Underhill, D.M.2    Sweet, M.J.3    Ozinsky, A.O.4    Liew, F.Y.5    Aderem, A.6
  • 36
    • 4644333526 scopus 로고    scopus 로고
    • The role of interleukin 1 receptor-associated kinase-4 (irak-4) kinase activity in irak-4-mediated signaling
    • Lye E, Mirtsos C, Suzuki N, Suzuki S, Yeh WC. The role of interleukin 1 receptor-associated kinase-4 (irak-4) kinase activity in irak-4-mediated signaling. J Biol Chem 2004;279:40653-40658.
    • (2004) J Biol Chem , vol.279 , pp. 40653-40658
    • Lye, E.1    Mirtsos, C.2    Suzuki, N.3    Suzuki, S.4    Yeh, W.C.5
  • 37
    • 0035910470 scopus 로고    scopus 로고
    • A novel synthetic acyclic lipid a-like agonist activates cells via the lipopolysaccharide/toll-like receptor 4 signaling pathway
    • Lien E, Chow JC, Hawkins LD, McGuinness PD, Miyake K, Espevik T, Gusovsky F, Golenbock DT. A novel synthetic acyclic lipid a-like agonist activates cells via the lipopolysaccharide/toll-like receptor 4 signaling pathway. J Biol Chem 2001;276:1873-1880.
    • (2001) J Biol Chem , vol.276 , pp. 1873-1880
    • Lien, E.1    Chow, J.C.2    Hawkins, L.D.3    McGuinness, P.D.4    Miyake, K.5    Espevik, T.6    Gusovsky, F.7    Golenbock, D.T.8
  • 38
    • 0029902763 scopus 로고    scopus 로고
    • Computational methods for biomolecular docking
    • Lengauer T, Rarey M. Computational methods for biomolecular docking. Curr Opin Struct Biol 1996;6:402-406.
    • (1996) Curr Opin Struct Biol , vol.6 , pp. 402-406
    • Lengauer, T.1    Rarey, M.2
  • 39
    • 0033996762 scopus 로고    scopus 로고
    • The i kappa b kinase (ikk) and nf-kappa b: Key elements of proinflammatory signalling
    • Karin M, Delhase M. The i kappa b kinase (ikk) and nf-kappa b: key elements of proinflammatory signalling. Semin Immunol 2000;12:85-98.
    • (2000) Semin Immunol , vol.12 , pp. 85-98
    • Karin, M.1    Delhase, M.2
  • 40
    • 0030615201 scopus 로고    scopus 로고
    • Nuclear factor-kappab: A pivotal transcription factor in chronic inflammatory diseases
    • Barnes PJ, Karin M. Nuclear factor-kappab: a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med 1997;336:1066-1071.
    • (1997) N Engl J Med , vol.336 , pp. 1066-1071
    • Barnes, P.J.1    Karin, M.2
  • 41
    • 0034175930 scopus 로고    scopus 로고
    • The ikk complex: An integrator of all signals that activate nfkappab?
    • Israel A. The ikk complex: an integrator of all signals that activate nfkappab? Trends Cell Biol 2000;10:129-133.
    • (2000) Trends Cell Biol , vol.10 , pp. 129-133
    • Israel, A.1
  • 42
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian map kinase signalling cascades
    • Chang L, Karin M. Mammalian map kinase signalling cascades. Nature 2001;410:37-40.
    • (2001) Nature , vol.410 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 43
    • 84871828778 scopus 로고    scopus 로고
    • Complete dependence on irak4 kinase activity in tlr2, but not tlr4, signaling pathways underlies decreased cytokine production and increased susceptibility to streptococcus pneumoniae infection in irak4 kinaseinactive mice
    • Pennini ME, Perkins DJ, Salazar AM, Lipsky M, Vogel SN. Complete dependence on irak4 kinase activity in tlr2, but not tlr4, signaling pathways underlies decreased cytokine production and increased susceptibility to streptococcus pneumoniae infection in irak4 kinaseinactive mice. J Immunol 2013;190:307-316.
    • (2013) J Immunol , vol.190 , pp. 307-316
    • Pennini, M.E.1    Perkins, D.J.2    Salazar, A.M.3    Lipsky, M.4    Vogel, S.N.5


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