-
1
-
-
0037129380
-
Nonalcoholic fatty liver disease
-
Angulo P. Nonalcoholic fatty liver disease. N Engl J Med. 2002;346(16):1221-1231.
-
(2002)
N Engl J Med.
, vol.346
, Issue.16
, pp. 1221-1231
-
-
Angulo, P.1
-
2
-
-
79959517565
-
Human fatty liver disease: Old questions and new insights
-
Cohen JC, Horton JD, Hobbs HH. Human fatty liver disease: old questions and new insights. Science. 2011;332(6037):1519-1523.
-
(2011)
Science
, vol.332
, Issue.6037
, pp. 1519-1523
-
-
Cohen, J.C.1
Horton, J.D.2
Hobbs, H.H.3
-
3
-
-
78651089694
-
Animal models of nonalcoholic fatty liver disease
-
Hebbard L, George J. Animal models of nonalcoholic fatty liver disease. Nat Rev Gastroenterol Hepatol. 2011;8(1):35-44.
-
(2011)
Nat Rev Gastroenterol Hepatol.
, vol.8
, Issue.1
, pp. 35-44
-
-
Hebbard, L.1
George, J.2
-
4
-
-
84878930738
-
Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis
-
Anstee QM, Targher G, Day CP. Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis. Nat Rev Gastroenterol Hepatol. 2013;10(6):330-344.
-
(2013)
Nat Rev Gastroenterol Hepatol.
, vol.10
, Issue.6
, pp. 330-344
-
-
Anstee, Q.M.1
Targher, G.2
Day, C.P.3
-
5
-
-
75449094816
-
Obesity and nonalcoholic fatty liver disease: Biochemical, metabolic, and clinical implications
-
Fabbrini E, Sullivan S, Klein S. Obesity and nonalcoholic fatty liver disease: biochemical, metabolic, and clinical implications. Hepatology. 2010;51(2):679-689.
-
(2010)
Hepatology
, vol.51
, Issue.2
, pp. 679-689
-
-
Fabbrini, E.1
Sullivan, S.2
Klein, S.3
-
6
-
-
28544447371
-
Periostin null mice exhibit dwarfism, incisor enamel defects, and an early-onset periodontal disease-like phenotype
-
Rios H, et al. Periostin null mice exhibit dwarfism, incisor enamel defects, and an early-onset periodontal disease-like phenotype. Mol Cell Biol. 2005;25(24):11131-11144.
-
(2005)
Mol Cell Biol.
, vol.25
, Issue.24
, pp. 11131-11144
-
-
Rios, H.1
-
7
-
-
84861722262
-
The multiple facets of periostin in bone metabolism
-
Merle B, Garnero P. The multiple facets of periostin in bone metabolism. Osteoporos Int. 2012;23(4):1199-1212.
-
(2012)
Osteoporos Int.
, vol.23
, Issue.4
, pp. 1199-1212
-
-
Merle, B.1
Garnero, P.2
-
8
-
-
11144357346
-
Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway
-
Bao S, et al. Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway. Cancer Cell. 2004;5(4):329-339.
-
(2004)
Cancer Cell.
, vol.5
, Issue.4
, pp. 329-339
-
-
Bao, S.1
-
9
-
-
33746895756
-
Periostin promotes invasion and anchorage-independent growth in the metastatic process of head and neck cancer
-
Kudo Y, et al. Periostin promotes invasion and anchorage-independent growth in the metastatic process of head and neck cancer. Cancer Res. 2006;66(14):6928-6935.
-
(2006)
Cancer Res.
, vol.66
, Issue.14
, pp. 6928-6935
-
-
Kudo, Y.1
-
10
-
-
77954371506
-
Periostin, a cell adhesion molecule, facilitates invasion in the tumor microenvironment and annotates a novel tumorinvasive signature in esophageal cancer
-
Michaylira CZ, et al. Periostin, a cell adhesion molecule, facilitates invasion in the tumor microenvironment and annotates a novel tumorinvasive signature in esophageal cancer. Cancer Res. 2010;70(13):5281-5292.
-
(2010)
Cancer Res.
, vol.70
, Issue.13
, pp. 5281-5292
-
-
Michaylira, C.Z.1
-
11
-
-
84855425160
-
Interactions between cancer stem cells and their niche govern metastatic colonization
-
Malanchi I, et al. Interactions between cancer stem cells and their niche govern metastatic colonization. Nature. 2011;481(7379):85-89.
-
(2011)
Nature
, vol.481
, Issue.7379
, pp. 85-89
-
-
Malanchi, I.1
-
12
-
-
67650451085
-
The multifaceted role of periostin in tumorigenesis
-
Ruan K, Bao S, Ouyang G. The multifaceted role of periostin in tumorigenesis. Cell Mol Life Sci. 2009;66(14):2219-2230.
-
(2009)
Cell Mol Life Sci.
, vol.66
, Issue.14
, pp. 2219-2230
-
-
Ruan, K.1
Bao, S.2
Ouyang, G.3
-
13
-
-
84889632658
-
Yin Yang 1 promotes hepatic steatosis through repression of farnesoid X receptor in obese mice
-
Lu Y, et al. Yin Yang 1 promotes hepatic steatosis through repression of farnesoid X receptor in obese mice. Gut. 2014;63(1):170-178.
-
(2014)
Gut.
, vol.63
, Issue.1
, pp. 170-178
-
-
Lu, Y.1
-
14
-
-
33846892749
-
The genetic landscape of type 2 diabetes in mice
-
Clee SM, Attie AD. The genetic landscape of type 2 diabetes in mice. Endocr Rev. 2007;28(1):48-83.
-
(2007)
Endocr Rev.
, vol.28
, Issue.1
, pp. 48-83
-
-
Clee, S.M.1
Attie, A.D.2
-
15
-
-
84882890178
-
Irisin is inversely associated with intrahepatic triglyceride contents in obese adults
-
Zhang HJ, et al. Irisin is inversely associated with intrahepatic triglyceride contents in obese adults. J Hepatol. 2013;59(3):557-562.
-
(2013)
J Hepatol.
, vol.59
, Issue.3
, pp. 557-562
-
-
Zhang, H.J.1
-
16
-
-
84862908953
-
Glucose-mediated repression of menin promotes pancreatic β-cell proliferation
-
Zhang H, et al. Glucose-mediated repression of menin promotes pancreatic β-cell proliferation. Endocrinology. 2012;153(2):602-611.
-
(2012)
Endocrinology
, vol.153
, Issue.2
, pp. 602-611
-
-
Zhang, H.1
-
17
-
-
33746536677
-
Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis
-
Uyeda K, Repa JJ. Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis. Cell Metab. 2006;4(2):107-110.
-
(2006)
Cell Metab.
, vol.4
, Issue.2
, pp. 107-110
-
-
Uyeda, K.1
Repa, J.J.2
-
18
-
-
84861809881
-
The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans
-
Benhamed F, et al. The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans. J Clin Invest. 2012;122(6):2176-2194.
-
(2012)
J Clin Invest.
, vol.122
, Issue.6
, pp. 2176-2194
-
-
Benhamed, F.1
-
19
-
-
40549135297
-
Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: Lessons from genetically engineered mice
-
Postic C, Girard J. Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice. J Clin Invest. 2008;118(3):829-838.
-
(2008)
J Clin Invest.
, vol.118
, Issue.3
, pp. 829-838
-
-
Postic, C.1
Girard, J.2
-
20
-
-
33645828659
-
Lipid metabolism and liver inflammation. II. Fatty liver disease and fatty acid oxidation
-
Reddy JK, Rao MS. Lipid metabolism and liver inflammation. II. Fatty liver disease and fatty acid oxidation. Am J Physiol Gastrointest Liver Physiol. 2006;290(5):852-858.
-
(2006)
Am J Physiol Gastrointest Liver Physiol.
, vol.290
, Issue.5
, pp. 852-858
-
-
Reddy, J.K.1
Rao, M.S.2
-
21
-
-
77955057772
-
PPARalpha: An emerging therapeutic target in diabetic microvascular damage
-
Hiukka A, Maranghi M, Matikainen N, Taskinen MR. PPARalpha: an emerging therapeutic target in diabetic microvascular damage. Nat Rev Endocrinol. 2010;6(8):454-463.
-
(2010)
Nat Rev Endocrinol.
, vol.6
, Issue.8
, pp. 454-463
-
-
Hiukka, A.1
Maranghi, M.2
Matikainen, N.3
Taskinen, M.R.4
-
22
-
-
0035923665
-
SP600125, an anthrapyrazolone inhibitor of Jun. N-terminal kinase
-
Bennett BL, et al. SP600125, an anthrapyrazolone inhibitor of Jun. N-terminal kinase. Proc Natl Acad Sci U S A. 2001;98(24):13681-13686.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, Issue.24
, pp. 13681-13686
-
-
Bennett, B.L.1
-
23
-
-
0037113091
-
The integrin beta tail is required and sufficient to regulate adhesion signaling to Rac1
-
Berrier AL, Martinez R, Bokoch GM, LaFlamme SE. The integrin beta tail is required and sufficient to regulate adhesion signaling to Rac1. J Cell Sci. 2002;115(pt 22):4285-4291.
-
(2002)
J Cell Sci.
, vol.115
, Issue.PART 22
, pp. 4285-4291
-
-
Berrier, A.L.1
Martinez, R.2
Bokoch, G.M.3
LaFlamme, S.E.4
-
24
-
-
34250740938
-
β1 Integrin activates Rac1 in Schwann cells to generate radial lamellae during axonal sorting and myelination
-
Nodari A, et al. β1 Integrin activates Rac1 in Schwann cells to generate radial lamellae during axonal sorting and myelination. J Cell Biol. 2007;177(6):1063-1075.
-
(2007)
J Cell Biol.
, vol.177
, Issue.6
, pp. 1063-1075
-
-
Nodari, A.1
-
25
-
-
0038344831
-
Upregulation of the Rac1/JNK signaling pathway in primary human schwannoma cells
-
Kaempchen K, Mielke K, Utermark T, Langmesser S, Hanemann CO. Upregulation of the Rac1/JNK signaling pathway in primary human schwannoma cells. Hum Mol Genet. 2003;12(11):1211-1221.
-
(2003)
Hum Mol Genet.
, vol.12
, Issue.11
, pp. 1211-1221
-
-
Kaempchen, K.1
Mielke, K.2
Utermark, T.3
Langmesser, S.4
Hanemann, C.O.5
-
26
-
-
83555162619
-
Cdc42 and Rac1 are major contributors to the saturated fatty acidstimulated JNK pathway in hepatocytes
-
Sharma M, Urano F, Jaeschke A. Cdc42 and Rac1 are major contributors to the saturated fatty acidstimulated JNK pathway in hepatocytes. J Hepatol. 2012;56(1):192-198.
-
(2012)
J Hepatol.
, vol.56
, Issue.1
, pp. 192-198
-
-
Sharma, M.1
Urano, F.2
Jaeschke, A.3
-
27
-
-
2442664118
-
Rational design and characterization of a Rac GTPase-specific small molecule inhibitor
-
Gao Y, Dickerson JB, Guo F, Zheng J, Zheng Y. Rational design and characterization of a Rac GTPase-specific small molecule inhibitor. Proc Natl Acad Sci USA. 2004;101(20):7618-7623.
-
(2004)
Proc Natl Acad Sci USA.
, vol.101
, Issue.20
, pp. 7618-7623
-
-
Gao, Y.1
Dickerson, J.B.2
Guo, F.3
Zheng, J.4
Zheng, Y.5
-
28
-
-
0036013438
-
Characterization of the human PPARalpha promoter: Identification of a functional nuclear receptor response element
-
Pineda Torra I, Jamshidi Y, Flavell DM, Fruchart JC, Staels B. Characterization of the human PPARalpha promoter: identification of a functional nuclear receptor response element. Mol Endocrinol. 2002;16(5):1013-1028.
-
(2002)
Mol Endocrinol.
, vol.16
, Issue.5
, pp. 1013-1028
-
-
Torra, I.P.1
Jamshidi, Y.2
Flavell, D.M.3
Fruchart, J.C.4
Staels, B.5
-
29
-
-
79960472726
-
Deletion of steroid receptor coactivator-3 gene ameliorates hepatic steatosis
-
Ma X, et al. Deletion of steroid receptor coactivator-3 gene ameliorates hepatic steatosis. J Hepatol. 2011;55(2):445-452.
-
(2011)
J Hepatol.
, vol.55
, Issue.2
, pp. 445-452
-
-
Ma, X.1
-
30
-
-
64249083389
-
The nuclear receptor CAR (NR1I3) regulates serum triglyceride levels under conditions of metabolic stress
-
Maglich JM, Lobe DC, Moore JT. The nuclear receptor CAR (NR1I3) regulates serum triglyceride levels under conditions of metabolic stress. J Lipid Res. 2009;50(3):439-445.
-
(2009)
J Lipid Res.
, vol.50
, Issue.3
, pp. 439-445
-
-
Maglich, J.M.1
Lobe, D.C.2
Moore, J.T.3
-
31
-
-
84859974016
-
Retinoic acid receptor-related orphan receptor α-induced activation of adenosine monophosphate-activated protein kinase results in attenuation of hepatic steatosis
-
Kim EJ, et al. Retinoic acid receptor-related orphan receptor α-induced activation of adenosine monophosphate-activated protein kinase results in attenuation of hepatic steatosis. Hepatology. 2012;55(5):1379-1388.
-
(2012)
Hepatology
, vol.55
, Issue.5
, pp. 1379-1388
-
-
Kim, E.J.1
-
32
-
-
33646142778
-
Glucose-induced repression of PPARa gene expression in pancreatic beta-cells involves PP2A activation and AMPK inactivation
-
Ravnskjaer K, Boergesen M, Dalgaard LT, Mandrup S. Glucose-induced repression of PPARa gene expression in pancreatic beta-cells involves PP2A activation and AMPK inactivation. J Mol Endocrinol. 2006;36(2):289-299.
-
(2006)
J Mol Endocrinol.
, vol.36
, Issue.2
, pp. 289-299
-
-
Ravnskjaer, K.1
Boergesen, M.2
Dalgaard, L.T.3
Mandrup, S.4
-
33
-
-
79953886811
-
ChREBP mediates glucose repression of peroxisome proliferator-activated receptor a expression in pancreatic β-cells
-
Boergesen M, Poulsen Ll, Schmidt SF, Frigerio F, Maechler P, Mandrup S. ChREBP mediates glucose repression of peroxisome proliferator-activated receptor a expression in pancreatic β-cells. J Biol Chem. 2011;286(15):13214-13225.
-
(2011)
J Biol Chem.
, vol.286
, Issue.15
, pp. 13214-13225
-
-
Boergesen, M.1
Poulsen, Ll.2
Schmidt, S.F.3
Frigerio, F.4
Maechler, P.5
Mandrup, S.6
-
34
-
-
84864981474
-
Periostin activates integrin a5β1 through a PI3K/AKT-dependent pathway in invasion of cholangiocarcinoma
-
Utispan K. Periostin activates integrin a5β1 through a PI3K/AKT-dependent pathway in invasion of cholangiocarcinoma. Int J Oncol. 2012;41(3):1110-1118.
-
(2012)
Int J Oncol.
, vol.41
, Issue.3
, pp. 1110-1118
-
-
Utispan, K.1
-
35
-
-
67349256386
-
Upregulated expression of periostin by hypoxia in non-small-cell lung cancer cells promotes cell survival via the Akt/PKB pathway
-
Ouyang G, Liu M, Ruan K, Song G, Mao Y, Bao S. Upregulated expression of periostin by hypoxia in non-small-cell lung cancer cells promotes cell survival via the Akt/PKB pathway. Cancer Lett. 2009;281(2):213-219.
-
(2009)
Cancer Lett.
, vol.281
, Issue.2
, pp. 213-219
-
-
Ouyang, G.1
Liu, M.2
Ruan, K.3
Song, G.4
Mao, Y.5
Bao, S.6
-
36
-
-
0037153158
-
A central role for JNK in obesity and insulin resistance
-
Hirosumi J, et al. A central role for JNK in obesity and insulin resistance. Nature. 2002;420(6913):333-336.
-
(2002)
Nature
, vol.420
, Issue.6913
, pp. 333-336
-
-
Hirosumi, J.1
-
37
-
-
78650280416
-
JNK regulation of hepatic manifestations of the metabolic syndrome
-
Czaja MJ. JNK regulation of hepatic manifestations of the metabolic syndrome. Trends Endocrinol Metab. 2010;21(12):707-713.
-
(2010)
Trends Endocrinol Metab.
, vol.21
, Issue.12
, pp. 707-713
-
-
Czaja, M.J.1
-
38
-
-
84864198388
-
A liver full of JNK: Signaling in regulation of cell function and disease pathogenesis, and clinical approaches
-
Seki E, Brenner DA, Karin M. A liver full of JNK: signaling in regulation of cell function and disease pathogenesis, and clinical approaches. Gastroenterology. 2012;143(2):307-320.
-
(2012)
Gastroenterology
, vol.143
, Issue.2
, pp. 307-320
-
-
Seki, E.1
Brenner, D.A.2
Karin, M.3
-
39
-
-
33750823407
-
Saturated fatty acids inhibit induction of insulin gene transcription by JNK-mediated phosphorylation of insulin-receptor substrates
-
Solinas G, Naugler W, Galimi F, Lee MS, Karin M. Saturated fatty acids inhibit induction of insulin gene transcription by JNK-mediated phosphorylation of insulin-receptor substrates. Proc Natl Acad Sci U S A. 2006;103(44):16454- 16459.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.44
, pp. 16454-16459
-
-
Solinas, G.1
Naugler, W.2
Galimi, F.3
Lee, M.S.4
Karin, M.5
-
40
-
-
33746101818
-
Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance
-
Tuncman G, Hirosumi J, Solinas G, Chang L, Karin M, Hotamisligil GS. Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance. Proc Natl Acad Sci U S A. 2006;103(28):10741-10746.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.28
, pp. 10741-10746
-
-
Tuncman, G.1
Hirosumi, J.2
Solinas, G.3
Chang, L.4
Karin, M.5
Hotamisligil, G.S.6
-
41
-
-
33644813043
-
JNK1 but not JNK2 promotes the development of steatohepatitis in mice
-
Schattenberg JM, et al. JNK1 but not JNK2 promotes the development of steatohepatitis in mice. Hepatology. 2006;43(1):163-172.
-
(2006)
Hepatology
, vol.43
, Issue.1
, pp. 163-172
-
-
Schattenberg, J.M.1
-
42
-
-
58949093454
-
Differential effects of JNK1 and JNK2 inhibition on murine steatohepatitis and insulin resistance
-
Singh R, Wang Y, Xiang Y, Tanaka KE, Gaarde WA, Czaja MJ. Differential effects of JNK1 and JNK2 inhibition on murine steatohepatitis and insulin resistance. Hepatology. 2009;49(1):87-96.
-
(2009)
Hepatology
, vol.49
, Issue.1
, pp. 87-96
-
-
Singh, R.1
Wang, Y.2
Xiang, Y.3
Tanaka, K.E.4
Gaarde, W.A.5
Czaja, M.J.6
-
43
-
-
33644652183
-
Sorting out the roles of PPARa in energy metabolism and vascular homeostasis
-
Lefebvre P, Chinetti G, Fruchart JC, Staels B. Sorting out the roles of PPARa in energy metabolism and vascular homeostasis. J Clin Invest. 2006;116(3):571-580.
-
(2006)
J Clin Invest.
, vol.116
, Issue.3
, pp. 571-580
-
-
Lefebvre, P.1
Chinetti, G.2
Fruchart, J.C.3
Staels, B.4
-
44
-
-
0032699670
-
Peroxisome proliferatoractivated receptor a mediates the adaptive response to fasting
-
Kersten S, Seydoux J, Peters JM, Gonzalez FJ, Desvergne B, Wahli W. Peroxisome proliferatoractivated receptor a mediates the adaptive response to fasting. J Clin Invest. 1999;103(11):1489-1498.
-
(1999)
J Clin Invest.
, vol.103
, Issue.11
, pp. 1489-1498
-
-
Kersten, S.1
Seydoux, J.2
Peters, J.M.3
Gonzalez, F.J.4
Desvergne, B.5
Wahli, W.6
-
45
-
-
48349108293
-
Genome-wide coactivation analysis of PGC-1a identifies BAF60a as a regulator of hepatic lipid metabolism
-
Li S, et al. Genome-wide coactivation analysis of PGC-1a identifies BAF60a as a regulator of hepatic lipid metabolism. Cell Metab. 2008;8(2):105-117.
-
(2008)
Cell Metab.
, vol.8
, Issue.2
, pp. 105-117
-
-
Li, S.1
-
46
-
-
63449112017
-
Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation
-
Purushotham A, Schug TT, Xu Q, Surapureddi S, Guo X, Li X. Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation. Cell Metab. 2009;9(4):327-338.
-
(2009)
Cell Metab.
, vol.9
, Issue.4
, pp. 327-338
-
-
Purushotham, A.1
Schug, T.T.2
Xu, Q.3
Surapureddi, S.4
Guo, X.5
Li, X.6
-
47
-
-
79953765467
-
Hepatic deficiency in transcriptional cofactor TBL1 promotes liver steatosis and hypertriglyceridemia
-
Kulozik P, et al. Hepatic deficiency in transcriptional cofactor TBL1 promotes liver steatosis and hypertriglyceridemia. Cell Metab. 2011;13(4):389-400.
-
(2011)
Cell Metab.
, vol.13
, Issue.4
, pp. 389-400
-
-
Kulozik, P.1
-
48
-
-
49849093922
-
A Val227Ala substitution in the peroxisome proliferator activated receptor a (PPARa) gene associated with non-alcoholic fatty liver disease and decreased waist circumference and waist-to-hip ratio
-
Chen S, Li Y, Li S, Yu C. A Val227Ala substitution in the peroxisome proliferator activated receptor a (PPARa) gene associated with non-alcoholic fatty liver disease and decreased waist circumference and waist-to-hip ratio. J Gastroenterol Hepatol. 2008;23(9):1415-1418.
-
(2008)
J Gastroenterol Hepatol.
, vol.23
, Issue.9
, pp. 1415-1418
-
-
Chen, S.1
Li, Y.2
Li, S.3
Yu, C.4
-
49
-
-
47749134925
-
Association between PPARGC1A polymorphisms and the occurrence of nonalcoholic fatty liver disease (NAFLD)
-
Yoneda M, et al. Association between PPARGC1A polymorphisms and the occurrence of nonalcoholic fatty liver disease (NAFLD). BMC Gastroenterol. 2008;8:27.
-
(2008)
BMC Gastroenterol.
, vol.8
, pp. 27
-
-
Yoneda, M.1
-
50
-
-
0033004986
-
Recognition and management of fatty acid oxidation defects: A series of 107 patients
-
Saudubray JM, et al. Recognition and management of fatty acid oxidation defects: a series of 107 patients. J Inherit Metab Dis. 1999;22(4):488-502.
-
(1999)
J Inherit Metab Dis.
, vol.22
, Issue.4
, pp. 488-502
-
-
Saudubray, J.M.1
-
51
-
-
79953321200
-
Genetic determinants of hepatic steatosis in man
-
Hooper AJ, Adams LA, Burnett JR. Genetic determinants of hepatic steatosis in man. J Lipid Res. 2011;52(4):593-617.
-
(2011)
J Lipid Res.
, vol.52
, Issue.4
, pp. 593-617
-
-
Hooper, A.J.1
Adams, L.A.2
Burnett, J.R.3
-
52
-
-
35148881190
-
Re-evaluation of fatty acid metabolism-related gene expression in nonalcoholic fatty liver disease
-
Kohjima M, et al. Re-evaluation of fatty acid metabolism-related gene expression in nonalcoholic fatty liver disease. Int J Mol Med. 2007;20(3):351-358.
-
(2007)
Int J Mol Med.
, vol.20
, Issue.3
, pp. 351-358
-
-
Kohjima, M.1
-
53
-
-
84872151568
-
Misregulation of PPAR functioning and its pathogenic consequences associated with nonalcoholic fatty liver disease in human obesity
-
Videla LA, Pettinelli P. Misregulation of PPAR functioning and its pathogenic consequences associated with nonalcoholic fatty liver disease in human obesity. PPAR Res. 2012;2012:107434.
-
(2012)
PPAR Res.
, vol.2012
, pp. 107434
-
-
Videla, L.A.1
Pettinelli, P.2
-
54
-
-
4744359039
-
Association between the PPARa-L162V polymorphism and components of the metabolic syndrome
-
Robitaille J, et al. Association between the PPARa-L162V polymorphism and components of the metabolic syndrome. J Hum Genet. 2004;49(9):482-489.
-
(2004)
J Hum Genet.
, vol.49
, Issue.9
, pp. 482-489
-
-
Robitaille, J.1
-
55
-
-
12744280698
-
Peroxisome proliferator-activated receptor alpha gene variation influences age of onset and progression of type 2 diabetes
-
Flavell DM, et al. Peroxisome proliferator-activated receptor alpha gene variation influences age of onset and progression of type 2 diabetes. Diabetes. 2005;54(2):582-586.
-
(2005)
Diabetes
, vol.54
, Issue.2
, pp. 582-586
-
-
Flavell, D.M.1
-
56
-
-
33846382723
-
Relationships between the functional PPARalpha Leu162Val polymorphism and obesity, type 2 diabetes, dyslipidaemia, and related quantitative traits in studies of 5799 middleaged white people
-
Sparsø T, et al. Relationships between the functional PPARalpha Leu162Val polymorphism and obesity, type 2 diabetes, dyslipidaemia, and related quantitative traits in studies of 5799 middleaged white people. Mol Genet Metab. 2007;90(2):205-209.
-
(2007)
Mol Genet Metab.
, vol.90
, Issue.2
, pp. 205-209
-
-
Sparsø, T.1
-
57
-
-
77955483485
-
*3-Leiden. CETP mice
-
*3-Leiden. CETP mice. J Biol Chem. 2010;285(33):25168-25175.
-
(2010)
J Biol Chem.
, vol.285
, Issue.33
, pp. 25168-25175
-
-
Bijland, S.1
-
58
-
-
84878218164
-
Activation of PPARa ameliorates hepatic insulin resistance and steatosis in high fructose-fed mice despite increased endoplasmic reticulum stress
-
Chan SM, et al. Activation of PPARa ameliorates hepatic insulin resistance and steatosis in high fructose-fed mice despite increased endoplasmic reticulum stress. Diabetes. 2013;62(6):2095-2105.
-
(2013)
Diabetes
, vol.62
, Issue.6
, pp. 2095-2105
-
-
Chan, S.M.1
-
59
-
-
84885769159
-
Current role of fenofibrate in the prevention and management of non-alcoholic fatty liver disease
-
Kostapanos MS, Kei A, Elisaf MS. Current role of fenofibrate in the prevention and management of non-alcoholic fatty liver disease. World J Hepatol. 2013;5(9):470-478.
-
(2013)
World J Hepatol.
, vol.5
, Issue.9
, pp. 470-478
-
-
Kostapanos, M.S.1
Kei, A.2
Elisaf, M.S.3
-
60
-
-
0033594768
-
Bezafibrate for tamoxifen-induced non-alcoholic steatohepatitis
-
Saibara T, Onishi S, Ogawa Y, Yoshida S, Enzan H. Bezafibrate for tamoxifen-induced non-alcoholic steatohepatitis. Lancet. 1999;353(9166):1802.
-
(1999)
Lancet
, vol.353
, Issue.9166
, pp. 1802
-
-
Saibara, T.1
Onishi, S.2
Ogawa, Y.3
Yoshida, S.4
Enzan, H.5
-
61
-
-
33745046866
-
Effect of multifactorial treatment on non-alcoholic fatty liver disease in metabolic syndrome: A randomised study
-
Athyros VG, et al. Effect of multifactorial treatment on non-alcoholic fatty liver disease in metabolic syndrome: a randomised study. Curr Med Res Opin. 2006;22(5):873-883.
-
(2006)
Curr Med Res Opin.
, vol.22
, Issue.5
, pp. 873-883
-
-
Athyros, V.G.1
-
62
-
-
80054694121
-
Inhibition of c-Jun-N-terminal kinase increases cardiac peroxisome proliferatoractivated receptor a expression and fatty acid oxidation and prevents lipopolysaccharideinduced heart dysfunction
-
Drosatos K, et al. Inhibition of c-Jun-N-terminal kinase increases cardiac peroxisome proliferatoractivated receptor a expression and fatty acid oxidation and prevents lipopolysaccharideinduced heart dysfunction. J Biol Chem. 2011;286(42):36331-36339.
-
(2011)
J Biol Chem.
, vol.286
, Issue.42
, pp. 36331-36339
-
-
Drosatos, K.1
-
63
-
-
4344668155
-
RORalpha regulates the expression of genes involved in lipid homeostasis in skeletal muscle cells: Caveolin-3 and CPT-1 are direct targets of ROR
-
Lau P, Nixon SJ, Parton RG, Muscat GE. RORalpha regulates the expression of genes involved in lipid homeostasis in skeletal muscle cells: caveolin-3 and CPT-1 are direct targets of ROR. J Biol Chem. 2004;279(35):36828-36840.
-
(2004)
J Biol Chem.
, vol.279
, Issue.35
, pp. 36828-36840
-
-
Lau, P.1
Nixon, S.J.2
Parton, R.G.3
Muscat, G.E.4
-
64
-
-
0026513957
-
Functional antagonism between c-Jun. and MyoD proteins: A direct physical association
-
Bengal E, et al. Functional antagonism between c-Jun. and MyoD proteins: a direct physical association. Cell. 1992;68(3):507-519.
-
(1992)
Cell
, vol.68
, Issue.3
, pp. 507-519
-
-
Bengal, E.1
-
65
-
-
0032572723
-
Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription
-
Zhang Y, Feng XH, Derynck R. Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription. Nature. 1998;394(6696):909-913.
-
(1998)
Nature
, vol.394
, Issue.6696
, pp. 909-913
-
-
Zhang, Y.1
Feng, X.H.2
Derynck, R.3
-
66
-
-
84896388318
-
Hepatic steatosis exacerbated by endoplasmic reticulum stress-mediated downregulation of FXR in aging mice
-
Xiong X, et al. Hepatic steatosis exacerbated by endoplasmic reticulum stress-mediated downregulation of FXR in aging mice. J Hepatol. 2014;60(4):847-854.
-
(2014)
J Hepatol.
, vol.60
, Issue.4
, pp. 847-854
-
-
Xiong, X.1
-
67
-
-
34249711964
-
Hepatic fibroblast growth factor 21 is regulated by PPARa and is a key mediator of hepatic lipid metabolism in ketotic states
-
Badman MK, Pissios P, Kennedy AR, Koukos G, Flier JS, Maratos-Flier E. Hepatic fibroblast growth factor 21 is regulated by PPARa and is a key mediator of hepatic lipid metabolism in ketotic states. Cell Metab. 2007;5(6):426-437.
-
(2007)
Cell Metab.
, vol.5
, Issue.6
, pp. 426-437
-
-
Badman, M.K.1
Pissios, P.2
Kennedy, A.R.3
Koukos, G.4
Flier, J.S.5
Maratos-Flier, E.6
-
68
-
-
57349109502
-
Fetuin-A and its relation to metabolic syndrome and fatty liver disease in obese children before and after weight loss
-
Reinehr T, Roth CL. Fetuin-A and its relation to metabolic syndrome and fatty liver disease in obese children before and after weight loss. J Clin Endocrinol Metab. 2008;93(11):4479-4485.
-
(2008)
J Clin Endocrinol Metab.
, vol.93
, Issue.11
, pp. 4479-4485
-
-
Reinehr, T.1
Roth, C.L.2
-
69
-
-
79957521884
-
Pancreatic-derived factor promotes lipogenesis in the mouse liver: Role of the Forkhead box 1 signaling pathway
-
Li J, et al. Pancreatic-derived factor promotes lipogenesis in the mouse liver: role of the Forkhead box 1 signaling pathway. Hepatology. 2011;53(6):1906-1916.
-
(2011)
Hepatology
, vol.53
, Issue.6
, pp. 1906-1916
-
-
Li, J.1
-
70
-
-
77955474305
-
Increased fibroblast growth factor 21 in obesity and nonalcoholic fatty liver disease
-
Dushay J, et al. Increased fibroblast growth factor 21 in obesity and nonalcoholic fatty liver disease. Gastroenterology. 2010;139(2):456-463.
-
(2010)
Gastroenterology
, vol.139
, Issue.2
, pp. 456-463
-
-
Dushay, J.1
-
71
-
-
84875549943
-
The role of hepatokines in metabolism
-
Stefan N, Häring HU. The role of hepatokines in metabolism. Nat Rev Endocrinol. 2013;9(3):144-152.
-
(2013)
Nat Rev Endocrinol.
, vol.9
, Issue.3
, pp. 144-152
-
-
Stefan, N.1
Häring, H.U.2
-
72
-
-
84896139052
-
Production of monoclonal antibodies
-
Unit 2.5
-
Yokoyama WM, et al. Production of monoclonal antibodies. Curr Protoc Immunol. 2013;102:Unit 2.5.
-
(2013)
Curr Protoc Immunol.
, vol.102
-
-
Yokoyama, W.M.1
|