Pre-administration of G9a/GLP inhibitor during synaptogenesis prevents postnatal ethanol-induced LTP deficits and neurobehavioral abnormalities in adult mice

Experimental Neurology

Volumn 261, Issue , 2014, Pages 34-43

  Subbanna, Shivakumar ^a   Basavarajappa, Balapal S ^a,b,c  

^a NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

^b NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

^c Department of Psychiatry College of Physicians and Surgeons Columbia University ^*  (United States)

Author keywords

Bix; Epigenetics; Ethanol; FASD; H3K9; Histones; Memory loss; Methyltransferase; Postnatal development; Synaptic plasticity

Indexed keywords

ALCOHOL; HISTONE H3; N (1 BENZYL 4 PIPERIDINYL) 2 (HEXAHYDRO 4 METHYL 1H 1,4 DIAZEPIN 1 YL) 6,7 DIMETHOXY 4 QUINAZOLINAMINE; AZEPINE DERIVATIVE; CENTRAL DEPRESSANT AGENT; ENZYME INHIBITOR; HISTONE LYSINE METHYLTRANSFERASE; QUINAZOLINE DERIVATIVE;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; EXCITATORY POSTSYNAPTIC POTENTIAL; EXPLORATORY BEHAVIOR; HIPPOCAMPUS; HISTONE METHYLATION; LONG TERM POTENTIATION; MALE; MEMORY; MOUSE; NERVE DEGENERATION; NEUROPROTECTION; NEWBORN; NONHUMAN; NOVEL OBJECT RECOGNITION TEST; PERINATAL DRUG EXPOSURE; PRIORITY JOURNAL; RETROSPLENIAL CORTEX; SOCIAL COGNITION; SPATIAL MEMORY; SYNAPTOGENESIS; Y-MAZE TEST; AMNESIA; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL MODEL; EXPERIMENTAL BEHAVIORAL TEST; MENTAL PERFORMANCE; OBJECT RECOGNITION MEMORY; SPATIAL RECOGNITION MEMORY; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CHEMICALLY INDUCED; DRUG ADMINISTRATION; DRUG EFFECTS; ELECTROSTIMULATION; GENE EXPRESSION REGULATION; IN VITRO STUDY; MAZE TEST; MEMORY DISORDERS; NERVOUS SYSTEM DEVELOPMENT; RECOGNITION; SOCIAL BEHAVIOR;

ANIMALS; ANIMALS, NEWBORN; AZEPINES; CENTRAL NERVOUS SYSTEM DEPRESSANTS; DRUG ADMINISTRATION SCHEDULE; ELECTRIC STIMULATION; ENZYME INHIBITORS; ETHANOL; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HISTONE-LYSINE N-METHYLTRANSFERASE; IN VITRO TECHNIQUES; LONG-TERM POTENTIATION; MALE; MAZE LEARNING; MEMORY DISORDERS; MICE; MICE, INBRED C57BL; NEUROGENESIS; QUINAZOLINES; RECOGNITION (PSYCHOLOGY); SOCIAL BEHAVIOR;

EID: 84905235036     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2014.07.003     Document Type: Article

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