Voluntary exercise rescues deficits in spatial memory and long-term potentiation in prenatal ethanol-exposed male rats

European Journal of Neuroscience

Volumn 21, Issue 6, 2005, Pages 1719-1726

  Christie, Brian R ^a   Swann, Sarah E ^a   Fox, Christopher J ^a   Froc, David ^a   Lieblich, Stephanie E ^a   Redila, Van ^a   Webber, Alina ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Dentate gyrus; FAS; Hippocampus; LTP; Watermaze

Indexed keywords

ALCOHOL; DEXTRIN; MALTOSE;

ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CAGE; CONDITIONING; CONTROLLED STUDY; DENTATE GYRUS; EXERCISE; FEMALE; HIPPOCAMPUS; LONG TERM POTENTIATION; MALE; MAZE TEST; MEMORY DISORDER; NONHUMAN; PERINATAL PERIOD; PREGNANCY; PRENATAL EXPOSURE; PRIORITY JOURNAL; RAT; RUNNING; SPATIAL MEMORY; WEANING;

ANIMALS; ETHANOL; FEMALE; LONG-TERM POTENTIATION; MALE; MEMORY; PHYSICAL CONDITIONING, ANIMAL; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, SPRAGUE-DAWLEY; SPATIAL BEHAVIOR;

EID: 18444400234     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2005.04004.x     Document Type: Article

References (42)

1. Adlard, P.A., Perreau, V.M., Engesser-Cesar, C. & Cotman, C.W. (2004) The timecourse of induction of brain-derived neurotrophic factor mRNA and protein in the rat hippocampus following voluntary exercise. Neurosci. Lett., 363, 43-48.
2. Akaneya, Y., Tsumoto, T., Kinoshita, S. & Hatanaka, H. (1997) Brain-derived neurotrophic factor enhances long-term potentiation in rat visual cortex. J. Neurosci., 17, 6707-6716.
3. Anderson, B.J., Rapp, D.N., Baek, D.H., McCloskey, D.P., Coburn-Litvak, P.S. & Robinson, J.K. (2000) Exercise influences spatial learning in the radial arm maze. Physiol. Behav., 70, 425-429.
4. Berchtold, N.C., Kesslak, J.P., Pike, C.J., Adlard, P.A. & Cotman, C.W. (2001) Estrogen and exercise interact to regulate brain-derived neurotrophic factor mRNA and protein expression in the hippocampus. Eur. J. Neurosci., 14, 1992-2002.
5. Berman, R.F. & Hannigan, J.H. (2000) Effects of prenatal alcohol exposure on the hippocampus: spatial behavior, electrophysiology, and neuroanatomy. Hippocampus, 10, 94-110.
6. Blanchard, B.A., Riley, E.P. & Hannigan, J.H. (1987) Deficits on a spatial navigation task following prenatal exposure to ethanol. Neurotoxicol. Teratol., 9, 253-258.
7. Christie, B.R. & Abraham, W.C. (1992a) Priming of associative long-term depression in the dentate gyrus by theta frequency synaptic activity. Neuron, 9, 79-84.
8. Christie, B.R. & Abraham, W.C. (1992b) NMDA-dependent heterosynaptic long-term depression in the dentate gyrus of anaesthetized rats. Synapse, 10, 1-6.
9. Cotman, C.W. & Berchtold, N.C. (2002) Exercise: a behavioral intervention to enhance brain health and plasticity. TINS, 25, 295-301.
10. Droste, S.K., Gesing, A., Ulbricht, S., Muller, M.B., Linthorst, A.C. & Reul, J.M. (2003) Effects of long-term voluntary exercise on the mouse hypothalamic-pituitary-adrenocortical axis. Endocrinology, 144, 3012-3023.
11. Farmer, J., Zhao, X., van Praag, H., Wodtke, K., Gage, F.H. & Christie, B.R. (2004) Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male Sprague-Dawley rats in vivo. Neuroscience, 124, 71-79.
12. Fordyce, D.E. & Farrar, R.P. (1991) Physical activity effects on hippocampal and parietal cortical cholinergic function and spatial learning in F344 rats. Behav. Brain Res., 43, 115-123.
13. Girard, T.A., Xing, H.C., Ward, G.R. & Wainwright, P.E. (2000) Early postnatal ethanol exposure has long-term effects on the performance of male rats in a delayed matching-to-place task in the Morris water maze. Alcohol Clin. Exp. Res., 24, 300-306.
14. Griesbach, G.S., Hovda, D.A., Molteni, R., Wu, A. & Gomez-Pinilla, F. (2004) Voluntary exercise following traumatic brain injury: brain-derived neurotrophic factor upregulation and recovery of function. Neuroscience, 125, 129-139.
15. Hamilton, D.A., Kodituwakku, P., Sutherland, R.J. & Savage, D.D. (2003) Children with Fetal Alcohol Syndrome are impaired at place learning but not cued-navigation in a virtual Morris water task. Behav. Brain Res., 143, 85-94.
16. Heaton, M.B., Mitchell, J.J., Paiva, M. & Walker, D.W. (2000) Ethanol-induced alterations in the expression of neurotrophic factors in the developing rat central nervous system. Brain Res. Dev. Brain Res., 121, 97-107.
17. Huber, K.M., Sawtell, N.B. & Bear, M.F. (1998) Brain-derived neurotrophic factor alters the synaptic modification threshold in visual cortex. Neuropharmacology, 37, 571-579.
18. Iqbal, U., Dringenberg, H.C., Brien, J.F. & Reynolds, J.N. (2004) Chronic prenatal ethanol exposure alters hippocampal GABA(A) receptors and impairs spatial learning in the guinea pig. Behav. Brain Res., 150, 117-125.
19. Jones, K.L., Smith, D.W., Ulleland, C.N. & Streissguth, P. (1973) Pattern of malformation in offspring of chronic alcoholic mothers. Lancet, 1, 1267-1271.
20. Keiver, K. & Weinberg, J. (2003) Effect of duration of alcohol consumption on calcium and bone metabolism during pregnancy in the rat. Alcohol Clin. Exp. Res., 27, 1507-1519.
21. Keiver, K. & Weinberg, J. (2004) Effect of duration of maternal alcohol consumption on calcium metabolism and bone in the fetal rat. Alcohol Clin. Exp. Res., 28, 456-467.
22. Kerns, K.A., Don, A., Mateer, C.A. & Streissguth, A.P. (1997) Cognitive deficits in nonretarded adults with fetal alcohol syndrome. J. Learn Disabil., 30, 685-693.
23. Korte, M., Staiger, V., Griesbeck, O., Thoenen, H. & Bonhoeffer, T. (1996) The involvement of brain-derived neurotrophic factor in hippocampal long-term potentiation revealed by gene targeting experiments. J. Physiol. Paris, 90, 157-164.
24. Kovalchuk, Y., Hanse, E., Kafitz, K.W. & Konnerth, A. (2002) Postsynaptic Induction of BDNF-Mediated Long-Term Potentiation. Science, 295, 1729-1734.
25. Kramar, E.A., Lin, B., Lin, C.Y., Arai, A.C., Gall, C.M. & Lynch, G. (2004) A novel mechanism for the facilitation of theta-induced long-term potentiation by brain-derived neurotrophic factor. J. Neurosci., 24, 5151-5161.
26. Laurin, D., Verreault, R., Lindsay, J., MacPherson, K. & Rockwood, K. (2001) Physical activity and risk of cognitive impairment and dementia in elderly persons. Arch. Neurol., 58, 498-504.
27. Maier, S.E. & West, J.R. (2001) Regional differences in cell loss associated with binge-like alcohol exposure during the first two trimesters equivalent in the rat. Alcohol, 23, 49-57.
28. McNaughton, B.L. & Barnes, C.A. (1977) Physiological identification and analysis of dentate granule cell responses to stimulation of the medial and lateral perforant pathways in the rat. J. Comp. Neurol., 175, 439-454.
29. Molteni, R., Wu, A., Vaynman, S., Ying, Z., Barnard, R.J. & Gomez-Pinilla, F. (2004) Exercise reverses the harmful effects of consumption of a high-fat diet on synaptic and behavioral plasticity associated to the action of brain-derived neurotrophic factor. Neuroscience, 123, 429-440.
30. Morris, R.G., Garrud, P., Rawlins, J.N. & O'Keefe, J. (1982) Place navigation impaired in rats with hippocampal lesions. Nature, 297, 681-683.
31. Neeper, S.A., Gomez-Pinilla, F., Choi, J. & Cotman, C.W. (1996) Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain. Brain Res., 726, 49-56.
32. Patterson, S.L., Abel, T., Deuel, T.A., Martin, K.C., Rose, J.C. & Kandel, E.R. (1996) Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice. Neuron, 16, 1137-1145.
33. van Praag, H., Christie, B.R., Sejnowski, T.J. & Gage, F.H. (1999) Running enhances neurogenesis, learning, and long-term potentiation in mice. Proc. Natl Acad. Sci. USA, 96, 13427-13431.
34. Richardson, D.P., Byrnes, M.L., Brien, J.F., Reynolds, J.N. & Dringenberg, H.C. (2002) Impaired acquisition in the water maze and hippocampal long-term potentiation after chronic prenatal ethanol exposure in the guinea-pig. Eur. J. Neurosci., 16, 1593-1598.
35. Sampson, P.D., Streissguth, A.P., Bookstein, F.L., Little, R.E., Clarren, S.K., Dehaene, P., Hanson, J.W. & Graham, J.M. Jr (1997) Incidence of fetal alcohol syndrome and prevalence of alcohol-related neurodevelopmental disorder. Teratology, 56, 317-326.
36. Savage, D.D., Becher, M., de la Torre, A.J. & Sutherland, R.J. (2002) Dose-dependent effects of prenatal ethanol exposure on synaptic plasticity and learning in mature offspring. Alcohol Clin. Exp. Res., 26, 1752-1758.
37. Sokol, R.J., Delaney-Black, V. & Nordstrom, B. (2003) Fetal alcohol spectrum disorder. Jama, 290, 2996-2999.
38. Stratton, K.H.C. & Battaglia, F. (1996) Fetal Alcohol Syndrome: Diagnosis, Epidemiology, Prevention, and Treatment. National Academy Press, Washington, DC.
39. Streissguth, A.P., Sampson, P.D., Olson, H.C., Bookstein, F.L., Barr, H.M., Scott, M., Feldman, J. & Mirsky, A.F. (1994) Maternal drinking during pregnancy: attention and short-term memory in 14-year-old offspring - a longitudinal prospective study. Alcohol Clin. Exp. Res., 18, 202-218.
40. Sutherland, R.J., McDonald, R.J. & Savage, D.D. (1997) Prenatal exposure to moderate levels of ethanol can have long-lasting effects on hippocampal synaptic plasticity in adult offspring. Hippocampus, 7, 232-238.
41. Watanabe, T., Morimoto, A., Sakata, Y., Wada, M. & Murakami, N. (1991) The effect of chronic exercise on the pituitary-adrenocortical response in conscious rats. J. Physiol., 439, 691-699.
42. Weinberg, J. (1992) Prenatal ethanol effects: sex differences in offspring stress responsiveness. Alcohol, 9, 219-223.