Gestational choline supplementation normalized fetal alcohol-induced alterations in histone modifications, DNA methylation, and proopiomelanocortin (POMC) gene expression in β-endorphin-producing POMC neurons of the hypothalamus

Alcoholism: Clinical and Experimental Research

Volumn 37, Issue 7, 2013, Pages 1133-1142

  Bekdash, Rola A ^a   Zhang, Changqing ^a   Sarkar, Dipak K ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

Choline; DNA Methylation; Fetal Alcohol; Histone Modification; Proopiomelanocortin; Stress Axis

Indexed keywords

BETA ENDORPHIN; CHOLINE; CORTICOSTERONE; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; MESSENGER RNA; METHYL CPG BINDING PROTEIN 2; PROOPIOMELANOCORTIN;

ALCOHOL CONSUMPTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD SAMPLING; BRAIN NERVE CELL; CELL FUNCTION; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; DIET SUPPLEMENTATION; DNA METHYLATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION; GESTATIONAL AGE; HISTONE MODIFICATION; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROGENY; PROMOTER REGION; PROTEIN PHOSPHORYLATION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

CHOLINE; DNA METHYLATION; FETAL ALCOHOL; HISTONE MODIFICATION; PROOPIOMELANOCORTIN; STRESS AXIS;

ANIMALS; BETA-ENDORPHIN; CHOLINE; DIETARY SUPPLEMENTS; DNA METHYLATION; FEMALE; HISTONES; HYPOTHALAMUS; MALE; NEURONS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PRO-OPIOMELANOCORTIN; RATS;

RATTUS;

EID: 84879884147     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/acer.12082     Document Type: Article

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