Ethanol induced acetylation of histone at G9a exon1 and G9a-mediated histone H3 dimethylation leads to neurodegeneration in neonatal mice

Neuroscience

Volumn 258, Issue , 2014, Pages 422-432

  Subbanna, S ^a   Nagre, N N ^a   Shivakumar, M ^a   Umapathy, N S ^b   Psychoyos, D ^c   Basavarajappa, B S ^a,d,e  

^a NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

^c TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^d NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

^e NONE   (United States)

Author keywords

Apoptosis; Development; DNMT3A; Epigenetic; FASD; MeCP2

Indexed keywords

ALCOHOL; CASPASE 3; DNA METHYLTRANSFERASE 3A; HISTONE H3; METHYL CPG BINDING PROTEIN 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CONTROLLED STUDY; ENZYME DEGRADATION; EPIGENETICS; EXON; G9A GENE; HISTONE ACETYLATION; HISTONE METHYLATION; IMMUNOPRECIPITATION; MOUSE; NERVE DEGENERATION; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; THIRD TRIMESTER PREGNANCY;

ANALYSIS OF VARIANCE; ANOVA; APOPTOSIS; BELS; BLOOD ETHANOL LEVELS; CASPASE 3-CLEAVED-TAU; CC3; CDNA; CHIP; CHROMATIN IMMUNOPRECIPITATION; CLEAVED CASPASE-3 (ASP175); COMPLEMENTARY DNA; CTAU; DEVELOPMENT; DNA METHYLTRANSFERASE; DNMT3A; EPIGENETIC; FASD; G9A-RELATED PROTEIN; GLP; H3K27ME2; H3K9ME2; HISTONE H3 LYSINE 27; HISTONE H3 LYSINE 9; HPRT; HYPOXANTHINEPHOPHORIBOSYLTRANSFERASE; IMMUNOPRECIPITATES; IPS; MECP2; METHYL-CPG-BINDING PROTEIN 2; QPCR; QUANTITATIVE REAL-TIME POLYMERASE CHAIN REACTION;

ACETYLATION; ANIMALS; BRAIN; CENTRAL NERVOUS SYSTEM DEPRESSANTS; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; ETHANOL; GENE EXPRESSION REGULATION; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; METHYL-CPG-BINDING PROTEIN 2; METHYLATION; MICE; MICE, INBRED C57BL; NEURODEGENERATIVE DISEASES; NEURONS; TRANSCRIPTIONAL ACTIVATION;

EID: 84891368499     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2013.11.043     Document Type: Article

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