Pretreatment with antiasthmatic drug ibudilast ameliorates Aβ1-42-induced memory impairment and neurotoxicity in mice

Pharmacology Biochemistry and Behavior

Volumn 124, Issue , 2014, Pages 373-379

  Wang, Hao ^a   Mei, Zhen Lin ^a   Zhong, Kai Long ^a   Hu, Mei ^a   Long, Yan ^a   Miao, Ming Xing ^a   Li, Ning ^a   Yan, Tian Hua ^a   Hong, Hao ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Amyloid ; Ibudilast; Memory; Neurotoxicity

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; CASPASE 3; IBUDILAST; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN BCL 2; TUMOR NECROSIS FACTOR ALPHA; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); ANTIASTHMATIC AGENT; PEPTIDE FRAGMENT; PYRIDINE DERIVATIVE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVATION; EXPLORATORY BEHAVIOR; HIPPOCAMPUS; LATENT PERIOD; LEARNING DISORDER; MALE; MEMORY; MEMORY DISORDER; MORRIS WATER MAZE TEST; MOUSE; NEUROTOXICITY; NONHUMAN; OPEN FIELD TEST; PRIORITY JOURNAL; SPATIAL LEARNING; Y-MAZE TEST; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; ENZYMOLOGY; INSTITUTE FOR CANCER RESEARCH MOUSE; MEMORY DISORDERS; METABOLISM;

AMYLOID BETA-PEPTIDES; ANIMALS; ANTI-ASTHMATIC AGENTS; CASPASE 3; CEREBRAL CORTEX; HIPPOCAMPUS; MEMORY DISORDERS; MICE; MICE, INBRED ICR; PEPTIDE FRAGMENTS; PROTO-ONCOGENE PROTEINS C-BCL-2; PYRIDINES;

EID: 84905180317     PISSN: 00913057     EISSN: 18735177     Source Type: Journal    
DOI: 10.1016/j.pbb.2014.07.006     Document Type: Article

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