Leukotriene D4 induces cognitive impairment through enhancement of CysLT1R-mediated amyloid-β generation in mice

Neuropharmacology

Volumn 65, Issue , 2013, Pages 182-192

  Tang, Su Su ^a   Wang, Xiao Yun ^a   Hong, Hao ^a   Long, Yan ^a   Li, Yong Qi ^a   Xiang, Guo Qing ^a   Jiang, Li Ying ^a   Zhang, Han Ting ^b   Liu, Li Ping ^c   Miao, Ming Xing ^a   Hu, Mei ^a   Zhang, Ting Ting ^a   Hu, Wei ^c   Ji, Hui ^a   Ye, Feng Ying ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b WEST VIRGINIA UNIVERSITY   (United States)

^c ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

Alzheimer's disease; Amyloid peptides; Cognition; Cysteinyl leukotriene receptor 1; Leukotriene D4

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; GAMMA SECRETASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LEUKOTRIENE D4; PEPTIDOLEUKOTRIENE; PEPTIDOLEUKOTRIENE RECEPTOR 1; PRANLUKAST; SYNAPTOTAGMIN I; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AMNESIA; AMYLOIDOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; BRAIN NERVE CELL; CELL CULTURE; COGNITIVE DEFECT; CONTROLLED STUDY; ENZYME ACTIVITY; FATTY ACID ANALYSIS; HIPPOCAMPUS; IN VITRO STUDY; INTRACELLULAR SIGNALING; MALE; MAZE TEST; MEMORY; MEMORY DISORDER; MENTAL PERFORMANCE; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN METABOLISM; PROTEIN SECRETION; PROTEIN TARGETING; RAT;

AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CELLS, CULTURED; CEREBRAL CORTEX; COGNITION DISORDERS; HIPPOCAMPUS; INFLAMMATION MEDIATORS; INFUSIONS, INTRAVENTRICULAR; LEUKOTRIENE D4; MALE; MAZE LEARNING; MICE; MICE, INBRED ICR; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, LEUKOTRIENE;

EID: 84870924565     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.08.026     Document Type: Article

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