-
1
-
-
0025295908
-
Effect of propentofylline (HWA 285) on extracellular purines and excitatory amino acids in CA1 of rat hippocampus during transient ischaemia
-
Andine P., Rudolphi K.A., Fredholm B.B., Hagberg H. Effect of propentofylline (HWA 285) on extracellular purines and excitatory amino acids in CA1 of rat hippocampus during transient ischaemia. Br. J. Pharmacol. 100:1990;814-818.
-
(1990)
Br. J. Pharmacol.
, vol.100
, pp. 814-818
-
-
Andine, P.1
Rudolphi, K.A.2
Fredholm, B.B.3
Hagberg, H.4
-
2
-
-
0028118593
-
Modulation of intracellular formation of reactive oxygen intermediates in peritoneal macrophages and microglia/brain macrophages by propentofylline
-
Banati R.B., Schubert P., Rothe G., Gehrmann J., Rudolphi K., Valet G., Kreutzberg G.W. Modulation of intracellular formation of reactive oxygen intermediates in peritoneal macrophages and microglia/brain macrophages by propentofylline. J. Cereb. Blood Flow Metab. 14:1994;145-149.
-
(1994)
J. Cereb. Blood Flow Metab.
, vol.14
, pp. 145-149
-
-
Banati, R.B.1
Schubert, P.2
Rothe, G.3
Gehrmann, J.4
Rudolphi, K.5
Valet, G.6
Kreutzberg, G.W.7
-
3
-
-
0034839169
-
Cyclic AMP modulates the response of central nervous system glia to fibroblast growth factor-2 by redirecting signalling pathways
-
Bayatti N., Engele J. Cyclic AMP modulates the response of central nervous system glia to fibroblast growth factor-2 by redirecting signalling pathways. J. Neurochem. 78:2001;972-980.
-
(2001)
J. Neurochem.
, vol.78
, pp. 972-980
-
-
Bayatti, N.1
Engele, J.2
-
4
-
-
0028233494
-
Hydrogen peroxide mediates amyloid beta protein toxicity
-
Behl C., Davis J.B., Lesley R., Schubert D. Hydrogen peroxide mediates amyloid beta protein toxicity. Cell. 77:1994;817-827.
-
(1994)
Cell
, vol.77
, pp. 817-827
-
-
Behl, C.1
Davis, J.B.2
Lesley, R.3
Schubert, D.4
-
5
-
-
0029245289
-
A potential role for apoptosis in neurodegeneration and Alzheimer's disease
-
Cotman C.W., Anderson A.J. A potential role for apoptosis in neurodegeneration and Alzheimer's disease. Mol. Neurobiol. 10:1995;19-45.
-
(1995)
Mol. Neurobiol.
, vol.10
, pp. 19-45
-
-
Cotman, C.W.1
Anderson, A.J.2
-
6
-
-
0023869979
-
Propentofylline (HWA 285) protects hippocampal neurons of Mongolian gerbils against ischemic damage in the presence of an adenosine antagonist
-
DeLeo J., Schubert P., Kreutzberg G.W. Propentofylline (HWA 285) protects hippocampal neurons of Mongolian gerbils against ischemic damage in the presence of an adenosine antagonist. Neurosci. Lett. 84:1988;307-311.
-
(1988)
Neurosci. Lett.
, vol.84
, pp. 307-311
-
-
DeLeo, J.1
Schubert, P.2
Kreutzberg, G.W.3
-
7
-
-
0242466233
-
Endogenous and exogenous fibroblast growth factor 2 support survival of chick retinal neurons by control of neuronal bcl-x(L) and bcl-2 expression through a fibroblast growth factor receptor 1- and ERK-dependent pathway
-
Desire L., Courtois Y., Jeanny J.C. Endogenous and exogenous fibroblast growth factor 2 support survival of chick retinal neurons by control of neuronal bcl-x(L) and bcl-2 expression through a fibroblast growth factor receptor 1- and ERK-dependent pathway. J. Neurochem. 75:2000;151-163.
-
(2000)
J. Neurochem.
, vol.75
, pp. 151-163
-
-
Desire, L.1
Courtois, Y.2
Jeanny, J.C.3
-
8
-
-
0030808462
-
Aggregated amyloid-beta protein induces cortical neuronal apoptosis and concomitant "apoptotic" pattern of gene induction
-
Estus S., Tucker H.M., van-Rooyen C., Wright S., Brigham E.F., Wogulis M., Rydel R.E. Aggregated amyloid-beta protein induces cortical neuronal apoptosis and concomitant "apoptotic" pattern of gene induction. J. Neurosci. 17:1997;7736-7745.
-
(1997)
J. Neurosci.
, vol.17
, pp. 7736-7745
-
-
Estus, S.1
Tucker, H.M.2
Van-Rooyen, C.3
Wright, S.4
Brigham, E.F.5
Wogulis, M.6
Rydel, R.E.7
-
9
-
-
0027191973
-
Apoptosis mediated neurotoxicity induced by chronic application of beta amyloid fragment 25-35
-
Forloni G., Chiesa R., Smiroldo S., Verga L., Salmona M., Tagliavini F., Angeretti N. Apoptosis mediated neurotoxicity induced by chronic application of beta amyloid fragment 25-35. NeuroReport. 4:1993;523-526.
-
(1993)
NeuroReport
, vol.4
, pp. 523-526
-
-
Forloni, G.1
Chiesa, R.2
Smiroldo, S.3
Verga, L.4
Salmona, M.5
Tagliavini, F.6
Angeretti, N.7
-
10
-
-
0026623383
-
Further evidence that propentofylline(HWA 285) influences both adenosine receptors and adenosine transport
-
Fredholm B.B., Fastbom J., Kvanta A., Gerwins P., Parkinson F. Further evidence that propentofylline(HWA 285) influences both adenosine receptors and adenosine transport. Fundam. Clin. Pharmacol. 6:1992;99-111.
-
(1992)
Fundam. Clin. Pharmacol.
, vol.6
, pp. 99-111
-
-
Fredholm, B.B.1
Fastbom, J.2
Kvanta, A.3
Gerwins, P.4
Parkinson, F.5
-
11
-
-
0029031348
-
Apoptotic cell death induced by beta-amyloid 1-42 peptide is cell type dependent
-
Gschwind M., Huber G. Apoptotic cell death induced by beta-amyloid 1-42 peptide is cell type dependent. J. Neurochem. 65:1995;292-300.
-
(1995)
J. Neurochem.
, vol.65
, pp. 292-300
-
-
Gschwind, M.1
Huber, G.2
-
12
-
-
0033009194
-
Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: Central roles of superoxide production and caspase activation
-
Guo Q., Sebastian L., Sopher B.L., Miller M.W., Ware C.B., Martin G.M., Mattson M.P. Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: central roles of superoxide production and caspase activation. J. Neurochem. 72:1999;1019-1029.
-
(1999)
J. Neurochem.
, vol.72
, pp. 1019-1029
-
-
Guo, Q.1
Sebastian, L.2
Sopher, B.L.3
Miller, M.W.4
Ware, C.B.5
Martin, G.M.6
Mattson, M.P.7
-
13
-
-
0033120591
-
Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A
-
Harada H., Becknell B., Wilm M., Mann M., Huang L.J., Taylor S.S., Scott J.D., Korsmeyer S.J. Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A. Mol. Cell. 3:1999;413-422.
-
(1999)
Mol. Cell
, vol.3
, pp. 413-422
-
-
Harada, H.1
Becknell, B.2
Wilm, M.3
Mann, M.4
Huang, L.J.5
Taylor, S.S.6
Scott, J.D.7
Korsmeyer, S.J.8
-
14
-
-
0028169925
-
Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: Evidence that an initially deposited species is A beta 42(43)
-
Iwatsubo T., Odaka A., Suzuki N., Mizusawa H., Nukina N., Ihara Y. Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43). Neuron. 13:1994;45-53.
-
(1994)
Neuron
, vol.13
, pp. 45-53
-
-
Iwatsubo, T.1
Odaka, A.2
Suzuki, N.3
Mizusawa, H.4
Nukina, N.5
Ihara, Y.6
-
15
-
-
0032967259
-
Apoptotic cell death in neurons and glial cells: Implications for Alzheimer's disease
-
Kitamura Y., Taniguchi T., Shimohama S. Apoptotic cell death in neurons and glial cells: implications for Alzheimer's disease. Jpn. J. Pharmacol. 79:1999;1-5.
-
(1999)
Jpn. J. Pharmacol.
, vol.79
, pp. 1-5
-
-
Kitamura, Y.1
Taniguchi, T.2
Shimohama, S.3
-
16
-
-
0031578950
-
Effect of dibutyryl cAMP and several reagents on apoptosis in PC12 cells induced by a sialoglycopeptide from bovine brain
-
Kobayashi Y., Shinozawa T. Effect of dibutyryl cAMP and several reagents on apoptosis in PC12 cells induced by a sialoglycopeptide from bovine brain. Brain Res. 778:1997;309-317.
-
(1997)
Brain Res.
, vol.778
, pp. 309-317
-
-
Kobayashi, Y.1
Shinozawa, T.2
-
17
-
-
0034107999
-
Evaluation of neurotoxicity of Alzheimer's amyloid beta protein (beta42) in cultured hippocampal cells and its prevention by propentofylline
-
Koriyama Y., Yamazaki M., Chiba K., Mohri T. Evaluation of neurotoxicity of Alzheimer's amyloid beta protein (beta42) in cultured hippocampal cells and its prevention by propentofylline. Jpn. J. Pharmacol. 82:2000;301-306.
-
(2000)
Jpn. J. Pharmacol.
, vol.82
, pp. 301-306
-
-
Koriyama, Y.1
Yamazaki, M.2
Chiba, K.3
Mohri, T.4
-
18
-
-
0027257708
-
Apoptosis is induced by beta-amyloid in cultured central nervous system neurons
-
Loo D.T., Copani A., Pike C.J., Whittemore E.R., Walencewicz A.J., Cotman C.W. Apoptosis is induced by beta-amyloid in cultured central nervous system neurons. Proc. Natl. Acad. Sci. U. S. A. 90:1993;7951-7955.
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 7951-7955
-
-
Loo, D.T.1
Copani, A.2
Pike, C.J.3
Whittemore, E.R.4
Walencewicz, A.J.5
Cotman, C.W.6
-
20
-
-
0030879207
-
A 12-month, randomized, placebo-controlled trial of propentofylline (HWA 285) in patients with dementia according to DSM III-R. The European Propentofylline Study Group
-
Marcusson J., Rother M., Kittner B., Rossner M., Smith R.J., Babic T., Folnegovic-Smalc V., Moller H.J., Labs K.H. A 12-month, randomized, placebo-controlled trial of propentofylline (HWA 285) in patients with dementia according to DSM III-R. The European Propentofylline Study Group. Dement. Geriatr. Cogn. Disord. 8:1997;320-328.
-
(1997)
Dement. Geriatr. Cogn. Disord.
, vol.8
, pp. 320-328
-
-
Marcusson, J.1
Rother, M.2
Kittner, B.3
Rossner, M.4
Smith, R.J.5
Babic, T.6
Folnegovic-Smalc, V.7
Moller, H.J.8
Labs, K.H.9
-
21
-
-
0034923780
-
Molecular mechanisms of the decision between life and death: Regulation of apoptosis by apoptosis signal-regulating kinase 1
-
Matsuzawa A., Ichijo H. Molecular mechanisms of the decision between life and death: regulation of apoptosis by apoptosis signal-regulating kinase 1. J. Biochem. 130:2001;1-8.
-
(2001)
J. Biochem.
, vol.130
, pp. 1-8
-
-
Matsuzawa, A.1
Ichijo, H.2
-
22
-
-
0028348063
-
Phosphodiesterase inhibitory profile of some related xanthine derivatives pharmacologically active on the peripheral microcirculation
-
Meskini N., Nemoz G., Okyayuz-Baklouti I., Lagarde M., Prigent A.F. Phosphodiesterase inhibitory profile of some related xanthine derivatives pharmacologically active on the peripheral microcirculation. Biochem. Pharmacol. 47:1994;781-788.
-
(1994)
Biochem. Pharmacol.
, vol.47
, pp. 781-788
-
-
Meskini, N.1
Nemoz, G.2
Okyayuz-Baklouti, I.3
Lagarde, M.4
Prigent, A.F.5
-
23
-
-
0032802311
-
Caspase-3 expression by cerebellar granule neurons is regulated by calcium and cyclic AMP
-
Moran J., Itoh T., Reddy U.R., Chen M., Alnemri E.S., Pleasure D. Caspase-3 expression by cerebellar granule neurons is regulated by calcium and cyclic AMP. J. Neurochem. 73:1999;568-577.
-
(1999)
J. Neurochem.
, vol.73
, pp. 568-577
-
-
Moran, J.1
Itoh, T.2
Reddy, U.R.3
Chen, M.4
Alnemri, E.S.5
Pleasure, D.6
-
24
-
-
0021810477
-
In vitro and in vivo inhibitory effects of propentofylline on cyclic AMP phosphodiesterase activity
-
Nagata K., Ogawa T., Omosu M., Fujimoto K., Hayashi S. In vitro and in vivo inhibitory effects of propentofylline on cyclic AMP phosphodiesterase activity. Arzneimittel-Forschung. 35:1985;1034-1036.
-
(1985)
Arzneimittel-Forschung
, vol.35
, pp. 1034-1036
-
-
Nagata, K.1
Ogawa, T.2
Omosu, M.3
Fujimoto, K.4
Hayashi, S.5
-
25
-
-
0025786178
-
Characterization of the uptake of adenosine by cultured rat hippocampal cells and inhibition of the uptake by xanthine derivatives
-
Ohkubo T., Mitsumoto Y., Mohri T. Characterization of the uptake of adenosine by cultured rat hippocampal cells and inhibition of the uptake by xanthine derivatives. Neurosci. Lett. 13:1991;275-278.
-
(1991)
Neurosci. Lett.
, vol.13
, pp. 275-278
-
-
Ohkubo, T.1
Mitsumoto, Y.2
Mohri, T.3
-
26
-
-
0027166048
-
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
-
Oltvai Z.N., Milliman C.L., Korsmeyer S.J. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell. 74:1993;609-619.
-
(1993)
Cell
, vol.74
, pp. 609-619
-
-
Oltvai, Z.N.1
Milliman, C.L.2
Korsmeyer, S.J.3
-
27
-
-
0028106589
-
Antiischemic effects of propentofylline (HWA 285) against focal cerebral infarction in rats
-
Park C.K., Rudolphi K.A. Antiischemic effects of propentofylline (HWA 285) against focal cerebral infarction in rats. Neurosci. Lett. 178:1994;235-238.
-
(1994)
Neurosci. Lett.
, vol.178
, pp. 235-238
-
-
Park, C.K.1
Rudolphi, K.A.2
-
28
-
-
0034647616
-
cAMP delays beta-amyloid (25-35) induced cell death in rat cortical neurons
-
Parvathenani L.K., Calandra V., Roberts S.B., Posmantur R. cAMP delays beta-amyloid (25-35) induced cell death in rat cortical neurons. NeuroReport. 11:2000;2293-2297.
-
(2000)
NeuroReport
, vol.11
, pp. 2293-2297
-
-
Parvathenani, L.K.1
Calandra, V.2
Roberts, S.B.3
Posmantur, R.4
-
29
-
-
0025992417
-
In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity
-
Pike C.J., Walencewicz A.J., Glabe C.G., Cotman C.W. In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity. Brain Res. 563:1991;311-314.
-
(1991)
Brain Res.
, vol.563
, pp. 311-314
-
-
Pike, C.J.1
Walencewicz, A.J.2
Glabe, C.G.3
Cotman, C.W.4
-
30
-
-
9044243405
-
Protective effect of transforming growth factor-beta 1 on beta-amyloid neurotoxicity in rat hippocampal neurons
-
Prehn J.H., Bindokas V.P., Jordan J., Galindo M.F., Ghadge G.D., Roos R.P., Boise L.H., Thompson C.B., Krajewski S., Reed J.C., Miller R.J. Protective effect of transforming growth factor-beta 1 on beta-amyloid neurotoxicity in rat hippocampal neurons. Mol. Pharmacol. 49:1996;319-328.
-
(1996)
Mol. Pharmacol.
, vol.49
, pp. 319-328
-
-
Prehn, J.H.1
Bindokas, V.P.2
Jordan, J.3
Galindo, M.F.4
Ghadge, G.D.5
Roos, R.P.6
Boise, L.H.7
Thompson, C.B.8
Krajewski, S.9
Reed, J.C.10
Miller, R.J.11
-
31
-
-
0033600722
-
Insulin-like growth factor-I induces bcl-2 promoter through the transcription factor cAMP-response element-binding protein
-
Pugazhenthi S., Miller E., Sable C., Young P., Heidenreich K.A., Boxer L.M., Reusch J.E. Insulin-like growth factor-I induces bcl-2 promoter through the transcription factor cAMP-response element-binding protein. J. Biol. Chem. 274:1999;27529-27535.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 27529-27535
-
-
Pugazhenthi, S.1
Miller, E.2
Sable, C.3
Young, P.4
Heidenreich, K.A.5
Boxer, L.M.6
Reusch, J.E.7
-
32
-
-
0025533420
-
Propentofylline in adult-onset cognitive disorders: Double-blind, placebo-controlled, clinical, psychometric and brain mapping studies
-
Saletu B., Moller H.J., Grunberger J., Deutsch H., Rossner M. Propentofylline in adult-onset cognitive disorders: double-blind, placebo-controlled, clinical, psychometric and brain mapping studies. Neuropsychobiology. 24:1990;173-184.
-
(1990)
Neuropsychobiology
, vol.24
, pp. 173-184
-
-
Saletu, B.1
Moller, H.J.2
Grunberger, J.3
Deutsch, H.4
Rossner, M.5
-
33
-
-
0028172835
-
Modulation of nerve and glial function by adenosine - Role in the development of ischemic damage
-
Schubert P., Rudolphi K.A., Fredholm B.B., Nakamura Y. Modulation of nerve and glial function by adenosine - role in the development of ischemic damage. Int. J. Biochem. 26:1994;1227-1236.
-
(1994)
Int. J. Biochem.
, vol.26
, pp. 1227-1236
-
-
Schubert, P.1
Rudolphi, K.A.2
Fredholm, B.B.3
Nakamura, Y.4
-
34
-
-
0025350664
-
Stimulation of nerve growth factor synthesis/secretion by propentofylline in cultured mouse astroglial cells
-
Shinoda I., Furukawa Y., Furukawa S. Stimulation of nerve growth factor synthesis/secretion by propentofylline in cultured mouse astroglial cells. Biochem. Pharmacol. 39:1990;1813-1816.
-
(1990)
Biochem. Pharmacol.
, vol.39
, pp. 1813-1816
-
-
Shinoda, I.1
Furukawa, Y.2
Furukawa, S.3
-
35
-
-
0027427734
-
Toxic effect of a beta-amyloid peptide (beta 22-35) on the hippocampal neuron and its prevention
-
Takadera T., Sakura N., Mohri T., Hashimoto T. Toxic effect of a beta-amyloid peptide (beta 22-35) on the hippocampal neuron and its prevention. Neurosci. Lett. 161:1993;41-44.
-
(1993)
Neurosci. Lett.
, vol.161
, pp. 41-44
-
-
Takadera, T.1
Sakura, N.2
Mohri, T.3
Hashimoto, T.4
-
36
-
-
0028587336
-
APP717 missense mutation affects the ratio of amyloid beta protein species(Abeta1-42/43 and Abeta1-40) in familial Alzheimer's disease brain
-
Tamaoka A., Odaka A., Ishibashi Y., Usami M., Sahara N., Suzuki N., Nukina N., Mizusawa H., Shoji S., Kanazawa I., Mori H. APP717 missense mutation affects the ratio of amyloid beta protein species(Abeta1-42/43 and Abeta1-40) in familial Alzheimer's disease brain. J. Biol. Chem. 269:1994;32721-32724.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 32721-32724
-
-
Tamaoka, A.1
Odaka, A.2
Ishibashi, Y.3
Usami, M.4
Sahara, N.5
Suzuki, N.6
Nukina, N.7
Mizusawa, H.8
Shoji, S.9
Kanazawa, I.10
Mori, H.11
-
37
-
-
0035907325
-
Beta-amyloid-(1-42) impairs activity-dependent cAMP-response element-binding protein signaling in neurons at concentrations in which cell survival is not compromised
-
Tong L., Thornton P.L., Balazs R., Cotman C.W. Beta-amyloid-(1-42) impairs activity-dependent cAMP-response element-binding protein signaling in neurons at concentrations in which cell survival is not compromised. J. Biol. Chem. 276:2001;17301-17306.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 17301-17306
-
-
Tong, L.1
Thornton, P.L.2
Balazs, R.3
Cotman, C.W.4
-
38
-
-
0032524558
-
Propentofylline improves learning and memory deficits in rats induced by beta-amyloid protein-(1-40)
-
Yamada K., Tanaka T., Senzaki K., Kameyama T., Nabeshima T. Propentofylline improves learning and memory deficits in rats induced by beta-amyloid protein-(1-40). Eur. J. Pharmacol. 349:1998;15-22.
-
(1998)
Eur. J. Pharmacol.
, vol.349
, pp. 15-22
-
-
Yamada, K.1
Tanaka, T.2
Senzaki, K.3
Kameyama, T.4
Nabeshima, T.5
-
39
-
-
0028206341
-
BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax
-
Yin X.M., Oltvai Z.N., Korsmeyer S.J. BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax. Nature. 369:1994;321-323.
-
(1994)
Nature
, vol.369
, pp. 321-323
-
-
Yin, X.M.1
Oltvai, Z.N.2
Korsmeyer, S.J.3
|