Ibudilast attenuates astrocyte apoptosis via cyclic GMP signalling pathway in an in vitro reperfusion model

British Journal of Pharmacology

Volumn 133, Issue 6, 2001, Pages 841-848

  Takuma, K ^a   Lee, E ^a   Enomoto, R ^a   Mori, K ^a   Baba, A ^b   Matsuda, T ^b  

^a KOBE GAKUIN UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

Apoptosis; Astrocyte; Caspase 3; Cyclic GMP; Cytochrome c release; Ibudilast

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CASPASE 3; CYCLIC AMP; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE INHIBITOR; CYTOCHROME C; DIBUTYRYL CYCLIC GMP; DIPYRIDAMOLE; HYDROGEN PEROXIDE; IBUDILAST; KT 5720; KT 5823; LEUKOTRIENE RECEPTOR BLOCKING AGENT; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PENTOXIFYLLINE; PHOSPHODIESTERASE INHIBITOR; PROTEIN KINASE INHIBITOR; THEOPHYLLINE; TOMELUKAST; VINPOCETINE; ZAPRINAST;

ANIMAL CELL; APOPTOSIS; ARTICLE; ASTHMA; ASTROCYTE; CEREBROVASCULAR DISEASE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFECT; DRUG INDICATION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; SIGNAL TRANSDUCTION;

EID: 0034881169     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704146     Document Type: Article

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