-
1
-
-
84979948588
-
A sarcoma of the fowl transmissible by an agent separable from the tumor cells
-
Rous, P. (1911). A sarcoma of the fowl transmissible by an agent separable from the tumor cells. J Exp Med, 13, 397-411.
-
(1911)
J Exp Med
, vol.13
, pp. 397-411
-
-
Rous, P.1
-
2
-
-
0014933756
-
Rous sarcoma virus: A function required for the maintenance of the transformed state
-
Martin, G. S. (1970). Rous sarcoma virus: a function required for the maintenance of the transformed state. Nature, 227, 1021-1023.
-
(1970)
Nature
, vol.227
, pp. 1021-1023
-
-
Martin, G.S.1
-
3
-
-
0017250977
-
DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA
-
Stehelin, D., Varmus, H. E., Bishop, J. M., & Vogt, P. K. (1976). DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA. Nature, 260, 170-173.
-
(1976)
Nature
, vol.260
, pp. 170-173
-
-
Stehelin, D.1
Varmus, H.E.2
Bishop, J.M.3
Vogt, P.K.4
-
4
-
-
0005953097
-
Protein kinase activity associated with the avian sarcoma virus src gene product
-
DOI 10.1073/pnas.75.4.2021
-
Collett, M. S., & Erikson, R. L. (1978). Protein kinase activity associated with the avian sarcoma virus src gene product. Proc Natl Acad Sci U S A, 75, 2021-2024. (Pubitemid 8335476)
-
(1978)
Proceedings of the National Academy of Sciences of the United States of America
, vol.75
, Issue.4
, pp. 2021-2024
-
-
Collett, M.S.1
Erikson, R.L.2
-
5
-
-
0000109995
-
Transforming gene product of Rous sarcoma virus phosphorylates tyrosine
-
Hunter, T., & Sefton, B. M. (1980). Transforming gene product of Rous sarcoma virus phosphorylates tyrosine. Proc Natl Acad Sci U S A, 77, 1311-1315. (Pubitemid 10072278)
-
(1980)
Proceedings of the National Academy of Sciences of the United States of America
, vol.77
, Issue.3 I
, pp. 1311-1315
-
-
Hunter, T.1
Sefton, B.M.2
-
6
-
-
0035374609
-
The hunting of the Src
-
Martin, G. S. (2001). The hunting of the Src. Nat Rev Mol Cell Biol, 2, 467-475.
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 467-475
-
-
Martin, G.S.1
-
8
-
-
0031452274
-
Structures of Src-family tyrosine kinases
-
DOI 10.1016/S0959-440X(97)80146-7
-
Sicheri, F., & Kuriyan, J. (1997). Structures of Src-family tyrosine kinases. Curr Opin Struct Biol, 7, 777-785. (Pubitemid 28025103)
-
(1997)
Current Opinion in Structural Biology
, vol.7
, Issue.6
, pp. 777-785
-
-
Sicheri, F.1
Kuriyan, J.2
-
9
-
-
77956621729
-
Myristoylation and membrane binding regulate c-Src stability and kinase activity
-
Patwardhan, P., & Resh, M. D. (2010). Myristoylation and membrane binding regulate c-Src stability and kinase activity. Mol Cell Biol, 30, 4094-4107.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 4094-4107
-
-
Patwardhan, P.1
Resh, M.D.2
-
10
-
-
0028301606
-
Dual myristylation and palmitylation of Src family member p59fyn affects subcellular localization
-
Alland, L., Peseckis, S. M., Atherton, R. E., Berthiaume, L., & Resh, M. D. (1994). Dual myristylation and palmitylation of Src family member p59fyn affects subcellular localization. J Biol Chem, 269, 16701-16705.
-
(1994)
J Biol Chem
, vol.269
, pp. 16701-16705
-
-
Alland, L.1
Peseckis, S.M.2
Atherton, R.E.3
Berthiaume, L.4
Resh, M.D.5
-
11
-
-
0023860445
-
Sequence similarity of phospholipase C with the non-catalytic region of src
-
DOI 10.1038/332269a0
-
Stahl, M. L., Ferenz, C. R., Kelleher, K. L., Kriz, R. W., & Knopf, J. L. (1988). Sequence similarity of phospholipase C with the non-catalytic region of src. Nature, 332, 269-272. (Pubitemid 18076659)
-
(1988)
Nature
, vol.332
, Issue.6161
, pp. 269-272
-
-
Stahl, M.L.1
Ferenz, C.R.2
Kelleher, K.L.3
Kriz, R.W.4
Knopf, J.L.5
-
12
-
-
0028895654
-
Modular binding domains in signal transduction proteins
-
Cohen, G. B., Ren, R., & Baltimore, D. (1995). Modular binding domains in signal transduction proteins. Cell, 80, 237-248.
-
(1995)
Cell
, vol.80
, pp. 237-248
-
-
Cohen, G.B.1
Ren, R.2
Baltimore, D.3
-
13
-
-
0031017838
-
Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement
-
DOI 10.1038/385650a0
-
Moarefi, I., LaFevre-Bernt, M., Sicheri, F., et al. (1997). Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement. Nature, 385, 650-653. (Pubitemid 27087580)
-
(1997)
Nature
, vol.385
, Issue.6617
, pp. 650-653
-
-
Moarefi, I.1
LaFevre-Bernt, M.2
Sicheri, F.3
Huse, M.4
Lee, C.-H.5
Kuriyan, J.6
Miller, W.T.7
-
14
-
-
0025119824
-
Src homology region 2 domains direct protein-protein interactions in signal transduction
-
Moran, M. F., Koch, C. A., Anderson, D., et al. (1990). Src homology region 2 domains direct protein-protein interactions in signal transduction. Proc Natl Acad Sci U S A, 87, 8622-8626.
-
(1990)
Proc Natl Acad Sci U S a
, vol.87
, pp. 8622-8626
-
-
Moran, M.F.1
Koch, C.A.2
Anderson, D.3
-
15
-
-
0023885305
-
The protein kinase family: Conserved features and deduced phylogeny of the catalytic domains
-
Hanks, S. K., Quinn, A. M., & Hunter, T. (1988). The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. Science, 241, 42-52.
-
(1988)
Science
, vol.241
, pp. 42-52
-
-
Hanks, S.K.1
Quinn, A.M.2
Hunter, T.3
-
16
-
-
38349014380
-
Src family kinases: Regulation of their activities, levels and identification of new pathways
-
Ingley, E. (2008). Src family kinases: regulation of their activities, levels and identification of new pathways. Biochim Biophys Acta, 1784, 56-65.
-
(2008)
Biochim Biophys Acta
, vol.1784
, pp. 56-65
-
-
Ingley, E.1
-
17
-
-
0022559078
-
527 is phosphorylated in pp60(c-src): Implications for regulation
-
Cooper, J. A., Gould, K. L., Cartwright, C. A., & Hunter, T. (1986). Tyr527 is phosphorylated in pp 60c-src: implications for regulation. Science, 231, 1431-1434. (Pubitemid 16046654)
-
(1986)
Science
, vol.231
, Issue.4744
, pp. 1431-1434
-
-
Cooper, J.A.1
Gould, K.L.2
Cartwright, C.A.3
Hunter, T.4
-
18
-
-
0023649672
-
Activation and suppression of pp 60c-src transforming ability bymutation of its primary sites of tyrosine phosphorylation
-
Kmiecik, T. E., & Shalloway, D. (1987). Activation and suppression of pp 60c-src transforming ability bymutation of its primary sites of tyrosine phosphorylation. Cell, 49, 65-73.
-
(1987)
Cell
, vol.49
, pp. 65-73
-
-
Kmiecik, T.E.1
Shalloway, D.2
-
19
-
-
0031025991
-
Three-dimensional structure of the tyrosine kinase c-Src
-
DOI 10.1038/385595a0
-
Xu, W., Harrison, S. C., & Eck, M. J. (1997). Three-dimensional structure of the tyrosine kinase c-Src. Nature, 385, 595-602. (Pubitemid 27087566)
-
(1997)
Nature
, vol.385
, Issue.6617
, pp. 595-602
-
-
Xu, W.1
Harrison, S.C.2
Eck, M.J.3
-
20
-
-
0026355723
-
CSK: A protein-tyrosine kinase involved in regulation of src family kinases
-
Okada, M., Nada, S., Yamanashi, Y., Yamamoto, T., & Nakagawa, H. (1991). CSK: a protein-tyrosine kinase involved in regulation of src family kinases. J Biol Chem, 266, 24249-24252. (Pubitemid 21908933)
-
(1991)
Journal of Biological Chemistry
, vol.266
, Issue.36
, pp. 24249-24252
-
-
Okada, M.1
Nada, S.2
Yamanashi, Y.3
Yamamoto, T.4
Nakagawa, H.5
-
21
-
-
32144460477
-
C-terminal Src kinase (CSK) and CSK-homologous kinase (CHK) - Endogenous negative regulators of Src-family protein kinases
-
DOI 10.1080/08977190500178877, PII J50771704863817
-
Chong, Y. P., Mulhern, T. D., & Cheng, H. C. (2005). C-terminal Src kinase (CSK) and CSK-homologous kinase (CHK) - endogenous negative regulators of Src-family protein kinases. Growth Factors, 23, 233-244. (Pubitemid 43203054)
-
(2005)
Growth Factors
, vol.23
, Issue.3
, pp. 233-244
-
-
Chong, Y.-P.1
Mulhern, T.D.2
Cheng, H.-C.3
-
22
-
-
70349758510
-
Src kinases as therapeutic targets for cancer
-
Kim, L. C., Song, L., & Haura, E. B. (2009). Src kinases as therapeutic targets for cancer. Nat Rev Clin Oncol, 6, 587-595.
-
(2009)
Nat Rev Clin Oncol
, vol.6
, pp. 587-595
-
-
Kim, L.C.1
Song, L.2
Haura, E.B.3
-
23
-
-
0032932248
-
Activating SRC mutation in a subset of advanced human colon cancers
-
DOI 10.1038/5971
-
Irby, R. B., Mao, W., Coppola, D., et al. (1999). Activating SRC mutation in a subset of advanced human colon cancers. Nat Genet, 21, 187-190. (Pubitemid 29070364)
-
(1999)
Nature Genetics
, vol.21
, Issue.2
, pp. 187-190
-
-
Irby, R.B.1
Mao, W.2
Coppola, D.3
Kang, J.4
Loubeau, J.M.5
Trudeau, W.6
Karl, R.7
Fujita, D.J.8
Jove, R.9
Yeatman, T.J.10
-
24
-
-
0000441561
-
Role of c- Src tyrosine kinase in EGF-induced mitogenesis
-
Belsches, A. P., Haskell, M. D., & Parsons, S. J. (1997). Role of c- Src tyrosine kinase in EGF-induced mitogenesis. Front Biosci, 2, d501-d518.
-
(1997)
Front Biosci
, vol.2
-
-
Belsches, A.P.1
Haskell, M.D.2
Parsons, S.J.3
-
25
-
-
0030898418
-
Src family protein tyrosine kinases: Cooperating with growth factor and adhesion signaling pathways
-
DOI 10.1016/S0955-0674(97)80062-2
-
Parsons, J. T., & Parsons, S. J. (1997). Src family protein tyrosine kinases: cooperating with growth factor and adhesion signaling pathways. Curr Opin Cell Biol, 9, 187-192. (Pubitemid 27135986)
-
(1997)
Current Opinion in Cell Biology
, vol.9
, Issue.2
, pp. 187-192
-
-
Parsons, J.T.1
Parsons, S.J.2
-
26
-
-
0032532096
-
Lck associates with and is activated by kit in a small cell lung cancer cell line: Inhibition of SCF-mediated growth by the Src family kinase inhibitor PP1
-
Krystal, G. W., DeBerry, C. S., Linnekin, D., & Litz, J. (1998). Lck associates with and is activated by Kit in a small cell lung cancer cell line: inhibition of SCF-mediated growth by the Src family kinase inhibitor PP1. Cancer Res, 58, 4660-4666. (Pubitemid 28480632)
-
(1998)
Cancer Research
, vol.58
, Issue.20
, pp. 4660-4666
-
-
Krystal, G.W.1
DeBerry, C.S.2
Linnekin, D.3
Litz, J.4
-
27
-
-
0032933797
-
c-Src, receptor tyrosine kinases, and human cancer
-
Biscardi, J. S., Tice, D. A., & Parsons, S. J. (1999). c-Src, receptor tyrosine kinases, and human cancer. Adv Cancer Res, 76, 61-119. (Pubitemid 29190881)
-
(1999)
Advances in Cancer Research
, vol.76
, pp. 61-119
-
-
Biscardi, J.S.1
Tice, D.A.2
Parsons, S.J.3
-
28
-
-
0034627767
-
Src family tyrosine kinases and growth factor signaling
-
DOI 10.1006/excr.1999.4732
-
Abram, C. L., & Courtneidge, S. A. (2000). Src family tyrosine kinases and growth factor signaling. Exp Cell Res, 254, 1-13. (Pubitemid 30066726)
-
(2000)
Experimental Cell Research
, vol.254
, Issue.1
, pp. 1-13
-
-
Abram, C.L.1
Courtneidge, S.A.2
-
29
-
-
0033739784
-
Colony-stimulating factor-1 receptor utilizes multiple signaling pathways to induce cyclin D2 expression
-
Dey, A., She, H., Kim, L., et al. (2000). Colony-stimulating factor-1 receptor utilizes multiple signaling pathways to induce cyclin D2 expression. Mol Biol Cell, 11, 3835-3848.
-
(2000)
Mol Biol Cell
, vol.11
, pp. 3835-3848
-
-
Dey, A.1
She, H.2
Kim, L.3
-
30
-
-
1642458352
-
c-Kit-Mediated Overlapping and Unique Functional and Biochemical Outcomes via Diverse Signaling Pathways
-
DOI 10.1128/MCB.24.3.1401-1410.2004
-
Hong, L., Munugalavadla, V., & Kapur, R. (2004). c-Kit-mediated overlapping and unique functional and biochemical outcomes via diverse signaling pathways. Mol Cell Biol, 24, 1401-1410. (Pubitemid 38112199)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.3
, pp. 1401-1410
-
-
Hong, L.1
Munugalavadla, V.2
Kapur, R.3
-
31
-
-
0035370294
-
Src-class kinases act within the agrin/musk pathway to regulate acetylcholine receptor phosphorylation, cytoskeletal anchoring, and clustering
-
Mohamed, A. S., Rivas-Plata, K. A., Kraas, J. R., Saleh, S. M., & Swope, S. L. (2001). Src-class kinases act within the agrin/MuSK pathway to regulate acetylcholine receptor phosphorylation, cytoskeletal anchoring, and clustering. J Neurosci, 21, 3806-3818. (Pubitemid 32466473)
-
(2001)
Journal of Neuroscience
, vol.21
, Issue.11
, pp. 3806-3818
-
-
Mohamed, A.S.1
Rivas-Plata, K.A.2
Kraas, J.R.3
Saleh, S.M.4
Swope, S.L.5
-
32
-
-
12244289684
-
Src family kinases and nitric oxide production are required for hepatocyte growth factor-stimulated endothelial cell growth
-
DOI 10.1016/S0021-9150(02)00384-2, PII S0021915002003842
-
Maejima, Y., Ueba, H., Kuroki, M., et al. (2003). Src family kinases and nitric oxide production are required for hepatocyte growth factorstimulated endothelial cell growth. Atherosclerosis, 167, 89-95. (Pubitemid 36255639)
-
(2003)
Atherosclerosis
, vol.167
, Issue.1
, pp. 89-95
-
-
Maejima, Y.1
Ueba, H.2
Kuroki, M.3
Yasu, T.4
Hashimoto, S.5
Nabata, A.6
Kobayashi, N.7
Ikeda, N.8
Saito, M.9
Kawakami, M.10
-
33
-
-
7944237784
-
The interplay between Src family kinases and receptor tyrosine kinases
-
DOI 10.1038/sj.onc.1208079
-
Bromann, P. A., Korkaya, H., & Courtneidge, S. A. (2004). The interplay between Src family kinases and receptor tyrosine kinases. Oncogene, 23, 7957-7968. (Pubitemid 39468854)
-
(2004)
Oncogene
, vol.23
, Issue.48 REV. ISS. 7
, pp. 7957-7968
-
-
Bromann, P.A.1
Korkaya, H.2
Courtneidge, S.A.3
-
34
-
-
36248973171
-
The role of Src in prostate cancer
-
Fizazi, K. (2007). The role of Src in prostate cancer. Ann Oncol, 18, 1765-1773.
-
(2007)
Ann Oncol
, vol.18
, pp. 1765-1773
-
-
Fizazi, K.1
-
35
-
-
0842347483
-
Lyn Is a Target Gene for Prostate Cancer: Sequence-Based Inhibition Induces Regression of Human Tumor Xenografts
-
DOI 10.1158/0008-5472.CAN-03-2420
-
Goldenberg-Furmanov, M., Stein, I., Pikarsky, E., et al. (2004). Lyn is a target gene for prostate cancer: sequence-based inhibition induces regression of human tumor xenografts. Cancer Res, 64, 1058-1066. (Pubitemid 38176910)
-
(2004)
Cancer Research
, vol.64
, Issue.3
, pp. 1058-1066
-
-
Goldenberg-Furmanov, M.1
Stein, I.2
Pikarsky, E.3
Rubin, H.4
Kasem, S.5
Wygoda, M.6
Weinstein, I.7
Reuveni, H.8
Ben-Sasson, S.A.9
-
36
-
-
58149174199
-
FYN is overexpressed in human prostate cancer
-
Posadas, E. M., Al-Ahmadie, H., Robinson, V. L., et al. (2009). FYN is overexpressed in human prostate cancer. BJU Int, 103, 171- 177.
-
(2009)
BJU Int
, vol.103
, pp. 171-177
-
-
Posadas, E.M.1
Al-Ahmadie, H.2
Robinson, V.L.3
-
37
-
-
66149164441
-
SRC family kinase activity is upregulated in hormone-refractory prostate cancer
-
Tatarov, O., Mitchell, T. J., Seywright, M., Leung, H. Y., Brunton, V. G., & Edwards, J. (2009). SRC family kinase activity is upregulated in hormone-refractory prostate cancer. Clin Cancer Res, 15, 3540-3549.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 3540-3549
-
-
Tatarov, O.1
Mitchell, T.J.2
Seywright, M.3
Leung, H.Y.4
Brunton, V.G.5
Edwards, J.6
-
38
-
-
79955632219
-
Differential transformation capacity of Src family kinases during the initiation of prostate cancer
-
Cai, H., Smith, D. A., Memarzadeh, S., Lowell, C. A., Cooper, J. A., & Witte, O. N. (2011). Differential transformation capacity of Src family kinases during the initiation of prostate cancer. Proc Natl Acad Sci U S A, 108, 6579-6584.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 6579-6584
-
-
Cai, H.1
Smith, D.A.2
Memarzadeh, S.3
Lowell, C.A.4
Cooper, J.A.5
Witte, O.N.6
-
39
-
-
79551564924
-
Invasive prostate carcinoma driven by c-Src and androgen receptor synergy
-
Cai, H., Babic, I., Wei, X., Huang, J., & Witte, O. N. (2011). Invasive prostate carcinoma driven by c-Src and androgen receptor synergy. Cancer Res, 71, 862-872.
-
(2011)
Cancer Res
, vol.71
, pp. 862-872
-
-
Cai, H.1
Babic, I.2
Wei, X.3
Huang, J.4
Witte, O.N.5
-
40
-
-
44849134528
-
Targeting SRC family kinases inhibits growth and lymph node metastases of prostate cancer in an orthotopic nude mouse model
-
Park, S. I., Zhang, J., Phillips, K. A., et al. (2008). Targeting SRC family kinases inhibits growth and lymph node metastases of prostate cancer in an orthotopic nude mouse model. Cancer Res, 68, 3323-3333.
-
(2008)
Cancer Res
, vol.68
, pp. 3323-3333
-
-
Park, S.I.1
Zhang, J.2
Phillips, K.A.3
-
41
-
-
54549086723
-
Src family kinase oncogenic potential and pathways in prostate cancer as revealed by AZD0530
-
Chang, Y. M., Bai, L., Liu, S., Yang, J. C., Kung, H. J., & Evans, C. P. (2008). Src family kinase oncogenic potential and pathways in prostate cancer as revealed by AZD0530. Oncogene, 27, 6365-6375.
-
(2008)
Oncogene
, vol.27
, pp. 6365-6375
-
-
Chang, Y.M.1
Bai, L.2
Liu, S.3
Yang, J.C.4
Kung, H.J.5
Evans, C.P.6
-
42
-
-
18844444774
-
HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas
-
DOI 10.1038/sj.onc.1208513
-
Gray, M. J., Zhang, J., Ellis, L. M., et al. (2005). HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas. Oncogene, 24, 3110-3120. (Pubitemid 40695080)
-
(2005)
Oncogene
, vol.24
, Issue.19
, pp. 3110-3120
-
-
Gray, M.J.1
Zhang, J.2
Ellis, L.M.3
Semenza, G.L.4
Evans, D.B.5
Watowich, S.S.6
Gallick, G.E.7
-
43
-
-
85047695527
-
Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis
-
DOI 10.1038/sj/onc/1205260
-
Niu, G., Wright, K. L., Huang, M., et al. (2002). Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis. Oncogene, 21, 2000-2008. (Pubitemid 34270888)
-
(2002)
Oncogene
, vol.21
, Issue.13
, pp. 2000-2008
-
-
Niu, G.1
Wright, K.L.2
Huang, M.3
Song, L.4
Haura, E.5
Turkson, J.6
Zhang, S.7
Wang, T.8
Sinibaldi, D.9
Coppola, D.10
Heller, R.11
Ellis, L.M.12
Karras, J.13
Bromberg, J.14
Pardoll, D.15
Jove, R.16
Yu, H.17
-
44
-
-
23844530826
-
Expression and activity of Src regulate interleukin-8 expression in pancreatic adenocarcinoma cells: Implications for angiogenesis
-
DOI 10.1158/0008-5472.CAN-04-3858
-
Trevino, J. G., Summy, J. M., Gray, M. J., et al. (2005). Expression and activity of SRC regulate interleukin-8 expression in pancreatic adenocarcinoma cells: implications for angiogenesis. Cancer Res, 65, 7214-7222. (Pubitemid 41161252)
-
(2005)
Cancer Research
, vol.65
, Issue.16
, pp. 7214-7222
-
-
Trevino, J.G.1
Summy, J.M.2
Gray, M.J.3
Nilsson, M.B.4
Lesslie, D.P.5
Baker, C.H.6
Gallick, G.E.7
-
45
-
-
84890555121
-
Prostate cancer progression after androgen deprivation therapy: Mechanisms of castrate resistance and novel therapeutic approaches
-
Karantanos, T., Corn, P. G., Thompson, T. C. (2013). Prostate cancer progression after androgen deprivation therapy: mechanisms of castrate resistance and novel therapeutic approaches. Oncogene
-
(2013)
Oncogene
-
-
Karantanos, T.1
Corn, P.G.2
Thompson, T.C.3
-
46
-
-
0034675994
-
Steroid-induced androgen receptor-oestradiol receptor beta-Src complex triggers prostate cancer cell proliferation
-
Migliaccio, A., Castoria, G., Di, D. M., et al. (2000). Steroid-induced androgen receptor-oestradiol receptor beta-Src complex triggers prostate cancer cell proliferation. EMBO J, 19, 5406-5417.
-
(2000)
EMBO J
, vol.19
, pp. 5406-5417
-
-
Migliaccio, A.1
Castoria, G.2
Di, D.M.3
-
47
-
-
0038318941
-
Sex steroid hormones act as growth factors
-
DOI 10.1016/S0960-0760(02)00264-9
-
Migliaccio, A., Castoria, G., Di, D. M., et al. (2002). Sex steroid hormones act as growth factors. J Steroid Biochem Mol Biol, 83, 31-35. (Pubitemid 37040639)
-
(2002)
Journal of Steroid Biochemistry and Molecular Biology
, vol.83
, Issue.1-5
, pp. 31-35
-
-
Migliaccio, A.1
Castoria, G.2
Di, D.M.3
De Falco, A.4
Bilancio, A.5
Lombardi, M.6
Bottero, D.7
Varricchio, L.8
Nanayakkara, M.9
Rotondi, A.10
Auricchio, F.11
-
48
-
-
27544435790
-
The role of DOC-2/DAB2 in modulating androgen receptor-mediated cell growth via the nongenomic c-Src-mediated pathway in normal prostatic epithelium and cancer
-
DOI 10.1158/0008-5472.CAN-05-1481
-
Zhoul, J., Hernandez, G., Tu, S. W., Huang, C. L., Tseng, C. P., & Hsieh, J. T. (2005). The role of DOC-2/DAB2 in modulating androgen receptor-mediated cell growth via the nongenomic c-Src-mediated pathway in normal prostatic epithelium and cancer. Cancer Res, 65, 9906-9913. (Pubitemid 41541471)
-
(2005)
Cancer Research
, vol.65
, Issue.21
, pp. 9906-9913
-
-
Zhoul, J.1
Hernandez, G.2
Tu, S.-W.3
Huang, C.-L.4
Tseng, C.-P.5
Hsieh, J.-T.6
-
49
-
-
33644675811
-
Biology of progressive, castration-resistant prostate cancer: Directed therapies targeting the androgen-receptor signaling axis
-
DOI 10.1200/JCO.2005.03.4777
-
Scher, H. I., & Sawyers, C. L. (2005). Biology of progressive, castration-resistant prostate cancer: directed therapies targeting the androgen-receptor signaling axis. J Clin Oncol, 23, 8253-8261. (Pubitemid 46211563)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.32
, pp. 8253-8261
-
-
Scher, H.I.1
Sawyers, C.L.2
-
50
-
-
70349395222
-
Anti-androgens and androgen-depleting therapies in prostate cancer: New agents for an established target
-
Chen, Y., Clegg, N. J., & Scher, H. I. (2009). Anti-androgens and androgen-depleting therapies in prostate cancer: new agents for an established target. Lancet Oncol, 10, 981-991.
-
(2009)
Lancet Oncol
, vol.10
, pp. 981-991
-
-
Chen, Y.1
Clegg, N.J.2
Scher, H.I.3
-
51
-
-
33749445413
-
Regulation of androgen receptor activity by tyrosine phosphorylation
-
DOI 10.1016/j.ccr.2006.08.021, PII S1535610806002777
-
Guo, Z., Dai, B., Jiang, T., et al. (2006). Regulation of androgen receptor activity by tyrosine phosphorylation. Cancer Cell, 10, 309-319. (Pubitemid 44512189)
-
(2006)
Cancer Cell
, vol.10
, Issue.4
, pp. 309-319
-
-
Guo, Z.1
Dai, B.2
Jiang, T.3
Xu, K.4
Xie, Y.5
Kim, O.6
Nesheiwat, I.7
Kong, X.8
Melamed, J.9
Handratta, V.D.10
Njar, V.C.O.11
Brodie, A.M.H.12
Yu, L.-R.13
Veenstra, T.D.14
Chen, H.15
Qiu, Y.16
-
52
-
-
44849102368
-
Src kinase potentiates androgen receptor transactivation function and invasion of androgen-independent prostate cancer C4-2 cells
-
DOI 10.1038/sj.onc.1211016, PII 1211016
-
Asim, M., Siddiqui, I. A., Hafeez, B. B., Baniahmad, A., & Mukhtar, H. (2008). Src kinase potentiates androgen receptor transactivation function and invasion of androgen-independent prostate cancer C4-2 cells. Oncogene, 27, 3596-3604. (Pubitemid 351793796)
-
(2008)
Oncogene
, vol.27
, Issue.25
, pp. 3596-3604
-
-
Asim, M.1
Siddiqui, I.A.2
Hafeez, B.B.3
Baniahmad, A.4
Mukhtar, H.5
-
53
-
-
0035204477
-
Neuropeptide-induced androgen independence in prostate cancer cells: Roles of nonreceptor tyrosine kinases Etk/Bmx, Src, and focal adhesion kinase
-
DOI 10.1128/MCB.21.24.8385-8397.2001
-
Lee, L. F., Guan, J., Qiu, Y., & Kung, H. J. (2001). Neuropeptide-induced androgen independence in prostate cancer cells: roles of nonreceptor tyrosine kinases Etk/Bmx, Src, and focal adhesion kinase. Mol Cell Biol, 21, 8385-8397. (Pubitemid 33108599)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.24
, pp. 8385-8397
-
-
Lee, L.-F.1
Guan, J.2
Qiu, Y.3
Kung, H.-J.4
-
54
-
-
33751267275
-
Inappropriate activation of the androgen receptor by nonsteroids: Involvement of the Src kinase pathway and its therapeutic implications
-
DOI 10.1158/0008-5472.CAN-06-2582
-
Desai, S. J., Ma, A. H., Tepper, C. G., Chen, H. W., & Kung, H. J. (2006). Inappropriate activation of the androgen receptor by nonsteroids: involvement of the Src kinase pathway and its therapeutic implications. Cancer Res, 66, 10449-10459. (Pubitemid 44799766)
-
(2006)
Cancer Research
, vol.66
, Issue.21
, pp. 10449-10459
-
-
Desai, S.J.1
Ma, A.-H.2
Tepper, C.G.3
Chen, H.-W.4
Kung, H.-J.5
-
55
-
-
0032532688
-
Interleukin-6 regulates prostate-specific protein expression in prostate carcinoma cells by activation of the androgen receptor
-
Hobisch, A., Eder, I. E., Putz, T., et al. (1998). Interleukin-6 regulates prostate-specific protein expression in prostate carcinoma cells by activation of the androgen receptor. Cancer Res, 58, 4640-4645. (Pubitemid 28480629)
-
(1998)
Cancer Research
, vol.58
, Issue.20
, pp. 4640-4645
-
-
Hobisch, A.1
Eder, I.E.2
Putz, T.3
Horninger, W.4
Bartsch, G.5
Klocker, H.6
Culig, Z.7
-
56
-
-
1842434391
-
Interleukin-8 confers androgen-independent growth and migration of LNCaP: Differential effects of tyrosine kinases Src and FAK
-
DOI 10.1038/sj.onc.1207344
-
Lee, L. F., Louie, M. C., Desai, S. J., et al. (2004). Interleukin-8 confers androgen-independent growth and migration of LNCaP: differential effects of tyrosine kinases Src and FAK. Oncogene, 23, 2197-2205. (Pubitemid 38482534)
-
(2004)
Oncogene
, vol.23
, Issue.12
, pp. 2197-2205
-
-
Lee, L.-F.1
Louie, M.C.2
Desai, S.J.3
Yang, J.4
Chen, H.-W.5
Evans, C.P.6
Kung, H.-J.7
-
57
-
-
79951796016
-
Associations of saposin C, Src, and androgen receptor upregulate the expression and function of androgen receptor in human prostate cancer cells
-
Ding, Y., Wang, X., Xu, A., et al. (2011). Associations of saposin C, Src, and androgen receptor upregulate the expression and function of androgen receptor in human prostate cancer cells. J Cell Biochem, 112, 818-828.
-
(2011)
J Cell Biochem
, vol.112
, pp. 818-828
-
-
Ding, Y.1
Wang, X.2
Xu, A.3
-
58
-
-
80054796743
-
Ligand-dependent corepressor acts as a novel androgen receptor corepressor, inhibits prostate cancer growth, and is functionally inactivated by the Src protein kinase
-
Asim, M., Hafeez, B. B., Siddiqui, I. A., et al. (2011). Ligand-dependent corepressor acts as a novel androgen receptor corepressor, inhibits prostate cancer growth, and is functionally inactivated by the Src protein kinase. J Biol Chem, 286, 37108-37117.
-
(2011)
J Biol Chem
, vol.286
, pp. 37108-37117
-
-
Asim, M.1
Hafeez, B.B.2
Siddiqui, I.A.3
-
59
-
-
77953229511
-
Dasatinib inhibits site-specific tyrosine phosphorylation of androgen receptor by Ack1 and Src kinases
-
Liu, Y., Karaca, M., Zhang, Z., Gioeli, D., Earp, H. S., & Whang, Y. E. (2010). Dasatinib inhibits site-specific tyrosine phosphorylation of androgen receptor by Ack1 and Src kinases. Oncogene, 29, 3208-3216.
-
(2010)
Oncogene
, vol.29
, pp. 3208-3216
-
-
Liu, Y.1
Karaca, M.2
Zhang, Z.3
Gioeli, D.4
Earp, H.S.5
Whang, Y.E.6
-
60
-
-
34648849274
-
Inhibition of the SH3 domain-mediated binding of Src to the androgen receptor and its effect on tumor growth
-
DOI 10.1038/sj.onc.1210487, PII 1210487
-
Migliaccio, A., Varricchio, L., de Falco, A., et al. (2007). Inhibition of the SH3 domain-mediated binding of Src to the androgen receptor and its effect on tumor growth. Oncogene, 26, 6619-6629. (Pubitemid 47573684)
-
(2007)
Oncogene
, vol.26
, Issue.46
, pp. 6619-6629
-
-
Migliaccio, A.1
Varricchio, L.2
De Falco, A.3
Castoria, G.4
Arra, C.5
Yamaguchi, H.6
Ciociola, A.7
Lombardi, M.8
Di, S.R.9
Barbieri, A.10
Baldi, A.11
Barone, M.V.12
Appella, E.13
Auricchio, F.14
-
61
-
-
0031929182
-
The ankyrin-binding domain of CD44s is involved in regulating hyaluronic acid-mediated functions and prostate tumor cell transformation
-
DOI 10.1002/(SICI)1097-0169(1998)39:3<209::AID-CM4
-
Zhu, D., & Bourguignon, L. Y. (1998). The ankyrin-binding domain of CD44s is involved in regulating hyaluronic acid-mediated functions and prostate tumor cell transformation. Cell Motil Cytoskeleton, 39, 209-222. (Pubitemid 28136563)
-
(1998)
Cell Motility and the Cytoskeleton
, vol.39
, Issue.3
, pp. 209-222
-
-
Zhu, D.1
Bourguignon, L.Y.W.2
-
62
-
-
9644259240
-
Integrin signaling links protein kinase Cepsilon to the protein kinase B/Akt survival pathway in recurrent prostate cancer cells
-
DOI 10.1038/sj.onc.1207900
-
Wu, D., Thakore, C. U., Wescott, G. G., McCubrey, J. A., & Terrian, D. M. (2004). Integrin signaling links protein kinase Cepsilon to the protein kinase B/Akt survival pathway in recurrent prostate cancer cells. Oncogene, 23, 8659-8672. (Pubitemid 39576473)
-
(2004)
Oncogene
, vol.23
, Issue.53
, pp. 8659-8672
-
-
Wu, D.1
Thakore, C.U.2
Wescott, G.G.3
McCubrey, J.A.4
Terrian, D.M.5
-
63
-
-
33748286819
-
Integrin-regulated FAK-Src signaling in normal and cancer cells
-
DOI 10.1016/j.ceb.2006.08.011, PII S0955067406001220
-
Mitra, S. K., & Schlaepfer, D. D. (2006). Integrin-regulated FAK-Src signaling in normal and cancer cells. Curr Opin Cell Biol, 18, 516-523. (Pubitemid 44332916)
-
(2006)
Current Opinion in Cell Biology
, vol.18
, Issue.5
, pp. 516-523
-
-
Mitra, S.K.1
Schlaepfer, D.D.2
-
64
-
-
30044445260
-
MUC1 oncoprotein is targeted to mitochondria by heregulin-induced activation of c-Src and the molecular chaperone HSP90
-
DOI 10.1016/j.jpain.2006.01.060
-
Ren, J., Bharti, A., Raina, D., Chen, W., Ahmad, R., & Kufe, D. (2006). MUC1 oncoprotein is targeted to mitochondria by heregulin-induced activation of c-Src and the molecular chaperone HSP90. Oncogene, 25, 20-31. (Pubitemid 43050000)
-
(2006)
Oncogene
, vol.25
, Issue.1
, pp. 20-31
-
-
Ren, J.1
Bharti, A.2
Raina, D.3
Chen, W.4
Ahmad, R.5
Kufe, D.6
-
65
-
-
34547106599
-
EphrinA1 activates a Src/focal adhesion kinase-mediated motility response leading to rho-dependent actino/myosin contractility
-
DOI 10.1074/jbc.M701319200
-
Parri, M., Buricchi, F., Giannoni, E., et al. (2007). EphrinA1 activates a Src/focal adhesion kinase-mediated motility response leading to rho-dependent actino/myosin contractility. J Biol Chem, 282, 19619-19628. (Pubitemid 47100120)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.27
, pp. 19619-19628
-
-
Parri, M.1
Buricchi, F.2
Giannoni, E.3
Grimaldi, G.4
Mello, T.5
Raugei, G.6
Ramponi, G.7
Chiarugi, P.8
-
66
-
-
77954355093
-
Shedding of RANKL by tumor-associated MT1-MMP activates Src-dependent prostate cancer cell migration
-
Sabbota, A. L., Kim, H. R., Zhe, X., Fridman, R., Bonfil, R. D., & Cher, M. L. (2010). Shedding of RANKL by tumor-associated MT1-MMP activates Src-dependent prostate cancer cell migration. Cancer Res, 70, 5558-5566.
-
(2010)
Cancer Res
, vol.70
, pp. 5558-5566
-
-
Sabbota, A.L.1
Kim, H.R.2
Zhe, X.3
Fridman, R.4
Bonfil, R.D.5
Cher, M.L.6
-
67
-
-
84880270856
-
Ligandin-dependent activation of MET through IGF-1/IGF-1R signaling
-
Varkaris, A., Gaur, S., Parikh, N. U., et al. (2013). Ligandin-dependent activation of MET through IGF-1/IGF-1R signaling. Int J Cancer, 133, 1536-1546.
-
(2013)
Int J Cancer
, vol.133
, pp. 1536-1546
-
-
Varkaris, A.1
Gaur, S.2
Parikh, N.U.3
-
68
-
-
84870481545
-
Bradykinin enhances cell migration in human prostate cancer cells through B2 receptor/PKCdelta/c-Src dependent signaling pathway
-
Yu, H. S., Lin, T. H., & Tang, C. H. (2013). Bradykinin enhances cell migration in human prostate cancer cells through B2 receptor/PKCdelta/c-Src dependent signaling pathway. Prostate, 73, 89-100.
-
(2013)
Prostate
, vol.73
, pp. 89-100
-
-
Yu, H.S.1
Lin, T.H.2
Tang, C.H.3
-
69
-
-
22544453858
-
Intracellular reactive oxygen species activate Src tyrosine kinase during cell adhesion and anchorage-dependent cell growth
-
DOI 10.1128/MCB.25.15.6391-6403.2005
-
Giannoni, E., Buricchi, F., Raugei, G., Ramponi, G., & Chiarugi, P. (2005). Intracellular reactive oxygen species activate Src tyrosine kinase during cell adhesion and anchorage-dependent cell growth. Mol Cell Biol, 25, 6391-6403. (Pubitemid 41023216)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.15
, pp. 6391-6403
-
-
Giannoni, E.1
Buricchi, F.2
Raugei, G.3
Ramponi, G.4
Chiarugi, P.5
-
70
-
-
80051793928
-
Invadosome regulation by adhesion signaling
-
Destaing, O., Block, M. R., Planus, E., & Albiges-Rizo, C. (2011). Invadosome regulation by adhesion signaling. Curr Opin Cell Biol, 23, 597-606.
-
(2011)
Curr Opin Cell Biol
, vol.23
, pp. 597-606
-
-
Destaing, O.1
Block, M.R.2
Planus, E.3
Albiges-Rizo, C.4
-
71
-
-
79952003043
-
Src-mediated regulation of homotypic cell adhesion: Implications for cancer progression and opportunities for therapeutic intervention
-
Wadhawan, A., Smith, C., Nicholson, R. I., Barrett-Lee, P., & Hiscox, S. (2011). Src-mediated regulation of homotypic cell adhesion: implications for cancer progression and opportunities for therapeutic intervention. Cancer Treat Rev, 37, 234-241.
-
(2011)
Cancer Treat Rev
, vol.37
, pp. 234-241
-
-
Wadhawan, A.1
Smith, C.2
Nicholson, R.I.3
Barrett-Lee, P.4
Hiscox, S.5
-
72
-
-
0029731588
-
Focal adhesions, contractility, and signaling
-
Burridge, K., & Chrzanowska-Wodnicka, M. (1996). Focal adhesions, contractility, and signaling. Annu Rev Cell Dev Biol, 12, 463-518.
-
(1996)
Annu Rev Cell Dev Biol
, vol.12
, pp. 463-518
-
-
Burridge, K.1
Chrzanowska-Wodnicka, M.2
-
73
-
-
4444338326
-
Src-mediated phosphorylation of focal adhesion kinase couples actin and adhesion dynamics to survival signaling
-
DOI 10.1128/MCB.24.18.8113-8133.2004
-
Westhoff, M. A., Serrels, B., Fincham, V. J., Frame, M. C., & Carragher, N. O. (2004). SRC-mediated phosphorylation of focal adhesion kinase couples actin and adhesion dynamics to survival signaling. Mol Cell Biol, 24, 8113-8133. (Pubitemid 39167461)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.18
, pp. 8113-8133
-
-
Westhoff, M.A.1
Serrels, B.2
Fincham, V.J.3
Frame, M.C.4
Carragher, N.O.5
-
74
-
-
1642586962
-
FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly
-
DOI 10.1038/ncb1094
-
Webb, D. J., Donais, K., Whitmore, L. A., et al. (2004). FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly. Nat Cell Biol, 6, 154-161. (Pubitemid 38425715)
-
(2004)
Nature Cell Biology
, vol.6
, Issue.2
, pp. 154-161
-
-
Webb, D.J.1
Donais, K.2
Whitmore, L.A.3
Thomas, S.M.4
Turner, C.E.5
Parsons, J.T.6
Horwitz, A.F.7
-
75
-
-
77953878405
-
Adherens junctions: From molecules to morphogenesis
-
Harris, T. J., & Tepass, U. (2010). Adherens junctions: from molecules to morphogenesis. Nat Rev Mol Cell Biol, 11, 502-514.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 502-514
-
-
Harris, T.J.1
Tepass, U.2
-
76
-
-
0027507028
-
Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene
-
DOI 10.1083/jcb.120.3.757
-
Behrens, J., Vakaet, L., Friis, R., et al. (1993). Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene. J Cell Biol, 120, 757-766. (Pubitemid 23035144)
-
(1993)
Journal of Cell Biology
, vol.120
, Issue.3
, pp. 757-766
-
-
Behrens, J.1
Vakaet, L.2
Friis, R.3
Winterhager, E.4
Van Roy, F.5
Mareel, M.M.6
Birchmeier, W.7
-
77
-
-
0027459346
-
P60(v-src) causes tyrosine phosphorylation and inactivation of the N-cadherin-catenin cell adhesion system
-
Hamaguchi, M., Matsuyoshi, N., Ohnishi, Y., Gotoh, B., Takeichi, M., & Nagai, Y. (1993). p60v-src causes tyrosine phosphorylation and inactivation of the N-cadherin-catenin cell adhesion system. EMBO J, 12, 307-314. (Pubitemid 23042409)
-
(1993)
EMBO Journal
, vol.12
, Issue.1
, pp. 307-314
-
-
Hamaguchi, M.1
Matsuyoshi, N.2
Ohnishi, Y.3
Gotoh, B.4
Takeichi, M.5
Nagai, Y.6
-
78
-
-
0035958886
-
Identification of Src phosphorylation sites in the catenin p120ctn
-
Mariner, D. J., Anastasiadis, P., Keilhack, H., Bohmer, F. D., Wang, J., & Reynolds, A. B. (2001). Identification of Src phosphorylation sites in the catenin p120ctn. J Biol Chem, 276, 28006-28013.
-
(2001)
J Biol Chem
, vol.276
, pp. 28006-28013
-
-
Mariner, D.J.1
Anastasiadis, P.2
Keilhack, H.3
Bohmer, F.D.4
Wang, J.5
Reynolds, A.B.6
-
79
-
-
61649122855
-
SRC-induced disassembly of adherens junctions requires localized phosphorylation and degradation of the rac activator tiam1
-
Woodcock, S. A., Rooney, C., Liontos, M., et al. (2009). SRC-induced disassembly of adherens junctions requires localized phosphorylation and degradation of the rac activator tiam1. Mol Cell, 33, 639-653.
-
(2009)
Mol Cell
, vol.33
, pp. 639-653
-
-
Woodcock, S.A.1
Rooney, C.2
Liontos, M.3
-
80
-
-
78649741585
-
Oncogenic Src requires a wild-type counterpart to regulate invadopodia maturation
-
Kelley, L. C., Ammer, A. G., Hayes, K. E., et al. (2010). Oncogenic Src requires a wild-type counterpart to regulate invadopodia maturation. J Cell Sci, 123, 3923-3932.
-
(2010)
J Cell Sci
, vol.123
, pp. 3923-3932
-
-
Kelley, L.C.1
Ammer, A.G.2
Hayes, K.E.3
-
81
-
-
84867398875
-
Spatiotemporal regulation of Src and its substrates at invadosomes
-
Boateng, L. R., & Huttenlocher, A. (2012). Spatiotemporal regulation of Src and its substrates at invadosomes. Eur J Cell Biol, 91, 878-888.
-
(2012)
Eur J Cell Biol
, vol.91
, pp. 878-888
-
-
Boateng, L.R.1
Huttenlocher, A.2
-
82
-
-
18444371712
-
Interaction of HSP90 to N-WASP leads to activation and protection from proteasome-dependent degradation
-
DOI 10.1038/sj.emboj.7600586
-
Park, S. J., Suetsugu, S., & Takenawa, T. (2005). Interaction of HSP90 to N-WASP leads to activation and protection from proteasome-dependent degradation. EMBO J, 24, 1557-1570. (Pubitemid 40646446)
-
(2005)
EMBO Journal
, vol.24
, Issue.8
, pp. 1557-1570
-
-
Park, S.J.1
Suetsugu, S.2
Takenawa, T.3
-
83
-
-
13844264301
-
The adaptor protein Tks5/Fish is required for podosome formation and function, and for the protease-driven invasion of cancer cells
-
DOI 10.1016/j.ccr.2005.01.006
-
Seals, D. F., Azucena, E. F., Jr., Pass, I., et al. (2005). The adaptor protein Tks5/Fish is required for podosome formation and function, and for the protease-driven invasion of cancer cells. Cancer Cell, 7, 155-165. (Pubitemid 40248341)
-
(2005)
Cancer Cell
, vol.7
, Issue.2
, pp. 155-165
-
-
Seals, D.F.1
Azucena Jr., E.F.2
Pass, I.3
Tesfay, L.4
Gordon, R.5
Woodrow, M.6
Resau, J.H.7
Courtneidge, S.A.8
-
84
-
-
65249116444
-
The novel adaptor protein Tks4 (SH3PXD2B) is required for functional podosome formation
-
Buschman, M. D., Bromann, P. A., Cejudo-Martin, P., Wen, F., Pass, I., & Courtneidge, S. A. (2009). The novel adaptor protein Tks4 (SH3PXD2B) is required for functional podosome formation. Mol Biol Cell, 20, 1302-1311.
-
(2009)
Mol Biol Cell
, vol.20
, pp. 1302-1311
-
-
Buschman, M.D.1
Bromann, P.A.2
Cejudo-Martin, P.3
Wen, F.4
Pass, I.5
Courtneidge, S.A.6
-
85
-
-
0038386613
-
Src family kinases in tumor progression and metastasis
-
DOI 10.1023/A:1023772912750
-
Summy, J. M., & Gallick, G. E. (2003). Src family kinases in tumor progression and metastasis. Cancer Metastasis Rev, 22, 337-358. (Pubitemid 36791891)
-
(2003)
Cancer and Metastasis Reviews
, vol.22
, Issue.4
, pp. 337-358
-
-
Summy, J.M.1
Gallick, G.E.2
-
86
-
-
27144547509
-
Action of the Src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells
-
DOI 10.1158/0008-5472.CAN-05-1731
-
Nam, S., Kim, D., Cheng, J. Q., et al. (2005). Action of the Src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells. Cancer Res, 65, 9185-9189. (Pubitemid 41507982)
-
(2005)
Cancer Research
, vol.65
, Issue.20
, pp. 9185-9189
-
-
Nam, S.1
Kim, D.2
Cheng, J.Q.3
Zhang, S.4
Lee, J.-H.5
Buettner, R.6
Mirosevich, J.7
Lee, F.Y.8
Jove, R.9
-
87
-
-
77952203697
-
SKI-606 (Bosutinib) blocks prostate cancer invasion, growth, and metastasis in vitro and in vivo through regulation of genes involved in cancer growth and skeletal metastasis
-
Rabbani, S. A., Valentino, M. L., Arakelian, A., Ali, S., & Boschelli, F. (2010). SKI-606 (Bosutinib) blocks prostate cancer invasion, growth, and metastasis in vitro and in vivo through regulation of genes involved in cancer growth and skeletal metastasis. Mol Cancer Ther, 9, 1147-1157.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 1147-1157
-
-
Rabbani, S.A.1
Valentino, M.L.2
Arakelian, A.3
Ali, S.4
Boschelli, F.5
-
88
-
-
33644686825
-
Pathogenesis and treatment of prostate cancer bone metastases: Targeting the lethal phenotype
-
DOI 10.1200/JCO.2005.03.0841
-
Loberg, R. D., Logothetis, C. J., Keller, E. T., & Pienta, K. J. (2005). Pathogenesis and treatment of prostate cancer bone metastases: targeting the lethal phenotype. J Clin Oncol, 23, 8232-8241. (Pubitemid 46211560)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.32
, pp. 8232-8241
-
-
Loberg, R.D.1
Logothetis, C.J.2
Keller, E.T.3
Pienta, K.J.4
-
89
-
-
33750738067
-
Basic mechanisms responsible for osteolytic and osteoblastic bone metastases
-
DOI 10.1158/1078-0432.CCR-06-1007
-
Guise, T. A., Mohammad, K. S., Clines, G., et al. (2006). Basic mechanisms responsible for osteolytic and osteoblastic bone metastases. Clin Cancer Res, 12, 6213s-6216s. (Pubitemid 44703792)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.20 PART 2
-
-
Guise, T.A.1
Mohammad, K.S.2
Clines, G.3
Stebbins, E.G.4
Wong, D.H.5
Higgins, L.S.6
Vessella, R.7
Corey, E.8
Padalecki, S.9
Suva, L.10
Chirgwin, J.M.11
Pearse12
Roodman13
Lipton14
Clohisy15
Weilbaecher16
Smith17
-
90
-
-
35848970582
-
Molecular biology of bone metastasis
-
DOI 10.1158/1535-7163.MCT-07-0234
-
Kingsley, L. A., Fournier, P. G., Chirgwin, J. M., & Guise, T. A. (2007). Molecular biology of bone metastasis. Mol Cancer Ther, 6, 2609-2617. (Pubitemid 350058141)
-
(2007)
Molecular Cancer Therapeutics
, vol.6
, Issue.10
, pp. 2609-2617
-
-
Kingsley, L.A.1
Fournier, P.G.J.2
Chirgwin, J.M.3
Guise, T.A.4
-
91
-
-
58149390625
-
Targeting Src signaling in metastatic bone disease
-
Araujo, J., & Logothetis, C. (2009). Targeting Src signaling in metastatic bone disease. Int J Cancer, 124, 1-6.
-
(2009)
Int J Cancer
, vol.124
, pp. 1-6
-
-
Araujo, J.1
Logothetis, C.2
-
92
-
-
0026023289
-
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
-
Soriano, P., Montgomery, C., Geske, R., & Bradley, A. (1991). Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice. Cell, 64, 693-702. (Pubitemid 121001157)
-
(1991)
Cell
, vol.64
, Issue.4
, pp. 693-702
-
-
Soriano, P.1
Montgomery, C.2
Geske, R.3
Bradley, A.4
-
93
-
-
28544451132
-
The role(s) of Src kinase and Cbl proteins in the regulation of osteoclast differentiation and function
-
Horne, W. C., Sanjay, A., Bruzzaniti, A., & Baron, R. (2005). The role(s) of Src kinase and Cbl proteins in the regulation of osteoclast differentiation and function. Immunol Rev, 208, 106-125. (Pubitemid 41746388)
-
(2005)
Immunological Reviews
, vol.208
, pp. 106-125
-
-
Horne, W.C.1
Sanjay, A.2
Bruzzaniti, A.3
Baron, R.4
-
94
-
-
0034676060
-
Decreased c-Src expression enhances osteoblast differentiation and bone formation
-
Marzia, M., Sims, N. A., Voit, S., et al. (2000). Decreased c-Src expression enhances osteoblast differentiation and bone formation. J Cell Biol, 151, 311-320.
-
(2000)
J Cell Biol
, vol.151
, pp. 311-320
-
-
Marzia, M.1
Sims, N.A.2
Voit, S.3
-
95
-
-
77953229623
-
Src family kinase/abl inhibitor dasatinib suppresses proliferation and enhances differentiation of osteoblasts
-
Lee, Y. C., Huang, C. F., Murshed, M., et al. (2010). Src family kinase/abl inhibitor dasatinib suppresses proliferation and enhances differentiation of osteoblasts. Oncogene, 29, 3196-3207.
-
(2010)
Oncogene
, vol.29
, pp. 3196-3207
-
-
Lee, Y.C.1
Huang, C.F.2
Murshed, M.3
-
96
-
-
84878299480
-
Increased serum insulin-like growth factor-1 levels are associated with prolonged response to dasatinib-based regimens in metastatic prostate cancer
-
Dayyani, F., Varkaris, A., Araujo, J. C., et al. (2013). Increased serum insulin-like growth factor-1 levels are associated with prolonged response to dasatinib-based regimens in metastatic prostate cancer. Prostate, 73, 979-985.
-
(2013)
Prostate
, vol.73
, pp. 979-985
-
-
Dayyani, F.1
Varkaris, A.2
Araujo, J.C.3
-
97
-
-
36348941863
-
Bone metastasis: Pathogenesis and therapeutic implications
-
DOI 10.1007/s10585-007-9112-8
-
Clezardin, P., & Teti, A. (2007). Bone metastasis: pathogenesis and therapeutic implications. Clin Exp Metastasis, 24, 599-608. (Pubitemid 50003596)
-
(2007)
Clinical and Experimental Metastasis
, vol.24
, Issue.8
, pp. 599-608
-
-
Clezardin, P.1
Teti, A.2
-
98
-
-
79958037582
-
Bone metastasis in prostate cancer: Emerging therapeutic strategies
-
Sturge, J., Caley, M. P., & Waxman, J. (2011). Bone metastasis in prostate cancer: emerging therapeutic strategies. Nat Rev Clin Oncol, 8, 357-368.
-
(2011)
Nat Rev Clin Oncol
, vol.8
, pp. 357-368
-
-
Sturge, J.1
Caley, M.P.2
Waxman, J.3
-
99
-
-
67650601930
-
Dasatinib inhibits the growth of prostate cancer in bone and provides additional protection from osteolysis
-
Koreckij, T., Nguyen, H., Brown, L. G., Yu, E. Y., Vessella, R. L., & Corey, E. (2009). Dasatinib inhibits the growth of prostate cancer in bone and provides additional protection from osteolysis. Br J Cancer, 101, 263-268.
-
(2009)
Br J Cancer
, vol.101
, pp. 263-268
-
-
Koreckij, T.1
Nguyen, H.2
Brown, L.G.3
Yu, E.Y.4
Vessella, R.L.5
Corey, E.6
-
100
-
-
0029068339
-
Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation
-
Mukhopadhyay, D., Tsiokas, L., Zhou, X. M., Foster, D., Brugge, J. S., & Sukhatme, V. P. (1995). Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation. Nature, 375, 577-581.
-
(1995)
Nature
, vol.375
, pp. 577-581
-
-
Mukhopadhyay, D.1
Tsiokas, L.2
Zhou, X.M.3
Foster, D.4
Brugge, J.S.5
Sukhatme, V.P.6
-
101
-
-
33748982652
-
Src activation of Stat3 is an independent requirement from NF-kappaB activation for constitutive IL-8 expression in human pancreatic adenocarcinoma cells
-
DOI 10.1007/s10456-006-9038-9
-
Trevino, J. G., Gray, M. J., Nawrocki, S. T., et al. (2006). Src activation of Stat3 is an independent requirement from NF-kappaB activation for constitutive IL-8 expression in human pancreatic adenocarcinoma cells. Angiogenesis, 9, 101-110. (Pubitemid 44440555)
-
(2006)
Angiogenesis
, vol.9
, Issue.2
, pp. 101-110
-
-
Trevino, J.G.1
Gray, M.J.2
Nawrocki, S.T.3
Summy, J.M.4
Lesslie, D.P.5
Evans, D.B.6
Sawyer, T.K.7
Shakespeare, W.C.8
Watowich, S.S.9
Chiao, P.J.10
McConkey, D.J.11
Gallick, G.E.12
-
102
-
-
57749172257
-
Src family kinases as mediators of endothelial permeability: Effects on inflammation and metastasis
-
Kim, M. P., Park, S. I., Kopetz, S., & Gallick, G. E. (2009). Src family kinases as mediators of endothelial permeability: effects on inflammation and metastasis. Cell Tissue Res, 335, 249-259.
-
(2009)
Cell Tissue Res
, vol.335
, pp. 249-259
-
-
Kim, M.P.1
Park, S.I.2
Kopetz, S.3
Gallick, G.E.4
-
103
-
-
38349124475
-
Regulation of endothelial permeability by Src kinase signaling: Vascular leakage versus transcellular transport of drugs and macromolecules
-
Hu, G., Place, A. T., & Minshall, R. D. (2008). Regulation of endothelial permeability by Src kinase signaling: vascular leakage versus transcellular transport of drugs and macromolecules. Chem Biol Interact, 171, 177-189.
-
(2008)
Chem Biol Interact
, vol.171
, pp. 177-189
-
-
Hu, G.1
Place, A.T.2
Minshall, R.D.3
-
104
-
-
38149085899
-
Tyrosine phosphorylation-dependence of caveolae-mediated endocytosis
-
Sverdlov, M., Shajahan, A. N., & Minshall, R. D. (2007). Tyrosine phosphorylation-dependence of caveolae-mediated endocytosis. J Cell Mol Med, 11, 1239-1250.
-
(2007)
J Cell Mol Med
, vol.11
, pp. 1239-1250
-
-
Sverdlov, M.1
Shajahan, A.N.2
Minshall, R.D.3
-
105
-
-
79956283619
-
Current status of SRC inhibitors in solid tumor malignancies
-
Puls, L. N., Eadens, M., & Messersmith, W. (2011). Current status of SRC inhibitors in solid tumor malignancies. Oncologist, 16, 566-578.
-
(2011)
Oncologist
, vol.16
, pp. 566-578
-
-
Puls, L.N.1
Eadens, M.2
Messersmith, W.3
-
106
-
-
70349673597
-
Phase I dose-escalation and pharmacokinetic study of dasatinib in patients with advanced solid tumors
-
Demetri, G. D., Lo, R. P., MacPherson, I. R., et al. (2009). Phase I dose-escalation and pharmacokinetic study of dasatinib in patients with advanced solid tumors. Clin Cancer Res, 15, 6232-6240.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 6232-6240
-
-
Demetri, G.D.1
Lo, R.P.2
MacPherson, I.R.3
-
107
-
-
73149115110
-
Phase II study of dasatinib in patients with metastatic castration-resistant prostate cancer
-
Yu, E. Y., Wilding, G., Posadas, E., et al. (2009). Phase II study of dasatinib in patients with metastatic castration-resistant prostate cancer. Clin Cancer Res, 15, 7421-7428.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7421-7428
-
-
Yu, E.Y.1
Wilding, G.2
Posadas, E.3
-
108
-
-
79955610443
-
Once-daily dasatinib: Expansion of phase II study evaluating safety and efficacy of dasatinib in patients with metastatic castration-resistant prostate cancer
-
Yu, E. Y., Massard, C., Gross, M. E., et al. (2011). Once-daily dasatinib: expansion of phase II study evaluating safety and efficacy of dasatinib in patients with metastatic castration-resistant prostate cancer. Urology, 77, 1166-1171.
-
(2011)
Urology
, vol.77
, pp. 1166-1171
-
-
Yu, E.Y.1
Massard, C.2
Gross, M.E.3
-
109
-
-
4744366279
-
Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer
-
DOI 10.1056/NEJMoa040720
-
Tannock, I. F., De, W. R., Berry, W. R., et al. (2004). Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer. N Engl J Med, 351, 1502-1512. (Pubitemid 39315317)
-
(2004)
New England Journal of Medicine
, vol.351
, Issue.15
, pp. 1502-1512
-
-
Tannock, I.F.1
De Wit, R.2
Berry, W.R.3
Horti, J.4
Pluzanska, A.5
Chi, K.N.6
Oudard, S.7
Theodore, C.8
James, N.D.9
Turesson, I.10
Rosenthal, M.A.11
Eisenberger, M.A.12
-
110
-
-
83855162892
-
Dasatinib combined with docetaxel for castration-resistant prostate cancer: Results from a phase 1-2 study
-
Araujo, J. C., Mathew, P., Armstrong, A. J., et al. (2012). Dasatinib combined with docetaxel for castration-resistant prostate cancer: results from a phase 1-2 study. Cancer, 118, 63-71.
-
(2012)
Cancer
, vol.118
, pp. 63-71
-
-
Araujo, J.C.1
Mathew, P.2
Armstrong, A.J.3
-
111
-
-
84876283322
-
Overall survival (OS) and safety of dasatinib/docetaxel versus docetaxel in patients with metastatic castration-resistant prostate cancer (mCRPC): Results from the randomized phase III READY trial
-
abstr LBA8
-
Araujo, J. C., Trudel, G. C., Saad, F., (2013). et al. Overall survival (OS) and safety of dasatinib/docetaxel versus docetaxel in patients with metastatic castration-resistant prostate cancer (mCRPC): results from the randomized phase III READY trial. J Clin Oncol (suppl 6; abstr LBA8)
-
(2013)
J Clin Oncol
, Issue.SUPPL. 6
-
-
Araujo, J.C.1
Trudel, G.C.2
Saad, F.3
-
112
-
-
77957602393
-
Phase I safety, pharmacokinetics, and inhibition of SRC activity study of saracatinib in patients with solid tumors
-
Baselga, J., Cervantes, A., Martinelli, E., et al. (2010). Phase I safety, pharmacokinetics, and inhibition of SRC activity study of saracatinib in patients with solid tumors. Clin Cancer Res, 16, 4876-4883.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 4876-4883
-
-
Baselga, J.1
Cervantes, A.2
Martinelli, E.3
-
113
-
-
61749096864
-
A phase II trial of the Src-kinase inhibitor AZD0530 in patients with advanced castration-resistant prostate cancer: A California Cancer Consortium study
-
Lara, P. N., Jr., Longmate, J., Evans, C. P., et al. (2009). A phase II trial of the Src-kinase inhibitor AZD0530 in patients with advanced castration-resistant prostate cancer: a California Cancer Consortium study. Anticancer Drugs, 20, 179-184.
-
(2009)
Anticancer Drugs
, vol.20
, pp. 179-184
-
-
Lara Jr., P.N.1
Longmate, J.2
Evans, C.P.3
-
114
-
-
80053185093
-
Thiazolyl N-benzyl- substituted acetamide derivatives: Synthesis, Src kinase inhibitory and anticancer activities
-
Fallah-Tafti, A., Foroumadi, A., Tiwari, R., et al. (2011). Thiazolyl N-benzyl- substituted acetamide derivatives: synthesis, Src kinase inhibitory and anticancer activities. Eur J Med Chem, 46, 4853-4858.
-
(2011)
Eur J Med Chem
, vol.46
, pp. 4853-4858
-
-
Fallah-Tafti, A.1
Foroumadi, A.2
Tiwari, R.3
-
115
-
-
84866096038
-
Peptidomimetic Src/pretubulin inhibitor KX-01 alone and in combination with paclitaxel suppresses growth, metastasis in human ER/PR/HER2-negative tumor xenografts
-
Anbalagan, M., Ali, A., Jones, R. K., et al. (2012). Peptidomimetic Src/pretubulin inhibitor KX-01 alone and in combination with paclitaxel suppresses growth, metastasis in human ER/PR/HER2-negative tumor xenografts. Mol Cancer Ther, 11, 1936-1947.
-
(2012)
Mol Cancer Ther
, vol.11
, pp. 1936-1947
-
-
Anbalagan, M.1
Ali, A.2
Jones, R.K.3
-
116
-
-
84880919122
-
A phase I trial of KX2-391, a novel non-ATP competitive substrate-pocket- directed SRC inhibitor, in patients with advanced malignancies
-
Naing, A., Cohen, R., Dy, G. K., et al. (2013). A phase I trial of KX2-391, a novel non-ATP competitive substrate-pocket- directed SRC inhibitor, in patients with advanced malignancies. Invest New Drugs, 31, 967-973.
-
(2013)
Invest New Drugs
, vol.31
, pp. 967-973
-
-
Naing, A.1
Cohen, R.2
Dy, G.K.3
|