메뉴 건너뛰기




Volumn 71, Issue 3, 2011, Pages 862-872

Invasive prostate carcinoma driven by c-Src and androgen receptor synergy

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; DASATINIB; GELATINASE B; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE P60; UVOMORULIN; VIMENTIN;

EID: 79551564924     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-10-1605     Document Type: Article
Times cited : (76)

References (45)
  • 4
    • 68149159298 scopus 로고    scopus 로고
    • ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells
    • Zong Y, Xin L, Goldstein AS, Lawson DA, Teitell MA, Witte ON. ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells. Proc Natl Acad Sci U S A 2009;106:12465-70.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 12465-12470
    • Zong, Y.1    Xin, L.2    Goldstein, A.S.3    Lawson, D.A.4    Teitell, M.A.5    Witte, O.N.6
  • 5
    • 10744222860 scopus 로고    scopus 로고
    • Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer
    • Wang S, Gao J, Lei Q, Rozengurt N, Pritchard C, Jiao J, et al. Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer. Cancer Cell 2003;4:209-21.
    • (2003) Cancer Cell , vol.4 , pp. 209-221
    • Wang, S.1    Gao, J.2    Lei, Q.3    Rozengurt, N.4    Pritchard, C.5    Jiao, J.6
  • 6
    • 0038002683 scopus 로고    scopus 로고
    • The EZH2 polycomb transcriptional repressor-a marker or mover of metastatic prostate cancer?
    • Sellers WR, Loda M. The EZH2 polycomb transcriptional repressor-a marker or mover of metastatic prostate cancer?Cancer Cell 2002;2:349-50.
    • (2002) Cancer Cell , vol.2 , pp. 349-350
    • Sellers, W.R.1    Loda, M.2
  • 8
    • 51449087794 scopus 로고    scopus 로고
    • Targeting the androgen receptor pathway in prostate cancer
    • Chen Y, Sawyers CL, Scher HI. Targeting the androgen receptor pathway in prostate cancer. Curr Opin Pharmacol 2008;8:440-8.
    • (2008) Curr Opin Pharmacol , vol.8 , pp. 440-448
    • Chen, Y.1    Sawyers, C.L.2    Scher, H.I.3
  • 11
    • 33749445413 scopus 로고    scopus 로고
    • Regulation of androgen receptor activity by tyrosine phosphorylation
    • Guo Z, Dai B, Jiang T, Xu K, Xie Y, Kim O, et al. Regulation of androgen receptor activity by tyrosine phosphorylation. Cancer Cell 2006;10:309-19.
    • (2006) Cancer Cell , vol.10 , pp. 309-319
    • Guo, Z.1    Dai, B.2    Jiang, T.3    Xu, K.4    Xie, Y.5    Kim, O.6
  • 12
    • 0033999589 scopus 로고    scopus 로고
    • No evidence of correlation between mutation at codon 531 of src and the risk of colon cancer in Chinese
    • Wang NM, Yeh KT, Tsai CH, Chen SJ, Chang JG. No evidence of correlation between mutation at codon 531 of src and the risk of colon cancer in Chinese. Cancer Lett 2000;150:201-4.
    • (2000) Cancer Lett , vol.150 , pp. 201-204
    • Wang, N.M.1    Yeh, K.T.2    Tsai, C.H.3    Chen, S.J.4    Chang, J.G.5
  • 13
    • 0033848230 scopus 로고    scopus 로고
    • Lack of activating c-SRC mutations at codon 531 in rectal cancer
    • Nilbert M, Fernebro E. Lack of activating c-SRC mutations at codon 531 in rectal cancer. Cancer Genet Cytogenet 2000;121:94-95.
    • (2000) Cancer Genet Cytogenet , vol.121 , pp. 94-95
    • Nilbert, M.1    Fernebro, E.2
  • 14
  • 15
    • 2942618768 scopus 로고    scopus 로고
    • A renaissance for SRC
    • Yeatman TJ. A renaissance for SRC. Nat Rev Cancer 2004;4:470-80.
    • (2004) Nat Rev Cancer , vol.4 , pp. 470-480
    • Yeatman, T.J.1
  • 16
    • 7944237784 scopus 로고    scopus 로고
    • The interplay between Src family kinases and receptor tyrosine kinases
    • Bromann PA, Korkaya H, Courtneidge SA. The interplay between Src family kinases and receptor tyrosine kinases. Oncogene 2004;23:7957-68.
    • (2004) Oncogene , vol.23 , pp. 7957-7968
    • Bromann, P.A.1    Korkaya, H.2    Courtneidge, S.A.3
  • 17
    • 33845298019 scopus 로고    scopus 로고
    • Receptor for activated C kinase 1 (RACK1) and Src regulate the tyrosine phosphorylation and function of the androgen receptor
    • Kraus S, Gioeli D, Vomastek T, Gordon V, Weber MJ. Receptor for activated C kinase 1 (RACK1) and Src regulate the tyrosine phosphorylation and function of the androgen receptor. Cancer Res 2006;66:11047-54.
    • (2006) Cancer Res , vol.66 , pp. 11047-11054
    • Kraus, S.1    Gioeli, D.2    Vomastek, T.3    Gordon, V.4    Weber, M.J.5
  • 18
    • 27544435790 scopus 로고    scopus 로고
    • The role of DOC-2/DAB2 in modulating androgen receptor-mediated cell growth via the nongenomic c-Src-mediated pathway in normal prostatic epithelium and cancer
    • DOI 10.1158/0008-5472.CAN-05-1481
    • Zhoul J, Hernandez G, Tu SW, Huang CL, Tseng CP, Hsieh JT. The role of DOC-2/DAB2 in modulating androgen receptor-mediated cell growth via the nongenomic c-Src-mediated pathway in normal prostatic epithelium and cancer. Cancer Res 2005;65:9906-13. (Pubitemid 41541471)
    • (2005) Cancer Research , vol.65 , Issue.21 , pp. 9906-9913
    • Zhoul, J.1    Hernandez, G.2    Tu, S.-W.3    Huang, C.-L.4    Tseng, C.-P.5    Hsieh, J.-T.6
  • 19
    • 0141483063 scopus 로고    scopus 로고
    • In vivo regeneration of murine prostate from dissociated cell populations of postnatal epithelia and urogenital sinus mesenchyme
    • Xin L, Ide H, Kim Y, Dubey P, Witte ON. In vivo regeneration of murine prostate from dissociated cell populations of postnatal epithelia and urogenital sinus mesenchyme. Proc Natl Acad Sci U S A 2003;100: Suppl 1:11896-903.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.SUPPL. 1 , pp. 11896-11903
    • Xin, L.1    Ide, H.2    Kim, Y.3    Dubey, P.4    Witte, O.N.5
  • 20
    • 36649036989 scopus 로고    scopus 로고
    • Enhanced paracrine FGF10 expression promotes formation of multifocal prostate adenocarcinoma and an increase in epithelial androgen receptor
    • Memarzadeh S, Xin L, Mulholland DJ, Mansukhani A, Wu H, Teitell MA, et al. Enhanced paracrine FGF10 expression promotes formation of multifocal prostate adenocarcinoma and an increase in epithelial androgen receptor. Cancer Cell 2007;12:572-85.
    • (2007) Cancer Cell , vol.12 , pp. 572-585
    • Memarzadeh, S.1    Xin, L.2    Mulholland, D.J.3    Mansukhani, A.4    Wu, H.5    Teitell, M.A.6
  • 23
    • 4444293504 scopus 로고    scopus 로고
    • Transactivator and structurally optimized inducible lentiviral vectors
    • Haack K, Cockrell AS, Ma H, Israeli D, Ho SN, McCown TJ, et al. Transactivator and structurally optimized inducible lentiviral vectors. Mol Ther 2004;10:585-96.
    • (2004) Mol Ther , vol.10 , pp. 585-596
    • Haack, K.1    Cockrell, A.S.2    Ma, H.3    Israeli, D.4    Ho, S.N.5    McCown, T.J.6
  • 24
    • 18844392836 scopus 로고    scopus 로고
    • Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues
    • Hochedlinger K, Yamada Y, Beard C, Jaenisch R. Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues. Cell 2005;121:465-77.
    • (2005) Cell , vol.121 , pp. 465-477
    • Hochedlinger, K.1    Yamada, Y.2    Beard, C.3    Jaenisch, R.4
  • 25
    • 67650996754 scopus 로고    scopus 로고
    • Biomarkers for epithelial-mesenchymal transitions
    • Zeisberg M, Neilson EG. Biomarkers for epithelial-mesenchymal transitions. J Clin Invest 2009;119:1429-37.
    • (2009) J Clin Invest , vol.119 , pp. 1429-1437
    • Zeisberg, M.1    Neilson, E.G.2
  • 26
    • 51449088226 scopus 로고    scopus 로고
    • Src and focal adhesion kinase as therapeutic targets in cancer
    • Brunton VG, Frame MC. Src and focal adhesion kinase as therapeutic targets in cancer. Curr Opin Pharmacol 2008;8:427-32.
    • (2008) Curr Opin Pharmacol , vol.8 , pp. 427-432
    • Brunton, V.G.1    Frame, M.C.2
  • 27
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelialmesenchymal transitions
    • Thiery JP, Sleeman JP. Complex networks orchestrate epithelialmesenchymal transitions. Nat Rev Mol Cell Biol 2006;7:131-42.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 28
    • 33749024777 scopus 로고    scopus 로고
    • Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis
    • Christiansen JJ, Rajasekaran AK. Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis. Cancer Res 2006;66:8319-26.
    • (2006) Cancer Res , vol.66 , pp. 8319-8326
    • Christiansen, J.J.1    Rajasekaran, A.K.2
  • 29
    • 44849134528 scopus 로고    scopus 로고
    • Targeting SRC family kinases inhibits growth and lymph node metastases of prostate cancer in an orthotopic nude mouse model
    • Park SI, Zhang J, Phillips KA, Araujo JC, Najjar AM, Volgin AY, et al. Targeting SRC family kinases inhibits growth and lymph node metastases of prostate cancer in an orthotopic nude mouse model. Cancer Res 2008;68:3323-33.
    • (2008) Cancer Res , vol.68 , pp. 3323-3333
    • Park, S.I.1    Zhang, J.2    Phillips, K.A.3    Araujo, J.C.4    Najjar, A.M.5    Volgin, A.Y.6
  • 30
    • 77950616066 scopus 로고    scopus 로고
    • SRC kinase inhibition: Targeting bone metastases and tumor growth in prostate and breast cancer
    • Saad F, Lipton A. SRC kinase inhibition: targeting bone metastases and tumor growth in prostate and breast cancer. Cancer Treat Rev 2010;36:177-84.
    • (2010) Cancer Treat Rev , vol.36 , pp. 177-184
    • Saad, F.1    Lipton, A.2
  • 31
    • 33748038440 scopus 로고    scopus 로고
    • Emergence of androgen independence at early stages of prostate cancer progressioninNkx3.1; Pten mice
    • Gao H, Ouyang X, Banach-Petrosky WA, Shen MM, Abate-Shen C. Emergence of androgen independence at early stages of prostate cancer progressioninNkx3.1; Pten mice.CancerRes 2006;66:7929-33.
    • (2006) CancerRes , vol.66 , pp. 7929-7933
    • Gao, H.1    Ouyang, X.2    Banach-Petrosky, W.A.3    Shen, M.M.4    Abate-Shen, C.5
  • 32
    • 33646342738 scopus 로고    scopus 로고
    • NKX3.1 stabilizes p53, inhibits AKT activation, and blocks prostate cancer initiation caused by PTEN loss
    • Lei Q, Jiao J, Xin L, Chang CJ, Wang S, Gao J, et al. NKX3.1 stabilizes p53, inhibits AKT activation, and blocks prostate cancer initiation caused by PTEN loss. Cancer Cell 2006;9:367-78.
    • (2006) Cancer Cell , vol.9 , pp. 367-378
    • Lei, Q.1    Jiao, J.2    Xin, L.3    Chang, C.J.4    Wang, S.5    Gao, J.6
  • 33
    • 0034125195 scopus 로고    scopus 로고
    • Glucocorticoids can promote androgen-independent growth of prostate cancer cells through a mutated androgen receptor
    • Zhao XY, Malloy PJ, Krishnan AV, Swami S, Navone NM, Peehl DM, et al. Glucocorticoids can promote androgen-independent growth of prostate cancer cells through a mutated androgen receptor. Nat Med 2000;6:703-6.
    • (2000) Nat Med , vol.6 , pp. 703-706
    • Zhao, X.Y.1    Malloy, P.J.2    Krishnan, A.V.3    Swami, S.4    Navone, N.M.5    Peehl, D.M.6
  • 35
    • 44849102368 scopus 로고    scopus 로고
    • Src kinase potentiates androgen receptor transactivation function and invasion of androgen-independent prostate cancer C4-2 cells
    • Asim M, Siddiqui IA, Hafeez BB, Baniahmad A, Mukhtar H. Src kinase potentiates androgen receptor transactivation function and invasion of androgen-independent prostate cancer C4-2 cells. Oncogene 2008;27:3596-604.
    • (2008) Oncogene , vol.27 , pp. 3596-3604
    • Asim, M.1    Siddiqui, I.A.2    Hafeez, B.B.3    Baniahmad, A.4    Mukhtar, H.5
  • 36
    • 0036205320 scopus 로고    scopus 로고
    • SRC catalytic but not scaffolding function is needed for integrin-regulated tyrosine phosphorylation, cell migration, and cell spreading
    • Cary LA, Klinghoffer RA, Sachsenmaier C, Cooper JA. SRC catalytic but not scaffolding function is needed for integrin-regulated tyrosine phosphorylation, cell migration, and cell spreading. Mol Cell Biol 2002;22:2427-40.
    • (2002) Mol Cell Biol , vol.22 , pp. 2427-2440
    • Cary, L.A.1    Klinghoffer, R.A.2    Sachsenmaier, C.3    Cooper, J.A.4
  • 37
    • 0030856131 scopus 로고    scopus 로고
    • Rescue of osteoclast function by transgenic expression of kinase-deficient Src in src-/- Mutant mice
    • Schwartzberg PL, Xing L, Hoffmann O, Lowell CA, Garrett L, Boyce BF, et al. Rescue of osteoclast function by transgenic expression of kinase-deficient Src in src-/- mutant mice. Genes Dev 1997;11:2835-44.
    • (1997) Genes Dev , vol.11 , pp. 2835-2844
    • Schwartzberg, P.L.1    Xing, L.2    Hoffmann, O.3    Lowell, C.A.4    Garrett, L.5    Boyce, B.F.6
  • 38
    • 24644471128 scopus 로고    scopus 로고
    • Src and FAK signalling controls adhesion fate and the epithelial-to-mesenchymal transition
    • Avizienyte E, Frame MC. Src and FAK signalling controls adhesion fate and the epithelial-to-mesenchymal transition. Curr Opin Cell Biol 2005;17:542-7.
    • (2005) Curr Opin Cell Biol , vol.17 , pp. 542-547
    • Avizienyte, E.1    Frame, M.C.2
  • 39
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • Thiery JP, Acloque H, Huang RY, Nieto MA. Epithelial-mesenchymal transitions in development and disease. Cell 2009;139:871-90.
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 40
    • 59249097068 scopus 로고    scopus 로고
    • Src as a therapeutic target in men with prostate cancer and bone metastases
    • Saad F. Src as a therapeutic target in men with prostate cancer and bone metastases. BJU Int 2009;103:434-40.
    • (2009) BJU Int , vol.103 , pp. 434-440
    • Saad, F.1
  • 41
    • 70349673597 scopus 로고    scopus 로고
    • Phase I dose-escalation and pharmacokinetic study of dasatinib in patients with advanced solid tumors
    • Demetri GD, Lo Russo P, MacPherson IR, Wang D, Morgan JA, Brunton VG, et al. Phase I dose-escalation and pharmacokinetic study of dasatinib in patients with advanced solid tumors. Clin Cancer Res 2009;15:6232-40.
    • (2009) Clin Cancer Res , vol.15 , pp. 6232-6240
    • Demetri, G.D.1    Lo Russo, P.2    MacPherson, I.R.3    Wang, D.4    Morgan, J.A.5    Brunton, V.G.6
  • 42
    • 77951474381 scopus 로고    scopus 로고
    • Src kinase inhibitors: An emerging therapeutic treatment option for prostate cancer
    • Edwards J. Src kinase inhibitors: an emerging therapeutic treatment option for prostate cancer. Expert Opin Investig Drugs 2010;19:605-14.
    • (2010) Expert Opin Investig Drugs , vol.19 , pp. 605-614
    • Edwards, J.1
  • 43
    • 77958508493 scopus 로고    scopus 로고
    • Docetaxel-based combination therapy for castration-resistant prostate cancer
    • Galsky MD, Vogelzang NJ. Docetaxel-based combination therapy for castration-resistant prostate cancer. Ann Oncol 2010;21:2135-44.
    • (2010) Ann Oncol , vol.21 , pp. 2135-2144
    • Galsky, M.D.1    Vogelzang, N.J.2
  • 44
    • 67649935641 scopus 로고    scopus 로고
    • Genomic approaches to outcome prediction in prostate cancer
    • Febbo PG. Genomic approaches to outcome prediction in prostate cancer. Cancer 2009;115:3046-57.
    • (2009) Cancer , vol.115 , pp. 3046-3057
    • Febbo, P.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.