Src-Induced Disassembly of Adherens Junctions Requires Localized Phosphorylation and Degradation of the Rac Activator Tiam1

Molecular Cell

Volumn 33, Issue 5, 2009, Pages 639-653

  Woodcock, Simon A ^a   Rooney, Claire ^a   Liontos, Michalis ^b   Connolly, Yvonne ^a   Zoumpourlis, Vassilis ^c   Whetton, Anthony D ^d   Gorgoulis, Vassilis G ^b   Malliri, Angeliki ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^c INSTITUTE OF BIOLOGY   (Greece)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

CELLCYCLE; SIGNALING

Indexed keywords

CALPAIN; PROTEIN TIAM1; RAC PROTEIN; UNCLASSIFIED DRUG; UVOMORULIN;

ARTICLE; CELL ADHESION; CELL JUNCTION; CELL MOTILITY; CELL STRAIN; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; PROTEIN DEGRADATION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION;

ADHERENS JUNCTIONS; ANIMALS; CALPAIN; CELL LINE; CELL MOVEMENT; CLONING, MOLECULAR; DOGS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GRB2 ADAPTOR PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; MAP KINASE KINASE KINASES; MICE; MICE, KNOCKOUT; MUTAGENESIS, SITE-DIRECTED; MUTATION; NEOPLASM INVASIVENESS; NEOPLASMS; ONCOGENE PROTEIN PP60(V-SRC); PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-MYC; PROTO-ONCOGENE PROTEINS C-YES; PROTO-ONCOGENE PROTEINS PP60(C-SRC); RECOMBINANT FUSION PROTEINS; SOS1 PROTEIN; SRC HOMOLOGY DOMAINS; SRC-FAMILY KINASES; TIME FACTORS; TRANSFECTION; TYROSINE;

EID: 61649122855     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2009.02.012     Document Type: Article

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