-
1
-
-
0033952191
-
Clinical states in prostate cancer: Towards a dynamic model of disease progression
-
Scher HI, Heller G: Clinical states in prostate cancer: Towards a dynamic model of disease progression. Urology 55:323-327, 2000
-
(2000)
Urology
, vol.55
, pp. 323-327
-
-
Scher, H.I.1
Heller, G.2
-
2
-
-
0024208596
-
The combination of cyproterone acetate and low dose diethylstilbestrol in the treatment of advanced prostatic carcinoma
-
Goldenberg SL, Bruchovsky N, Rennie PS, et al: The combination of cyproterone acetate and low dose diethylstilbestrol in the treatment of advanced prostatic carcinoma. J Urol 138: 1460-1465, 1988
-
(1988)
J Urol
, vol.138
, pp. 1460-1465
-
-
Goldenberg, S.L.1
Bruchovsky, N.2
Rennie, P.S.3
-
3
-
-
10844235652
-
Androgen-independent prostate cancer is a heterogeneous group of diseases: Lessons from a rapid autopsy program
-
Shah RB, Mehra R, Chinnaiyan AM, et al: Androgen-independent prostate cancer is a heterogeneous group of diseases: Lessons from a rapid autopsy program. Cancer Res 64:9209-9216, 2004
-
(2004)
Cancer Res
, vol.64
, pp. 9209-9216
-
-
Shah, R.B.1
Mehra, R.2
Chinnaiyan, A.M.3
-
4
-
-
0034895975
-
Collocation of androgen receptor gene mutations in prostate cancer
-
Buchanan G, Greenberg NM, Scher HI, et al: Collocation of androgen receptor gene mutations in prostate cancer. Clinical Cancer Res 7:1273-1281, 2001
-
(2001)
Clinical Cancer Res
, vol.7
, pp. 1273-1281
-
-
Buchanan, G.1
Greenberg, N.M.2
Scher, H.I.3
-
5
-
-
4744366279
-
Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer
-
Tannock IF, de Wit R, Berry WR, et al: Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer. N Engl J Med 351:1502-1512, 2004
-
(2004)
N Engl J Med
, vol.351
, pp. 1502-1512
-
-
Tannock, I.F.1
de Wit, R.2
Berry, W.R.3
-
6
-
-
4744337716
-
Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer
-
Petrylak DP, Tangen CM, Hussain MH, et al: Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer. N Engl J Med 351: 1513-1520, 2004
-
(2004)
N Engl J Med
, vol.351
, pp. 1513-1520
-
-
Petrylak, D.P.1
Tangen, C.M.2
Hussain, M.H.3
-
7
-
-
0033520806
-
Prostate cancer cell cycle regulators: Response to androgen withdrawal and development of androgen independence
-
Agus DB, Cordon-Cardo C, Fox W, et al: Prostate cancer cell cycle regulators: Response to androgen withdrawal and development of androgen independence. J Natl Cancer Inst 91: 1869-1876, 1999
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 1869-1876
-
-
Agus, D.B.1
Cordon-Cardo, C.2
Fox, W.3
-
8
-
-
0019841416
-
Adaptation versus selection as the mechanism responsible for the relapse of prostatic cancer to androgen ablation as studied in the Dunning R-3327 H adenocarcinoma
-
Isaacs JT, Coffey DS: Adaptation versus selection as the mechanism responsible for the relapse of prostatic cancer to androgen ablation as studied in the Dunning R-3327 H adenocarcinoma. Cancer Res 41:5070-5074, 1981
-
(1981)
Cancer Res
, vol.41
, pp. 5070-5074
-
-
Isaacs, J.T.1
Coffey, D.S.2
-
9
-
-
7244229599
-
Microarray analysis of prostate cancer progression to reduced androgen dependence: Studies in unique models contrasts early and late molecular events
-
Sirotnak FM, She Y, Khokhar NZ, et al: Microarray analysis of prostate cancer progression to reduced androgen dependence: Studies in unique models contrasts early and late molecular events. Mol Carcinog 41:150-163, 2004
-
(2004)
Mol Carcinog
, vol.41
, pp. 150-163
-
-
Sirotnak, F.M.1
She, Y.2
Khokhar, N.Z.3
-
10
-
-
0027477695
-
Prostate specific antigen decline after antiandrogen withdrawal: The flutamide withdrawal syndrome
-
Kelly WK, Scher HI: Prostate specific antigen decline after antiandrogen withdrawal: The flutamide withdrawal syndrome. J Urol 149:607-609, 1993
-
(1993)
J Urol
, vol.149
, pp. 607-609
-
-
Kelly, W.K.1
Scher, H.I.2
-
11
-
-
0030974734
-
The antiandrogen withdrawal syndrome
-
suppl 2
-
Wirth MP, Froschermaier SE: The antiandrogen withdrawal syndrome. Urol Res 25:S67-S71, 1997 (suppl 2)
-
(1997)
Urol Res
, vol.25
-
-
Wirth, M.P.1
Froschermaier, S.E.2
-
12
-
-
0030999075
-
Ketoconazole retains activity in advanced prostate cancer patients with progression despite flutamide withdrawal
-
Small EJ, Baron AD, Fippin L, et al: Ketoconazole retains activity in advanced prostate cancer patients with progression despite flutamide withdrawal. J Urol 157:1204-1207, 1997
-
(1997)
J Urol
, vol.157
, pp. 1204-1207
-
-
Small, E.J.1
Baron, A.D.2
Fippin, L.3
-
13
-
-
4944246790
-
Targeting the androgen receptor: Improving outcomes for castration-resistant prostate cancer
-
Scher HI, Buchanan G, Gerald W, et al: Targeting the androgen receptor: Improving outcomes for castration-resistant prostate cancer. Endocr Relat Cancer 11:459-476, 2004
-
(2004)
Endocr Relat Cancer
, vol.11
, pp. 459-476
-
-
Scher, H.I.1
Buchanan, G.2
Gerald, W.3
-
14
-
-
0037093092
-
Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: Results of a phase II study
-
Sawyers CL, Hochhaus A, Feldman E, et al: Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: Results of a phase II study. Blood 99:3530-3539, 2002
-
(2002)
Blood
, vol.99
, pp. 3530-3539
-
-
Sawyers, C.L.1
Hochhaus, A.2
Feldman, E.3
-
15
-
-
0035810148
-
Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor
-
Joensuu H, Roberts PJ, Sarlomo-Rikala M, et al: Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor. N Engl J Med 344:1052-1056, 2001
-
(2001)
N Engl J Med
, vol.344
, pp. 1052-1056
-
-
Joensuu, H.1
Roberts, P.J.2
Sarlomo-Rikala, M.3
-
16
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Janne PA, Lee JC, et al: EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy. Science 304:1497-1500, 2004
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
-
17
-
-
0034614108
-
Her-2-neu expression and progression toward independence in human prostate cancer
-
Signoretti S, Montiroini R, Manola J, et al: Her-2-neu expression and progression toward independence in human prostate cancer. J Natl Cancer Inst 92:1918-1925, 2000
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 1918-1925
-
-
Signoretti, S.1
Montiroini, R.2
Manola, J.3
-
18
-
-
0034808673
-
HER-2/neu (p185) protein expression in the natural and treated history of prostate cancer
-
Osman I, Scher H, Drobnjak M, et al: HER-2/neu (p185) protein expression in the natural and treated history of prostate cancer. Clin Cancer Res 7:2643-2647, 2001
-
(2001)
Clin Cancer Res
, vol.7
, pp. 2643-2647
-
-
Osman, I.1
Scher, H.2
Drobnjak, M.3
-
19
-
-
10744227995
-
Effects of blocking platelet-derived growth factor-receptor signaling in a mouse model of experimental prostate cancer bone metastases
-
Uehara H, Kim SJ, Karashima T, et al: Effects of blocking platelet-derived growth factor-receptor signaling in a mouse model of experimental prostate cancer bone metastases. J Natl Cancer Inst 95:458-470, 2003
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 458-470
-
-
Uehara, H.1
Kim, S.J.2
Karashima, T.3
-
20
-
-
4344717475
-
Platelet-derived growth factor receptor inhibitor imatinib mesylate and docetaxel: A modular phase I trial in androgen-independent prostate cancer
-
Mathew P, Thall PF, Jones D, et al: Platelet-derived growth factor receptor inhibitor imatinib mesylate and docetaxel: A modular phase I trial in androgen-independent prostate cancer. J Clin Oncol 22:3323-3329, 2004
-
(2004)
J Clin Oncol
, vol.22
, pp. 3323-3329
-
-
Mathew, P.1
Thall, P.F.2
Jones, D.3
-
21
-
-
4344665591
-
Prostate cancer and the MET hepatocyte growth factor receptor
-
Knudsen BS, Edlund M: Prostate cancer and the MET hepatocyte growth factor receptor. Adv Cancer Res 91:31-67, 2004
-
(2004)
Adv Cancer Res
, vol.91
, pp. 31-67
-
-
Knudsen, B.S.1
Edlund, M.2
-
22
-
-
15444349266
-
Frequent inactivation of PTEN/MMAC1 in primary prostate cancer
-
Cairns P, Okami K, Halachmi S, et al: Frequent inactivation of PTEN/MMAC1 in primary prostate cancer. Cancer Res 57:4997-5000, 1997
-
(1997)
Cancer Res
, vol.57
, pp. 4997-5000
-
-
Cairns, P.1
Okami, K.2
Halachmi, S.3
-
23
-
-
0032126505
-
Frequent inactivation of PTEN in prostate cancer cell lines and xenografts
-
Vlietstra RJ, van Alewijk DC, Hermans KG, et al: Frequent inactivation of PTEN in prostate cancer cell lines and xenografts. Cancer Res 58:2720-2723, 1998
-
(1998)
Cancer Res
, vol.58
, pp. 2720-2723
-
-
Vlietstra, R.J.1
van Alewijk, D.C.2
Hermans, K.G.3
-
24
-
-
0036632368
-
The phosphatidylinositol 3-Kinase AKT pathway in human cancer
-
Vivanco I, Sawyers CL: The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat Rev Cancer 2:489-501, 2002
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
25
-
-
0035930133
-
Androgen receptor signaling in androgen-refractory prostate cancer
-
Grossmann ME, Huang H, Tindall DJ: Androgen receptor signaling in androgen-refractory prostate cancer. J Natl Cancer Inst 93:1687-1697, 2001
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 1687-1697
-
-
Grossmann, M.E.1
Huang, H.2
Tindall, D.J.3
-
26
-
-
0035496220
-
The development of androgen independent prostate cancer
-
Feldman BJ, Feldman D: The development of androgen independent prostate cancer. Nat Rev Cancer 1:34-45, 2001
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 34-45
-
-
Feldman, B.J.1
Feldman, D.2
-
27
-
-
10844295905
-
Androgen-induced differentiation and tumorigenicity of human prostate epithelial cells
-
Berger R, Febbo PG, Majumder PK, et al: Androgen-induced differentiation and tumorigenicity of human prostate epithelial cells. Cancer Res 64:8867-8875, 2004
-
(2004)
Cancer Res
, vol.64
, pp. 8867-8875
-
-
Berger, R.1
Febbo, P.G.2
Majumder, P.K.3
-
28
-
-
1842612441
-
Molecular determinants of resistance to anti-androgen therapy
-
Chen CD, Welsbie DS, Tran C, et al: Molecular determinants of resistance to anti-androgen therapy. Nat Med 10:33-39, 2004
-
(2004)
Nat Med
, vol.10
, pp. 33-39
-
-
Chen, C.D.1
Welsbie, D.S.2
Tran, C.3
-
29
-
-
12844274300
-
Mutation of the androgen receptor causes oncogenic transformation of the prostate
-
Han G, Buchanan G, Ittmann M, et al: Mutation of the androgen receptor causes oncogenic transformation of the prostate. Proc Natl Acad Sci U S A 102:1151-1156, 2005
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 1151-1156
-
-
Han, G.1
Buchanan, G.2
Ittmann, M.3
-
30
-
-
21344441226
-
p300 regulates androgen receptor-independent expression of prostate-specific antigen in prostate cancer cells treated chronically with interleukin-6
-
Debes JD, Comuzzi B, Schmidt LJ, et al: p300 regulates androgen receptor-independent expression of prostate-specific antigen in prostate cancer cells treated chronically with interleukin-6. Cancer Res 65:5965-5973, 2005
-
(2005)
Cancer Res
, vol.65
, pp. 5965-5973
-
-
Debes, J.D.1
Comuzzi, B.2
Schmidt, L.J.3
-
31
-
-
3943079773
-
Androgen receptor signaling in prostate cancer
-
Henderson BE, Ponder BA, Ross RK eds, New York, NY, Oxford University Press
-
Tilley WD, Buchanan G, Coetzee GA: Androgen receptor signaling in prostate cancer, in Henderson BE, Ponder BA, Ross RK (eds): Hormones Genes and Cancer. New York, NY, Oxford University Press, 2003, pp 288-315
-
(2003)
Hormones Genes and Cancer
, pp. 288-315
-
-
Tilley, W.D.1
Buchanan, G.2
Coetzee, G.A.3
-
32
-
-
0025975826
-
Megestrol acetate plus low-dose estrogen in the management of advanced prostatic carcinoma
-
Geller J: Megestrol acetate plus low-dose estrogen in the management of advanced prostatic carcinoma. Urol Clin North Am 18:83-91, 1991
-
(1991)
Urol Clin North Am
, vol.18
, pp. 83-91
-
-
Geller, J.1
-
33
-
-
0021072579
-
New approach in the treatment of prostate cancer: Complete instead of partial withdrawal of androgens
-
Labrie F, Dupont A, Belanger A, et al: New approach in the treatment of prostate cancer: Complete instead of partial withdrawal of androgens. Prostate 4:579-594, 1983
-
(1983)
Prostate
, vol.4
, pp. 579-594
-
-
Labrie, F.1
Dupont, A.2
Belanger, A.3
-
34
-
-
0021167082
-
Ketoconazole therapy for advanced prostate cancer
-
Trachtenberg J, Pont A: Ketoconazole therapy for advanced prostate cancer. Lancet 2: 433-435, 1984
-
(1984)
Lancet
, vol.2
, pp. 433-435
-
-
Trachtenberg, J.1
Pont, A.2
-
35
-
-
0023154947
-
Aminoglutethimide in advanced prostatic carcinoma
-
Harnett PR, Raghavan D, Caterson I, et al: Aminoglutethimide in advanced prostatic carcinoma. Br J Urol 59:323-327, 1987
-
(1987)
Br J Urol
, vol.59
, pp. 323-327
-
-
Harnett, P.R.1
Raghavan, D.2
Caterson, I.3
-
37
-
-
27644452640
-
Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer
-
Titus MA, Schell MJ, Lih FB, et al: Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer. Clin Cancer Res 11:4653-4657, 2005
-
(2005)
Clin Cancer Res
, vol.11
, pp. 4653-4657
-
-
Titus, M.A.1
Schell, M.J.2
Lih, F.B.3
-
38
-
-
0027376310
-
Intracrinology: The basis for the rational design of endocrine therapy at all stages of prostate cancer
-
Labrie F, Dupont A, Simard J, et al: Intracrinology: The basis for the rational design of endocrine therapy at all stages of prostate cancer. Eur Urol 24:94-105, 1993
-
(1993)
Eur Urol
, vol.24
, pp. 94-105
-
-
Labrie, F.1
Dupont, A.2
Simard, J.3
-
39
-
-
1542574202
-
Gene expression analysis of human prostate carcinoma during hormonal therapy identifies androgen-responsive genes and mechanisms of therapy resistance
-
Holzbeierlein J, Lal P, LaTulippe E, et al: Gene expression analysis of human prostate carcinoma during hormonal therapy identifies androgen-responsive genes and mechanisms of therapy resistance. Am J Pathol 164:217-227, 2004
-
(2004)
Am J Pathol
, vol.164
, pp. 217-227
-
-
Holzbeierlein, J.1
Lal, P.2
LaTulippe, E.3
-
40
-
-
0032747375
-
Eligibility and response guidelines for phase II clinical trials in androgen-independent prostate cancer: Recommendations from the PSA Working Group
-
Bubley GJ, Carducci M, Dahut W, et al: Eligibility and response guidelines for phase II clinical trials in androgen-independent prostate cancer: Recommendations from the PSA Working Group. J Clin Oncol 17:3461-3467, 1999
-
(1999)
J Clin Oncol
, vol.17
, pp. 3461-3467
-
-
Bubley, G.J.1
Carducci, M.2
Dahut, W.3
-
41
-
-
0033557839
-
Survey of gene amplifications during prostate cancer progression by high-throughout flurorescence in situ hybridization on tissue microarrays
-
Bubendorf L, Kononen J, Koivisto P, et al: Survey of gene amplifications during prostate cancer progression by high-throughout flurorescence in situ hybridization on tissue microarrays. Cancer Res 59:803-806, 1999
-
(1999)
Cancer Res
, vol.59
, pp. 803-806
-
-
Bubendorf, L.1
Kononen, J.2
Koivisto, P.3
-
42
-
-
0030333504
-
Androgen receptor gene amplification: A novel molecular mechanism for endocrine therapy resistance in human prostate cancer
-
Koivisto P, Visakorpi T, Kallioniemi OP: Androgen receptor gene amplification: A novel molecular mechanism for endocrine therapy resistance in human prostate cancer. Scand J Clin Lab Invest Suppl 226:57-63, 1996
-
(1996)
Scand J Clin Lab Invest
, Issue.SUPPL. 226
, pp. 57-63
-
-
Koivisto, P.1
Visakorpi, T.2
Kallioniemi, O.P.3
-
43
-
-
0035328474
-
Amplification and overexpression of androgen receptor gene in hormone-refractory prostate cancer
-
Linja MJ, Savinainen KJ, Saramaki OR, et al: Amplification and overexpression of androgen receptor gene in hormone-refractory prostate cancer. Cancer Res 61:3550-3555, 2001
-
(2001)
Cancer Res
, vol.61
, pp. 3550-3555
-
-
Linja, M.J.1
Savinainen, K.J.2
Saramaki, O.R.3
-
44
-
-
0032535307
-
Androgen receptor expression in androgen-independent prostate cancer is associated with increased expression of androgen-regulated genes
-
Gregory CW, Hamil KG, Kim D, et al: Androgen receptor expression in androgen-independent prostate cancer is associated with increased expression of androgen-regulated genes. Cancer Res 58:5718-5724, 1998
-
(1998)
Cancer Res
, vol.58
, pp. 5718-5724
-
-
Gregory, C.W.1
Hamil, K.G.2
Kim, D.3
-
45
-
-
0034858061
-
Establishment of short-term primary human prostate xenografts for the study of prostate biology and cancer
-
Presnell SC, Werdin ES, Maygarden S, et al: Establishment of short-term primary human prostate xenografts for the study of prostate biology and cancer. Am J Pathol 159: 855-860, 2001
-
(2001)
Am J Pathol
, vol.159
, pp. 855-860
-
-
Presnell, S.C.1
Werdin, E.S.2
Maygarden, S.3
-
46
-
-
0035300409
-
Androgen receptor stabilization in recurrent prostate cancer is associated with hypersensitivity to low androgen
-
Gregory CW, Johnson RT, Mohler JL, et al. Androgen receptor stabilization in recurrent prostate cancer is associated with hypersensitivity to low androgen. Cancer Res 61:2892-2898, 2001
-
(2001)
Cancer Res
, vol.61
, pp. 2892-2898
-
-
Gregory, C.W.1
Johnson, R.T.2
Mohler, J.L.3
-
47
-
-
0035740251
-
Contribution of the androgen receptor to prostate cancer predisposition and progression
-
Buchanan G, Irvine RA, Cotzee GA, et al: Contribution of the androgen receptor to prostate cancer predisposition and progression. Cancer Metastatic Rev 20:207-223, 2001
-
(2001)
Cancer Metastatic Rev
, vol.20
, pp. 207-223
-
-
Buchanan, G.1
Irvine, R.A.2
Cotzee, G.A.3
-
48
-
-
0027536495
-
Image analysis of androgen receptor immunostaining in metastatic prostate cancer
-
Sadi MV, Barrack ER: Image analysis of androgen receptor immunostaining in metastatic prostate cancer. Cancer 71:2574-2580, 1993
-
(1993)
Cancer
, vol.71
, pp. 2574-2580
-
-
Sadi, M.V.1
Barrack, E.R.2
-
49
-
-
0029080807
-
Immunostaining for prostate cancer androgen receptor in parrafin identifies a subset of men with a poor prognosis
-
Pertschuk LP, Schaeffer H, Feldman JG, et al: Immunostaining for prostate cancer androgen receptor in parrafin identifies a subset of men with a poor prognosis. Lab Invest 73:302-305, 1995
-
(1995)
Lab Invest
, vol.73
, pp. 302-305
-
-
Pertschuk, L.P.1
Schaeffer, H.2
Feldman, J.G.3
-
50
-
-
0031946389
-
Expression, structure, and function of androgen receptor in advanced prostatic carcinoma
-
Culig Z, Hobisch A, Hittmair A, et al: Expression, structure, and function of androgen receptor in advanced prostatic carcinoma. Prostate 35:63-70, 1998
-
(1998)
Prostate
, vol.35
, pp. 63-70
-
-
Culig, Z.1
Hobisch, A.2
Hittmair, A.3
-
51
-
-
0036645414
-
Molecular biology of tne androgen receptor
-
Gelmann EP: Molecular biology of tne androgen receptor. J Clin Oncol 20:3001-3015, 2002
-
(2002)
J Clin Oncol
, vol.20
, pp. 3001-3015
-
-
Gelmann, E.P.1
-
52
-
-
17744378148
-
Mutations at the boundary of the hinge and ligand binding domain of the androgen receptor confer increased tansactivation function
-
Buchanan G, Yang M, Harris JM, et al: Mutations at the boundary of the hinge and ligand binding domain of the androgen receptor confer increased tansactivation function. Mol Endocrinol 15:46-56, 2000
-
(2000)
Mol Endocrinol
, vol.15
, pp. 46-56
-
-
Buchanan, G.1
Yang, M.2
Harris, J.M.3
-
53
-
-
2642544224
-
The androgen receptor gene mutations database (ARDB): 2004 update
-
Gottlieb B, Beitel LK, Wu JH, et al: The androgen receptor gene mutations database (ARDB): 2004 update. Hum Mutat 23:527-533, 2004
-
(2004)
Hum Mutat
, vol.23
, pp. 527-533
-
-
Gottlieb, B.1
Beitel, L.K.2
Wu, J.H.3
-
54
-
-
0030877225
-
Functional characterization of mutant androgen receptors from androgen-independent prostate cancer
-
Fenton MA, Shuster TD, Fertig AM, et al: Functional characterization of mutant androgen receptors from androgen-independent prostate cancer. Clin Cancer Res 8:1383-1388. 1997
-
(1997)
Clin Cancer Res
, vol.8
, pp. 1383-1388
-
-
Fenton, M.A.1
Shuster, T.D.2
Fertig, A.M.3
-
55
-
-
0033152164
-
Selection for androgen receptor mutations in prostate cancers treated with androgen antagonist
-
Taplin ME, Bubley GJ, Ko YJ, et al: Selection for androgen receptor mutations in prostate cancers treated with androgen antagonist. Cancer Res 59:2511-2515, 1999
-
(1999)
Cancer Res
, vol.59
, pp. 2511-2515
-
-
Taplin, M.E.1
Bubley, G.J.2
Ko, Y.J.3
-
56
-
-
0030811758
-
Bicalutamide for advanced prostate cancer: The natural vs. treated history of disease
-
Scher HI, Liebertz C, Kelly WK, et al: Bicalutamide for advanced prostate cancer: The natural vs. treated history of disease. J Clin Oncol 15:2928-2938, 1997
-
(1997)
J Clin Oncol
, vol.15
, pp. 2928-2938
-
-
Scher, H.I.1
Liebertz, C.2
Kelly, W.K.3
-
57
-
-
0031986409
-
High dose bicalutamide for androgen independent prostate cancer: Effect of prior hormonal therapy
-
Joyce R, Fenton MA, Rode P, et al: High dose bicalutamide for androgen independent prostate cancer: Effect of prior hormonal therapy. J Urol 159:149-153, 1998
-
(1998)
J Urol
, vol.159
, pp. 149-153
-
-
Joyce, R.1
Fenton, M.A.2
Rode, P.3
-
58
-
-
0037404165
-
Nilutamide as second line hormone therapy for prostate cancer after androgen ablation fails
-
Kassouf W, Tanguay S, Aprikian AG: Nilutamide as second line hormone therapy for prostate cancer after androgen ablation fails. J Urol 169:1742-1744, 2003
-
(2003)
J Urol
, vol.169
, pp. 1742-1744
-
-
Kassouf, W.1
Tanguay, S.2
Aprikian, A.G.3
-
59
-
-
17144432214
-
Androgen receptor corepressors: An overview
-
Wang L, Hsu CL, Chang C: Androgen receptor corepressors: An overview. Prostate 63:117-130, 2005
-
(2005)
Prostate
, vol.63
, pp. 117-130
-
-
Wang, L.1
Hsu, C.L.2
Chang, C.3
-
60
-
-
0032510686
-
From estrogen to androgen receptor: A new pathway for sex hormones in prostate
-
Yeh S. Miyamoto H, Shima H, et al: From estrogen to androgen receptor: A new pathway for sex hormones in prostate. Proc Natl Acad Sci U S A 95:5527-5532, 1998
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 5527-5532
-
-
Yeh, S.1
Miyamoto, H.2
Shima, H.3
-
61
-
-
0033398962
-
Differential induction of androgen receptor trans-activation by different androgen receptor coactivators in human prostate cancer DU145 cells
-
Yen S, Kang HY, Miyamoto H, et al. Differential induction of androgen receptor trans-activation by different androgen receptor coactivators in human prostate cancer DU145 cells. Endocrine 11:195-202, 1999
-
(1999)
Endocrine
, vol.11
, pp. 195-202
-
-
Yen, S.1
Kang, H.Y.2
Miyamoto, H.3
-
62
-
-
0035361340
-
A mechanism for androgen receptor-mediated prostate cancer recurrence after androgen deprivation therapy
-
Gregory CW, He B, Johnson RT, et al: A mechanism for androgen receptor-mediated prostate cancer recurrence after androgen deprivation therapy. Cancer Res 61:4315-4319, 2001
-
(2001)
Cancer Res
, vol.61
, pp. 4315-4319
-
-
Gregory, C.W.1
He, B.2
Johnson, R.T.3
-
63
-
-
2542638568
-
Differential modulation of androgen receptor transcriptional activity by the nuclear receptor corepressor (N-CoR)
-
Berrevoets CA, Umar A, Trapman J, et al. Differential modulation of androgen receptor transcriptional activity by the nuclear receptor corepressor (N-CoR). Biochem J 379:731-738, 2004
-
(2004)
Biochem J
, vol.379
, pp. 731-738
-
-
Berrevoets, C.A.1
Umar, A.2
Trapman, J.3
-
64
-
-
14844288915
-
The androgen receptor recruits nuclear receptor CoRepressor (N-CoR) in the presence of mifepristone via its N and C termini revealing a novel molecular mechanism for androgen receptor antagonists
-
Hodgson MC, Astapova I, Cheng S, et al: The androgen receptor recruits nuclear receptor CoRepressor (N-CoR) in the presence of mifepristone via its N and C termini revealing a novel molecular mechanism for androgen receptor antagonists. J Biol Chem 280:6511-6519, 2005
-
(2005)
J Biol Chem
, vol.280
, pp. 6511-6519
-
-
Hodgson, M.C.1
Astapova, I.2
Cheng, S.3
-
65
-
-
8344272750
-
Coregulator recruitment and histone modifications in transcriptional regulation by the androgen receptor
-
Kang Z, Janne OA, Palvimo JJ: Coregulator recruitment and histone modifications in transcriptional regulation by the androgen receptor. Mol Endocrinol 18:2633-2648, 2004
-
(2004)
Mol Endocrinol
, vol.18
, pp. 2633-2648
-
-
Kang, Z.1
Janne, O.A.2
Palvimo, J.J.3
-
66
-
-
0033022342
-
A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase
-
Craft N, Shostak Y, Carey M, et al: A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase. Nat Med 5:280-285, 1999
-
(1999)
Nat Med
, vol.5
, pp. 280-285
-
-
Craft, N.1
Shostak, Y.2
Carey, M.3
-
67
-
-
0037083383
-
HER-2 profiling and targeting in prostate carcinoma
-
Morris MJ, Reuter VE, Kelly WK, et al: HER-2 profiling and targeting in prostate carcinoma. Cancer 94:980-986, 2002
-
(2002)
Cancer
, vol.94
, pp. 980-986
-
-
Morris, M.J.1
Reuter, V.E.2
Kelly, W.K.3
-
68
-
-
0028113415
-
Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor
-
Culig Z, Hobisch A, Cronauer MV, et al: Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor. Cancer Res 54:5474-5478, 1994
-
(1994)
Cancer Res
, vol.54
, pp. 5474-5478
-
-
Culig, Z.1
Hobisch, A.2
Cronauer, M.V.3
-
69
-
-
0033545848
-
From HER2/ Neu signal cascade to androgen receptor and its coactivators: A novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells
-
Yeh S, Lin HK, Kang HY, et al: From HER2/ Neu signal cascade to androgen receptor and its coactivators: A novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells. Proc Natl Acad Sci U S A 96:5458-5463, 1999
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 5458-5463
-
-
Yeh, S.1
Lin, H.K.2
Kang, H.Y.3
-
70
-
-
0036510548
-
Activation of the androgen receptor N-terminal domain by interleukin-6 via MAPK and STAT3 signal transduction pathways
-
Ueda T, Bruchovsky N, Sadar MD: Activation of the androgen receptor N-terminal domain by interleukin-6 via MAPK and STAT3 signal transduction pathways. J Biol Chem 277:7076-7085, 2002
-
(2002)
J Biol Chem
, vol.277
, pp. 7076-7085
-
-
Ueda, T.1
Bruchovsky, N.2
Sadar, M.D.3
-
71
-
-
1342325380
-
Epidermal growth factor increases coactivation of the androgen receptor in recurrent prostate cancer
-
Gregory CW, Fei X, Ponguta LA, et al: Epidermal growth factor increases coactivation of the androgen receptor in recurrent prostate cancer. J Biol Chem 279:7119-7130, 2004
-
(2004)
J Biol Chem
, vol.279
, pp. 7119-7130
-
-
Gregory, C.W.1
Fei, X.2
Ponguta, L.A.3
-
72
-
-
0034671668
-
HER-2/ neu promotes androgen-independent survival and growth of prostate cancer cells through the AKT pathway
-
Wen Y, Hu MC, Makino K, et al: HER-2/ neu promotes androgen-independent survival and growth of prostate cancer cells through the AKT pathway. Cancer Res 60:6841-6845, 2000
-
(2000)
Cancer Res
, vol.60
, pp. 6841-6845
-
-
Wen, Y.1
Hu, M.C.2
Makino, K.3
-
73
-
-
7944234374
-
HER2/neu kinase-dependent modulation of androgen receptor function through effects on DNA binding and stability
-
Mellinghoff IK, Vivanco I, Kwon A, et al: HER2/neu kinase-dependent modulation of androgen receptor function through effects on DNA binding and stability. Cancer Cell 6:517-527, 2004
-
(2004)
Cancer Cell
, vol.6
, pp. 517-527
-
-
Mellinghoff, I.K.1
Vivanco, I.2
Kwon, A.3
-
74
-
-
0031594361
-
Bicalutamide (CasodexR) in the treatment of prostate cancer: History of clinical development
-
Kolvenbag GJ, Blackledge GR, Gotting-Smith K: Bicalutamide (CasodexR) in the treatment of prostate cancer: History of clinical development. Prostate 34:61-72, 1998
-
(1998)
Prostate
, vol.34
, pp. 61-72
-
-
Kolvenbag, G.J.1
Blackledge, G.R.2
Gotting-Smith, K.3
-
75
-
-
0030434949
-
Anti-androgenic effects of combination finasteride plus flutamide in patients with prostatic carcinoma
-
Fleshner N, Fair WR: Anti-androgenic effects of combination finasteride plus flutamide in patients with prostatic carcinoma. Br J Urol 78:907-910, 1996
-
(1996)
Br J Urol
, vol.78
, pp. 907-910
-
-
Fleshner, N.1
Fair, W.R.2
-
76
-
-
0022997273
-
Intermittent endocrine therapy for advanced prostate cancer
-
Klotz LH, Herr HW, Morse MJ, et al: Intermittent endocrine therapy for advanced prostate cancer. Cancer 58:2546-2550, 1986
-
(1986)
Cancer
, vol.58
, pp. 2546-2550
-
-
Klotz, L.H.1
Herr, H.W.2
Morse, M.J.3
-
77
-
-
0028892410
-
Intermittent androgen suppression in the treatment of prostate cancer: A preliminary report
-
Goldenberg SL, Bruchovsky N, Gleave ME, et al: Intermittent androgen suppression in the treatment of prostate cancer: A preliminary report. Urology 45:839-45, 1995
-
(1995)
Urology
, vol.45
, pp. 839-845
-
-
Goldenberg, S.L.1
Bruchovsky, N.2
Gleave, M.E.3
-
78
-
-
0027203411
-
The flutamide with drawal syndrome: Its impact on clinical trials in hormone-refractory prostatic cancer
-
Scher HI, Kelly WK: The flutamide with drawal syndrome: Its impact on clinical trials in hormone-refractory prostatic cancer. J Clin Oncol 11:1566-1572, 1993
-
(1993)
J Clin Oncol
, vol.11
, pp. 1566-1572
-
-
Scher, H.I.1
Kelly, W.K.2
-
79
-
-
0028898510
-
Withdrawal phenomenon with the antiandrogen casodex
-
Nieh PT: Withdrawal phenomenon with the antiandrogen casodex. J Urol 153:1070-1072, 1995
-
(1995)
J Urol
, vol.153
, pp. 1070-1072
-
-
Nieh, P.T.1
-
80
-
-
0030929675
-
Steroid hormone withdrawal syndromes: Pathophysiology and clinical significance
-
Kelly WK, Slovin S, Scher HI: Steroid hormone withdrawal syndromes: Pathophysiology and clinical significance. Urol Clin North Am 24:421-433, 1997
-
(1997)
Urol Clin North Am
, vol.24
, pp. 421-433
-
-
Kelly, W.K.1
Slovin, S.2
Scher, H.I.3
-
81
-
-
0029084601
-
The antiandrogen withdrawal syndrome: Experience in a large cohort of unselected patients with advanced prostate cancer
-
Small EJ, Srinivas S: The antiandrogen withdrawal syndrome: Experience in a large cohort of unselected patients with advanced prostate cancer. Cancer 76:1428-1434, 1995
-
(1995)
Cancer
, vol.76
, pp. 1428-1434
-
-
Small, E.J.1
Srinivas, S.2
-
82
-
-
0029027627
-
Complete remission of hormone refractory adenocarcinoma of the prostate in response to withdrawal of diethylstilbesterol
-
Bissada NK, Kaczmarek AT: Complete remission of hormone refractory adenocarcinoma of the prostate in response to withdrawal of diethylstilbesterol. J Urol 153:1944-1945, 1995
-
(1995)
J Urol
, vol.153
, pp. 1944-1945
-
-
Bissada, N.K.1
Kaczmarek, A.T.2
-
83
-
-
0031749852
-
Incidence and characteristics of antiandrogen withdrawal syndrome in prostate cancer after treatment with chlormadinone acetate
-
Akakura K, Akimoto S, Furuya Y, et al: Incidence and characteristics of antiandrogen withdrawal syndrome in prostate cancer after treatment with chlormadinone acetate. Eur Urol 33:567-571, 1998
-
(1998)
Eur Urol
, vol.33
, pp. 567-571
-
-
Akakura, K.1
Akimoto, S.2
Furuya, Y.3
-
84
-
-
0028864735
-
A controlled trial of bicalutamide versus flutamide, each in combination with luteinizing hormone-releasing hormone analogue therapy, in patients with advanced prostate cancer
-
Schellhammer PF, Sharifi R, Block NL, et al: A controlled trial of bicalutamide versus flutamide, each in combination with luteinizing hormone-releasing hormone analogue therapy, in patients with advanced prostate cancer. Urology 45:745-752, 1995
-
(1995)
Urology
, vol.45
, pp. 745-752
-
-
Schellhammer, P.F.1
Sharifi, R.2
Block, N.L.3
-
85
-
-
0028876979
-
Estrogens in the treatment of prostate cancer
-
Cox RL, Crawford ED: Estrogens in the treatment of prostate cancer. J Urol 154:1991-1998, 1995
-
(1995)
J Urol
, vol.154
, pp. 1991-1998
-
-
Cox, R.L.1
Crawford, E.D.2
-
86
-
-
0021347052
-
Clinical effect of aminoglutethimide, medical adrenalectomy, in treatment of 43 patients with advanced prostatic carcinoma
-
Drago JR, Santen RJ, Lipton A, et al: Clinical effect of aminoglutethimide, medical adrenalectomy, in treatment of 43 patients with advanced prostatic carcinoma. Cancer 53:1447-1450, 1984
-
(1984)
Cancer
, vol.53
, pp. 1447-1450
-
-
Drago, J.R.1
Santen, R.J.2
Lipton, A.3
-
87
-
-
0024389842
-
High-dose ketoconazole in advanced hormone-refractory prostate cancer: Endocrinologic and clinical effects
-
Trump DL, Havlin KH, Messing ED, et al: High-dose ketoconazole in advanced hormone-refractory prostate cancer: Endocrinologic and clinical effects. J Clin Oncol 7:1093-1098, 1989
-
(1989)
J Clin Oncol
, vol.7
, pp. 1093-1098
-
-
Trump, D.L.1
Havlin, K.H.2
Messing, E.D.3
-
88
-
-
3042784503
-
Hormonal impact of the 17alpha-hydroxylase/ C(17,20)-lyase inhibitor abiraterone acetate (CB7630) in patients with prostate cancer
-
O'Donnell A, Judson I, Dowsett M, et al: Hormonal impact of the 17alpha-hydroxylase/ C(17,20)-lyase inhibitor abiraterone acetate (CB7630) in patients with prostate cancer. Br J Cancer 90:2317-2325, 2004
-
(2004)
Br J Cancer
, vol.90
, pp. 2317-2325
-
-
O'Donnell, A.1
Judson, I.2
Dowsett, M.3
-
89
-
-
21244500193
-
Inhibition of p450 17 as a new strategy for the treatment of prostate cancer
-
Leroux F: Inhibition of p450 17 as a new strategy for the treatment of prostate cancer. Curr Med Chem 12:1623-1629, 2005
-
(2005)
Curr Med Chem
, vol.12
, pp. 1623-1629
-
-
Leroux, F.1
-
90
-
-
10044264506
-
Negative modulation of androgen receptor transcriptional activity by Daxx
-
Lin DY, Fang HI, Ma AH, et al: Negative modulation of androgen receptor transcriptional activity by Daxx. Mol Cell Biol 24:10529-10541, 2004
-
(2004)
Mol Cell Biol
, vol.24
, pp. 10529-10541
-
-
Lin, D.Y.1
Fang, H.I.2
Ma, A.H.3
-
91
-
-
0033930522
-
Inhibition of LncaP prostate cancer cells by means of androgen receptor antisense oligonucleotides
-
Eder IE, Culig Z, Ramoner R, et al: Inhibition of LncaP prostate cancer cells by means of androgen receptor antisense oligonucleotides. Cancer Gene Ther 7:997-1007, 2000
-
(2000)
Cancer Gene Ther
, vol.7
, pp. 997-1007
-
-
Eder, I.E.1
Culig, Z.2
Ramoner, R.3
-
92
-
-
0036170838
-
Disruption of androgen receptor function inhibits proliferation of androgen-refractory prostate cancer cells
-
Zegarra-Moro OL, Schmidt LJ, Huang H, et al: Disruption of androgen receptor function inhibits proliferation of androgen-refractory prostate cancer cells. Cancer Res 62:1008-1013, 2002
-
(2002)
Cancer Res
, vol.62
, pp. 1008-1013
-
-
Zegarra-Moro, O.L.1
Schmidt, L.J.2
Huang, H.3
-
93
-
-
4143129940
-
Androgen receptor down-regulation in prostate cancer with phosphorodiamidate morpholino antisense oligomers
-
Ko YJ, Devi GR, London CA, et al: Androgen receptor down-regulation in prostate cancer with phosphorodiamidate morpholino antisense oligomers. J Urol 172:1140-1144, 2004
-
(2004)
J Urol
, vol.172
, pp. 1140-1144
-
-
Ko, Y.J.1
Devi, G.R.2
London, C.A.3
-
94
-
-
3242763056
-
Antiandrogen oligonucleotides: Active principles in hair- and skin-derived culture cells
-
Balana ME, Alvarez Roger C, Dugour AV, et al: Antiandrogen oligonucleotides: Active principles in hair- and skin-derived culture cells. J Drugs Dermatol 3:287-294, 2004
-
(2004)
J Drugs Dermatol
, vol.3
, pp. 287-294
-
-
Balana, M.E.1
Alvarez Roger, C.2
Dugour, A.V.3
-
95
-
-
3042645268
-
Antisense approaches in prostate cancer
-
Chi KN, Cleave ME: Antisense approaches in prostate cancer. Expert Opin Biol Ther 4:927-936, 2004
-
(2004)
Expert Opin Biol Ther
, vol.4
, pp. 927-936
-
-
Chi, K.N.1
Cleave, M.E.2
-
96
-
-
0030863995
-
The amino-terminal domain of heat shock protein (hsp90) that binds geldanamycin is an ATP/ADP switch that regulates hsp90 conformation
-
Grenert J, Sullivan W, Fadden P, et al: The amino-terminal domain of heat shock protein (hsp90) that binds geldanamycin is an ATP/ADP switch that regulates hsp90 conformation. J Biol Chem 272:23843-23850, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 23843-23850
-
-
Grenert, J.1
Sullivan, W.2
Fadden, P.3
-
97
-
-
0031005361
-
Crystal structure of an Hsp90-geldanamycin complex: Targeting of a proetin chaperone by an antitumor agent
-
Stebbins CE, Russo AA, Schneider C, et al: Crystal structure of an Hsp90-geldanamycin complex: Targeting of a proetin chaperone by an antitumor agent. Cell 89:239-250, 1997
-
(1997)
Cell
, vol.89
, pp. 239-250
-
-
Stebbins, C.E.1
Russo, A.A.2
Schneider, C.3
-
98
-
-
0142125911
-
Hsp90 as a therapeutic target in prostate cancer
-
Solit DB, Scher HI, Rosen N: Hsp90 as a therapeutic target in prostate cancer. Semin Oncol 30:709-716, 2003
-
(2003)
Semin Oncol
, vol.30
, pp. 709-716
-
-
Solit, D.B.1
Scher, H.I.2
Rosen, N.3
-
99
-
-
84871472247
-
Phase I trial of 17AAG (17-allylamino) 17-demethoxygeldanamycin (17AAG) in patients (Pts) with advanced cancer., Molecular Targets and Cancer Therapeutics: Discovery, biology, and clinical applications
-
abstr 292, 3712s
-
Scher HI, Solit DB, Munster PN, et al: Phase I trial of 17AAG (17-allylamino) 17-demethoxygeldanamycin (17AAG) in patients (Pts) with advanced cancer., Molecular Targets and Cancer Therapeutics: Discovery, biology, and clinical applications. Clin Cancer Res 7:3712s, 2001 (abstr 292)
-
(2001)
Clin Cancer Res
, vol.7
-
-
Scher, H.I.1
Solit, D.B.2
Munster, P.N.3
-
100
-
-
20044384168
-
Phase I trial of 17-allylamino-17- demethoxygeldanamycin in patients with advanced cancer
-
Goetz MP, Toft D, Reid J, et al: Phase I trial of 17-allylamino-17- demethoxygeldanamycin in patients with advanced cancer. J Clin Oncol 23:1078-1087, 2005
-
(2005)
J Clin Oncol
, vol.23
, pp. 1078-1087
-
-
Goetz, M.P.1
Toft, D.2
Reid, J.3
-
101
-
-
23044441106
-
Phase I pharmacokinetic and pharmacodynamic study of 17-allylamino, 17-demethoxygeldanamycin in patients with advanced malignancies
-
Banerji U, O'Donnell A, Scurr M, et al: Phase I pharmacokinetic and pharmacodynamic study of 17-allylamino, 17-demethoxygeldanamycin in patients with advanced malignancies. J Clin Oncol 23:4152-4161, 2005
-
(2005)
J Clin Oncol
, vol.23
, pp. 4152-4161
-
-
Banerji, U.1
O'Donnell, A.2
Scurr, M.3
-
102
-
-
20144375312
-
Phase I and pharmacologic study of 17-(allylamino)-17-demethoxygeldanamycin in adult patients with solid tumors
-
Grem JL, Morrison G, Guo XD, et al: Phase I and pharmacologic study of 17-(allylamino)-17-demethoxygeldanamycin in adult patients with solid tumors. J Clin Oncol 23:1885-1893, 2005
-
(2005)
J Clin Oncol
, vol.23
, pp. 1885-1893
-
-
Grem, J.L.1
Morrison, G.2
Guo, X.D.3
-
103
-
-
17844376217
-
Structural basis for antagonism and resistance of bicalutamide in prostate cancer
-
Bohl CE, Gao W, Miller DD, et al: Structural basis for antagonism and resistance of bicalutamide in prostate cancer. Proc Natl Acad Sci U S A 102:6201-6206, 2005
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 6201-6206
-
-
Bohl, C.E.1
Gao, W.2
Miller, D.D.3
-
104
-
-
0034665124
-
Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo
-
Butler LM, Agus DB, Scher HI, et al: Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo. Cancer Res 60:5165-5170, 2000
-
(2000)
Cancer Res
, vol.60
, pp. 5165-5170
-
-
Butler, L.M.1
Agus, D.B.2
Scher, H.I.3
-
105
-
-
0035950410
-
Repression of androgen-regulated gene expression by dominant negative androgen receptors
-
Bramlett KS, Dits NF, Sui X, et al: Repression of androgen-regulated gene expression by dominant negative androgen receptors. Mol Cell Endocrinol 183:19-28, 2001
-
(2001)
Mol Cell Endocrinol
, vol.183
, pp. 19-28
-
-
Bramlett, K.S.1
Dits, N.F.2
Sui, X.3
-
106
-
-
0035755974
-
Histone deacetylases and cancer: Causes and therapies
-
Marks P, Rifkind RA, Richon VM, et al: Histone deacetylases and cancer: Causes and therapies. Nat Rev Cancer 1:194-202, 2001
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 194-202
-
-
Marks, P.1
Rifkind, R.A.2
Richon, V.M.3
-
107
-
-
33644696512
-
Chemical ablation of androgen receptor in prostate cancer cells by the histone deacetylase inhibitor LAQ824
-
Chen L, Meng S, Wang H, et al: Chemical ablation of androgen receptor in prostate cancer cells by the histone deacetylase inhibitor LAQ824. Mol Cancer Ther 4:1311-1319, 2005
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 1311-1319
-
-
Chen, L.1
Meng, S.2
Wang, H.3
-
108
-
-
0033672431
-
Modifying histones to tame cancer: Clinical development of sodium phenylbutyrate and other histone deacetylase inhibitors
-
Gore SD, Carducci MA: Modifying histones to tame cancer: Clinical development of sodium phenylbutyrate and other histone deacetylase inhibitors. Expert Opin Investig Drugs 9:2923-2934, 2000
-
(2000)
Expert Opin Investig Drugs
, vol.9
, pp. 2923-2934
-
-
Gore, S.D.1
Carducci, M.A.2
-
109
-
-
0034796871
-
A phase I clinical and pharmacological evaluation of sodium phenylbutyrate on an 120-h infusion schedule
-
Carducci MA, Gilbert J, Bowling MK, et al: A phase I clinical and pharmacological evaluation of sodium phenylbutyrate on an 120-h infusion schedule. Clin Cancer Res 7:3047-3055, 2001
-
(2001)
Clin Cancer Res
, vol.7
, pp. 3047-3055
-
-
Carducci, M.A.1
Gilbert, J.2
Bowling, M.K.3
-
110
-
-
12444321545
-
Phase I clinical trial of histone deactylase inhibitor: Suberylanilide hydroxamic acid (SAHA) administered intravenously
-
Kelly WK, Richon VM, O'Connor O, et al: Phase I clinical trial of histone deactylase inhibitor: suberylanilide hydroxamic acid (SAHA) administered intravenously. Clin Cancer Res 9:3578-3588, 2003
-
(2003)
Clin Cancer Res
, vol.9
, pp. 3578-3588
-
-
Kelly, W.K.1
Richon, V.M.2
O'Connor, O.3
-
111
-
-
0000393528
-
Epidermal growth factor receptor (EGFr) monoclonal antibody (MoAb) C225 and doxorubicin (DOC) in androgen-independent (AI) prostate cancer (PC): Results of a phase Ib/IIa study
-
16:, abstr 1108
-
Slovin SF, Kelly WK, Cohen R, et al: Epidermal growth factor receptor (EGFr) monoclonal antibody (MoAb) C225 and doxorubicin (DOC) in androgen-independent (AI) prostate cancer (PC): Results of a phase Ib/IIa study. Proc Amer Soc Clin One 16:311, 1997 (abstr 1108)
-
(1997)
Proc Amer Soc Clin
, vol.One
, pp. 311
-
-
Slovin, S.F.1
Kelly, W.K.2
Cohen, R.3
-
112
-
-
19044380618
-
Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth
-
Agus D, Akita R, Fox W, et al: Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth. Cancer Cell 2:127-137, 2002
-
(2002)
Cancer Cell
, vol.2
, pp. 127-137
-
-
Agus, D.1
Akita, R.2
Fox, W.3
-
113
-
-
11244263034
-
Inhibition of the epidermal growth factor receptor (EGFR) in hormone refractory prostate cancer (HRPC): Initial results of a phase II trial of gefitinib
-
abstr 1671
-
Rosenthal M, Toner GC, Gurney H, et al: Inhibition of the epidermal growth factor receptor (EGFR) in hormone refractory prostate cancer (HRPC): Initial results of a phase II trial of gefitinib. Proc Am Soc Clin Oncol 22:416, 2003 (abstr 1671)
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
, pp. 416
-
-
Rosenthal, M.1
Toner, G.C.2
Gurney, H.3
-
114
-
-
0346499118
-
Novel therapeutic molecular targets for prostate cancer: The mTOR signaling pathway and epidermal growth factor receptor
-
Tolcher AW: Novel therapeutic molecular targets for prostate cancer: The mTOR signaling pathway and epidermal growth factor receptor. J Urol 171:S41-44, 2004
-
(2004)
J Urol
, vol.171
-
-
Tolcher, A.W.1
-
115
-
-
0037616593
-
Loss of PTEN/MMAC1/TEP in EGF receptor-expressing tumor cells counteracts the antitumor action of EGFR tyrosine kinase inhibitors
-
Bianco R, Shin I, Ritter CA, et al: Loss of PTEN/MMAC1/TEP in EGF receptor-expressing tumor cells counteracts the antitumor action of EGFR tyrosine kinase inhibitors. Oncogene 22:2812-2822, 2003
-
(2003)
Oncogene
, vol.22
, pp. 2812-2822
-
-
Bianco, R.1
Shin, I.2
Ritter, C.A.3
-
116
-
-
0141960451
-
Resistance to gefitinib in PTEN-null HER-overexpressing tumor cells can be overcome through restoration of PTEN function or pharmacologic modulation of constitutive phosphatidylinositol 3′-kinase/Akt pathway signaling
-
She QB, Solit D, Basso A, et al: Resistance to gefitinib in PTEN-null HER-overexpressing tumor cells can be overcome through restoration of PTEN function or pharmacologic modulation of constitutive phosphatidylinositol 3′-kinase/Akt pathway signaling. Clin Cancer Res 9:4340-4346, 2003
-
(2003)
Clin Cancer Res
, vol.9
, pp. 4340-4346
-
-
She, Q.B.1
Solit, D.2
Basso, A.3
-
117
-
-
16344392867
-
Pulsatile administration of the epidermal growth factor receptor inhibitor gefitinib is significantly more effective than continuous dosing for sensitizing tumors to paclitaxel
-
Solit DB, She Y, Lobo J, et al: Pulsatile administration of the epidermal growth factor receptor inhibitor gefitinib is significantly more effective than continuous dosing for sensitizing tumors to paclitaxel. Clin Cancer Res 11:1983-1989, 2005
-
(2005)
Clin Cancer Res
, vol.11
, pp. 1983-1989
-
-
Solit, D.B.1
She, Y.2
Lobo, J.3
-
118
-
-
18244378478
-
Phase 1 pharmacokinetic and pharmacodynamic trial of docetaxel and 17AAG (17-allylamino-17- demethoxygeladanamycin)
-
suppl; abstr 3032
-
Solit DB, Egorin M, Valentin G, et al: Phase 1 pharmacokinetic and pharmacodynamic trial of docetaxel and 17AAG (17-allylamino-17- demethoxygeladanamycin). J Clin Oncol 22:203, 2004 (suppl; abstr 3032)
-
(2004)
J Clin Oncol
, vol.22
, pp. 203
-
-
Solit, D.B.1
Egorin, M.2
Valentin, G.3
-
119
-
-
0038404927
-
Inhibition of heat shock protein 90 function down-regulates Akt kinase and sensitizes tumors to Taxol
-
Solit DB, Basso AD, Olshen AB, et al: Inhibition of heat shock protein 90 function down-regulates Akt kinase and sensitizes tumors to Taxol. Cancer Res 63:2139-2144, 2003
-
(2003)
Cancer Res
, vol.63
, pp. 2139-2144
-
-
Solit, D.B.1
Basso, A.D.2
Olshen, A.B.3
-
120
-
-
0036795180
-
Antibody to vascular endothelial growth factor slows growth of an androgen-independent xenograft model of prostate cancer
-
Fox WD, Higgins B, Maiese KM, et al: Antibody to vascular endothelial growth factor slows growth of an androgen-independent xenograft model of prostate cancer. Clin Cancer Res 8:3226-3231, 2002
-
(2002)
Clin Cancer Res
, vol.8
, pp. 3226-3231
-
-
Fox, W.D.1
Higgins, B.2
Maiese, K.M.3
-
121
-
-
6044259206
-
Tumor cells circulate in the peripheral blood of all major carcinomas but not in healthy subjects or patients with nonmalignant diseases
-
Allard WJ, Matera J, Miller MC, et al: Tumor cells circulate in the peripheral blood of all major carcinomas but not in healthy subjects or patients with nonmalignant diseases. Clin Cancer Res 10:6897-6904, 2004
-
(2004)
Clin Cancer Res
, vol.10
, pp. 6897-6904
-
-
Allard, W.J.1
Matera, J.2
Miller, M.C.3
-
122
-
-
84871466789
-
HER2 imaging as a non-invasive pharmacodynamic marker of Hsp90 inhibition
-
Baltimore, MD, July 10-13
-
Smith-Jones PM, Scher H, Larson SM, et al: HER2 imaging as a non-invasive pharmacodynamic marker of Hsp90 inhibition. 12th SPORE Investigators' Workshop, Baltimore, MD, July 10-13, 2004
-
(2004)
12th SPORE Investigators' Workshop
-
-
Smith-Jones, P.M.1
Scher, H.2
Larson, S.M.3
-
123
-
-
2342599027
-
Tumor localization of 16beta-18F-fluoro-5alpha-dihydrotestosterone versus 18F-FDG in patients with progressive, metastatic prostate cancer
-
Larson SM, Morris M, Gunther I, et al: Tumor localization of 16beta-18F-fluoro-5alpha-dihydrotestosterone versus 18F-FDG in patients with progressive, metastatic prostate cancer. J Nucl Med 45:366-373, 2004
-
(2004)
J Nucl Med
, vol.45
, pp. 366-373
-
-
Larson, S.M.1
Morris, M.2
Gunther, I.3
-
124
-
-
18844385209
-
Androgen deprivation for minimal metastatic disease: The threshold for achieving an undetectable prostate-specific antigen
-
Beekman K, Morris M, Slovin S, et al: Androgen deprivation for minimal metastatic disease: The threshold for achieving an undetectable prostate-specific antigen. Urology 65:947-952, 2005
-
(2005)
Urology
, vol.65
, pp. 947-952
-
-
Beekman, K.1
Morris, M.2
Slovin, S.3
-
125
-
-
22344450775
-
Prostate cancer clinical trial end points: "RECIST"ing a step backwards
-
Scher HI, Morris MJ, Kelly WK, et al: Prostate cancer clinical trial end points: "RECIST"ing a step backwards. Clin Cancer Res 11:5223-32, 2005
-
(2005)
Clin Cancer Res
, vol.11
, pp. 5223-5232
-
-
Scher, H.I.1
Morris, M.J.2
Kelly, W.K.3
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