Reversing effects of lignans on CCl4-induced hepatic CYP450 down regulation by attenuating oxidative stress

Journal of Ethnopharmacology

Volumn 155, Issue 1, 2014, Pages 213-221

  Xie, Yuan ^a   Hao, Haiping ^a   Wang, Hong ^a   Guo, Cen ^a   Kang, An ^a   Wang, Guangji ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

CYP450; Lignan; Liver injury; Oxidative stress

Indexed keywords

1,3 DIOXOLANE DERIVATIVE; 7,7'-DIMETHOXY-(4,4'-BI-1,3-BENZODIOXOLE)-5,5'-DICARBOXYLIC ACID DIMETHYL ESTER; ANTIOXIDANT; CARBON TETRACHLORIDE; CYTOCHROME P450; GAMMA-SCHIZANDRIN; LIGNAN; PLANT EXTRACT; POLYCYCLIC HYDROCARBON;

ANIMAL; CHEMISTRY; DOWN REGULATION; DRUG EFFECTS; ENZYMOLOGY; HEPG2 CELL LINE; HUMAN; ISOLATION AND PURIFICATION; LIVER; LIVER DISEASES; MALE; METABOLISM; OXIDATIVE STRESS; PATHOLOGY; RAT; SCHISANDRA; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIOXIDANTS; CARBON TETRACHLORIDE; CYTOCHROME P-450 ENZYME SYSTEM; DIOXOLES; DOWN-REGULATION; HEP G2 CELLS; HUMANS; LIGNANS; LIVER; LIVER DISEASES; MALE; OXIDATIVE STRESS; PLANT EXTRACTS; POLYCYCLIC COMPOUNDS; RATS; RATS, SPRAGUE-DAWLEY; SCHISANDRA;

EID: 84905097063     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2014.05.016     Document Type: Article

References (43)

1. A.E. Aitken, T.A. Richardson, and E.T. Morgan Regulation of drug-metabolizing enzymes and transporters in inflammation Annual Review of Pharmacology and Toxicology 46 2006 123 149
2. A. Anwar-Mohamed, L.O. Klotz, and A.O. El-Kadi Inhibition of heme oxygenase-1 partially reverses the arsenite-mediated decrease of CYP1A1 CYP1A2, CYP3A23, and CYP3A2 catalytic activity in isolated rat hepatocytes. Drug Metabolism and Disposition 40 2012 504 514
3. 4-induced liver injury by a single dose of retinol Toxicology and Applied Pharmacology 141 1996 507 519
4. R. Barouki, and Y. Morel Repression of cytochrome P450 1A1 gene expression by oxidative stress: mechanisms and biological implications Biochemical Pharmacology 61 2001 511 516
5. 4 in a transfected HepG2 cell line Journal of Pharmacology and Experimental Therapeutics 275 1995 1614 1622
6. J.K. Dammanahalli, and M.W. Duffel Oxidative modification of rat sulfotransferase 1A1 activity in hepatic tissue slices correlates with effects on the purified enzyme Drug Metabolism and Disposition 40 2012 298 303
7. K. Demirdag, I.H. Bahcecioglu, and I.H. Ozercan et al. Role of L-carnitine in the prevention of acute liver damage induced by carbon tetrachloride in rats Journal of Gastroenterology and Hepatology 19 2004 333 338
8. R.B. Drotman, and G.T. Lawhorn Serum enzymes as indicators of chemically induced liver damage Drug and Chemical Toxicology 1 1978 163 171
9. L. Goya, R. Mateos, and L. Bravo Effect of the olive oil phenol hydroxytyrosol on human hepatoma HepG2 cells. Protection against oxidative stress induced by tert-butylhydroperoxide European Journal of Nutrition 46 2007 70 78
10. F.P. Guengerich Cytochrome P-450 3A4: regulation and role in drug metabolism Annual Review of Pharmacology and Toxicology 39 1999 1 17
11. J.L. Hancke, R.A. Burgos, and F. Ahumada Schisandra chinensis-Turcz./ Baill Fitoterapia 1999 20
12. X. Huang, F. Song, and Z. Liu et al. Studies on lignan constituents from Schisandra chinensis (Turcz.) Baill. fruits using high-performance liquid chromatography/electrospray ionization multiple-stage tandem mass spectrometry Journal of Mass Spectrometry 42 2007 1148 1161
13. S.P. Ip, and K.M. Ko The crucial antioxidant action of schisandrin B in protecting against carbon tetrachloride hepatotoxicity in mice: a comparative study with butylated hydroxytoluene Biochemical Pharmacology 52 1996 1687 1693
14. S.P. Ip, M.K. Poon, and C.T. Che et al. Schisandrin B protects against carbon tetrachloride toxicity by enhancing the mitochondrial glutathione redox status in mouse liver Free Radical Biology and Medicine 21 1996 709 712
15. H. Iwata, Y. Tezuka, and S. Kadota et al. Identification and characterization of potent CYP3A4 inhibitors in Schisandra fruit extract Drug Metabolism and Disposition 32 2004 1351 1358
16. N. Jia, X. Liu, and J. Wen et al. A proteomic method for analysis of CYP450s protein expression changes in carbon tetrachloride induced male rat liver microsomes Toxicology 237 2007 1 11
17. T. Kamataki, and H. Kitagawa Effects of EDTA on stability of drug metabolizing enzymes in liver microsomes of rats Chemical & Pharmaceutical Bulletin (Tokyo) 22 1974 1041 1045
18. K.L. Kaul, and R.F. Novak Inhibition and induction of rabbit liver microsomal cytochrome P-450 by pyridine Journal of Pharmacology and Experimental Therapeutics 243 1987 384 390
19. J.Y. Kim, M. Baek, and S. Lee et al. Characterization of the selectivity and mechanism of cytochrome P450 inhibition by dimethyl-4,4′-dimethoxy-5, 6,5′,6′-dimethylenedioxybiphenyl-2,2′-dicarboxylate Drug Metabolism and Disposition 29 2001 1555 1560
20. 4 by partial hepatectomy Toxicologic Pathology 17 1989 494 505
21. 4-treated rats using in vivo CYP1A2 and CYP3A2 contents assessed with the PKCYP test Drug Metabolism and Pharmacokinetics 20 2005 168 176
22. K.M. Kulmatycki, and F. Jamali Drug disease interactions: role of inflammatory mediators in disease and variability in drug response Journal of Pharmacy and Pharmaceutical Sciences 8 2005 602 625
23. Y. Li, S.R. Paranawithana, and J.S. Yoo et al. Induction of liver microsomal cytochrome P-4502B1 by dimethyl diphenyl bicarboxylate in rats Zhongguo Yao Li Xue Bao 13 1992 485 490
24. O.H. Lowry, N.J. Rosebrough, and A.L. Farr et al. Protein measurement with the Folin phenol reagent Journal of Biological Chemistry 193 1951 265 275
25. H. Lu, and G.T. Liu Effect of dibenzo[a,c]cyclooctene lignans isolated from Fructus schizandrae on lipid peroxidation and anti-oxidative enzyme activity Chemico-Biological Interactions 78 1991 77 84
26. 2 and NFI Molecular and Cellular Biology 19 1999 6825 6832
27. E.T. Morgan Regulation of cytochromes P450 during inflammation and infection Drug Metabolism Reviews 29 1997 1129 1188
28. Y. Mu, J. Zhang, and S. Zhang et al. Traditional Chinese medicines Wu Wei Zi (Schisandra chinensis Baill) and Gan Cao (Glycyrrhiza uralensis Fisch) activate pregnane X receptor and increase warfarin clearance in rats Journal of Pharmacology and Experimental Therapeutics 316 2006 1369 1377
29. M. Nakajima, K. Iwata, and T. Yamamoto et al. Nicotine metabolism in liver microsomes from rats with acute hepatitis or cirrhosis Drug Metabolism and Disposition 26 1998 36 41
30. L. Opletal, H. Sovova, and M. Bartlova Dibenzo[a,c]cyclooctadiene lignans of the genus Schisandra: importance, isolation and determination Journal of Chromatography B Analytical Technologies in the Biomedical and Life Sciences 812 2004 357 371
31. M. Ota, N. Sato, and H. Uemura et al. Lowering effect of carbon tetrachloride on microsomal cytochrome P-450 of rat liver Chemico-Biological Interactions 11 1975 265 276
32. S.Y. Pan, Z.L. Yu, and H. Dong et al. Ethanol extract of fructus schisandrae decreases hepatic triglyceride level in mice fed with a high fat/cholesterol diet, with attention to acute toxicity Evidence-Based Complementary and Alternative Medicine 2011 2009 729412
33. M.W. Pfaffl A new mathematical model for relative quantification in real-time RT-PCR Nucleic Acids Research 29 2001 e45
34. F. Qiu, R. Zhang, and J. Sun et al. Inhibitory effects of seven components of danshen extract on catalytic activity of cytochrome P450 enzyme in human liver microsomes Drug Metabolism and Disposition 36 2008 1308 1314
35. R.O. Recknagel, E.A. Glende Jr., and J.A. Dolak et al. Mechanisms of carbon tetrachloride toxicity Pharmacology & Therapeutics 43 1989 139 154
36. Z.H. Shao, C.Q. Li, and T.L. Vanden Hoek et al. Extract from Scutellaria baicalensis Georgi attenuates oxidant stress in cardiomyocytes Journal of Molecular and Cellular Cardiology 31 1999 1885 1895
37. S. Takahashi, T. Takahashi, and S. Mizobuchi et al. Increased cytotoxicity of carbon tetrachloride in a human hepatoma cell line overexpressing cytochrome P450 2E1 Journal of International Medical Research 30 2002 400 405
38. D.J. Waxman P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR Archives of Biochemistry and Biophysics 369 1999 11 23
39. L.W. Weber, M. Boll, and A. Stampfl Hepatotoxicity and mechanism of action of haloalkanes: carbon tetrachloride as a toxicological model Critical Reviews in Toxicology 33 2003 105 136
40. J.P. Whitlock Jr. Induction of cytochrome P4501A1 Annual Review of Pharmacology and Toxicology 39 1999 103 125
41. Y. Xie, H. Hao, and A. Kang et al. Integral pharmacokinetics of multiple lignan components in normal, CCl4-induced hepatic injury and hepatoprotective agents pretreated rats and correlations with hepatic injury biomarkers Journal of Ethnopharmacology 131 2010 290 299
42. Y. Xie, G. Wang, and H. Wang et al. Cytochrome P450 dysregulations in thioacetamide-induced liver cirrhosis in rats and the counteracting effects of hepatoprotective agents Drug Metabolism and Disposition 40 2012 796 802
43. H.K. Yim, Y.S. Jung, and S.Y. Kim et al. Contrasting changes in phase I and phase II metabolism of acetaminophen in male mice pretreated with carbon tetrachloride Basic & Clinical Pharmacology & Toxicology 98 2006 225 230