-
1
-
-
0023264501
-
Locoregional application of 5-fluorouracil to the liver: Alteration of pharmacokinetics and bone marrow toxicity in rats with thioacetamide-induced cirrhosis
-
Aguiar JLA, Berger MR and Frank N (1987) Locoregional application of 5-fluorouracil to the liver: alteration of pharmacokinetics and bone marrow toxicity in rats with thioacetamide-induced cirrhosis. Toxicol Lett 36:181-188.
-
(1987)
Toxicol Lett
, vol.36
, pp. 181-188
-
-
Aguiar, J.L.A.1
Berger, M.R.2
Frank, N.3
-
2
-
-
0002979370
-
Metabolism, pharmacokinetics, and pharmacodynamics of nicotine in man
-
Marton WR, VanLoon GR, Iwamoto ET and Davis L eds Plenum Press, New York
-
Benowitz NL and Jacob P III (1987) Metabolism, pharmacokinetics, and pharmacodynamics of nicotine in man, in Tobacco Smoking and (S)-Nicotine: A Neurobiological Approach (Marton WR, VanLoon GR, Iwamoto ET and Davis L eds) pp 357-373, Plenum Press, New York.
-
(1987)
Tobacco Smoking and (S)-Nicotine: A Neurobiological Approach
, pp. 357-373
-
-
Benowitz, N.L.1
Jacob III, P.2
-
3
-
-
0014751819
-
The metabolism of nicotine into two optically-active stereoisomers of nicotine-1′-oxide by animal tissues in vitro and by cigarette smokers
-
Booth J and Boyland E (1970) The metabolism of nicotine into two optically-active stereoisomers of nicotine-1′-oxide by animal tissues in vitro and by cigarette smokers. Biochem Pharmacol 19:733-742.
-
(1970)
Biochem Pharmacol
, vol.19
, pp. 733-742
-
-
Booth, J.1
Boyland, E.2
-
5
-
-
34250923216
-
Thioacetamid in der experimentellen leberforschung
-
Brodehl J (1961) Thioacetamid in der experimentellen leberforschung. Klin Wochenschr 39: 956-962.
-
(1961)
Klin Wochenschr
, vol.39
, pp. 956-962
-
-
Brodehl, J.1
-
6
-
-
0026702860
-
Metabolism of nicotine by human liver microsomes: Stereoselective formation of. trans-nicotine N′-oxide
-
Cashman JR, Park SB, Yang Z-C, Wrighton SA, Jacob P III and Benowitz NL (1992) Metabolism of nicotine by human liver microsomes: stereoselective formation of. trans-nicotine N′-oxide. Chem Res Toxicol 5:639-646.
-
(1992)
Chem Res Toxicol
, vol.5
, pp. 639-646
-
-
Cashman, J.R.1
Park, S.B.2
Yang, Z.-C.3
Wrighton, S.A.4
Jacob III, P.5
Benowitz, N.L.6
-
7
-
-
0020075617
-
Molecular basis for increased synthesis of albumin in rat liver after thioacetamide
-
Chakrabartty PK, Chattopadhyay SK and Schneider WC (1982) Molecular basis for increased synthesis of albumin in rat liver after thioacetamide. Cancer Res 42:421-428.
-
(1982)
Cancer Res
, vol.42
, pp. 421-428
-
-
Chakrabartty, P.K.1
Chattopadhyay, S.K.2
Schneider, W.C.3
-
8
-
-
0025772069
-
Disposition kinetics and metabolism of nicotine-1′-N-oxide in rabbits
-
Duan MJ, Yu L, Savanapridi C, Jacob P III and Benowitz NL (1991) Disposition kinetics and metabolism of nicotine-1′-N-oxide in rabbits. Drug Metab Dispos 19:667-672.
-
(1991)
Drug Metab Dispos
, vol.19
, pp. 667-672
-
-
Duan, M.J.1
Yu, L.2
Savanapridi, C.3
Jacob III, P.4
Benowitz, N.L.5
-
9
-
-
0001255753
-
Liver tumor in rats fed thiourea or thioacetamide
-
Fizhugh OG and Nelson AA (1948) Liver tumor in rats fed thiourea or thioacetamide. Science (Wash DC) 108:626-628.
-
(1948)
Science (Wash DC)
, vol.108
, pp. 626-628
-
-
Fizhugh, O.G.1
Nelson, A.A.2
-
10
-
-
0025757011
-
Comparison of levels of several human microsomal cytochrome P-450 enzymes and epoxide hydrolase in normal and disease states using immunochemical analysis of surgical liver samples
-
Guengerich FP and Turvy CG (1991) Comparison of levels of several human microsomal cytochrome P-450 enzymes and epoxide hydrolase in normal and disease states using immunochemical analysis of surgical liver samples. J Pharmacol Exp Ther 256:1189-1194.
-
(1991)
J Pharmacol Exp Ther
, vol.256
, pp. 1189-1194
-
-
Guengerich, F.P.1
Turvy, C.G.2
-
11
-
-
0020028678
-
Estimation of isozymes of microsomal cytochrome P-450 in rats, rabbits and humans using immunochemical staining coupled with sodium dodecyl sulfate-polyacrylamide gel electrophoresis
-
Guengerich FP, Wang P and Davidson NK (1982) Estimation of isozymes of microsomal cytochrome P-450 in rats, rabbits and humans using immunochemical staining coupled with sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Biochemistry 21:1698-1706.
-
(1982)
Biochemistry
, vol.21
, pp. 1698-1706
-
-
Guengerich, F.P.1
Wang, P.2
Davidson, N.K.3
-
12
-
-
0025812823
-
Metabolism of nicotine by rat liver cytochrome P-450: Assessment utilizing monoclonal antibodies to nicotine and cotinine
-
Hammond DK, Bjercke RJ, Langone JJ and Strobel HW (1991) Metabolism of nicotine by rat liver cytochrome P-450: assessment utilizing monoclonal antibodies to nicotine and cotinine. Drug Metab Dispos 19:804-808.
-
(1991)
Drug Metab Dispos
, vol.19
, pp. 804-808
-
-
Hammond, D.K.1
Bjercke, R.J.2
Langone, J.J.3
Strobel, H.W.4
-
13
-
-
0025944787
-
Age-dependent expression of cytochrome P-450s in rat liver
-
Imaoka S, Fujita S and Funae Y (1991) Age-dependent expression of cytochrome P-450s in rat liver. Biochim Biophys Acta 1097:187-192.
-
(1991)
Biochim Biophys Acta
, vol.1097
, pp. 187-192
-
-
Imaoka, S.1
Fujita, S.2
Funae, Y.3
-
14
-
-
0025305212
-
Changes in the amount of cytochrome P450s in rat hepatic microsomes with starvation
-
Imaoka S, Terano Y and Funae Y (1990) Changes in the amount of cytochrome P450s in rat hepatic microsomes with starvation. Arch Biochem Biophys 278:168-178.
-
(1990)
Arch Biochem Biophys
, vol.278
, pp. 168-178
-
-
Imaoka, S.1
Terano, Y.2
Funae, Y.3
-
15
-
-
0027162358
-
Changes in the amounts of cytochromes P450 in rat hepatic microsomes produced by cyclosporin A
-
Isogai M, Shimada N, Kamataki T, Imaoka S and Funae Y (1993) Changes in the amounts of cytochromes P450 in rat hepatic microsomes produced by cyclosporin A. Xenobiotica 23: 799-807.
-
(1993)
Xenobiotica
, vol.23
, pp. 799-807
-
-
Isogai, M.1
Shimada, N.2
Kamataki, T.3
Imaoka, S.4
Funae, Y.5
-
17
-
-
0025347025
-
Immunopathology of acute galactosamine hepatitis in rats
-
Jonker AM, Dijkhuis FWJ, Kroese FGM, Hardonk MJ and Grond J (1990) Immunopathology of acute galactosamine hepatitis in rats. Hepatology 11:622-627.
-
(1990)
Hepatology
, vol.11
, pp. 622-627
-
-
Jonker, A.M.1
Dijkhuis, F.W.J.2
Kroese, F.G.M.3
Hardonk, M.J.4
Grond, J.5
-
18
-
-
0016260282
-
5 and cytochrome P-450 and aniline-induced P-450 difference spectrum
-
5 and cytochrome P-450 and aniline-induced P-450 difference spectrum. Jpn J Pharmacol 24:195-203.
-
(1974)
Jpn J Pharmacol
, vol.24
, pp. 195-203
-
-
Kamataki, T.1
Kitagawa, H.2
-
19
-
-
0017740180
-
Spleno-hepatoplasty in rats with chemically-induced cirrhosis of the liver
-
Kasahara Y (1977) Spleno-hepatoplasty in rats with chemically-induced cirrhosis of the liver. Arch Jpn Chir 46:335-360.
-
(1977)
Arch Jpn Chir
, vol.46
, pp. 335-360
-
-
Kasahara, Y.1
-
20
-
-
0025999075
-
Decreased estradiol receptor concentrations in ethionine-induced fatty liver of rats
-
Katoh N, Shimbayashi K, Abe K and Sakurada K (1991) Decreased estradiol receptor concentrations in ethionine-induced fatty liver of rats. Toxicol Lett 58:279-285.
-
(1991)
Toxicol Lett
, vol.58
, pp. 279-285
-
-
Katoh, N.1
Shimbayashi, K.2
Abe, K.3
Sakurada, K.4
-
21
-
-
0026640574
-
The topography of trifluoroacetylated protein antigens in liver microsomal fractions from halothane-treated rats
-
Kenna JG, Martin JL and Pohl LR (1992) The topography of trifluoroacetylated protein antigens in liver microsomal fractions from halothane-treated rats. Biochem Pharmacol 44:621-629.
-
(1992)
Biochem Pharmacol
, vol.44
, pp. 621-629
-
-
Kenna, J.G.1
Martin, J.L.2
Pohl, L.R.3
-
23
-
-
0015963597
-
Selective uridine triphosphate deficiency induced by D-galactosamine in liver and reversed by pyrimidine nucleotide precursors
-
Keppler DOR, Pausch J and Decker K (1974) Selective uridine triphosphate deficiency induced by D-galactosamine in liver and reversed by pyrimidine nucleotide precursors. J Biol Chem 249:211-216.
-
(1974)
J Biol Chem
, vol.249
, pp. 211-216
-
-
Keppler, D.O.R.1
Pausch, J.2
Decker, K.3
-
24
-
-
0024215380
-
Sexual dimorphism of nicotine metabolism and distribution in the rat: Studies in vivo and in vitro
-
Kyerematen GA, Owens GF, Chattopadhyay B, deBethizy JD and Vesell ES (1988) Sexual dimorphism of nicotine metabolism and distribution in the rat: studies in vivo and in vitro. Drug Metab Dispos 16:823-828.
-
(1988)
Drug Metab Dispos
, vol.16
, pp. 823-828
-
-
Kyerematen, G.A.1
Owens, G.F.2
Chattopadhyay, B.3
DeBethizy, J.D.4
Vesell, E.S.5
-
26
-
-
0014949207
-
Cleavage of structure proteins during the assembly of the head of bacteriophage T4
-
Laemmli UK (1970) Cleavage of structure proteins during the assembly of the head of bacteriophage T4. Nature (Lond) 227:680-685.
-
(1970)
Nature (Lond)
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
28
-
-
8044258385
-
Role of human CYP2A6 in C-oxidation of nicotine
-
Nakajima M, Yamamoto T, Nunoya K, Yokoi T, Nagashima K, Inoue K, Funae Y, Shimada N, Kamataki T and Kuroiwa Y (1996) Role of human CYP2A6 in C-oxidation of nicotine. Drug Metab Dispos 24:1212-1217.
-
(1996)
Drug Metab Dispos
, vol.24
, pp. 1212-1217
-
-
Nakajima, M.1
Yamamoto, T.2
Nunoya, K.3
Yokoi, T.4
Nagashima, K.5
Inoue, K.6
Funae, Y.7
Shimada, N.8
Kamataki, T.9
Kuroiwa, Y.10
-
30
-
-
0027310629
-
Nicotine metabolism by rat hepatic cytochrome P450s
-
Nakayama H, Okuda H, Nakashima T, Imaoka S and Funae Y (1993) Nicotine metabolism by rat hepatic cytochrome P450s. Biochem Pharmacol 45:2554-2556.
-
(1993)
Biochem Pharmacol
, vol.45
, pp. 2554-2556
-
-
Nakayama, H.1
Okuda, H.2
Nakashima, T.3
Imaoka, S.4
Funae, Y.5
-
31
-
-
0027158243
-
Changes in microsomal phospholipases and arachidonic acid in experimental alcoholic liver injury: Relationship to cytochrome P-450 2E1 induction and conjugated diene formation
-
Nanji AA, Zhao S, Lamb RG, Sadrzadeh SMH, Dannenberg AJ and Waxman DJ (1993) Changes in microsomal phospholipases and arachidonic acid in experimental alcoholic liver injury: relationship to cytochrome P-450 2E1 induction and conjugated diene formation. Alcohol Clin Exp Res 17:598-603.
-
(1993)
Alcohol Clin Exp Res
, vol.17
, pp. 598-603
-
-
Nanji, A.A.1
Zhao, S.2
Lamb, R.G.3
Sadrzadeh, S.M.H.4
Dannenberg, A.J.5
Waxman, D.J.6
-
32
-
-
78651165715
-
The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature
-
Omura T and Sato R (1964a) The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature. J Biol Chem 239:2370-2378.
-
(1964)
J Biol Chem
, vol.239
, pp. 2370-2378
-
-
Omura, T.1
Sato, R.2
-
33
-
-
50449100139
-
The carbon monoxide-binding pigment of liver microsomes. II. Solubilization, purification, and properties
-
Omura T and Sato R (1964b) The carbon monoxide-binding pigment of liver microsomes. II. Solubilization, purification, and properties. J Biol Chem 239:2379-2385.
-
(1964)
J Biol Chem
, vol.239
, pp. 2379-2385
-
-
Omura, T.1
Sato, R.2
-
34
-
-
0029777543
-
Effects of liver diseases on drug metabolism
-
Paintaud G, Bechtel Y, Brientini M-P, Miguet J-P and Bechtel PR (1996) Effects of liver diseases on drug metabolism. Therapie 51:384-389.
-
(1996)
Therapie
, vol.51
, pp. 384-389
-
-
Paintaud, G.1
Bechtel, Y.2
Brientini, M.-P.3
Miguet, J.-P.4
Bechtel, P.R.5
-
35
-
-
0023062492
-
D-Galactosamine induced changes in rat liver plasma membrane lipid composition and some enzyme activities
-
Petkova DH, Momchilova AB, Markovska TT and Koumanov KS (1987) D-Galactosamine induced changes in rat liver plasma membrane lipid composition and some enzyme activities. Int J Biochem 19:289-291.
-
(1987)
Int J Biochem
, vol.19
, pp. 289-291
-
-
Petkova, D.H.1
Momchilova, A.B.2
Markovska, T.T.3
Koumanov, K.S.4
-
36
-
-
73849173955
-
Hepatic triphosphopyridine nucleotide-cytochrome c reductase: Isolation, characterization, and kinetic studies
-
Phillips AH and Langdon RG (1962) Hepatic triphosphopyridine nucleotide-cytochrome c reductase: isolation, characterization, and kinetic studies. J Biol Chem 237:2652-2660.
-
(1962)
J Biol Chem
, vol.237
, pp. 2652-2660
-
-
Phillips, A.H.1
Langdon, R.G.2
-
37
-
-
0020512769
-
Controlled induction of cirrhosis in the rat
-
Proctor E and Chatamra K (1983) Controlled induction of cirrhosis in the rat. Br J Exp Pathol 64:320-330.
-
(1983)
Br J Exp Pathol
, vol.64
, pp. 320-330
-
-
Proctor, E.1
Chatamra, K.2
-
38
-
-
0027533282
-
High-performance liquid chromatographic determination of nicotine and its urinary metabolites via their 1,3-diethyl-2-thiobarbituric acid derivatives
-
Rustemeier K, Demetrios D, Schepers G and Voncken P (1993) High-performance liquid chromatographic determination of nicotine and its urinary metabolites via their 1,3-diethyl-2-thiobarbituric acid derivatives. J Chromatogr 613:95-103.
-
(1993)
J Chromatogr
, vol.613
, pp. 95-103
-
-
Rustemeier, K.1
Demetrios, D.2
Schepers, G.3
Voncken, P.4
-
40
-
-
0024269123
-
Cotinine determination by immunoassays may be influenced by other nicotine metabolites
-
Schepers G and Walk R-A (1988) Cotinine determination by immunoassays may be influenced by other nicotine metabolites. Arch Toxicol 62:395-397.
-
(1988)
Arch Toxicol
, vol.62
, pp. 395-397
-
-
Schepers, G.1
Walk, R.-A.2
-
42
-
-
0018893322
-
Measurement of hepatic drug-metabolizing enzyme activity in man
-
Sotaniemi EA, Pelkonen RO and Puukka M (1980) Measurement of hepatic drug-metabolizing enzyme activity in man. Eur J Clin Pharmacol 17:267-274.
-
(1980)
Eur J Clin Pharmacol
, vol.17
, pp. 267-274
-
-
Sotaniemi, E.A.1
Pelkonen, R.O.2
Puukka, M.3
-
43
-
-
0022256154
-
Isolation and analysis of N-oxide metabolites of tertiary amines: Quantitation of nicotine-1′-N-oxide formation in mice
-
Thompson JA, Norris KJ and Petersen DR (1985) Isolation and analysis of N-oxide metabolites of tertiary amines: quantitation of nicotine-1′-N-oxide formation in mice. J Chromatogr 341:349-359.
-
(1985)
J Chromatogr
, vol.341
, pp. 349-359
-
-
Thompson, J.A.1
Norris, K.J.2
Petersen, D.R.3
-
44
-
-
0027459176
-
Prevention of galactosamine-induced hepatic damage by picroliv: Study on bile flow and isolated hepatocytes (ex vivo)
-
Visen PKS, Shukla B, Patnaik GK and Dhawan BN (1993) Prevention of galactosamine-induced hepatic damage by picroliv: study on bile flow and isolated hepatocytes (ex vivo). Planta Med 59:37-41.
-
(1993)
Planta Med
, vol.59
, pp. 37-41
-
-
Visen, P.K.S.1
Shukla, B.2
Patnaik, G.K.3
Dhawan, B.N.4
-
45
-
-
0024401356
-
Capillary gas chromatographic determination of trans-3′-hydroxycotinine simultaneously with nicotine and cotinine in urine and blood samples
-
Voncken P, Schepers G and Schäfer K-H (1989) Capillary gas chromatographic determination of trans-3′-hydroxycotinine simultaneously with nicotine and cotinine in urine and blood samples. J Chromatogr 479:410-418.
-
(1989)
J Chromatogr
, vol.479
, pp. 410-418
-
-
Voncken, P.1
Schepers, G.2
Schäfer, K.-H.3
|