-
1
-
-
79251623365
-
Diabetes mellitus and Alzheimer's disease: Shared pathology and treatment?
-
K. Akter, E.A. Lanza, S.A. Martin, N. Myronyuk, M. Rua, and R.B. Raffa Diabetes mellitus and Alzheimer's disease: shared pathology and treatment? Br. J. Clin. Pharmacol. 71 2011 365 376
-
(2011)
Br. J. Clin. Pharmacol.
, vol.71
, pp. 365-376
-
-
Akter, K.1
Lanza, E.A.2
Martin, S.A.3
Myronyuk, N.4
Rua, M.5
Raffa, R.B.6
-
2
-
-
33646534207
-
Beta-amyloid mediated nitration of manganese superoxide dismutase: Implication for oxidative stress in a APPNLH/NLH X PS-1P264L/P264L double knock-in mouse model of Alzheimer's disease
-
M. Anantharaman, J. Tangpong, J.N. Keller, M.P. Murphy, W.R. Markesbery, K.K. Kiningham St, and D.K. Clair Beta-amyloid mediated nitration of manganese superoxide dismutase: implication for oxidative stress in a APPNLH/NLH X PS-1P264L/P264L double knock-in mouse model of Alzheimer's disease Am. J. Pathol. 168 2006 1608 1618
-
(2006)
Am. J. Pathol.
, vol.168
, pp. 1608-1618
-
-
Anantharaman, M.1
Tangpong, J.2
Keller, J.N.3
Murphy, M.P.4
Markesbery, W.R.5
Kiningham St, K.K.6
Clair, D.K.7
-
3
-
-
0026695045
-
Light and electron microscopic localization of beta-amyloid protein in muscle biopsies of patients with inclusion-body myositis
-
V. Askanas, W.K. Engel, and R.B. Alvarez Light and electron microscopic localization of beta-amyloid protein in muscle biopsies of patients with inclusion-body myositis Am. J. Pathol. 141 1992 31 36
-
(1992)
Am. J. Pathol.
, vol.141
, pp. 31-36
-
-
Askanas, V.1
Engel, W.K.2
Alvarez, R.B.3
-
4
-
-
0029671441
-
Transfer of beta-amyloid precursor protein gene using adenovirus vector causes mitochondrial abnormalities in cultured normal human muscle
-
V. Askanas, J. McFerrin, S. Baque, R.B. Alvarez, E. Sarkozi, and W.K. Engel Transfer of beta-amyloid precursor protein gene using adenovirus vector causes mitochondrial abnormalities in cultured normal human muscle Proc. Natl. Acad. Sci. USA. 93 1996 1314 1319
-
(1996)
Proc. Natl. Acad. Sci. USA.
, vol.93
, pp. 1314-1319
-
-
Askanas, V.1
McFerrin, J.2
Baque, S.3
Alvarez, R.B.4
Sarkozi, E.5
Engel, W.K.6
-
5
-
-
0035145398
-
Inclusion-body myositis: Newest concepts of pathogenesis and relation to aging and Alzheimer disease
-
V. Askanas, and W.K. Engel Inclusion-body myositis: newest concepts of pathogenesis and relation to aging and Alzheimer disease J Neuropathol. Exp. Neurol. 60 2001 1 14
-
(2001)
J Neuropathol. Exp. Neurol.
, vol.60
, pp. 1-14
-
-
Askanas, V.1
Engel, W.K.2
-
6
-
-
33644749222
-
AMPA receptor downscaling at the onset of Alzheimer's disease pathology in double knockin mice
-
E.H. Chang, M.J. Savage, D.G. Flood, J.M. Thomas, R.B. Levy, V. Mahadomrongkul, T. Shirao, C. Aoki, and P.T. Huerta AMPA receptor downscaling at the onset of Alzheimer's disease pathology in double knockin mice Proc. Natl. Acad. Sci. USA 103 2006 3410 3415
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 3410-3415
-
-
Chang, E.H.1
Savage, M.J.2
Flood, D.G.3
Thomas, J.M.4
Levy, R.B.5
Mahadomrongkul, V.6
Shirao, T.7
Aoki, C.8
Huerta, P.T.9
-
7
-
-
1242316296
-
Insulin and neurodegenerative disease: Shared and specific mechanisms
-
S. Craft, and G.S. Watson Insulin and neurodegenerative disease: shared and specific mechanisms Lancet Neurol. 3 2004 169 178
-
(2004)
Lancet Neurol.
, vol.3
, pp. 169-178
-
-
Craft, S.1
Watson, G.S.2
-
8
-
-
34147173277
-
Insulin resistance and Alzheimer's disease pathogenesis: Potential mechanisms and implications for treatment
-
S. Craft Insulin resistance and Alzheimer's disease pathogenesis: potential mechanisms and implications for treatment Curr Alzheimer Res. 4 2007 147 152
-
(2007)
Curr Alzheimer Res.
, vol.4
, pp. 147-152
-
-
Craft, S.1
-
9
-
-
0031772229
-
Amyloid-beta deposition in skeletal muscle of transgenic mice: Possible model of inclusion body myopathy
-
K. Fukuchi, D. Pham, M. Hart, L. Li, and J.R. Lindsey Amyloid-beta deposition in skeletal muscle of transgenic mice: possible model of inclusion body myopathy Am. J. Pathol. 153 1998 1687 1693
-
(1998)
Am. J. Pathol.
, vol.153
, pp. 1687-1693
-
-
Fukuchi, K.1
Pham, D.2
Hart, M.3
Li, L.4
Lindsey, J.R.5
-
10
-
-
0035943436
-
Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils
-
J. Gotz, F. Chen, J. van Dorpe, and R.M. Nitsch Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils Science 293 2001 1491 1495
-
(2001)
Science
, vol.293
, pp. 1491-1495
-
-
Gotz, J.1
Chen, F.2
Van Dorpe, J.3
Nitsch, R.M.4
-
11
-
-
46749091229
-
Ketone bodies as a therapeutic for Alzheimer's disease
-
S.T. Henderson Ketone bodies as a therapeutic for Alzheimer's disease Neurotherapeutics 5 2008 470 480
-
(2008)
Neurotherapeutics
, vol.5
, pp. 470-480
-
-
Henderson, S.T.1
-
12
-
-
83455164148
-
BACE2 expression increases in human neurodegenerative disease
-
C.J. Holler, R.L. Webb, A.L. Laux, T.L. Beckett, D.M. Niedowicz, R.R. Ahmed, Y. Liu, C.R. Simmons, A.L. Dowling, A. Spinelli, M. Khurgel, S. Estus, E. Head, L.B. Hersh, and M.P. Murphy BACE2 expression increases in human neurodegenerative disease Am. J. Pathol. 180 2012 337 350
-
(2012)
Am. J. Pathol.
, vol.180
, pp. 337-350
-
-
Holler, C.J.1
Webb, R.L.2
Laux, A.L.3
Beckett, T.L.4
Niedowicz, D.M.5
Ahmed, R.R.6
Liu, Y.7
Simmons, C.R.8
Dowling, A.L.9
Spinelli, A.10
Khurgel, M.11
Estus, S.12
Head, E.13
Hersh, L.B.14
Murphy, M.P.15
-
13
-
-
58149339635
-
Amyloid-beta peptide (Abeta) neurotoxicity is modulated by the rate of peptide aggregation: A beta dimers and trimers correlate with neurotoxicity
-
L.W. Hung, G.D. Ciccotosto, E. Giannakis, D.J. Tew, K. Perez, C.L. Masters, R. Cappai, J.D. Wade, and K.J. Barnham Amyloid-beta peptide (Abeta) neurotoxicity is modulated by the rate of peptide aggregation: a beta dimers and trimers correlate with neurotoxicity J Neurosci. 28 2008 11950 11958
-
(2008)
J Neurosci.
, vol.28
, pp. 11950-11958
-
-
Hung, L.W.1
Ciccotosto, G.D.2
Giannakis, E.3
Tew, D.J.4
Perez, K.5
Masters, C.L.6
Cappai, R.7
Wade, J.D.8
Barnham, K.J.9
-
14
-
-
0031740915
-
Transgenic mice over-expressing the C-99 fragment of betaPP with an alpha-secretase site mutation develop a myopathy similar to human inclusion body myositis
-
L.W. Jin, M.G. Hearn, C.E. Ogburn, N. Dang, D. Nochlin, W.C. Ladiges, and G.M. Martin Transgenic mice over-expressing the C-99 fragment of betaPP with an alpha-secretase site mutation develop a myopathy similar to human inclusion body myositis Am. J. Pathol. 153 1998 1679 1686
-
(1998)
Am. J. Pathol.
, vol.153
, pp. 1679-1686
-
-
Jin, L.W.1
Hearn, M.G.2
Ogburn, C.E.3
Dang, N.4
Nochlin, D.5
Ladiges, W.C.6
Martin, G.M.7
-
15
-
-
79955484857
-
Abeta(1-42) inhibition of LTP is mediated by a signaling pathway involving caspase-3, Akt1 and GSK-3beta
-
J. Jo, D.J. Whitcomb, K.M. Olsen, T.L. Kerrigan, S.C. Lo, G. Bru-Mercier, B. Dickinson, S. Scullion, M. Sheng, G. Collingridge, and K. Cho Abeta(1-42) inhibition of LTP is mediated by a signaling pathway involving caspase-3, Akt1 and GSK-3beta Nat. Neurosci. 14 2011 545 547
-
(2011)
Nat. Neurosci.
, vol.14
, pp. 545-547
-
-
Jo, J.1
Whitcomb, D.J.2
Olsen, K.M.3
Kerrigan, T.L.4
Lo, S.C.5
Bru-Mercier, G.6
Dickinson, B.7
Scullion, S.8
Sheng, M.9
Collingridge, G.10
Cho, K.11
-
16
-
-
0034624968
-
D-beta-hydroxybutyrate protects neurons in models of Alzheimer's and Parkinson's disease
-
Y. Kashiwaya, T. Takeshima, N. Mori, K. Nakashima, K. Clarke, and R.L. Veech D-beta-hydroxybutyrate protects neurons in models of Alzheimer's and Parkinson's disease Proc. Natl. Acad. Sci. USA 97 2000 5440 5444
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 5440-5444
-
-
Kashiwaya, Y.1
Takeshima, T.2
Mori, N.3
Nakashima, K.4
Clarke, K.5
Veech, R.L.6
-
17
-
-
84875240585
-
A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease
-
Y. Kashiwaya, C. Bergman, J.H. Lee, R. Wan, M. Todd King, M.R. Mughal, E. Okun, K. Clarke, M.P. Mattson, and R.L Veech A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease Neurobiol. Ageing 2012
-
(2012)
Neurobiol. Ageing
-
-
Kashiwaya, Y.1
Bergman, C.2
Lee, J.H.3
Wan, R.4
Todd King, M.5
Mughal, M.R.6
Okun, E.7
Clarke, K.8
Mattson, M.P.9
Veech, R.L.10
-
18
-
-
17944382037
-
Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP
-
J. Lewis, D.W. Dickson, W.L. Lin, L. Chisholm, A. Corral, G. Jones, S.H. Yen, N. Sahara, L. Skipper, D. Yager, C. Eckman, J. Hardy, M. Hutton, and E. McGowan Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP Science 293 2001 1487 1491
-
(2001)
Science
, vol.293
, pp. 1487-1491
-
-
Lewis, J.1
Dickson, D.W.2
Lin, W.L.3
Chisholm, L.4
Corral, A.5
Jones, G.6
Yen, S.H.7
Sahara, N.8
Skipper, L.9
Yager, D.10
Eckman, C.11
Hardy, J.12
Hutton, M.13
McGowan, E.14
-
19
-
-
33746916488
-
Proteomic analysis of inclusion body myositis
-
J. Li, C. Yin, H. Okamoto, H. Jaffe, E.H. Oldfield, Z. Zhuang, A.O. Vortmeyer, and E.J. Rushing Proteomic analysis of inclusion body myositis J. Neuropathol. Exp. Neurol. 65 2006 826 833
-
(2006)
J. Neuropathol. Exp. Neurol.
, vol.65
, pp. 826-833
-
-
Li, J.1
Yin, C.2
Okamoto, H.3
Jaffe, H.4
Oldfield, E.H.5
Zhuang, Z.6
Vortmeyer, A.O.7
Rushing, E.J.8
-
20
-
-
33645106304
-
Mutations in amyloid precursor protein and presenilin-1 genes increase the basal oxidative stress in murine neuronal cells and lead to increased sensitivity to oxidative stress mediated by amyloid beta-peptide (1-42), HO and kainic acid: Implications for Alzheimer's disease
-
H. Mohmmad Abdul, R. Sultana, J.N. Keller, D.K. St Clair, W.R. Markesbery, and D.A. Butterfield Mutations in amyloid precursor protein and presenilin-1 genes increase the basal oxidative stress in murine neuronal cells and lead to increased sensitivity to oxidative stress mediated by amyloid beta-peptide (1-42), HO and kainic acid: implications for Alzheimer's disease J. Neurochem. 96 2006 1322 1335
-
(2006)
J. Neurochem.
, vol.96
, pp. 1322-1335
-
-
Mohmmad Abdul, H.1
Sultana, R.2
Keller, J.N.3
St Clair, D.K.4
Markesbery, W.R.5
Butterfield, D.A.6
-
21
-
-
34548253353
-
Abeta solubility and deposition during AD progression and in APPxPS-1 knock-in mice
-
M.P. Murphy, T.L. Beckett, Q. Ding, E. Patel, W.R. Markesbery St, D.K. Clair, H. LeVine 3rd, and J.N. Keller Abeta solubility and deposition during AD progression and in APPxPS-1 knock-in mice Neurobiol. Dis. 27 2007 301 311
-
(2007)
Neurobiol. Dis.
, vol.27
, pp. 301-311
-
-
Murphy, M.P.1
Beckett, T.L.2
Ding, Q.3
Patel, E.4
Markesbery St, W.R.5
Clair, D.K.6
Levine III, H.7
Keller, J.N.8
-
22
-
-
0029788661
-
Enhanced amyloidogenic processing of the beta-amyloid precursor protein in gene-targeted mice bearing the Swedish familial Alzheimer's disease mutations and a humanized Abeta sequence
-
A.G. Reaume, D.S. Howland, S.P. Trusko, M.J. Savage, D.M. Lang, B.D. Greenberg, R. Siman, and R.W. Scott Enhanced amyloidogenic processing of the beta-amyloid precursor protein in gene-targeted mice bearing the Swedish familial Alzheimer's disease mutations and a humanized Abeta sequence J. Biol. Chem. 271 1996 23380 23388
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 23380-23388
-
-
Reaume, A.G.1
Howland, D.S.2
Trusko, S.P.3
Savage, M.J.4
Lang, D.M.5
Greenberg, B.D.6
Siman, R.7
Scott, R.W.8
-
23
-
-
0027232988
-
Beta-Amyloid precursor protein mRNA is increased in inclusion-body myositis muscle
-
E. Sarkozi, V. Askanas, S.A. Johnson, W.K. Engel, and R.B. Alvarez beta-Amyloid precursor protein mRNA is increased in inclusion-body myositis muscle Neuroreport 4 1993 815 818
-
(1993)
Neuroreport
, vol.4
, pp. 815-818
-
-
Sarkozi, E.1
Askanas, V.2
Johnson, S.A.3
Engel, W.K.4
Alvarez, R.B.5
-
24
-
-
0034551780
-
Presenilin-1 P264L knock-in mutation: Differential effects on abeta production, amyloid deposition, and neuronal vulnerability
-
R. Siman, A.G. Reaume, M.J. Savage, S. Trusko, Y.G. Lin, R.W. Scott, and D.G. Flood Presenilin-1 P264L knock-in mutation: differential effects on abeta production, amyloid deposition, and neuronal vulnerability J. Neurosci. 20 2000 8717 8726
-
(2000)
J. Neurosci.
, vol.20
, pp. 8717-8726
-
-
Siman, R.1
Reaume, A.G.2
Savage, M.J.3
Trusko, S.4
Lin, Y.G.5
Scott, R.W.6
Flood, D.G.7
-
25
-
-
48849092902
-
Induction of ketosis may improve mitochondrial function and decrease steady-state amyloid-beta precursor protein (APP) levels in the aged dog
-
C.M. Studzinski, W.A. MacKay, T.L. Beckett, S.T. Henderson, M.P. Murphy, P.G. Sullivan, and W.M. Burnham Induction of ketosis may improve mitochondrial function and decrease steady-state amyloid-beta precursor protein (APP) levels in the aged dog Brain Res. 1226 2008 209 217
-
(2008)
Brain Res.
, vol.1226
, pp. 209-217
-
-
Studzinski, C.M.1
MacKay, W.A.2
Beckett, T.L.3
Henderson, S.T.4
Murphy, M.P.5
Sullivan, P.G.6
Burnham, W.M.7
-
26
-
-
58549095944
-
Effects of short-term Western diet on cerebral oxidative stress and diabetes related factors in APP x PS1 knock-in mice
-
C.M. Studzinski, F. Li, A.J. Bruce-Keller, S.O. Fernandez-Kim, L. Zhang, A.M. Weidner, W.R. Markesbery, M.P. Murphy, and J.N. Keller Effects of short-term Western diet on cerebral oxidative stress and diabetes related factors in APP x PS1 knock-in mice J. Neurochem. 108 2009 860 866
-
(2009)
J. Neurochem.
, vol.108
, pp. 860-866
-
-
Studzinski, C.M.1
Li, F.2
Bruce-Keller, A.J.3
Fernandez-Kim, S.O.4
Zhang, L.5
Weidner, A.M.6
Markesbery, W.R.7
Murphy, M.P.8
Keller, J.N.9
-
27
-
-
27744549328
-
A ketogenic diet reduces amyloid beta 40 and 42 in a mouse model of Alzheimer's disease
-
I. Van der Auwera, S. Wera, F. Van Leuven, and S.T. Henderson A ketogenic diet reduces amyloid beta 40 and 42 in a mouse model of Alzheimer's disease Nutr. Metab. 2 2005 28
-
(2005)
Nutr. Metab.
, vol.2
, pp. 28
-
-
Van Der Auwera, I.1
Wera, S.2
Van Leuven, F.3
Henderson, S.T.4
-
28
-
-
0033809909
-
Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the london mutant of human APP in neurons
-
J. Van Dorpe, L. Smeijers, I. Dewachter, D. Nuyens, K. Spittaels, C. Van Den Haute, M. Mercken, D. Moechars, I. Laenen, C. Kuiperi, K. Bruynseels, I. Tesseur, R. Loos, H. Vanderstichele, F. Checler, R. Sciot, and F. Van Leuven Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the london mutant of human APP in neurons Am. J. Pathol. 157 2000 1283 1298
-
(2000)
Am. J. Pathol.
, vol.157
, pp. 1283-1298
-
-
Van Dorpe, J.1
Smeijers, L.2
Dewachter, I.3
Nuyens, D.4
Spittaels, K.5
Van Den Haute, C.6
Mercken, M.7
Moechars, D.8
Laenen, I.9
Kuiperi, C.10
Bruynseels, K.11
Tesseur, I.12
Loos, R.13
Vanderstichele, H.14
Checler, F.15
Sciot, R.16
Van Leuven, F.17
-
29
-
-
1042299789
-
The therapeutic implications of ketone bodies: The effects of ketone bodies in pathological conditions: Ketosis, ketogenic diet, redox states, insulin resistance, and mitochondrial metabolism
-
R.L. Veech The therapeutic implications of ketone bodies: the effects of ketone bodies in pathological conditions: ketosis, ketogenic diet, redox states, insulin resistance, and mitochondrial metabolism Prostaglandins Leukot Essent Fatty Acids. 70 2004 309 319
-
(2004)
Prostaglandins Leukot Essent Fatty Acids.
, vol.70
, pp. 309-319
-
-
Veech, R.L.1
-
30
-
-
0037041426
-
Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo
-
D.M. Walsh, I. Klyubin, J.V. Fadeeva, W.K. Cullen, R. Anwyl, M.S. Wolfe, M.J. Rowan, and D.J. Selkoe Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo Nature 416 2002 535 539
-
(2002)
Nature
, vol.416
, pp. 535-539
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
Cullen, W.K.4
Anwyl, R.5
Wolfe, M.S.6
Rowan, M.J.7
Selkoe, D.J.8
-
31
-
-
33845217281
-
AbetaPP-overexpression and proteasome inhibition increase alphaB-crystallin in cultured human muscle: Relevance to inclusion-body myositis
-
S. Wojcik, W.K. Engel, J. McFerrin, O. Paciello, and V. Askanas AbetaPP-overexpression and proteasome inhibition increase alphaB-crystallin in cultured human muscle: relevance to inclusion-body myositis Neuromuscul. Disord. 16 2006 839 844
-
(2006)
Neuromuscul. Disord.
, vol.16
, pp. 839-844
-
-
Wojcik, S.1
Engel, W.K.2
McFerrin, J.3
Paciello, O.4
Askanas, V.5
|