Rapid β-amyloid deposition and cognitive impairment after cholinergic denervation in APP/PS1 mice

Journal of Neuropathology and Experimental Neurology

Volumn 72, Issue 4, 2013, Pages 272-285

  Ramos Rodriguez, Juan Jose ^a   Pacheco Herrero, Mar ^a   Thyssen, Diana ^b   Murillo Carretero, Maria Isabel ^a   Berrocoso, Esther ^c,d   Spires Jones, Tara L ^b   Bacskai, Brian J ^b   Garcia Alloza, Monica ^a  

^a UNIVERSITY OF CÁDIZ   (Spain)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c UNIVERSITY OF CÁDIZ   (Spain)

^d CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE SALUD MENTAL CIBERSAM   (Spain)

Author keywords

amyloid; Alzheimer disease; Basal forebrain; Cholinergic system; Murine p75NTR saporin; Senile plaques

Indexed keywords

AMYLOID BETA PROTEIN; IMMUNOTOXIN; TAU PROTEIN; AMYLOID PRECURSOR PROTEIN; PRESENILIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTONOMIC DENERVATION; AUTONOMIC INNERVATION; BRAIN CORTEX; BRAIN DAMAGE; BRAIN REGION; CHOLINERGIC SYSTEM; COGNITIVE DEFECT; CONTROLLED STUDY; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MEMORY; MOUSE; MULTIPHOTON MICROSCOPY; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SPATIAL LEARNING; TRANSGENE; ANIMAL; CHOLINERGIC NERVE CELL; DENERVATION; GENETICS; METHODOLOGY; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; TIME; TRANSGENIC MOUSE;

AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CEREBRAL CORTEX; CHOLINERGIC NEURONS; COGNITION DISORDERS; DENERVATION; HIPPOCAMPUS; MICE; MICE, TRANSGENIC; PRESENILIN-1; TIME FACTORS;

MLCS; MLOWN;

EID: 84877145078     PISSN: 00223069     EISSN: 15546578     Source Type: Journal    
DOI: 10.1097/NEN.0b013e318288a8dd     Document Type: Article

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