Inflammatory stress increases hepatic CD36 translational efficiency via activation of the mTOR signalling pathway

PLoS ONE

Volumn 9, Issue 7, 2014, Pages

  Wang, Chuan ^a   Hu, Lin ^a   Zhao, Lei ^a   Yang, Ping ^a   Moorhead, John F ^b   Varghese, Zac ^b   Chen, Yaxi ^a   Ruan, Xiong Z ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD36 ANTIGEN; FAT DROPLET; INITIATION FACTOR 4E; INITIATION FACTOR 4E BINDING PROTEIN 1; INTERLEUKIN 6; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; S6 KINASE; TUMOR NECROSIS FACTOR ALPHA; COMPLEMENT COMPONENT C3B RECEPTOR; TARGET OF RAPAMYCIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD36 GENE; CELL STRESS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FATTY LIVER; GENE; GENE EXPRESSION; HEPG2 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY STRESS; INTRACELLULAR SIGNALING; LIPID STORAGE; MALE; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN STABILITY; TRANSLATION INITIATION; TRANSLATION REGULATION; ANIMAL; DRUG EFFECTS; INFLAMMATION; LIVER; METABOLISM; NONALCOHOLIC FATTY LIVER; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION;

ANIMALS; HEP G2 CELLS; HUMANS; INFLAMMATION; INTERLEUKIN-6; LIVER; MALE; MICE; NON-ALCOHOLIC FATTY LIVER DISEASE; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; RECEPTORS, COMPLEMENT 3B; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84904678224     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0103071     Document Type: Article

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