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Volumn 33, Issue 5, 2013, Pages 227-238

The oncogene eIF4E: Using biochemical insights to target cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CAP BINDING PROTEIN; CYTARABINE; INITIATION FACTOR 4E; LY 2275796; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; RAS PROTEIN; RIBAVIRIN; UNCLASSIFIED DRUG;

EID: 84877843724     PISSN: 10799907     EISSN: 15577465     Source Type: Journal    
DOI: 10.1089/jir.2012.0142     Document Type: Review
Times cited : (87)

References (136)
  • 2
    • 0024361258 scopus 로고
    • A mammalian translation initiation factor can substitute for its yeast homologue in vivo
    • Altmann M, Muller PP, Pelletier J, Sonenberg N, Trachsel H. 1989. A mammalian translation initiation factor can substitute for its yeast homologue in vivo. J Biol Chem 264(21):12145-12147.
    • (1989) J Biol Chem , vol.264 , Issue.21 , pp. 12145-12147
    • Altmann, M.1    Muller, P.P.2    Pelletier, J.3    Sonenberg, N.4    Trachsel, H.5
  • 7
    • 0034904742 scopus 로고    scopus 로고
    • Expression of the translation initiation factor eIF4E in the polypcancer sequence in the colon
    • Berkel HJ, Turbat-Herrera EA, Shi R, de Benedetti A. 2001. Expression of the translation initiation factor eIF4E in the polypcancer sequence in the colon. Cancer Epidemiol Biomarkers Prev 10(6):663-666.
    • (2001) Cancer Epidemiol Biomarkers Prev , vol.10 , Issue.6 , pp. 663-666
    • Berkel, H.J.1    Turbat-Herrera, E.A.2    Shi, R.3    De Benedetti, A.4
  • 8
    • 0031436254 scopus 로고    scopus 로고
    • Disruption of the gene encoding the mitogen-regulated translational modulator PHAS-I in mice
    • Blackshear PJ, Stumpo DJ, Carballo E, Lawrence JC, Jr. 1997. Disruption of the gene encoding the mitogen-regulated translational modulator PHAS-I in mice. J Biol Chem 272(50): 31510-31514.
    • (1997) J Biol Chem , vol.272 , Issue.50 , pp. 31510-31514
    • Blackshear, P.J.1    Stumpo, D.J.2    Carballo, E.3    Lawrence Jr., J.C.4
  • 9
    • 79955637310 scopus 로고    scopus 로고
    • The biological and therapeutic relevance of mRNA translation in cancer
    • Blagden SP, Willis AE. 2011. The biological and therapeutic relevance of mRNA translation in cancer. Nat Rev Clin Oncol 8(5):280-291.
    • (2011) Nat Rev Clin Oncol , vol.8 , Issue.5 , pp. 280-291
    • Blagden, S.P.1    Willis, A.E.2
  • 10
    • 77957737145 scopus 로고    scopus 로고
    • Ribavirin as an anticancer therapy: Acute myeloid leukemia and beyond?
    • Borden KL, Culjkovic-Kraljacic B. 2010. Ribavirin as an anticancer therapy: Acute myeloid leukemia and beyond? Leuk Lymphoma 51(10):1805-1815.
    • (2010) Leuk Lymphoma , vol.51 , Issue.10 , pp. 1805-1815
    • Borden, K.L.1    Culjkovic-Kraljacic, B.2
  • 11
    • 67649302863 scopus 로고    scopus 로고
    • Crystallization of eIF4E complexed with eIF4GI peptide and glycerol reveals distinct structural differences around the capbinding site
    • Brown CJ, Verma CS, Walkinshaw MD, Lane DP. 2009. Crystallization of eIF4E complexed with eIF4GI peptide and glycerol reveals distinct structural differences around the capbinding site. Cell Cycle 8(12):1905-1911.
    • (2009) Cell Cycle , vol.8 , Issue.12 , pp. 1905-1911
    • Brown, C.J.1    Verma, C.S.2    Walkinshaw, M.D.3    Lane, D.P.4
  • 14
    • 0029831167 scopus 로고    scopus 로고
    • Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002
    • Brunn GJ, Williams J, Sabers C, Wiederrecht G, Lawrence JC, Jr., Abraham RT. 1996. Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002. EMBO J 15(19):5256-5267.
    • (1996) EMBO J , vol.15 , Issue.19 , pp. 5256-5267
    • Brunn, G.J.1    Williams, J.2    Sabers, C.3    Wiederrecht, G.4    Lawrence Jr., J.C.5    Abraham, R.T.6
  • 15
    • 0032535177 scopus 로고    scopus 로고
    • C-myc null cells misregulate cad and gadd45 but not other proposed c-Myc targets
    • Bush A, Mateyak M, Dugan K, Obaya A, Adachi S, Sedivy J, Cole M. 1998. c-myc null cells misregulate cad and gadd45 but not other proposed c-Myc targets. Genes Dev 12(24):3797-3802.
    • (1998) Genes Dev , vol.12 , Issue.24 , pp. 3797-3802
    • Bush, A.1    Mateyak, M.2    Dugan, K.3    Obaya, A.4    Adachi, S.5    Sedivy, J.6    Cole, M.7
  • 16
    • 0025904758 scopus 로고
    • A comparison of the binding of methylated cap analogues to wheat germ protein synthesis initiation factors 4F and (iso)4F
    • Carberry SE, Darzynkiewicz E, Goss DJ. 1991. A comparison of the binding of methylated cap analogues to wheat germ protein synthesis initiation factors 4F and (iso)4F. Biochemistry 30(6):1624-1627.
    • (1991) Biochemistry , vol.30 , Issue.6 , pp. 1624-1627
    • Carberry, S.E.1    Darzynkiewicz, E.2    Goss, D.J.3
  • 17
    • 0025305167 scopus 로고
    • A spectroscopic study of the binding of N-7-substituted cap analogues to human protein synthesis initiation factor 4E
    • Carberry SE, Darzynkiewicz E, Stepinski J, Tahara SM, Rhoads RE, Goss DJ. 1990. A spectroscopic study of the binding of N-7-substituted cap analogues to human protein synthesis initiation factor 4E. Biochemistry 29(13):3337-3341.
    • (1990) Biochemistry , vol.29 , Issue.13 , pp. 3337-3341
    • Carberry, S.E.1    Darzynkiewicz, E.2    Stepinski, J.3    Tahara, S.M.4    Rhoads, R.E.5    Goss, D.J.6
  • 18
    • 84868676397 scopus 로고    scopus 로고
    • Phosphorylation of the eukaryotic translation initiation factor 4E-transporter (4E-T) by c-Jun Nterminal kinase promotes stress-dependent P-body assembly
    • Cargnello M, Tcherkezian J, Dorn JF, Huttlin EL, Maddox PS, Gygi SP, Roux PP. 2012. Phosphorylation of the eukaryotic translation initiation factor 4E-transporter (4E-T) by c-Jun Nterminal kinase promotes stress-dependent P-body assembly. Mol Cell Biol 32(22):4572-4584.
    • (2012) Mol Cell Biol , vol.32 , Issue.22 , pp. 4572-4584
    • Cargnello, M.1    Tcherkezian, J.2    Dorn, J.F.3    Huttlin, E.L.4    Maddox, P.S.5    Gygi, S.P.6    Roux, P.P.7
  • 21
    • 0035881526 scopus 로고    scopus 로고
    • PML RING suppresses oncogenic transformation by reducing the affinity of eIF4E for mRNA
    • Cohen N, Sharma M, Kentsis A, Perez JM, Strudwick S, Borden KL. 2001. PML RING suppresses oncogenic transformation by reducing the affinity of eIF4E for mRNA. Embo J 20(16):4547-4559.
    • (2001) Embo J , vol.20 , Issue.16 , pp. 4547-4559
    • Cohen, N.1    Sharma, M.2    Kentsis, A.3    Perez, J.M.4    Strudwick, S.5    Borden, K.L.6
  • 22
    • 0033988498 scopus 로고    scopus 로고
    • Eukaryotic initiation factor-4E in superficial and muscle invasive bladder cancer and its correlation with vascular endothelial growth factor expression and tumour progression
    • Crew JP, Fuggle S, Bicknell R, Cranston DW, de Benedetti A, Harris AL. 2000. Eukaryotic initiation factor-4E in superficial and muscle invasive bladder cancer and its correlation with vascular endothelial growth factor expression and tumour progression. Br J Cancer 82(1):161-166.
    • (2000) Br J Cancer , vol.82 , Issue.1 , pp. 161-166
    • Crew, J.P.1    Fuggle, S.2    Bicknell, R.3    Cranston, D.W.4    De Benedetti, A.5    Harris, A.L.6
  • 23
    • 0030018742 scopus 로고    scopus 로고
    • Bladder cancer angiogenesis, its role in recurrence, stage progression and as a therapeutic target
    • Crew JP, O'Brien TS, Harris AL. 1996. Bladder cancer angiogenesis, its role in recurrence, stage progression and as a therapeutic target. Cancer Metastasis Rev 15(2):221-230.
    • (1996) Cancer Metastasis Rev , vol.15 , Issue.2 , pp. 221-230
    • Crew, J.P.1    O'Brien, T.S.2    Harris, A.L.3
  • 25
    • 73449136900 scopus 로고    scopus 로고
    • Understanding and targeting the eukaryotic translation initiation factor eIF4E in head and neck cancer
    • Culjkovic B, Borden KL. 2009. Understanding and targeting the eukaryotic translation initiation factor eIF4E in head and neck cancer. J Oncol 2009:981679.
    • (2009) J Oncol , vol.2009 , pp. 981679
    • Culjkovic, B.1    Borden, K.L.2
  • 27
    • 33846648989 scopus 로고    scopus 로고
    • Controlling gene expression through RNA regulons: The role of the eukaryotic translation initiation factor eIF4E
    • Culjkovic B, Topisirovic I, Borden KL. 2007. Controlling gene expression through RNA regulons: The role of the eukaryotic translation initiation factor eIF4E. Cell Cycle 6(1):65-69.
    • (2007) Cell Cycle , vol.6 , Issue.1 , pp. 65-69
    • Culjkovic, B.1    Topisirovic, I.2    Borden, K.L.3
  • 30
    • 84865803029 scopus 로고    scopus 로고
    • The oncogene eIF4E reprograms the nuclear pore complext to promote mRNA export and oncogenic transformation
    • Culjkovic-Kraljacic B, Baguet A, Volpon L, Amri A, Borden KLB. 2012. The oncogene eIF4E reprograms the nuclear pore complext to promote mRNA export and oncogenic transformation. Cell Rep 2(2):207-215.
    • (2012) Cell Rep , vol.2 , Issue.2 , pp. 207-215
    • Culjkovic-Kraljacic, B.1    Baguet, A.2    Volpon, L.3    Amri, A.4    Borden, K.L.B.5
  • 31
    • 0033044355 scopus 로고    scopus 로고
    • EIF4E expression in tumors: Its possible role in progression and malignacies
    • De Benedetti A, Harris AL. 1999. eIF4E expression in tumors: Its possible role in progression and malignacies. Int J Biochem Cell Biol 31:59-72.
    • (1999) Int J Biochem Cell Biol , vol.31 , pp. 59-72
    • De Benedetti, A.1    Harris, A.L.2
  • 32
    • 0025943409 scopus 로고
    • Expression of antisense RNA against initiation factor eIF-4E mRNA in HeLa cells results in lengthened cell division times, diminished translation rates, and reduced levels of both eIF-4E and the p220 component of eIF-4F
    • De Benedetti A, Joshi-Barve S, Rinker-Schaeffer C, Rhoads RE. 1991. Expression of antisense RNA against initiation factor eIF-4E mRNA in HeLa cells results in lengthened cell division times, diminished translation rates, and reduced levels of both eIF-4E and the p220 component of eIF-4F. Mol Cell Biol 11(11):5435-5445.
    • (1991) Mol Cell Biol , vol.11 , Issue.11 , pp. 5435-5445
    • De Benedetti, A.1    Joshi-Barve, S.2    Rinker-Schaeffer, C.3    Rhoads, R.E.4
  • 33
    • 0025107684 scopus 로고
    • Overexpression of eukaryotic protein synthesis initiation factor 4E in HeLa cells results in aberrant growth and morphology
    • De Benedetti A, Rhoads RE. 1990. Overexpression of eukaryotic protein synthesis initiation factor 4E in HeLa cells results in aberrant growth and morphology. Proc Natl Acad Sci U S A 87(21):8212-8216.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , Issue.21 , pp. 8212-8216
    • De Benedetti, A.1    Rhoads, R.E.2
  • 35
    • 0034707668 scopus 로고    scopus 로고
    • Nuclear eukaryotic initiation factor 4E (eIF4E) colocalizes with splicing factors in speckles
    • Dostie J, Lejbkowicz F, Sonenberg N. 2000. Nuclear eukaryotic initiation factor 4E (eIF4E) colocalizes with splicing factors in speckles. J Cell Biol 148(2):239-247.
    • (2000) J Cell Biol , vol.148 , Issue.2 , pp. 239-247
    • Dostie, J.1    Lejbkowicz, F.2    Sonenberg, N.3
  • 38
    • 84855379287 scopus 로고    scopus 로고
    • Yeast mRNA cap-binding protein Cbc1/Sto1 is necessary for the rapid reprogramming of translation after hyperosmotic shock
    • Garre E, Romero-Santacreu L, De Clercq N, Blasco-Angulo N, Sunnerhagen P, Alepuz P. 2011. Yeast mRNA cap-binding protein Cbc1/Sto1 is necessary for the rapid reprogramming of translation after hyperosmotic shock. Mol Biol Cell 23(1): 137-150.
    • (2011) Mol Biol Cell , vol.23 , Issue.1 , pp. 137-150
    • Garre, E.1    Romero-Santacreu, L.2    De Clercq, N.3    Blasco-Angulo, N.4    Sunnerhagen, P.5    Alepuz, P.6
  • 40
    • 0032520009 scopus 로고    scopus 로고
    • 4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway
    • Gingras AC, Kennedy SG, O'Leary MA, Sonenberg N, Hay N. 1998. 4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway. Genes Dev 12(4):502-513.
    • (1998) Genes Dev , vol.12 , Issue.4 , pp. 502-513
    • Gingras, A.C.1    Kennedy, S.G.2    O'Leary, M.A.3    Sonenberg, N.4    Hay, N.5
  • 41
    • 0032949443 scopus 로고    scopus 로고
    • The clinical pharmacology of ribavirin
    • Glue P. 1999. The clinical pharmacology of ribavirin. Semin Liver Dis 19 Suppl 1:17-24.
    • (1999) Semin Liver Dis , vol.19 , Issue.SUPPL. 1 , pp. 17-24
    • Glue, P.1
  • 42
    • 0031558804 scopus 로고    scopus 로고
    • Translation of ODC mRNA and polyamine transport are suppressed in ras-transformed CREF cells by depleting translation initiation factor 4E
    • Graff JR, De Benedetti A, Olson JW, Tamez P, Casero RA, Jr., Zimmer SG. 1997. Translation of ODC mRNA and polyamine transport are suppressed in ras-transformed CREF cells by depleting translation initiation factor 4E. Biochem Biophys Res Commun 240(1):15-20.
    • (1997) Biochem Biophys Res Commun , vol.240 , Issue.1 , pp. 15-20
    • Graff, J.R.1    De Benedetti, A.2    Olson, J.W.3    Tamez, P.4    Casero Jr., R.A.5    Zimmer, S.G.6
  • 44
    • 1842816418 scopus 로고    scopus 로고
    • Insights into the structure, mechanism, and regulation of scavenger mRNA decapping activity
    • Gu M, Fabrega C, Liu SW, Liu H, Kiledjian M, Lima CD. 2004. Insights into the structure, mechanism, and regulation of scavenger mRNA decapping activity. Mol Cell 14(1):67-80.
    • (2004) Mol Cell , vol.14 , Issue.1 , pp. 67-80
    • Gu, M.1    Fabrega, C.2    Liu, S.W.3    Liu, H.4    Kiledjian, M.5    Lima, C.D.6
  • 45
    • 0028786952 scopus 로고
    • Repression of cap-dependent translation by 4E-binding protein 1: Competition with p220 for binding to eukaryotic initiation factor-4E
    • Haghighat A, Mader S, Pause A, Sonenberg N. 1995. Repression of cap-dependent translation by 4E-binding protein 1: Competition with p220 for binding to eukaryotic initiation factor-4E. EMBO J 14(22):5701-5709.
    • (1995) EMBO J , vol.14 , Issue.22 , pp. 5701-5709
    • Haghighat, A.1    Mader, S.2    Pause, A.3    Sonenberg, N.4
  • 47
    • 0036389861 scopus 로고    scopus 로고
    • Pleiotropic mechanisms of ribavirin antiviral activities
    • Hong Z, Cameron CE. 2002. Pleiotropic mechanisms of ribavirin antiviral activities. Prog Drug Res 59:41-69.
    • (2002) Prog Drug Res , vol.59 , pp. 41-69
    • Hong, Z.1    Cameron, C.E.2
  • 48
    • 0031442452 scopus 로고    scopus 로고
    • Pim-1 protein expression is regulated by its 5¢-untranslated region and translation initiation factor elF-4E
    • Hoover DS, Wingett DG, Zhang J, Reeves R, Magnuson NS. 1997. Pim-1 protein expression is regulated by its 5¢-untranslated region and translation initiation factor elF-4E. Cell Growth Differ 8(12):1371-1380.
    • (1997) Cell Growth Differ , vol.8 , Issue.12 , pp. 1371-1380
    • Hoover, D.S.1    Wingett, D.G.2    Zhang, J.3    Reeves, R.4    Magnuson, N.S.5
  • 49
    • 0035839002 scopus 로고    scopus 로고
    • Coupled transcription and translation within nuclei of mammalian cells
    • Iborra FJ, Jackson DA, Cook PR. 2001. Coupled transcription and translation within nuclei of mammalian cells. Science 293(5532):1139-1142.
    • (2001) Science , vol.293 , Issue.5532 , pp. 1139-1142
    • Iborra, F.J.1    Jackson, D.A.2    Cook, P.R.3
  • 51
    • 79953214948 scopus 로고    scopus 로고
    • Essential role for Mnk kinases in type II interferon (IFNgamma) signaling and its suppressive effects on normal hematopoiesis
    • Joshi S, Sharma B, Kaur S, Majchrzak B, Ueda T, Fukunaga R, Verma AK, Fish EN, Platanias LC. 2011. Essential role for Mnk kinases in type II interferon (IFNgamma) signaling and its suppressive effects on normal hematopoiesis. J Biol Chem 286(8):6017-6026.
    • (2011) J Biol Chem , vol.286 , Issue.8 , pp. 6017-6026
    • Joshi, S.1    Sharma, B.2    Kaur, S.3    Majchrzak, B.4    Ueda, T.5    Fukunaga, R.6    Verma, A.K.7    Fish, E.N.8    Platanias, L.C.9
  • 52
    • 0027300051 scopus 로고
    • Characterization of wild-type and Ser53 mutant eukaryotic initiation factor 4E overexpression in mammalian cells
    • Kaufman RJ, Murtha-Riel P, Pittman DD, Davies MV. 1993. Characterization of wild-type and Ser53 mutant eukaryotic initiation factor 4E overexpression in mammalian cells. J Biol Chem 268(16):11902-11909.
    • (1993) J Biol Chem , vol.268 , Issue.16 , pp. 11902-11909
    • Kaufman, R.J.1    Murtha-Riel, P.2    Pittman, D.D.3    Davies, M.V.4
  • 53
    • 34250735674 scopus 로고    scopus 로고
    • RNA regulons: Coordination of post-transcriptional events
    • Keene JD. 2007. RNA regulons: Coordination of post-transcriptional events. Nat Rev Genet 8(7):533-543.
    • (2007) Nat Rev Genet , vol.8 , Issue.7 , pp. 533-543
    • Keene, J.D.1
  • 54
    • 23444446940 scopus 로고    scopus 로고
    • Post-transcriptional operons and regulons co-ordinating gene expression
    • Keene JD, Lager PJ. 2005. Post-transcriptional operons and regulons co-ordinating gene expression. Chromosome Res 13(3):327-337.
    • (2005) Chromosome Res , vol.13 , Issue.3 , pp. 327-337
    • Keene, J.D.1    Lager, P.J.2
  • 55
    • 0036289532 scopus 로고    scopus 로고
    • Eukaryotic mRNPs may represent posttranscriptional operons
    • Keene JD, Tenenbaum SA. 2002. Eukaryotic mRNPs may represent posttranscriptional operons. Mol Cell 9(6):1161-1167.
    • (2002) Mol Cell , vol.9 , Issue.6 , pp. 1161-1167
    • Keene, J.D.1    Tenenbaum, S.A.2
  • 56
    • 0035965139 scopus 로고    scopus 로고
    • The RING domains of the promyelocytic leukemia protein PML and the arenaviral protein Z repress translation by directly inhibiting translation initiation factor eIF4E
    • Kentsis A, Dwyer EC, Perez JM, Sharma M, Chen A, Pan ZQ, Borden KL. 2001. The RING domains of the promyelocytic leukemia protein PML and the arenaviral protein Z repress translation by directly inhibiting translation initiation factor eIF4E. J Mol Biol 312(4):609-623.
    • (2001) J Mol Biol , vol.312 , Issue.4 , pp. 609-623
    • Kentsis, A.1    Dwyer, E.C.2    Perez, J.M.3    Sharma, M.4    Chen, A.5    Pan, Z.Q.6    Borden, K.L.7
  • 57
    • 0037180485 scopus 로고    scopus 로고
    • Control of biochemical reactions through supramolecular RING domain self-assembly
    • Kentsis A, Gordon RE, Borden KL. 2002a. Control of biochemical reactions through supramolecular RING domain self-assembly. Proc Natl Acad Sci U S A 99(24):15404-15409.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , Issue.24 , pp. 15404-15409
    • Kentsis, A.1    Gordon, R.E.2    Borden, K.L.3
  • 59
    • 11144220618 scopus 로고    scopus 로고
    • Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap
    • Kentsis A, Topisirovic I, Culjkovic B, Shao L, Borden KL. 2004. Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap. Proc Natl Acad Sci U S A 101(52):18105-18110.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.52 , pp. 18105-18110
    • Kentsis, A.1    Topisirovic, I.2    Culjkovic, B.3    Shao, L.4    Borden, K.L.5
  • 61
    • 84866544803 scopus 로고    scopus 로고
    • Up-regulation of translation eukaryotic initiation factor 4E in nucleophosmin 1 haploinsufficient cells results in changes in CCAAT enhancer-binding protein alpha activity: Implications in myelodysplastic syndrome and acute myeloid leukemia
    • Khanna-Gupta A, Abayasekara N, Levine M, Sun H, Virgilio M, Nia N, Halene S, Sportoletti P, Jeong JY, Pandolfi PP, Berliner N. 2012. Up-regulation of translation eukaryotic initiation factor 4E in nucleophosmin 1 haploinsufficient cells results in changes in CCAAT enhancer-binding protein alpha activity: Implications in myelodysplastic syndrome and acute myeloid leukemia. J Biol Chem 287(39):32728-32737.
    • (2012) J Biol Chem , vol.287 , Issue.39 , pp. 32728-32737
    • Khanna-Gupta, A.1    Abayasekara, N.2    Levine, M.3    Sun, H.4    Virgilio, M.5    Nia, N.6    Halene, S.7    Sportoletti, P.8    Jeong, J.Y.9    Pandolfi, P.P.10    Berliner, N.11
  • 62
    • 84865118901 scopus 로고    scopus 로고
    • Crystal structure of a minimal eIF4E-Cup complex reveals a general mechanism of eIF4E regulation in translational repression
    • Kinkelin K, Veith K, Grunwald M, Bono F. 2012. Crystal structure of a minimal eIF4E-Cup complex reveals a general mechanism of eIF4E regulation in translational repression. RNA 18(9):1624-1634.
    • (2012) RNA , vol.18 , Issue.9 , pp. 1624-1634
    • Kinkelin, K.1    Veith, K.2    Grunwald, M.3    Bono, F.4
  • 63
    • 0034928792 scopus 로고    scopus 로고
    • Negative regulation of protein translation by mitogen-activated protein kinaseinteracting kinases 1 and 2
    • Knauf U, Tschopp C, Gram H. 2001. Negative regulation of protein translation by mitogen-activated protein kinaseinteracting kinases 1 and 2. Mol Cell Biol 21(16):5500-5511.
    • (2001) Mol Cell Biol , vol.21 , Issue.16 , pp. 5500-5511
    • Knauf, U.1    Tschopp, C.2    Gram, H.3
  • 64
    • 67650366798 scopus 로고    scopus 로고
    • Inhibition of ovarian cancer growth by a tumor-targeting peptide that binds eukaryotic translation initiation factor 4E
    • Ko SY, Guo H, Barengo N, Naora H. 2009. Inhibition of ovarian cancer growth by a tumor-targeting peptide that binds eukaryotic translation initiation factor 4E. Clin Cancer Res 15(13):4336-4347.
    • (2009) Clin Cancer Res , vol.15 , Issue.13 , pp. 4336-4347
    • Ko, S.Y.1    Guo, H.2    Barengo, N.3    Naora, H.4
  • 66
    • 79960245689 scopus 로고    scopus 로고
    • Inhibition of eIF4E with ribavirin cooperates with common chemotherapies in primary acute myeloid leukemia specimens
    • Kraljacic BC, Arguello M, Amri A, Cormack G, Borden K. 2011. Inhibition of eIF4E with ribavirin cooperates with common chemotherapies in primary acute myeloid leukemia specimens. Leukemia 25(7):1197-1200.
    • (2011) Leukemia , vol.25 , Issue.7 , pp. 1197-1200
    • Kraljacic, B.C.1    Arguello, M.2    Amri, A.3    Cormack, G.4    Borden, K.5
  • 67
    • 0025314596 scopus 로고
    • Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5¢ cap
    • Lazaris-Karatzas A, Montine KS, Sonenberg N. 1990. Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5¢ cap. Nature 345(6275):544-547.
    • (1990) Nature , vol.345 , Issue.6275 , pp. 544-547
    • Lazaris-Karatzas, A.1    Montine, K.S.2    Sonenberg, N.3
  • 70
    • 0026705268 scopus 로고
    • A fraction of the mRNA 5¢ cap-binding protein, eukaryotic initiation factor 4E, localizes to the nucleus
    • Lejbkowicz F, Goyer C, Darveau A, Neron S, Lemieux R, Sonenberg N. 1992. A fraction of the mRNA 5¢ cap-binding protein, eukaryotic initiation factor 4E, localizes to the nucleus. Proc Natl Acad Sci U S A 89(20):9612-9616.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , Issue.20 , pp. 9612-9616
    • Lejbkowicz, F.1    Goyer, C.2    Darveau, A.3    Neron, S.4    Lemieux, R.5    Sonenberg, N.6
  • 71
    • 0036236341 scopus 로고    scopus 로고
    • Prospective study of eukaryotic initiation factor 4E protein elevation and breast cancer outcome
    • 732-738 discussion
    • Li BD, Gruner JS, Abreo F, Johnson LW, Yu H, Nawas S, McDonald JC, DeBenedetti A. 2002. Prospective study of eukaryotic initiation factor 4E protein elevation and breast cancer outcome. Ann Surg 235(5):732-738; discussion 738-739.
    • (2002) Ann Surg , vol.235 , Issue.5 , pp. 738-739
    • Li, B.D.1    Gruner, J.S.2    Abreo, F.3    Johnson, L.W.4    Yu, H.5    Nawas, S.6    McDonald, J.C.7    DeBenedetti, A.8
  • 74
    • 22544464680 scopus 로고    scopus 로고
    • HnRNP K binds a core polypyrimidine element in the eukaryotic translation initiation factor 4E (eIF4E) promoter, and its regulation of eIF4E contributes to neoplastic transformation
    • Lynch M, Chen L, Ravitz MJ, Mehtani S, Korenblat K, Pazin MJ, Schmidt EV. 2005. hnRNP K binds a core polypyrimidine element in the eukaryotic translation initiation factor 4E (eIF4E) promoter, and its regulation of eIF4E contributes to neoplastic transformation. Mol Cell Biol 25(15):6436-6453.
    • (2005) Mol Cell Biol , vol.25 , Issue.15 , pp. 6436-6453
    • Lynch, M.1    Chen, L.2    Ravitz, M.J.3    Mehtani, S.4    Korenblat, K.5    Pazin, M.J.6    Schmidt, E.V.7
  • 75
    • 0029166687 scopus 로고
    • The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the translational repressors 4E-binding proteins
    • Mader S, Lee H, Pause A, Sonenberg N. 1995. The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the translational repressors 4E-binding proteins. Mol Cell Biol 15(9):4990-4997.
    • (1995) Mol Cell Biol , vol.15 , Issue.9 , pp. 4990-4997
    • Mader, S.1    Lee, H.2    Pause, A.3    Sonenberg, N.4
  • 76
    • 79954622470 scopus 로고    scopus 로고
    • Divergent functions for eIF4E and S6 kinase by sonic hedgehog mitogenic signaling in the developing cerebellum
    • Mainwaring LA, Kenney AM. 2011. Divergent functions for eIF4E and S6 kinase by sonic hedgehog mitogenic signaling in the developing cerebellum. Oncogene 30(15):1784-1797.
    • (2011) Oncogene , vol.30 , Issue.15 , pp. 1784-1797
    • Mainwaring, L.A.1    Kenney, A.M.2
  • 77
    • 77955326776 scopus 로고    scopus 로고
    • The pioneer round of translation: Features and functions
    • Maquat LE, Tarn WY, Isken O. 2010. The pioneer round of translation: Features and functions. Cell 142(3):368-374.
    • (2010) Cell , vol.142 , Issue.3 , pp. 368-374
    • Maquat, L.E.1    Tarn, W.Y.2    Isken, O.3
  • 78
    • 0030728936 scopus 로고    scopus 로고
    • Cocrystal structure of the messenger RNA 5¢ cap-binding protein (eIF4E) bound to 7-methyl-GDP
    • Marcotrigiano J, Gingras AC, Sonenberg N, Burley SK. 1997. Cocrystal structure of the messenger RNA 5¢ cap-binding protein (eIF4E) bound to 7-methyl-GDP. Cell 89(6):951-961.
    • (1997) Cell , vol.89 , Issue.6 , pp. 951-961
    • Marcotrigiano, J.1    Gingras, A.C.2    Sonenberg, N.3    Burley, S.K.4
  • 79
    • 0033152072 scopus 로고    scopus 로고
    • Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G
    • Marcotrigiano J, Gingras AC, Sonenberg N, Burley SK. 1999. Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G. Mol Cell 3(6):707-716.
    • (1999) Mol Cell , vol.3 , Issue.6 , pp. 707-716
    • Marcotrigiano, J.1    Gingras, A.C.2    Sonenberg, N.3    Burley, S.K.4
  • 81
    • 80052828293 scopus 로고    scopus 로고
    • Simultaneous inhibition of mTOR-containing complex 1 (mTORC1) and MNK induces apoptosis of cutaneous T-cell lymphoma (CTCL) cells
    • Marzec M, Liu X, Wysocka M, Rook AH, Odum N, Wasik MA. 2011. Simultaneous inhibition of mTOR-containing complex 1 (mTORC1) and MNK induces apoptosis of cutaneous T-cell lymphoma (CTCL) cells. PLoS One 6(9):e24849.
    • (2011) PLoS One , vol.6 , Issue.9
    • Marzec, M.1    Liu, X.2    Wysocka, M.3    Rook, A.H.4    Odum, N.5    Wasik, M.A.6
  • 84
    • 0030013326 scopus 로고    scopus 로고
    • Stimulation of protein syn thesis, Eukaryotic translation initiation factor 4E phosphorylation, and PHAS-I phosphorylation by insulin requires insulin receptor substrate 1 and phosphatidylinositol 3-kinase
    • Mendez R, Myers MG, Jr., White MF, Rhoads RE. 1996. Stimulation of protein synthesis, eukaryotic translation initiation factor 4E phosphorylation, and PHAS-I phosphorylation by insulin requires insulin receptor substrate 1 and phosphatidylinositol 3-kinase. Mol Cell Biol 16(6):2857-2864.
    • (1996) Mol Cell Biol , vol.16 , Issue.6 , pp. 2857-2864
    • Mendez, R.1    Myers Jr., M.G.2    White, M.F.3    Rhoads, R.E.4
  • 85
    • 33644753088 scopus 로고    scopus 로고
    • The potyviral virus genome-linked protein VPg forms a ternary complex with the eukaryotic initiation factors eIF4E and eIF4G and reduces eIF4E affinity for a mRNA cap analogue
    • Michon T, Estevez Y, Walter J, German-Retana S, Le Gall O. 2006. The potyviral virus genome-linked protein VPg forms a ternary complex with the eukaryotic initiation factors eIF4E and eIF4G and reduces eIF4E affinity for a mRNA cap analogue. FEBS J 273(6):1312-1322.
    • (2006) FEBS J , vol.273 , Issue.6 , pp. 1312-1322
    • Michon, T.1    Estevez, Y.2    Walter, J.3    German-Retana, S.4    Le Gall, O.5
  • 88
    • 0030808698 scopus 로고    scopus 로고
    • Detection of the proto-oncogene eIF4E in surgical margins may predict recurrence in head and neck cancer
    • Nathan CA, Liu L, Li BD, Abreo FW, Nandy I, De Benedetti A. 1997b. Detection of the proto-oncogene eIF4E in surgical margins may predict recurrence in head and neck cancer. Oncogene 15(5):579-584.
    • (1997) Oncogene , vol.15 , Issue.5 , pp. 579-584
    • Nathan, C.A.1    Liu, L.2    Li, B.D.3    Abreo, F.W.4    Nandy, I.5    De Benedetti, A.6
  • 89
    • 3242704789 scopus 로고    scopus 로고
    • Emx2 homeodomain transcription factor interacts with eukaryotic translation initiation factor 4E (eIF4E) in the axons of olfactory sensory neurons
    • Nedelec S, Foucher I, Brunet I, Bouillot C, Prochiantz A, Trembleau A. 2004. Emx2 homeodomain transcription factor interacts with eukaryotic translation initiation factor 4E (eIF4E) in the axons of olfactory sensory neurons. Proc Natl Acad Sci U S A 101(29):10815-10820.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.29 , pp. 10815-10820
    • Nedelec, S.1    Foucher, I.2    Brunet, I.3    Bouillot, C.4    Prochiantz, A.5    Trembleau, A.6
  • 90
    • 0036790664 scopus 로고    scopus 로고
    • Bicoid associates with the 5¢-cap-bound complex of caudal mRNA and represses translation
    • Niessing D, Blanke S, Jackle H. 2002. Bicoid associates with the 5¢-cap-bound complex of caudal mRNA and represses translation. Genes Dev 16(19):2576-2582.
    • (2002) Genes Dev , vol.16 , Issue.19 , pp. 2576-2582
    • Niessing, D.1    Blanke, S.2    Jackle, H.3
  • 92
    • 33847417585 scopus 로고    scopus 로고
    • P bodies and the control of mRNA translation and degradation
    • Parker R, Sheth U. 2007. P bodies and the control of mRNA translation and degradation. Mol Cell 25(5):635-646.
    • (2007) Mol Cell , vol.25 , Issue.5 , pp. 635-646
    • Parker, R.1    Sheth, U.2
  • 93
    • 84858228734 scopus 로고    scopus 로고
    • Single-cell pharmacodynamic monitoring of S6 ribosomal protein phosphorylation in AML blasts during a clinical trial combining the mTOR inhibitor sirolimus and intensive chemotherapy
    • Perl AE, Kasner MT, Shank D, Luger SM, Carroll M. 2012. Single-cell pharmacodynamic monitoring of S6 ribosomal protein phosphorylation in AML blasts during a clinical trial combining the mTOR inhibitor sirolimus and intensive chemotherapy. Clin Cancer Res 18(6):1716-1725.
    • (2012) Clin Cancer Res , vol.18 , Issue.6 , pp. 1716-1725
    • Perl, A.E.1    Kasner, M.T.2    Shank, D.3    Luger, S.M.4    Carroll, M.5
  • 96
    • 0029827631 scopus 로고    scopus 로고
    • Translational control of programmed cell death: Eukaryotic translation initiation factor 4E blocks apoptosis in growth-factor-restricted fibroblasts with physiologically expressed or deregulated Myc
    • Polunovsky VA, Rosenwald IB, Tan AT, White J, Chiang L, Sonenberg N, Bitterman PB. 1996. Translational control of programmed cell death: Eukaryotic translation initiation factor 4E blocks apoptosis in growth-factor-restricted fibroblasts with physiologically expressed or deregulated Myc. Mol Cell Biol 16(11):6573-6581.
    • (1996) Mol Cell Biol , vol.16 , Issue.11 , pp. 6573-6581
    • Polunovsky, V.A.1    Rosenwald, I.B.2    Tan, A.T.3    White, J.4    Chiang, L.5    Sonenberg, N.6    Bitterman, P.B.7
  • 97
    • 0033565233 scopus 로고    scopus 로고
    • Repressor binding to a dorsal regulatory site traps human eIF4E in a high cap-affinity state
    • Ptushkina M, von der Haar T, Karim MM, Hughes JM, McCarthy JE. 1999. Repressor binding to a dorsal regulatory site traps human eIF4E in a high cap-affinity state. Embo J 18(14):4068-4075.
    • (1999) Embo J , vol.18 , Issue.14 , pp. 4068-4075
    • Ptushkina, M.1    Von Der Haar, T.2    Karim, M.M.3    Hughes, J.M.4    McCarthy, J.E.5
  • 98
    • 0032541425 scopus 로고    scopus 로고
    • Cooperative modulation by eIF4G of eIF4E-binding to the mRNA 5¢ cap in yeast involves a site partially shared by p20
    • Ptushkina M, von der Haar T, Vasilescu S, Frank R, Birkenhager R, McCarthy JE. 1998. Cooperative modulation by eIF4G of eIF4E-binding to the mRNA 5¢ cap in yeast involves a site partially shared by p20. Embo J 17(16):4798-4808.
    • (1998) Embo J , vol.17 , Issue.16 , pp. 4798-4808
    • Ptushkina, M.1    Von Der Haar, T.2    Vasilescu, S.3    Frank, R.4    Birkenhager, R.5    McCarthy, J.E.6
  • 99
    • 0033975417 scopus 로고    scopus 로고
    • Structural basis of mRNA cap recognition by proteins
    • Quiocho FA, Hu G, Gershon PD. 2000. Structural basis of mRNA cap recognition by proteins. Curr Opin Struct Biol 10(1):78-86.
    • (2000) Curr Opin Struct Biol , vol.10 , Issue.1 , pp. 78-86
    • Quiocho, F.A.1    Hu, G.2    Gershon, P.D.3
  • 100
    • 67650543838 scopus 로고    scopus 로고
    • EIF4E: New family members, new binding partners, new roles
    • Rhoads RE. 2009. eIF4E: New family members, new binding partners, new roles. J Biol Chem 284(25):16711-16715.
    • (2009) J Biol Chem , vol.284 , Issue.25 , pp. 16711-16715
    • Rhoads, R.E.1
  • 101
    • 0027362742 scopus 로고
    • Decreasing the level of translation initiation factor 4E with antisense RNA causes reversal of ras-mediated transformation and tumorigenesis of cloned rat embryo fibroblasts
    • Rinker-Schaeffer CW, Graff JR, De Benedetti A, Zimmer SG, Rhoads RE. 1993. Decreasing the level of translation initiation factor 4E with antisense RNA causes reversal of ras-mediated transformation and tumorigenesis of cloned rat embryo fibroblasts. Int J Cancer 55(5):841-847.
    • (1993) Int J Cancer , vol.55 , Issue.5 , pp. 841-847
    • Rinker-Schaeffer, C.W.1    Graff, J.R.2    De Benedetti, A.3    Zimmer, S.G.4    Rhoads, R.E.5
  • 103
    • 33847630099 scopus 로고    scopus 로고
    • Central domain of a potyvirus VPg is involved in the interaction with the host translation initiation factor eIF4E and the viral protein HcPro
    • Roudet-Tavert G, Michon T, Walter J, Delaunay T, Redondo E, Le Gall O. 2007. Central domain of a potyvirus VPg is involved in the interaction with the host translation initiation factor eIF4E and the viral protein HcPro. J Gen Virol 88(Pt 3):1029-1033.
    • (2007) J Gen Virol , vol.88 , Issue.PART 3 , pp. 1029-1033
    • Roudet-Tavert, G.1    Michon, T.2    Walter, J.3    Delaunay, T.4    Redondo, E.5    Le Gall, O.6
  • 104
    • 0030041884 scopus 로고    scopus 로고
    • Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E
    • Rousseau D, Kaspar R, Rosenwald I, Gehrke L, Sonenberg N. 1996. Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E. Proc Natl Acad Sci U S A 93(3):1065-1070.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , Issue.3 , pp. 1065-1070
    • Rousseau, D.1    Kaspar, R.2    Rosenwald, I.3    Gehrke, L.4    Sonenberg, N.5
  • 105
    • 33646089881 scopus 로고    scopus 로고
    • Expression of the eukaryotic translation initiation factor 4E (eIF4E) and 4E-BP1 in esophageal cancer
    • Salehi Z, Mashayekhi F. 2006. Expression of the eukaryotic translation initiation factor 4E (eIF4E) and 4E-BP1 in esophageal cancer. Clin Biochem 39(4):404-409.
    • (2006) Clin Biochem , vol.39 , Issue.4 , pp. 404-409
    • Salehi, Z.1    Mashayekhi, F.2
  • 106
    • 0036438924 scopus 로고    scopus 로고
    • Does phosphorylation of the capbinding protein eIF4E play a role in translation initiation?
    • Scheper GC, Proud CG. 2002. Does phosphorylation of the capbinding protein eIF4E play a role in translation initiation? Eur J Biochem 269(22):5350-5359.
    • (2002) Eur J Biochem , vol.269 , Issue.22 , pp. 5350-5359
    • Scheper, G.C.1    Proud, C.G.2
  • 107
    • 2342645571 scopus 로고    scopus 로고
    • The role of c-myc in regulation of translation initiation
    • Schmidt EV. 2004. The role of c-myc in regulation of translation initiation. Oncogene 23(18):3217-3221.
    • (2004) Oncogene , vol.23 , Issue.18 , pp. 3217-3221
    • Schmidt, E.V.1
  • 108
    • 0036796009 scopus 로고    scopus 로고
    • Expression of eukaryotic initiation factor 4E in atypical adenomatous hyperplasia and adenocarcinoma of the human peripheral lung
    • Seki N, Takasu T, Mandai K, Nakata M, Saeki H, Heike Y, Takata I, Segawa Y, Hanafusa T, Eguchi K. 2002. Expression of eukaryotic initiation factor 4E in atypical adenomatous hyperplasia and adenocarcinoma of the human peripheral lung. Clin Cancer Res 8(10):3046-3053.
    • (2002) Clin Cancer Res , vol.8 , Issue.10 , pp. 3046-3053
    • Seki, N.1    Takasu, T.2    Mandai, K.3    Nakata, M.4    Saeki, H.5    Heike, Y.6    Takata, I.7    Segawa, Y.8    Hanafusa, T.9    Eguchi, K.10
  • 109
    • 38549101945 scopus 로고    scopus 로고
    • Candidate tumor suppressor DDX3 RNA helicase specifically represses capdependent translation by acting as an eIF4E inhibitory protein
    • Shih JW, Tsai TY, Chao CH, Wu Lee YH. 2008. Candidate tumor suppressor DDX3 RNA helicase specifically represses capdependent translation by acting as an eIF4E inhibitory protein. Oncogene 27(5):700-714.
    • (2008) Oncogene , vol.27 , Issue.5 , pp. 700-714
    • Shih, J.W.1    Tsai, T.Y.2    Chao, C.H.3    Wu Lee, Y.H.4
  • 110
    • 84055178425 scopus 로고    scopus 로고
    • Critical roles of RNA helicase DDX3 and its interactions with eIF4E/PABP1 in stress granule assembly and stress response
    • Shih JW, Wang WT, Tsai TY, Kuo CY, Li HK, Wu Lee YH. 2011 Critical roles of RNA helicase DDX3 and its interactions with eIF4E/PABP1 in stress granule assembly and stress response. Biochem J 441(1):119-129.
    • (2011) Biochem J , vol.441 , Issue.1 , pp. 119-129
    • Shih, J.W.1    Wang, W.T.2    Tsai, T.Y.3    Kuo, C.Y.4    Li, H.K.5    Wu Lee, Y.H.6
  • 111
    • 0032054816 scopus 로고    scopus 로고
    • The mRNA 5¢ cap-binding protein eIF4E and control of cell growth
    • Sonenberg N, Gingras AC. 1998. The mRNA 5¢ cap-binding protein eIF4E and control of cell growth. Curr Opin Cell Biol 10(2):268-275.
    • (1998) Curr Opin Cell Biol , vol.10 , Issue.2 , pp. 268-275
    • Sonenberg, N.1    Gingras, A.C.2
  • 114
    • 78049268257 scopus 로고    scopus 로고
    • Local control of a disorder-order transition in 4E-BP1 underpins regulation of translation via eIF4E
    • Tait S, Dutta K, Cowburn D, Warwicker J, Doig AJ, McCarthy JE. 2010. Local control of a disorder-order transition in 4E-BP1 underpins regulation of translation via eIF4E. Proc Natl Acad Sci U S A 107(41):17627-17632.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.41 , pp. 17627-17632
    • Tait, S.1    Dutta, K.2    Cowburn, D.3    Warwicker, J.4    Doig, A.J.5    McCarthy, J.E.6
  • 116
    • 0034624746 scopus 로고    scopus 로고
    • Inhibition of Myc-dependent apoptosis by eukaryotic translation initiation factor 4E requires cyclin D1
    • Tan A, Bitterman P, Sonenberg N, Peterson M, Polunovsky V. 2000. Inhibition of Myc-dependent apoptosis by eukaryotic translation initiation factor 4E requires cyclin D1. Oncogene 19(11):1437-1447.
    • (2000) Oncogene , vol.19 , Issue.11 , pp. 1437-1447
    • Tan, A.1    Bitterman, P.2    Sonenberg, N.3    Peterson, M.4    Polunovsky, V.5
  • 118
    • 0242541653 scopus 로고    scopus 로고
    • Human homologue of ariadne promotes the ubiquitylation of translation initiation factor 4E homologous protein, 4EHP
    • Tan NG, Ardley HC, Scott GB, Rose SA, Markham AF, Robinson PA. 2003. Human homologue of ariadne promotes the ubiquitylation of translation initiation factor 4E homologous protein, 4EHP. FEBS Lett 554(3):501-504.
    • (2003) FEBS Lett , vol.554 , Issue.3 , pp. 501-504
    • Tan, N.G.1    Ardley, H.C.2    Scott, G.B.3    Rose, S.A.4    Markham, A.F.5    Robinson, P.A.6
  • 119
    • 18744392514 scopus 로고    scopus 로고
    • RNA synthesis in a cage - structural studies of reovirus polymerase lambda3
    • Tao Y, Farsetta DL, Nibert ML, Harrison SC. 2002. RNA synthesis in a cage - structural studies of reovirus polymerase lambda3. Cell 111(5):733-745.
    • (2002) Cell , vol.111 , Issue.5 , pp. 733-745
    • Tao, Y.1    Farsetta, D.L.2    Nibert, M.L.3    Harrison, S.C.4
  • 120
    • 0034687794 scopus 로고    scopus 로고
    • Identifying mRNA subsets in messenger ribonucleoprotein complexes by using cDNA arrays
    • Tenenbaum SA, Carson CC, Lager PJ, Keene JD. 2000. Identifying mRNA subsets in messenger ribonucleoprotein complexes by using cDNA arrays. Proc Natl Acad Sci U S A 97(26):14085-14090.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , Issue.26 , pp. 14085-14090
    • Tenenbaum, S.A.1    Carson, C.C.2    Lager, P.J.3    Keene, J.D.4
  • 121
    • 27844576586 scopus 로고    scopus 로고
    • Structural basis for mRNA cap-binding regulation of eukaryotic initiation factor 4E by 4E-binding protein, studied by spectroscopic, X-ray crystal structural, and molecular dynamics simulation methods
    • Tomoo K, Matsushita Y, Fujisaki H, Abiko F, Shen X, Taniguchi T, Miyagawa H, Kitamura K, Miura K, Ishida T. 2005. Structural basis for mRNA cap-binding regulation of eukaryotic initiation factor 4E by 4E-binding protein, studied by spectroscopic, X-ray crystal structural, and molecular dynamics simulation methods. Biochim Biophys Acta 1753(2):191-208.
    • (2005) Biochim Biophys Acta , vol.1753 , Issue.2 , pp. 191-208
    • Tomoo, K.1    Matsushita, Y.2    Fujisaki, H.3    Abiko, F.4    Shen, X.5    Taniguchi, T.6    Miyagawa, H.7    Kitamura, K.8    Miura, K.9    Ishida, T.10
  • 122
    • 0037415692 scopus 로고    scopus 로고
    • The proline-rich homeodomain protein, PRH, is a tissue-specific inhibitor of eIF4E-dependent cyclin D1 mRNA transport and growth
    • Topisirovic I, Culjkovic B, Cohen N, Perez JM, Skrabanek L, Borden KL. 2003a. The proline-rich homeodomain protein, PRH, is a tissue-specific inhibitor of eIF4E-dependent cyclin D1 mRNA transport and growth. EMBO J 22(3):689-703.
    • (2003) EMBO J , vol.22 , Issue.3 , pp. 689-703
    • Topisirovic, I.1    Culjkovic, B.2    Cohen, N.3    Perez, J.M.4    Skrabanek, L.5    Borden, K.L.6
  • 123
    • 0344629665 scopus 로고    scopus 로고
    • Aberrant eukaryotic translation initiation factor 4E-dependent mRNA transport impedes hematopoietic differentiation and contributes to leukemogenesis
    • Topisirovic I, Guzman ML, McConnell MJ, Licht JD, Culjkovic B, Neering SJ, Jordan CT, Borden KL. 2003b. Aberrant eukaryotic translation initiation factor 4E-dependent mRNA transport impedes hematopoietic differentiation and contributes to leukemogenesis. Mol Cell Biol 23(24):8992-9002.
    • (2003) Mol Cell Biol , vol.23 , Issue.24 , pp. 8992-9002
    • Topisirovic, I.1    Guzman, M.L.2    McConnell, M.J.3    Licht, J.D.4    Culjkovic, B.5    Neering, S.J.6    Jordan, C.T.7    Borden, K.L.8
  • 124
    • 12844255862 scopus 로고    scopus 로고
    • Eukaryotic translation initiation factor 4E activity is modulated by HOXA9 at multiple levels
    • Topisirovic I, Kentsis A, Perez JM, Guzman ML, Jordan CT, Borden KL. 2005. Eukaryotic translation initiation factor 4E activity is modulated by HOXA9 at multiple levels. Mol Cell Biol 25(3):1100-1112.
    • (2005) Mol Cell Biol , vol.25 , Issue.3 , pp. 1100-1112
    • Topisirovic, I.1    Kentsis, A.2    Perez, J.M.3    Guzman, M.L.4    Jordan, C.T.5    Borden, K.L.6
  • 125
    • 9244228003 scopus 로고    scopus 로고
    • Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities
    • Topisirovic I, Ruiz-Gutierrez M, Borden KL. 2004. Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities. Cancer Res 64(23):8639-8642.
    • (2004) Cancer Res , vol.64 , Issue.23 , pp. 8639-8642
    • Topisirovic, I.1    Ruiz-Gutierrez, M.2    Borden, K.L.3
  • 127
    • 61749103876 scopus 로고    scopus 로고
    • Stability of eukaryotic translation initiation factor 4E mRNA is regulated by HuR, and this activity is dysregulated in cancer
    • Topisirovic I, Siddiqui N, Orolicki S, Skrabanek LA, Tremblay M, Hoang T, Borden KL. 2009b. Stability of eukaryotic translation initiation factor 4E mRNA is regulated by HuR, and this activity is dysregulated in cancer. Mol Cell Biol 29(5):1152-1162.
    • (2009) Mol Cell Biol , vol.29 , Issue.5 , pp. 1152-1162
    • Topisirovic, I.1    Siddiqui, N.2    Orolicki, S.3    Skrabanek, L.A.4    Tremblay, M.5    Hoang, T.6    Borden, K.L.7
  • 128
    • 0033862548 scopus 로고    scopus 로고
    • Phosphorylation of eIF-4E on Ser 209 in response to mitogenic and inflammatory stimuli is faithfully detected by specific antibodies
    • Tschopp C, Knauf U, Brauchle M, Zurini M, Ramage P, Glueck D, New L, Han J, Gram H. 2000. Phosphorylation of eIF-4E on Ser 209 in response to mitogenic and inflammatory stimuli is faithfully detected by specific antibodies. Mol Cell Biol Res Commun 3(4):205-211.
    • (2000) Mol Cell Biol Res Commun , vol.3 , Issue.4 , pp. 205-211
    • Tschopp, C.1    Knauf, U.2    Brauchle, M.3    Zurini, M.4    Ramage, P.5    Glueck, D.6    New, L.7    Han, J.8    Gram, H.9
  • 130
    • 3242719457 scopus 로고    scopus 로고
    • Mnk2 and Mnk1 are essential for constitutive and inducible phosphorylation of eukaryotic initiation factor 4E but not for cell growth or development
    • Ueda T, Watanabe-Fukunaga R, Fukuyama H, Nagata S, Fukunaga R. 2004. Mnk2 and Mnk1 are essential for constitutive and inducible phosphorylation of eukaryotic initiation factor 4E but not for cell growth or development. Mol Cell Biol 24(15):6539-6549.
    • (2004) Mol Cell Biol , vol.24 , Issue.15 , pp. 6539-6549
    • Ueda, T.1    Watanabe-Fukunaga, R.2    Fukuyama, H.3    Nagata, S.4    Fukunaga, R.5
  • 131
    • 77950417875 scopus 로고    scopus 로고
    • Structural characterization of the Z RING-eIF4E complex reveals a distinct mode of control for eIF4E
    • Volpon L, Osborne MJ, Capul AA, de la Torre JC, Borden KL. 2010. Structural characterization of the Z RING-eIF4E complex reveals a distinct mode of control for eIF4E. Proc Natl Acad Sci U S A 107(12):5441-5446.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.12 , pp. 5441-5446
    • Volpon, L.1    Osborne, M.J.2    Capul, A.A.3    De La Torre, J.C.4    Borden, K.L.5
  • 132
    • 0030977269 scopus 로고    scopus 로고
    • Mitogenactivated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2
    • Waskiewicz AJ, Flynn A, Proud CG, Cooper JA. 1997. Mitogenactivated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2. EMBO J 16(8):1909-1920.
    • (1997) EMBO J , vol.16 , Issue.8 , pp. 1909-1920
    • Waskiewicz, A.J.1    Flynn, A.2    Proud, C.G.3    Cooper, J.A.4
  • 134
    • 77957596297 scopus 로고    scopus 로고
    • The role of MNK proteins and eIF4E phosphorylation in breast cancer cell proliferation and survival
    • Wheater MJ, Johnson PW, Blaydes JP. 2010. The role of MNK proteins and eIF4E phosphorylation in breast cancer cell proliferation and survival. Cancer Biol Ther 10(7):728-735.
    • (2010) Cancer Biol Ther , vol.10 , Issue.7 , pp. 728-735
    • Wheater, M.J.1    Johnson, P.W.2    Blaydes, J.P.3
  • 136
    • 24044529785 scopus 로고    scopus 로고
    • Transcriptional repression of the eukaryotic initiation factor 4E gene by wild type p53
    • Zhu N, Gu L, Findley HW, Zhou M. 2005. Transcriptional repression of the eukaryotic initiation factor 4E gene by wild type p53. Biochem Biophys Res Commun 335(4):1272-1279.
    • (2005) Biochem Biophys Res Commun , vol.335 , Issue.4 , pp. 1272-1279
    • Zhu, N.1    Gu, L.2    Findley, H.W.3    Zhou, M.4


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