메뉴 건너뛰기




Volumn 42, Issue 1, 2014, Pages 172-181

Role of constitutive androstane receptor in toll-like receptor-mediated regulation of gene expression of hepatic drug-metabolizing enzymes and transporters

Author keywords

[No Author keywords available]

Indexed keywords

1,4 BIS(3,5 DICHLORO 2 PYRIDYLOXY)BENZENE; CONSTITUTIVE ANDROSTANE RECEPTOR; CYTOCHROME P450 2A4; CYTOCHROME P450 2B10; CYTOCHROME P450 3A11; DRUG METABOLIZING ENZYME; GLUCURONOSYLTRANSFERASE 1A1; LIPOPOLYSACCHARIDE; LIPOTEICHOIC ACID; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 2; SULFOTRANSFERASE; TOLL LIKE RECEPTOR; UNCLASSIFIED DRUG;

EID: 84890740280     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.113.053850     Document Type: Article
Times cited : (35)

References (34)
  • 1
    • 33144485957 scopus 로고    scopus 로고
    • Regulation of drug-metabolizing enzymes and transporters in inflammation
    • DOI 10.1146/annurev.pharmtox.46.120604.141059
    • Aitken AE, Richardson TA, and Morgan ET (2006) Regulation of drug-metabolizing enzymes and transporters in inflammation. Annu Rev Pharmacol Toxicol 46:123-149. (Pubitemid 43271186)
    • (2006) Annual Review of Pharmacology and Toxicology , vol.46 , pp. 123-149
    • Aitken, A.E.1    Richardson, T.A.2    Morgan, E.T.3
  • 3
    • 0026781930 scopus 로고
    • Interleukin-1 beta suppresses the induction of P4501A1 and P4501A2 mRNAs in isolated hepatocytes
    • Barker CW, Fagan JB, and Pasco DS (1992) Interleukin-1 beta suppresses the induction of P4501A1 and P4501A2 mRNAs in isolated hepatocytes. J Biol Chem 267:8050-8055.
    • (1992) J Biol Chem , vol.267 , pp. 8050-8055
    • Barker, C.W.1    Fagan, J.B.2    Pasco, D.S.3
  • 4
    • 33745880401 scopus 로고    scopus 로고
    • Constitutive androstane receptor (CAR) ligand, TCPOBOP, attenuates Fas-induced murine liver injury by altering Bcl-2 proteins
    • DOI 10.1002/hep.21236
    • Baskin-Bey ES, Huang W, Ishimura N, Isomoto H, Bronk SF, Braley K, Craig RW, Moore DD, and Gores GJ (2006) Constitutive androstane receptor (CAR) ligand, TCPOBOP, attenuates Fas-induced murine liver injury by altering Bcl-2 proteins. Hepatology 44:252-262. (Pubitemid 44049157)
    • (2006) Hepatology , vol.44 , Issue.1 , pp. 252-262
    • Baskin-Bey, E.S.1    Huang, W.2    Ishimura, N.3    Isomoto, H.4    Bronk, S.F.5    Braley, K.6    Craig, R.W.7    Moore, D.D.8    Gores, G.J.9
  • 5
    • 0034717067 scopus 로고    scopus 로고
    • The acute phase response is associated with retinoid X receptor repression in rodent liver
    • DOI 10.1074/jbc.M000953200
    • Beigneux AP, Moser AH, Shigenaga JK, Grunfeld C, and Feingold KR (2000) The acute phase response is associated with retinoid X receptor repression in rodent liver. J Biol Chem 275: 16390-16399. (Pubitemid 30366957)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.21 , pp. 16390-16399
    • Beigneux, A.P.1    Moser, A.H.2    Shigenaga, J.K.3    Grunfeld, C.4    Feingold, K.R.5
  • 6
    • 0036296149 scopus 로고    scopus 로고
    • Reduction in cytochrome P-450 enzyme expression is associated with repression of CAR (constitutive androstane receptor) and PXR (pregnane X receptor) in mouse liver during the acute phase response
    • DOI 10.1016/S0006-291X(02)00196-1, PII S0006291X02001961
    • Beigneux AP, Moser AH, Shigenaga JK, Grunfeld C, and Feingold KR (2002) Reduction in cytochrome P-450 enzyme expression is associated with repression of CAR (constitutive androstane receptor) and PXR (pregnane X receptor) in mouse liver during the acute phase response. Biochem Biophys Res Commun 293:145-149. (Pubitemid 34694183)
    • (2002) Biochemical and Biophysical Research Communications , vol.293 , Issue.1 , pp. 145-149
    • Beigneux, A.P.1    Moser, A.H.2    Shigenaga, J.K.3    Grunfeld, C.4    Feingold, K.R.5
  • 7
    • 0034975420 scopus 로고    scopus 로고
    • Hepatic cytochrome P450 regulation in disease states
    • DOI 10.2174/1389200013338676
    • Cheng PY, Morgan ET (2001) Hepatic cytochrome P450 regulation in disease states. Curr Drug Metab 2:165-183. (Pubitemid 32544553)
    • (2001) Current Drug Metabolism , vol.2 , Issue.2 , pp. 165-183
    • Cheng, P.-Y.1    Morgan, E.T.2
  • 8
    • 33644514010 scopus 로고    scopus 로고
    • Lipoteichoic acid increases TLR and functional chemokine expression while reducing dentin formation in in vitro differentiated human odontoblasts
    • Durand SH, Flacher V, Roméas A, Carrouel F, Colomb E, Vincent C, Magloire H, Couble ML, Bleicher F, and Staquet MJ, et al. (2006) Lipoteichoic acid increases TLR and functional chemokine expression while reducing dentin formation in in vitro differentiated human odontoblasts. J Immunol 176:2880-2887.
    • (2006) J Immunol , vol.176 , pp. 2880-2887
    • Durand, S.H.1    Flacher, V.2    Roméas, A.3    Carrouel, F.4    Colomb, E.5    Vincent, C.6    Magloire, H.7    Couble, M.L.8    Bleicher, F.9    Staquet, M.J.10
  • 9
    • 57449087449 scopus 로고    scopus 로고
    • Regulation of gene expression of hepatic drug metabolizing enzymes and transporters by the Toll-like receptor 2 ligand, lipoteichoic acid
    • Ghose R, Guo T, and Haque N (2009) Regulation of gene expression of hepatic drug metabolizing enzymes and transporters by the Toll-like receptor 2 ligand, lipoteichoic acid. Arch Biochem Biophys 481:123-130.
    • (2009) Arch Biochem Biophys , vol.481 , pp. 123-130
    • Ghose, R.1    Guo, T.2    Haque, N.3
  • 10
    • 79955048219 scopus 로고    scopus 로고
    • Differential role of Toll-interleukin 1 receptor domain-containing adaptor protein in Toll-like receptor 2-mediated regulation of gene expression of hepatic cytokines and drug-metabolizing enzymes
    • Ghose R, Guo T, Vallejo JG, and Gandhi A (2011) Differential role of Toll-interleukin 1 receptor domain-containing adaptor protein in Toll-like receptor 2-mediated regulation of gene expression of hepatic cytokines and drug-metabolizing enzymes. Drug Metab Dispos 39: 874-881.
    • (2011) Drug Metab Dispos , vol.39 , pp. 874-881
    • Ghose, R.1    Guo, T.2    Vallejo, J.G.3    Gandhi, A.4
  • 11
    • 37549043182 scopus 로고    scopus 로고
    • Regulation of hepatic drug-metabolizing enzyme genes by Toll-like receptor 4 signaling is independent of Toll-interleukin 1 receptor domain-containing adaptor protein
    • Ghose R, White D, Guo T, Vallejo J, and Karpen SJ (2008) Regulation of hepatic drug-metabolizing enzyme genes by Toll-like receptor 4 signaling is independent of Toll-interleukin 1 receptor domain-containing adaptor protein. Drug Metab Dispos 36:95-101.
    • (2008) Drug Metab Dispos , vol.36 , pp. 95-101
    • Ghose, R.1    White, D.2    Guo, T.3    Vallejo, J.4    Karpen, S.J.5
  • 12
    • 18144387309 scopus 로고    scopus 로고
    • Endotoxin leads to rapid subcellular re-localization of hepatic RXRalpha: A novel mechanism for reduced hepatic gene expression in inflammation
    • Ghose R, Zimmerman TL, Thevananther S, and Karpen SJ (2004) Endotoxin leads to rapid subcellular re-localization of hepatic RXRalpha: a novel mechanism for reduced hepatic gene expression in inflammation. Nucl Recept 2:4.
    • (2004) Nucl Recept , vol.2 , pp. 4
    • Ghose, R.1    Zimmerman, T.L.2    Thevananther, S.3    Karpen, S.J.4
  • 13
    • 0035115303 scopus 로고    scopus 로고
    • Regulation of the hepatic multidrug resistance gene expression by endotoxin and inflammatory cytokines in mice
    • DOI 10.1016/S0162-3109(00)00271-X, PII S016231090000271X
    • Hartmann G, Kim H, and Piquette-Miller M (2001) Regulation of the hepatic multidrug resistance gene expression by endotoxin and inflammatory cytokines in mice. Int Immunopharmacol 1: 189-199. (Pubitemid 32183718)
    • (2001) International Immunopharmacology , vol.1 , Issue.2 , pp. 189-199
    • Hartmann, G.1    Kim, H.2    Piquette-Miller, M.3
  • 14
    • 0026907220 scopus 로고
    • Deposition of circulating streptococcal lip-oteichoic acid in mouse tissues
    • Hyzy J, Sciotti V, Albini B, and Stinson M (1992) Deposition of circulating streptococcal lip-oteichoic acid in mouse tissues. Microb Pathog 13:123-132.
    • (1992) Microb Pathog , vol.13 , pp. 123-132
    • Hyzy, J.1    Sciotti, V.2    Albini, B.3    Stinson, M.4
  • 16
    • 52449108842 scopus 로고    scopus 로고
    • New insights on the xenobiotic-sensing nuclear receptors in liver diseases-CAR and PXR
    • Kakizaki S, Yamazaki Y, Takizawa D, and Negishi M (2008) New insights on the xenobiotic-sensing nuclear receptors in liver diseases-CAR and PXR-. Curr Drug Metab 9: 614-621.
    • (2008) Curr Drug Metab , vol.9 , pp. 614-621
    • Kakizaki, S.1    Yamazaki, Y.2    Takizawa, D.3    Negishi, M.4
  • 17
    • 0037200089 scopus 로고    scopus 로고
    • Interleukin-1-mediated suppression of RXR:RAR transactivation of the Ntcp promoter is JNK-dependent
    • DOI 10.1074/jbc.M204818200
    • Li D, Zimmerman TL, Thevananther S, Lee HY, Kurie JM, and Karpen SJ (2002) Interleukin-1 beta-mediated suppression of RXR:RAR transactivation of the Ntcp promoter is JNK-de-pendent. J Biol Chem 277:31416-31422. (Pubitemid 34968941)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.35 , pp. 31416-31422
    • Li, D.1    Zimmerman, T.L.2    Thevananther, S.3    Lee, H.-Y.4    Kurie, J.M.5    Karpen, S.J.6
  • 19
    • 0029562554 scopus 로고
    • The RXR heterodimers and orphan receptors
    • DOI 10.1016/0092-8674(95)90200-7
    • Mangelsdorf DJ and Evans RM (1995) The RXR heterodimers and orphan receptors. Cell 83: 841-850. (Pubitemid 26006526)
    • (1995) Cell , vol.83 , Issue.6 , pp. 841-850
    • Mangelsdorf, D.J.1    Evans, R.M.2
  • 20
    • 0037954044 scopus 로고    scopus 로고
    • TRAF6-NF-B pathway is essential for interleukin-1-induced TLR2 expression and its functional response to TLR2 ligand in murine hepatocytes
    • DOI 10.1046/j.1365-2567.2003.01627.x
    • Matsumura T, Degawa T, Takii T, Hayashi H, Okamoto T, Inoue J, and Onozaki K (2003) TRAF6-NF-kappaB pathway is essential for interleukin-1-induced TLR2 expression and its functional response to TLR2 ligand in murine hepatocytes. Immunology 109:127-136. (Pubitemid 36577983)
    • (2003) Immunology , vol.109 , Issue.1 , pp. 127-136
    • Matsumura, T.1    Degawa, T.2    Takii, T.3    Hayashi, H.4    Okamoto, T.5    Inoue, J.-I.6    Onozaki, K.7
  • 21
    • 0029126915 scopus 로고
    • Differential effects of cytokines on the inducible expression of CYP1A1, CYP1A2, and CYP3A4 in human hepatocytes in primary culture
    • Muntané-Relat J, Ourlin JC, Domergue J, and Maurel P (1995) Differential effects of cytokines on the inducible expression of CYP1A1, CYP1A2, and CYP3A4 in human hepatocytes in primary culture. Hepatology 22:1143-1153.
    • (1995) Hepatology , vol.22 , pp. 1143-1153
    • Muntané-Relat, J.1    Ourlin, J.C.2    Domergue, J.3    Maurel, P.4
  • 22
    • 0344082190 scopus 로고    scopus 로고
    • Porin of Shigella dysenteriae enhances mRNA levels for Toll-like receptor 2 and MyD88, up-regulates CD80 of murine macrophage, and induces the release of interleukin-12
    • DOI 10.1016/S0928-8244(03)00233-5
    • Ray A, Chatterjee NS, Bhattacharya SK, and Biswas T (2003) Porin of Shigella dysenteriae enhances mRNA levels for Toll-like receptor 2 and MyD88, up-regulates CD80 of murine macrophage, and induces the release of interleukin-12. FEMS Immunol Med Microbiol 39:213-219. (Pubitemid 37461000)
    • (2003) FEMS Immunology and Medical Microbiology , vol.39 , Issue.3 , pp. 213-219
    • Ray, A.1    Chatterjee, N.S.2    Bhattacharya, S.K.3    Biswas, T.4
  • 23
    • 2942557103 scopus 로고    scopus 로고
    • Cytochrome P450 regulation and drug biotransformation during inflammation and infection
    • DOI 10.2174/1389200043335559
    • Renton KW (2004) Cytochrome P450 regulation and drug biotransformation during inflammation and infection. Curr Drug Metab 5:235-243. (Pubitemid 38735778)
    • (2004) Current Drug Metabolism , vol.5 , Issue.3 , pp. 235-243
    • Renton, K.W.1
  • 24
    • 0033940547 scopus 로고    scopus 로고
    • Hepatic and central nervous system cytochrome P450 are down-regulated during lipopolysaccharide-evoked localized inflammation in brain
    • Renton KW and Nicholson TE (2000) Hepatic and central nervous system cytochrome P450 are down-regulated during lipopolysaccharide-evoked localized inflammation in brain. J Pharmacol Exp Ther 294:524-530. (Pubitemid 30490825)
    • (2000) Journal of Pharmacology and Experimental Therapeutics , vol.294 , Issue.2 , pp. 524-530
    • Renton, K.W.1    Nicholson, T.E.2
  • 25
    • 22944474949 scopus 로고    scopus 로고
    • Hepatic cytochrome P450 gene regulation during endotoxin-induced inflammation in nuclear receptor knockout mice
    • DOI 10.1124/jpet.105.085456
    • Richardson TA and Morgan ET (2005) Hepatic cytochrome P450 gene regulation during endotoxin-induced inflammation in nuclear receptor knockout mice. J Pharmacol Exp Ther 314:703-709. (Pubitemid 41043852)
    • (2005) Journal of Pharmacology and Experimental Therapeutics , vol.314 , Issue.2 , pp. 703-709
    • Richardson, T.A.1    Morgan, E.T.2
  • 26
    • 33646347356 scopus 로고    scopus 로고
    • Toll-Like Receptor Signaling in the Liver
    • DOI 10.1053/j.gastro.2006.01.038, PII S0016508506000655
    • Schwabe RF, Seki E, and Brenner DA (2006) Toll-like receptor signaling in the liver. Gastro-enterology 130:1886-1900. (Pubitemid 43668871)
    • (2006) Gastroenterology , vol.130 , Issue.6 , pp. 1886-1900
    • Schwabe, R.F.1    Seki, E.2    Brenner, D.A.3
  • 27
    • 0030986165 scopus 로고    scopus 로고
    • Differential inductive and suppressive effects of endotoxin and particulate irritants on hepatic and renal cytochrome P-450 expression
    • Sewer MB, Koop DR, and Morgan ET (1997) Differential inductive and suppressive effects of endotoxin and particulate irritants on hepatic and renal cytochrome P-450 expression. J Pharmacol Exp Ther 280:1445-1454. (Pubitemid 27166743)
    • (1997) Journal of Pharmacology and Experimental Therapeutics , vol.280 , Issue.3 , pp. 1445-1454
    • Sewer, M.B.1    Koop, D.R.2    Morgan, E.T.3
  • 28
    • 70349952430 scopus 로고    scopus 로고
    • Nrf2 plays an important role in coordinated regulation of Phase II drug metabolism enzymes and Phase III drug transporters
    • Shen G and Kong AN (2009) Nrf2 plays an important role in coordinated regulation of Phase II drug metabolism enzymes and Phase III drug transporters. Biopharm Drug Dispos 30:345-355.
    • (2009) Biopharm Drug Dispos , vol.30 , pp. 345-355
    • Shen, G.1    Kong, A.N.2
  • 29
    • 0035727442 scopus 로고    scopus 로고
    • Regulation of innate immune responses by toll-like receptors
    • Takeda K and Akira S (2001) Regulation of innate immune responses by Toll-like receptors. Jpn J Infect Dis 54:209-219. (Pubitemid 34285466)
    • (2001) Japanese Journal of Infectious Diseases , vol.54 , Issue.6 , pp. 209-219
    • Takeda, K.1    Akira, S.2
  • 30
    • 13244258414 scopus 로고    scopus 로고
    • The involvement of the pregnane X receptor in hepatic gene regulation during inflammation in mice
    • DOI 10.1124/jpet.104.076141
    • Teng S and Piquette-Miller M (2005) The involvement of the pregnane X receptor in hepatic gene regulation during inflammation in mice. J Pharmacol Exp Ther 312:841-848. (Pubitemid 40189587)
    • (2005) Journal of Pharmacology and Experimental Therapeutics , vol.312 , Issue.2 , pp. 841-848
    • Teng, S.1    Piquette-Miller, M.2
  • 31
    • 33751568515 scopus 로고    scopus 로고
    • Nuclear receptors CAR and PXR in the regulation of hepatic metabolism
    • DOI 10.1080/00498250600861827, PII Q41067521857X895
    • Tien ES and Negishi M (2006) Nuclear receptors CAR and PXR in the regulation of hepatic metabolism. Xenobiotica 36:1152-1163. (Pubitemid 44844116)
    • (2006) Xenobiotica , vol.36 , Issue.10-11 , pp. 1152-1163
    • Tien, E.S.1    Negishi, M.2
  • 32
    • 0034687397 scopus 로고    scopus 로고
    • The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism
    • Wei P, Zhang J, Egan-Hafley M, Liang S, and Moore DD (2000) The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism. Nature 407:920-923.
    • (2000) Nature , vol.407 , pp. 920-923
    • Wei, P.1    Zhang, J.2    Egan-Hafley, M.3    Liang, S.4    Moore, D.D.5
  • 33
    • 0037064177 scopus 로고    scopus 로고
    • Modulation of acetaminophen-induced hepatotoxicity by the xenobiotic receptor CAR
    • DOI 10.1126/science.1073502
    • Zhang J, Huang W, Chua SS, Wei P, and Moore DD (2002) Modulation of acetaminophen-induced hepatotoxicity by the xenobiotic receptor CAR. Science 298:422-424. (Pubitemid 35176352)
    • (2002) Science , vol.298 , Issue.5592 , pp. 422-424
    • Zhang, J.1    Huang, W.2    Chua, S.S.3    Wei, P.4    Moore, D.D.5
  • 34
    • 65549089505 scopus 로고    scopus 로고
    • Role of NF-kappaB in the regulation of cytochrome P450 enzymes
    • Zordoky BN and El-Kadi AO (2009) Role of NF-kappaB in the regulation of cytochrome P450 enzymes. Curr Drug Metab 10:164-178.
    • (2009) Curr Drug Metab , vol.10 , pp. 164-178
    • Zordoky, B.N.1    El-Kadi, A.O.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.