Functional transcriptome analysis of the postnatal brain of the Ts1Cje mouse model for Down syndrome reveals global disruption of interferon-related molecular networks

BMC Genomics

Volumn 15, Issue 1, 2014, Pages

  Ling, King Hwa ^a,b   Hewitt, Chelsee A ^b,c   Tan, Kai Leng ^a   Cheah, Pike See ^a   Vidyadaran, Sharmili ^a   Lai, Mei I ^a   Lee, Han Chung ^a   Simpson, Ken ^b   Hyde, Lavinia ^b   Pritchard, Melanie A ^d   Smyth, Gordon K ^b   Thomas, Tim ^b   Scott, Hamish S ^b,e,f  

^a UPM   (Malaysia)

^b WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c PETER MACCALLUM CANCER CENTRE   (Australia)

^d MONASH UNIVERSITY   (Australia)

^e An alliance between SA Pathology and the University of South Australia   (Australia)

^f UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON; INTERFERON RECEPTOR; PROTEIN IFNAR1; STAT1 PROTEIN; TRANSCRIPTOME; UNCLASSIFIED DRUG; ALPHA BETA INTERFERON RECEPTOR; IFNAR1 PROTEIN, MOUSE; JANUS KINASE; STAT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATP5O GENE; BRAIN CORTEX; BRAIN DEVELOPMENT; BRWD1 GENE; CBR1 GENE; CEREBELLUM; CHROMOSOME 16; CONTROLLED STUDY; DONSON GENE; DOPEY2 GENE; DOWN SYNDROME; ERDR1 GENE; GENE; GENE CLUSTER; GENE EXPRESSION; GENE EXPRESSION PROFILING; HIPPOCAMPUS; HMGN1 GENE; IFNAR1 GENE; IFNAR2 GENE; IFNGR2 GENE; ITGB8 GENE; ITSN1 GENE; MORC3 GENE; MOUSE; MRPS6 GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARTIAL TRISOMY; PAXBP1 GENE; POSTNATAL DEVELOPMENT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SON GENE; STAT1 GENE; TBATA GENE; TMEM50B GENE; WESTERN BLOTTING; WRB GENE; ANIMAL; BRAIN; C57BL MOUSE; CLUSTER ANALYSIS; DISEASE MODEL; DNA MICROARRAY; FEMALE; GENETICS; MALE; METABOLISM; REAL TIME POLYMERASE CHAIN REACTION; TRISOMY; ADULT; GENE OVEREXPRESSION; GENETIC IDENTIFICATION; MICROARRAY ANALYSIS; MOUSE MODEL; PERINATAL PERIOD; TRANSCRIPTOMICS;

MUS;

ANIMALS; BRAIN; CEREBRAL CORTEX; CLUSTER ANALYSIS; DISEASE MODELS, ANIMAL; DOWN SYNDROME; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; HIPPOCAMPUS; INTERFERONS; JANUS KINASES; MALE; MICE; MICE, INBRED C57BL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTOR, INTERFERON ALPHA-BETA; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; TRISOMY;

EID: 84904517120     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-15-624     Document Type: Article

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