Enlarged brain ventricles and impaired neurogenesis in the Ts1Cje and Ts2Cje mouse models of down syndrome

Cerebral Cortex

Volumn 20, Issue 5, 2010, Pages 1131-1143

  Ishihara, Keiichi ^a,d   Amano, Kenji ^a   Takaki, Eiichi ^a   Shimohata, Atsushi ^a   Sago, Haruhiko ^b   J Epstein, Charles ^c   Yamakawa, Kazuhiro ^a  

^a RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^b NATIONAL CENTER FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Adult neurogenesis; Developmental retardation; Neocortical neurogenesis; Trisomy 21

Indexed keywords

BROXURIDINE; DOUBLECORTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN VENTRICLE; CELL PROLIFERATION; CHROMOSOME 16; CHROMOSOME 21; CONGENITAL MALFORMATION; CONTROLLED STUDY; DENTATE GYRUS; DIPLOIDY; DOWN SYNDROME; HISTOPATHOLOGY; LATERAL BRAIN VENTRICLE; MENTAL DEFICIENCY; MOUSE; MOUSE STRAIN; MOUSE STRAIN TS1CJE; MOUSE STRAIN TS2CJE; NERVOUS SYSTEM DEVELOPMENT; NEUROBLAST; NONHUMAN; PRIORITY JOURNAL; SUBVENTRICULAR ZONE; TRISOMY;

ANIMALS; CELL PROLIFERATION; CEREBRAL VENTRICLES; CHROMOSOMES, HUMAN, PAIR 21; CHROMOSOMES, MAMMALIAN; DISEASE MODELS, ANIMAL; DOWN SYNDROME; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROTUBULE-ASSOCIATED PROTEINS; NEUROGENESIS; NEUROPEPTIDES; PREGNANCY; TRISOMY;

EID: 77951096438     PISSN: 10473211     EISSN: 14602199     Source Type: Journal    
DOI: 10.1093/cercor/bhp176     Document Type: Article

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