Erratum: Mice deficient for the chromosome 21 ortholog Itsn1 exhibit vesicle-trafficking abnormalities (Human Molecular Genetic (2008) vol. 17(21) (3281-3290) 10.1093/hmg/ddn224);Mice deficient for the chromosome 21 ortholog Itsn1 exhibit vesicle-trafficking abnormalities

Human Molecular Genetics

Volumn 17, Issue 21, 2008, Pages 3281-3290

  Yu, Yong ^a   Chu, Po Yin ^b,c   Bowser, David N ^b,c   Keating, Damien J ^d,e   Dubach, Daphne ^a   Harper, Ian ^a   Tkalcevic, Josephine ^a   Finkelstein, David I ^c   Pritchard, Melanie A ^a  

^a MONASH UNIVERSITY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH   (Australia)

^d HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

^e FLINDERS UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

INTERSECTIN; INTERSECTIN 1; NERVE GROWTH FACTOR; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHROMAFFIN CELL; CHROMOSOME 21; CONTROLLED STUDY; DOWN SYNDROME; ENDOCYTOSIS; ENDOSOME; EXOCYTOSIS; FETUS; GENE DISRUPTION; GENE IDENTIFICATION; KNOCKOUT MOUSE; MOUSE; NERVE CELL; NONHUMAN; ORTHOLOGY; PRIORITY JOURNAL; PROTEIN FUNCTION; SEPTUM PELLUCIDUM; TRANSPORT VESICLE; UPREGULATION;

MAMMALIA; MUS;

EID: 54449083655     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddn378     Document Type: Erratum

References (41)

1. Epstein, C.J. (1995) The Metabolic and Molecular Bases of Inherited Disease, 7th edn. McGraw-Hill, New York, NY.
2. Mann, D.M. (1988) The pathological association between Down syndrome and Alzheimer disease. Mech. Ageing Dev., 43, 99-136.
3. Cataldo, A.M., Peterhoff, C.M., Troncoso, J.C., Gomez-Isla, T., Hyman, B.T. and Nixon, R.A. (2000) Endocytic pathway abnormalities precede amyloid beta. deposition in sporadic Alzheimer's disease and Down syndrome: Differential effects of APOE genotype and presenilin mutations. Am. J. Pathol., 157, 277-286.
4. Cataldo, A.M., Petanceska, S., Peterhoff, C.M., Terio, N.B., Epstein, C.J., Villar, A., Carlson, E.J., Staufenbiel, M. and Nixon, R.A. (2003) App gene dosage modulates endosomal abnormalities of Alzheimer's distase in a segmental trisomy 16 mouse model of down syndrome. J. Neurosci. 23, 6788-6792.
5. Nixon, R.A. (2005) Endosome function and dysfunction in Alzheirner's disease and other neurodegenerativc diseases. Neurobiol. Aging, 26, 373-382.
6. Grbovic, O.M., Mathews, P.M., Jiang, Y., Schmidt, S.D., Dinakar, R., Summers-Terio, N.B., Ceresa, B.P., Nixon, R.A. and Cataldo, A.M. (2003) Rab5-stimulatcd up-regulation of the endocytic pathway increases intracellular beta-cleaved amyloid precursor protein carboxyl-terminal fragment levels and Abeta production. J. Biol. Chem., 278, 31261-31268.
7. Pucharcos, C., Fuentes, J.J., Casas, C., de la Luna, S., Alcantara, S., Arbones, M.L., Soriano, E., Estivill, X. and Pritchard, M. (1999) Alu-splice cloning of human Intersectin (ITSN), a putative multivalent binding protein expressed in proliferating and differenting neurons and overexpressed in Down syndrome. Eur. J. Hum. Genet., 7, 704-712.
8. Fuentes, J.J., Dierssen, M., Pucharcos, C., Fillat, C., Casas, C., Estivill, X. and Pritchard, M. (1999) Application of Alu-splice PCR on chromosome 21: DSCR1 and Intersectin. J. Neural Transm. Suppl., 57, 337-352.
9. Boguski, M.S. and McCormick, F. (1993) Proteins regulating Ras and its relatives. Nature, 366, 643-654.
10. Shaw, G. (1996) The pleckstrin homology domain: An intriguing multifunctional protein module. Bioessays, 18, 35-46.
11. Yamabhai, M., Hoffman, N.G., Hardison, N.L., McPherson, P.S., Castagnol, L., Cesaren, G. and Kay, B.K. (1998) Intersectin, a novel adaptor protein with two epsl5 homology and five src homology 3 domains. J. Biol. Chem., 273, 31401-31407.
12. Hussain, N.K., Yamabhai, M., Ramjaun, A.R., Guy, A.M., Baranes, D., O'Bryan, J.P., Der, C.J., Kay, B.K. and McPherson, P.S. (1999) Splice variants of intersectin are components of the endocytic machinery in neurons and nonneuronal cells. J. Biol. Chem., 274, 15671-15677.
13. Sengar, A.S., Wang, W., Bishay, J., Cohen, S. and Egan, S.E. (1999) The EH and SH3 domain Esc proteins regulate endocylosis by linking to dynamin and Eps15. EMBO J., 18, 1159-1171.
14. Adams, A., Thom, J.M., Yamabhai, M., Kay, B.K. and O'Bryan, J.P. (2000) Intersectin, an adaptor protein involved in clathrin-mediated endocytosis, activates mitogenic signaling pathways. J. Biol. Chem. 275, 27414-27420.
15. Mohney, R.P., Das, M., Bivona, T.G., Hanes, R., Adams, A.G., Philips, M.R. and O'Bryan, J.P. (2003) Intersectin activates Ras but stimulates transcription through an independent pathway involving JNK. J. Biol. Chem., 278, 47038-47045.
16. Tong, X.K., Hussain, N.K., de Heuvel, E., Kurakin, A., Abi-Jaoude, E., Quinn, C.C., Olson, M.F., Marais, R., Baranes, D. and Kay, B.K. (2000) The endocytic protein intersectin is a major binding partner for the Ras exchange factor mSos1 in rat brain. EMBO J., 19, 1263-1271.
17. Tong, X.K., Hussain, N.K., Adams, A.G., O'Bryan, J.P. and McPherson, P.S. (2000) Intersectin can regulate the Ras/MAP kinase pathway independent of its role in endocytosis. J. Biol. Chem., 275, 29894-29899.
18. Hussain, N.K., Jenna, S., Glogauer, M., Quinn, C.C., Wasiak, S., Guipponi, M., Antonarakis, S.E., Kay, B.K., Stossel, T.P., Lamarche-Vane, N. et al. (2001) Endocytic protein intersectin-1 regulates actin assembly via Cdc42 and N-WASP. Nat. Cell Biol., 3, 927-932.
19. Martin, N.P., Mohney, R.P., Dunn, S., Das, M., Scappini, E. and O'Bryan, J.P. (2006) Intersectin regulates epidermal growth factor receptor endocytosis, ubiquitylation, and signaling. Mol. Pharmacol., 70 1643-1653.
20. Das, M., Scappird, E., Martin, N.P., Wong, K.A., Dunn, S., Chen, Y.J., Miller, S.L., Domin, J. and O'Bryan, J.P. (2007) Regulation of neuron survival through an intersectin-phosphoinositide 3′-kinase C2beta-AKT pathway. Mol. Cell. Biol., 27, 7906-7917.
21. Malacombe, M., Ceridono, M., Calco, V., Chasserot-Golaz, S., McPherson, P.S., Bader, M.F. and Gasman, S. (2006) Intersectin-1L, nucleotide exchange factor regulates secretory granule exocytosis by activating Cdc42. EMBO J, 25, 3494-3503.
22. Predescu, S.A., Predescu, D.N., Knezevic, I., Klein, I.K. and Malik, A.B. (2007) Intersectin-1s regulates the mitochondrial apoptotic pathway in endothchal cells. J. Biol. Chem., 282, 17166-17178.
23. Koh, T.W., Verstreken, P. and Bellen, H.J. (2004) Dap160/intersectin acts as a stabilizing scaffold required for synaptic development and vesicle endocytosis. Neuron, 43, 193-205.
24. Marie, B., Sweeney, S.T., Poskanzer, K.E., Roos, J., Kelly, R.B. and Davis, G.W. (2004) Dap160/intersectin scaffolds the periactive zone to achieve high-fidelity endocytosis and normal synaptic growth. Neuron 43, 207-219.
25. Ma, Y.J., Okamoto, M., Gu, F., Obata, K., Matsuyama, T., Desaki, J., Tanaka, J. and Sakanaka, M. (2003) Neuronal distribution of EHSH1/ intersectin: Molecular linker between clathrin-mediated endocytosis and signaling pathways. J. Neurosci. Res., 71, 468-477.
26. Gandhi, S.P. and Stevens, C.F. (2003) Three modes of synaptic vesicular recycling revealed by single-vesicle imaging. Nature, 423, 607-613.
27. Granseth, B., Odermatt, B., Royle, S.J. and Lagnado, L. (2006) Clathrin-mediated endocytosis is the dominant mechanism of vesicle retrieval at hippocampal synapses. Neuron, 51, 773-786.
28. Sofroniew, M.V., Howe, C.L. and Mobley, W.C. (2001) Nerve growth factor signaling, neuroprotection, and neural repair. Annu. Rev. Neurosci. 24, 1217-1281.
29. Cooper, J.D., Salehi, A., Delcroix, J.D., Howe, C.L., Belichenko, P.V., Chua-Couzens, J., Kilbridge, J.F., Carlson, E.J., Epstein, C.J. and Mobley, W.C. (2001) Failed retrograde transport of NGF in a mouse model of Down's syndrome: Reversal of cholinergic neurodegenerative phenotypes following NGF infusion. Proc. Natl. Acad. Sci. USA, 98, 10439-10444.
30. Di Paolo, G., Sankaranarayanan, S., Wenk, M.R., Daniell, L., Perucco, E., Caldarone, B.J., Flavell, R., Picciotto, M.R., Ryan, T.A., Cremona, O. et al. (2002) Decreased synaptic vesicle recycling efficiency and cognitive deficits in amphiphysin 1 knockout mice. Neuron, 33, 789-804.
31. Spiwoks-Becker, I., Vollrath, L., Seeliger, M.W., Jaissle, G., Eshkind, L.G. and Leube, R.E. (2001) Synaptic vesicle alterations in rod photoreceptors, of synaptophysin-deficient mice. Neuroscience, 107, 127-142.
32. Gardiner, K., Fortna, A., Bechtel, L. and Davisson, M.T. (2003) Mouse models of Down syndrome: How useful can they be? Comparison of the gene content of human chromosome 21 with orthologous mouse genomic regions. Gene, 318, 137-147.
33. Keating, D.J., Dubach, D., Yu, Y., Martin, K.R., Zhao, Y.F., Chen, C., Porta, S., Arbonés, M.L., Mittaz, L. and Pritchard, M.A. (2008) DSCR1/RCAN1 regulates vesicle exocytosis and fusion pore kinetics: implications for Down syndrome and Alzheimer's disease. Hum. Mol. Genet, 17, 1020-1030.
34. Keating, D.J., Chen, C. and Pritchard, M.A. (2006) Alzheimer's disease and endocytic dysfunction: Clues from the Down syndrome-related proteins, DSCR1 and ITSN1. Ageing Res. Rev., 5, 388-401.
35. Arron, J.R., Winslow, M.M., Polleri, A., Chang, C.P., Wu, H., Gao, X., Neilson, J.R., Chen, L., Heit, J.J., Kim, S.K. et al. (2006) NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21. Nature, 441, 595-600.
36. Salehi, A., Delcroix, J.D., Belichenko, P.V., Zhan, K., Wu, C., Valletta, J.S., Takimoto-Kimura, R., Kleschevnikov, A.M., Sambamurti, K., Chung, P.P. et al. (2006) Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration. Neuron, 51, 29-42.
37. Mani, M., Lee, S.Y., Lucast, L., Cremona, O., Di Paolo, G., De Camilli, P. and Ryan, T.A. (2007) The dual phosphatase activity of synaptojanin1 is required for both efficient synaptic vesicle endocytosis and reavailability at nerve terminals. Neuron, 56, 1004-1018.
38. Chow, R.H., von Ruden, L. and Neher, E. (1992) Delay in vesicle fusion revealed by electrochemical monitoring of single secretory events in adrenal chromaffin cells. Nature, 356, 60-63.
39. Colliver, T.L., Pyott, S.J., Achalabun, M. and Ewing, A.G. (2000) VMAT-mediated changes in quantal size and vesicular volume. J. Neurosci., 20, 5276-5282.
40. Miesenbock, G., De Angelis, D.A. and Rothman, J.E. (1998) Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins. Nature, 394, 192-195.
41. Bowser, D.N. and Khakh, B.S. (2007) Two forms of single-vesicle astrocyte exocytosis imaged with total internal reflection fluorescence microscopy. Proc. Natl. Acad. Sci. USA, 104, 4212-4217.