Proliferation deficits and gene expression dysregulation in Down's syndrome (Ts1Cje) neural progenitor cells cultured from neurospheres

Journal of Neuroscience Research

Volumn 87, Issue 14, 2009, Pages 3143-3152

  Moldrich, Randal X ^a,b   Dauphinot, Luce ^a,g   Laffaire, Julien ^a,g   Vitalis, Tania ^a   Hérault, Yann ^c   Beart, Philip M ^d   Rossier, Jean ^a   Vivien, Denis ^e   Gehrig, Corinne ^f   Antonarakis, Stylianos E ^f   Lyle, Robert ^f   Potier, Marie Claude ^a,g  

^a CNRS   (France)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c UNIVERSITÉ D'ORLÉANS   (France)

^d UNIVERSITY OF MELBOURNE   (Australia)

^e INSERM   (France)

^f UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^g PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

Down's syndrome; Gene expression; Neocortex; Neural progenitor cells; Neurosphere; Proliferation; Ts1Cje

Indexed keywords

6 PHOSPHOFRUCTO 2 KINASE; AMYLOID PRECURSOR PROTEIN; CALCIUM BINDING AND COILED COIL DOMAIN 1; COPPER ZINC SUPEROXIDE DISMUTASE; CYCLIN DEPENDENT KINASE 1; DELTA LIKE 1 PROTEIN; GLIAL FIBRILLARY ACIDIC PROTEIN; HEAT STABLE ANTIGEN 1; METALLOTHIONEIN I; OLIGODENDROCYTE TRANSCRIPTION FACTOR 1; OLIGODENDROCYTE TRANSCRIPTION FACTOR 2; PROTEIN DYRK1A; PROTEIN MMU16; PROTEIN SOX21; REGULATOR PROTEIN; SOMATOMEDIN BINDING PROTEIN 2; TRANSCRIPTION FACTOR PBX1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL MODEL; ARTICLE; CELL CYCLE REGULATION; CELL FUNCTION; CELL PROLIFERATION; CHROMOSOME 21; CONTROLLED STUDY; DIPLOIDY; DOWN SYNDROME; EMBRYO; GENE EXPRESSION PROFILING; GENETIC ANALYSIS; IMMUNOCYTOCHEMISTRY; MOUSE; NEOCORTEX; NERVE CELL DIFFERENTIATION; NERVE CELL NECROSIS; NEURAL STEM CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; TRIPLOIDY;

ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DOWN SYNDROME; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENOTYPE; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICROSPHERES; NEOCORTEX; NEUROGLIA; NEURONS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STEM CELLS;

EID: 70449469558     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22131     Document Type: Article

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