Enhanced activity of adenine-DNA glycosylase (Myh) by apurinic/apyrimidinic endonuclease (Ape1) in mammalian base excision repair of an A/GO mismatch

Nucleic Acids Research

Volumn 29, Issue 3, 2001, Pages 743-752

  Yang, Hanjing ^a   Clendenin, Wendy M ^a   Wong, Donny ^b   Demple, Bruce ^b   Slupska, Malgorzata M ^a   Chiang, Ju Huei ^a   Miller, Jeffrey H ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c 1602 Molecular Sciences Building ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYGUANINE; ADENINE; CYTOSINE; DNA; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; DNA GLYCOSYLTRANSFERASE; GUANINE; LYASE; MUTANT PROTEIN; THYMINE;

AMINO ACID SEQUENCE; ARTICLE; BASE MISPAIRING; CATALYSIS; CONTROLLED STUDY; DNA CLEAVAGE; DNA PROTEIN COMPLEX; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME MECHANISM; ESCHERICHIA COLI; EXCISION REPAIR; IN VIVO STUDY; MAMMAL; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; OXIDATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY;

ESCHERICHIA COLI; MAMMALIA; MURINAE; NEGIBACTERIA; ZIZIPHUS MAURITIANA;

EID: 0035253515     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/29.3.743     Document Type: Article

References (48)

1. Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG
2. Site-specific mutagenesis using a gapped duplex vector: A study of translesion synthesis past 8-oxodeoxyguanosine in E. coli
3. DNA replication fidelity with 8-oxodeoxyguanosine triphosphate
4. The mutY gene: A mutator locus in Escherichia coli that generates G.C→T.A transversions
5. Evidence that MutY and MutM combine to prevent mutations by an oxidatively damaged form of guanine in DNA
6. A repair system for 8-oxo-7,8-dihydrodeoxyguanine
7. Envisioning the molecular choreography of DNA base excision repair
8. DNA repair mechanisms for the recognition and removal of damaged DNA bases
9. Nucleotide sequence of the nfo gene of Escherichia coli K-12
10. Structure of the DNA repair enzyme endonuclease IV and its DNA complex: Double-nucleotide flipping at abasic sites and three-metal-ion catalysis
11. Endonuclease II of Escherichia coli is exonuclease III
12. Structure and function of the multifunctional DNA-repair enzyme exonuclease III
13. A novel nucleotide excision repair for the conversion of an A/G mismatch to C/G base pair in E. coli
14. Escherichia coli mutY gene encodes an adenine glycosylase active on G-A mispairs
15. Single-turnover and pre-steady-state kinetics of the reaction of the adenine glycosylase MutY with mismatch-containing DNA substrates
16. The C-terminal domain of the adenine-DNA glycosylase MutY confers specificity for 8-oxoguanine.adenine mispairs and may have evolved from MutT, an 8-oxo-dGTPase
17. The C-terminal domain of MutY glycosylase determines the 7,8-dihydro-8-oxo-guanine specificity and is crucial for mutation avoidance
18. Identification of the structural and functional domains of MutY, an Escherichia coli DNA mismatch repair enzyme
19. MutY catalytic core, mutant and bound adenine structures define specificity for DNA repair enzyme superfamily
20. Escherichia coli MutY protein has both N-glycosylase and apurinic/apyrimidinic endonuclease activities on A.C and A.G. mispairs
21. MutY DNA glycosylase: Base release and intermediate complex formation
22. Evidence that MutY is a monofunctional glycosylase capable of forming a covalent Schiff base intermediate with substrate DNA
23. Formation of a Schiff base intermediate is not required for the adenine glycosylase activity of Escherichia coli MutY
24. Unified catalytic mechanism for DNA glycosylases
25. Characterization of the recombinant MutY homolog, an adenine DNA glycosylase, from yeast Schizosaccharomyces pombe
26. Cloning and sequencing a human homolog (hMYH) of the Escherichia coli mutY gene whose function is required for the repair of oxidative DNA damage
27. Functional expression of hMYH, a human homolog of the Escherichia coli mutY protein
28. Differential subcellular localization of human MutY homolog (hMYH) and the functional activity of adenine: 8-oxoguanine DNA glycosylase
29. Identification of human MutY homolog (hMYH) as a repair enzyme for 2-hydroxyadenine in DNA and detection of multiple forms of hMYH located in nucleic and mitochondria
30. Nuclear localization of the human mutY homologue hMYH
31. The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites
32. DNA-bound structures and mutants reveal abasic DNA binding by APE1 DNA repair and coordination
33. Life without DNA repair
34. Specific interaction of DNA polymerase beta and DNA ligase I in a multiprotein base excision repair complex from bovine testis
35. Reconstitution of DNA base excision-repair with purified human proteins: Interaction between DNA polymerase beta and the XRCC1 protein
36. Long patch base excision repair with purified human proteins. DNA ligase I as patch size mediator for DNA polymerases delta and epsilon
37. Reconstitution of proliferating cell nuclear antigen-dependent repair of apurinic/apyrimidinic sites with purified human proteins
38. Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA
39. Human thymine DNA glycosylase binds to apurinic sites in DNA but is displaced by human apurinic endonuclease 1
40. cDNA and deduced amino acid sequence of a mouse DNA repair enzyme (APEX nuclease) with significant homology to Escherichia coli exonuclease III
41. Rapid dissociation of human apurinic endonuclease (Apel) from incised DNA induced by magnesium
42. Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: Definition of a family of DNA repair enzymes
43. Characterization of a thermostable DNA glycosylase specific for U/G and T/G mismatches from the hyperthermophilic archaeon Pyrobaculum aerophilum
44. Post-replicative base excision repair in replication foci
45. Abasic site binding by the human apurinic endonuclease, Ape, and determination of the DNA contact sites