메뉴 건너뛰기




Volumn 34, Issue 6, 2014, Pages 905-912

Repression of SIRT1 promotes the differentiation of mouse induced pluripotent stem cells into neural stem cells

Author keywords

Differentiation; Induced pluripotent stem cell; microRNA 34a; Neural stem cell; SIRT1

Indexed keywords

MICRORNA 34A; RETINOIC ACID; SIRTUIN 1; MICRORNA;

EID: 84904358531     PISSN: 02724340     EISSN: 15736830     Source Type: Journal    
DOI: 10.1007/s10571-014-0071-8     Document Type: Article
Times cited : (24)

References (46)
  • 2
    • 79961058496 scopus 로고    scopus 로고
    • miR-34a regulates mouse neural stem cell differentiation
    • doi:10.1371/0021396
    • Aranha MM, Santos DM, Sola S, Steer CJ, Rodrigues CM (2011) miR-34a regulates mouse neural stem cell differentiation. PLoS ONE 6(8):e21396. doi:10.1371/0021396
    • (2011) PLoS ONE , vol.6 , Issue.8
    • Aranha, M.M.1    Santos, D.M.2    Sola, S.3    Steer, C.J.4    Rodrigues, C.M.5
  • 3
    • 0037160097 scopus 로고    scopus 로고
    • Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast Sir2 and human SIRT1
    • DOI 10.1074/jbc.M205670200
    • Bitterman KJ, Anderson RM, Cohen HY, Latorre-Esteves M, Sinclair DA (2002) Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1. J Biol Chem 277(47):45099-45107. doi:10.1074/20567 (Pubitemid 36159111)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.47 , pp. 45099-45107
    • Bitterman, K.J.1    Anderson, R.M.2    Cohen, H.Y.3    Latorre-Esteves, M.4    Sinclair, D.A.5
  • 4
    • 84859429591 scopus 로고    scopus 로고
    • Sirtuins in cognitive ageing and Alzheimer's disease
    • doi:10.1097/0b013e32835112c1
    • Braidy N, Jayasena T, Poljak A, Sachdev PS (2012) Sirtuins in cognitive ageing and Alzheimer's disease. Curr Opin Psychiatry 25(3):226-230. doi:10.1097/0b013e32835112c1
    • (2012) Curr Opin Psychiatry , vol.25 , Issue.3 , pp. 226-230
    • Braidy, N.1    Jayasena, T.2    Poljak, A.3    Sachdev, P.S.4
  • 7
    • 84880214905 scopus 로고    scopus 로고
    • Roles of SIRT1 in leukemogenesis
    • doi:10.1097/0b013e328360ab64
    • Chen W, Bhatia R (2013) Roles of SIRT1 in leukemogenesis. Curr Opin Hematol 20(4):308-313. doi:10.1097/0b013e328360ab64
    • (2013) Curr Opin Hematol , vol.20 , Issue.4 , pp. 308-313
    • Chen, W.1    Bhatia, R.2
  • 10
    • 84885144281 scopus 로고    scopus 로고
    • MicroRNAs and cell fate in cortical and retinal development
    • doi:10.3389/2013.00141
    • Cremisi F (2013) MicroRNAs and cell fate in cortical and retinal development. Front Cell Neurosci 7:141. doi:10.3389/2013.00141
    • (2013) Front Cell Neurosci , vol.7 , pp. 141
    • Cremisi, F.1
  • 11
    • 84874709843 scopus 로고    scopus 로고
    • SIRT1 and SIRT2: Emerging targets in neurodegeneration
    • doi:10.1002/ 201302451
    • Donmez G, Outeiro TF (2013) SIRT1 and SIRT2: emerging targets in neurodegeneration. EMBO Mol Med 5(3):344-352. doi:10.1002/ 201302451
    • (2013) EMBO Mol Med , vol.5 , Issue.3 , pp. 344-352
    • Donmez, G.1    Outeiro, T.F.2
  • 12
    • 77955417245 scopus 로고    scopus 로고
    • MicroRNA-34a regulation of endothelial senescence
    • doi:10.1016/2010.07.012
    • Ito T, Yagi S, Yamakuchi M (2010) MicroRNA-34a regulation of endothelial senescence. Biochem Biophys Res Commun 398(4):735-740. doi:10.1016/2010.07.012
    • (2010) Biochem Biophys Res Commun , vol.398 , Issue.4 , pp. 735-740
    • Ito, T.1    Yagi, S.2    Yamakuchi, M.3
  • 13
    • 0346435109 scopus 로고    scopus 로고
    • Mechanism of Nicotinamide Inhibition and Transglycosidation by Sir2 Histone/Protein Deacetylases
    • DOI 10.1074/jbc.M306552200
    • Jackson MD, Schmidt MT, Oppenheimer NJ, Denu JM (2003) Mechanism of nicotinamide inhibition and transglycosidation by Sir2 histone/protein deacetylases. J Biol Chem 278(51): 50985-50998. doi:10.1074/M306552200 (Pubitemid 38020332)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.51 , pp. 50985-50998
    • Jackson, M.D.1    Schmidt, M.T.2    Oppenheimer, N.J.3    Denu, J.M.4
  • 14
    • 84877027057 scopus 로고    scopus 로고
    • Survival and differentiation of transplanted neural stem cells derived from human induced pluripotent stem cells in a rat stroke model
    • doi:10.1016/2011.09.008
    • Jensen MB, Yan H, Krishnaney-Davison R, Al-Sawaf A, Zhang SC (2013) Survival and differentiation of transplanted neural stem cells derived from human induced pluripotent stem cells in a rat stroke model. J Stroke Cerebrovasc Dis 22(4):304-308. doi:10.1016/2011.09.008
    • (2013) J Stroke Cerebrovasc Dis , vol.22 , Issue.4 , pp. 304-308
    • Jensen, M.B.1    Yan, H.2    Krishnaney-Davison, R.3    Al-Sawaf, A.4    Zhang, S.C.5
  • 15
    • 67650810301 scopus 로고    scopus 로고
    • Regulation of stem cell pluripotency and differentiation involves a mutual regulatory circuit of the NANOG, OCT4, and SOX2 pluripotency transcription factors with polycomb repressive complexes and stem cell microRNAs
    • doi:10.1089/2009.0113
    • Kashyap V, Rezende NC, Scotland KB, Shaffer SM, Persson JL, Gudas LJ, Mongan NP (2009) Regulation of stem cell pluripotency and differentiation involves a mutual regulatory circuit of the NANOG, OCT4, and SOX2 pluripotency transcription factors with polycomb repressive complexes and stem cell microRNAs. Stem Cell Dev 18(7):1093-1108. doi:10.1089/2009.0113
    • (2009) Stem Cell Dev , vol.18 , Issue.7 , pp. 1093-1108
    • Kashyap, V.1    Rezende, N.C.2    Scotland, K.B.3    Shaffer, S.M.4    Persson, J.L.5    Gudas, L.J.6    Mongan, N.P.7
  • 16
    • 84873868477 scopus 로고    scopus 로고
    • Sirtuin 1 deacetylase: A key regulator of hepatic lipid metabolism
    • doi:10.1016/978-0-12-407766-9.00016
    • Kemper JK, Choi SE, Kim DH (2013) Sirtuin 1 deacetylase: a key regulator of hepatic lipid metabolism. Vitam Horm 91:385-404. doi:10.1016/978-0-12-407766- 9.00016
    • (2013) Vitam Horm , vol.91 , pp. 385-404
    • Kemper, J.K.1    Choi, S.E.2    Kim, D.H.3
  • 17
    • 85027938576 scopus 로고    scopus 로고
    • SIRT1, metabolism and cancer
    • doi:10.1097/0b013e32834d813b
    • Knight JR, Milner J (2012) SIRT1, metabolism and cancer. Curr Opin Oncol 24(1):68-75. doi:10.1097/0b013e32834d813b
    • (2012) Curr Opin Oncol , vol.24 , Issue.1 , pp. 68-75
    • Knight, J.R.1    Milner, J.2
  • 19
    • 77951210885 scopus 로고    scopus 로고
    • A pathway involving farnesoid X receptor and small heterodimer partner positively regulates hepatic sirtuin 1 levels via microRNA-34a inhibition
    • doi:10.1074/M109.094524
    • Lee J, Padhye A, Sharma A, Song G, Miao J, Mo YY, Wang L, Kemper JK (2010) A pathway involving farnesoid X receptor and small heterodimer partner positively regulates hepatic sirtuin 1 levels via microRNA-34a inhibition. J Biol Chem 285(17):12604-12611. doi:10.1074/M109.094524
    • (2010) J Biol Chem , vol.285 , Issue.17 , pp. 12604-12611
    • Lee, J.1    Padhye, A.2    Sharma, A.3    Song, G.4    Miao, J.5    Mo, Y.Y.6    Wang, L.7    Kemper, J.K.8
  • 20
    • 84866691285 scopus 로고    scopus 로고
    • Sirtuin 1 facilitates generation of induced pluripotent stem cells from mouse embryonic fibroblasts through the miR-34a and p53 pathways
    • doi:10.1371/0045633
    • Lee YL, Peng Q, Fong SW, Chen AC, Lee KF, Ng EH, Nagy A, Yeung WS (2012) Sirtuin 1 facilitates generation of induced pluripotent stem cells from mouse embryonic fibroblasts through the miR-34a and p53 pathways. PLoS ONE 7(9):e45633. doi:10.1371/0045633
    • (2012) PLoS ONE , vol.7 , Issue.9
    • Lee, Y.L.1    Peng, Q.2    Fong, S.W.3    Chen, A.C.4    Lee, K.F.5    Ng, E.H.6    Nagy, A.7    Yeung, W.S.8
  • 21
    • 43049084102 scopus 로고    scopus 로고
    • Enhanced efficiency of generating induced pluripotent stem (iPS) cells from human somatic cells by a combination of six transcription factors
    • DOI 10.1038/cr.2008.51, PII CR200851
    • Liao J, Wu Z, Wang Y, Cheng L, Cui C, Gao Y, Chen T, Rao L, Chen S, Jia N, Dai H, Xin S, Kang J, Pei G, Xiao L (2008) Enhanced efficiency of generating induced pluripotent stem (iPS) cells from human somatic cells by a combination of six transcription factors. Cell Res 18(5):600-603. doi:10.1038/2008.51 (Pubitemid 351630949)
    • (2008) Cell Research , vol.18 , Issue.5 , pp. 600-603
    • Liao, J.1    Wu, Z.2    Wang, Y.3    Cheng, L.4    Cui, C.5    Gao, Y.6    Chen, T.7    Rao, L.8    Chen, S.9    Jia, N.10    Dai, H.11    Xin, S.12    Kang, J.13    Pei, G.14    Xiao, L.15
  • 22
    • 84875872441 scopus 로고    scopus 로고
    • Insulin induces neurite outgrowth via SIRT1 in SH-SY5Y cells
    • doi:10.1016/2013.01.034
    • Liu Y, Yao Z, Zhang L, Zhu H, Deng W, Qin C (2013) Insulin induces neurite outgrowth via SIRT1 in SH-SY5Y cells. Neuroscience 238:371-380. doi:10.1016/2013.01.034
    • (2013) Neuroscience , vol.238 , pp. 371-380
    • Liu, Y.1    Yao, Z.2    Zhang, L.3    Zhu, H.4    Deng, W.5    Qin, C.6
  • 23
    • 84934444744 scopus 로고    scopus 로고
    • Regulation of stem cell populations by microRNAs
    • doi:10.1007/978-94-007-6621-1-18
    • Mathieu J, Ruohola-Baker H (2013) Regulation of stem cell populations by microRNAs. Adv Exp Med Biol 786:329-351. doi:10.1007/978-94-007-6621-1-18
    • (2013) Adv Exp Med Biol , vol.786 , pp. 329-351
    • Mathieu, J.1    Ruohola-Baker, H.2
  • 24
    • 84895817637 scopus 로고    scopus 로고
    • Sirtuins in neurodegenerative diseases: An update on potential mechanisms
    • (2013) doi:10.3389/00053
    • Min SW, Sohn PD, Cho SH, Swanson RA (2013) Gan L (2013) Sirtuins in neurodegenerative diseases: an update on potential mechanisms. Front Aging Neurosci 5:53. doi:10.3389/00053
    • (2013) Front Aging Neurosci , vol.5 , pp. 53
    • Min, S.W.1    Sohn, P.D.2    Cho, S.H.3    Swanson, R.A.4    Gan, L.5
  • 26
    • 84894251528 scopus 로고    scopus 로고
    • C/EBPa-mediated activation of micrornas 34a and 223 inhibits Lef1 expression to achieve efficient reprogramming into macrophages
    • doi:10.1128/01487-13
    • Rodriguez-Ubreva J, Ciudad L, van Oevelen C, Parra M, Graf T, Ballestar E (2014) C/EBPa-mediated activation of micrornas 34a and 223 inhibits Lef1 expression to achieve efficient reprogramming into macrophages. Mol Cell Biol 34(6):1145-1157. doi:10.1128/01487-13
    • (2014) Mol Cell Biol , vol.34 , Issue.6 , pp. 1145-1157
    • Rodriguez-Ubreva, J.1    Ciudad, L.2    Van Oevelen, C.3    Parra, M.4    Graf, T.5    Ballestar, E.6
  • 27
    • 84875068139 scopus 로고    scopus 로고
    • Pluripotent stem cell-derived somatic stem cells as tool to study the role of microRNAs in early human neural development
    • doi:10.2174/1566524011313050003
    • Roese-Koerner B, Stappert L, Koch P, Brustle O, Borghese L (2013) Pluripotent stem cell-derived somatic stem cells as tool to study the role of microRNAs in early human neural development. Curr Mol Med 13(5):707-722. doi:10.2174/1566524011313050003
    • (2013) Curr Mol Med , vol.13 , Issue.5 , pp. 707-722
    • Roese-Koerner, B.1    Stappert, L.2    Koch, P.3    Brustle, O.4    Borghese, L.5
  • 28
    • 84874815449 scopus 로고    scopus 로고
    • SIRT1 regulates the neurogenic potential of neural precursors in the adult subventricular zone and hippocampus
    • doi:10.1002/23199
    • Saharan S, Jhaveri DJ, Bartlett PF (2013) SIRT1 regulates the neurogenic potential of neural precursors in the adult subventricular zone and hippocampus. J Neurosci Res 91(5):642-659. doi:10.1002/23199
    • (2013) J Neurosci Res , vol.91 , Issue.5 , pp. 642-659
    • Saharan, S.1    Jhaveri, D.J.2    Bartlett, P.F.3
  • 29
    • 84891710615 scopus 로고    scopus 로고
    • Induced pluripotent stem cell-based studies of Parkinson's disease: Challenges and promises
    • doi:10.2174/187152731131200128
    • Sanchez-Danes A, Benzoni P, Memo M, Dell'era P, Raya A, Consiglio A (2013) Induced pluripotent stem cell-based studies of Parkinson's disease: challenges and promises. CNS Neurol Disord 12(8):1114-1127. doi:10.2174/ 187152731131200128
    • (2013) CNS Neurol Disord , vol.12 , Issue.8 , pp. 1114-1127
    • Sanchez-Danes, A.1    Benzoni, P.2    Memo, M.3    Dell'Era, P.4    Raya, A.5    Consiglio, A.6
  • 30
    • 0041571570 scopus 로고    scopus 로고
    • Sir2 regulation by nicotinamide results from switching between base exchange and deacetylation chemistry
    • DOI 10.1021/bi034959l
    • Sauve AA, Schramm VL (2003) Sir2 regulation by nicotinamide results from switching between base exchange and deacetylation chemistry. Biochemistry 42(31):9249-9256. doi:10.1021/034959l (Pubitemid 36959231)
    • (2003) Biochemistry , vol.42 , Issue.31 , pp. 9249-9256
    • Sauve, A.A.1    Schramm, V.L.2
  • 31
    • 84882901709 scopus 로고    scopus 로고
    • Process-based expansion and neural differentiation of human pluripotent stem cells for transplantation and disease modeling
    • doi:10.1002/23245
    • Stover AE, Brick DJ, Nethercott HE, Banuelos MG, Sun L, O'Dowd DK, Schwartz PH (2013) Process-based expansion and neural differentiation of human pluripotent stem cells for transplantation and disease modeling. J Neurosci Res 91(10):1247-1262. doi:10.1002/23245
    • (2013) J Neurosci Res , vol.91 , Issue.10 , pp. 1247-1262
    • Stover, A.E.1    Brick, D.J.2    Nethercott, H.E.3    Banuelos, M.G.4    Sun, L.5    O'Dowd, D.K.6    Schwartz, P.H.7
  • 32
    • 84883431348 scopus 로고    scopus 로고
    • Improved cell therapy protocols for Parkinson's disease based on differentiation efficiency and safety of hESC-, hiPSC-, and non-human primate iPSC-derived dopaminergic neurons
    • doi:10.1002/1415
    • Sundberg M, Bogetofte H, Lawson T, Jansson J, Smith G, Astradsson A, Moore M, Osborn T, Cooper O, Spealman R, Hallett P, Isacson O (2013) Improved cell therapy protocols for Parkinson's disease based on differentiation efficiency and safety of hESC-, hiPSC-, and non-human primate iPSC-derived dopaminergic neurons. Stem Cells 31(8):1548-1562. doi:10.1002/1415
    • (2013) Stem Cells , vol.31 , Issue.8 , pp. 1548-1562
    • Sundberg, M.1    Bogetofte, H.2    Lawson, T.3    Jansson, J.4    Smith, G.5    Astradsson, A.6    Moore, M.7    Osborn, T.8    Cooper, O.9    Spealman, R.10    Hallett, P.11    Isacson, O.12
  • 33
    • 84861567114 scopus 로고    scopus 로고
    • MicroRNA-34a regulates the longevity-associated protein SIRT1 in coronary artery disease: Effect of statins on SIRT1 and microRNA-34a expression
    • doi:10.1042/20110563
    • Tabuchi T, Satoh M, Itoh T, Nakamura M (2012) MicroRNA-34a regulates the longevity-associated protein SIRT1 in coronary artery disease: effect of statins on SIRT1 and microRNA-34a expression. Clin Sci 123(3):161-171. doi:10.1042/20110563
    • (2012) Clin Sci , vol.123 , Issue.3 , pp. 161-171
    • Tabuchi, T.1    Satoh, M.2    Itoh, T.3    Nakamura, M.4
  • 34
    • 0037474507 scopus 로고    scopus 로고
    • Human Sir2-related protein SIRT1 associates with the bHLH repressors HES1 and HEY2 and is involved in HES1- and HEY2-mediated transcriptional repression
    • doi:10. 1016/0006-291X(02)03020-6
    • Takata T, Ishikawa F (2003) Human Sir2-related protein SIRT1 associates with the bHLH repressors HES1 and HEY2 and is involved in HES1- and HEY2-mediated transcriptional repression. Biochem Biophys Res Commun 301(1):250-257. doi:10. 1016/0006-291X(02)03020-6
    • (2003) Biochem Biophys Res Commun , vol.301 , Issue.1 , pp. 250-257
    • Takata, T.1    Ishikawa, F.2
  • 35
    • 84861338375 scopus 로고    scopus 로고
    • Emerging beneficial roles of sirtuins in heart failure
    • doi:10.1007/s00395-012-0273-5
    • Tanno M, Kuno A, Horio Y, Miura T (2012) Emerging beneficial roles of sirtuins in heart failure. Basic Res Cardiol 107(4):273. doi:10.1007/s00395-012- 0273-5
    • (2012) Basic Res Cardiol , vol.107 , Issue.4 , pp. 273
    • Tanno, M.1    Kuno, A.2    Horio, Y.3    Miura, T.4
  • 36
    • 77956640572 scopus 로고    scopus 로고
    • miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells
    • doi:10.1096/09-152207
    • Tarantino C, Paolella G, Cozzuto L, Minopoli G, Pastore L, Parisi S, Russo T (2010) miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells. FASEB J 24(9): 3255-3263. doi:10.1096/09-152207
    • (2010) FASEB J , vol.24 , Issue.9 , pp. 3255-3263
    • Tarantino, C.1    Paolella, G.2    Cozzuto, L.3    Minopoli, G.4    Pastore, L.5    Parisi, S.6    Russo, T.7
  • 37
    • 84877154299 scopus 로고    scopus 로고
    • PET demonstrates functional recovery after transplantation of induced pluripotent stem cells in a rat model of cerebral ischemic injury
    • doi:10.2967/112.111112
    • Wang J, Chao F, Han F, Zhang G, Xi Q, Li J, Jiang H, Wang J, Yu G, Tian M, Zhang H (2013a) PET demonstrates functional recovery after transplantation of induced pluripotent stem cells in a rat model of cerebral ischemic injury. J Nucl Med 54(5):785-792. doi:10.2967/112.111112
    • (2013) J Nucl Med , vol.54 , Issue.5 , pp. 785-792
    • Wang, J.1    Chao, F.2    Han, F.3    Zhang, G.4    Xi, Q.5    Li, J.6    Jiang, H.7    Wang, J.8    Yu, G.9    Tian, M.10    Zhang, H.11
  • 39
    • 42649130264 scopus 로고    scopus 로고
    • Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease
    • doi:10.1073/0801677105
    • Wernig M, Zhao JP, Pruszak J, Hedlund E, Fu D, Soldner F, Broccoli V, Constantine-Paton M, Isacson O, Jaenisch R (2008) Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease. Proc Natl Acad Sci USA 105(15):5856-5861. doi:10.1073/0801677105
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.15 , pp. 5856-5861
    • Wernig, M.1    Zhao, J.P.2    Pruszak, J.3    Hedlund, E.4    Fu, D.5    Soldner, F.6    Broccoli, V.7    Constantine-Paton, M.8    Isacson, O.9    Jaenisch, R.10
  • 40
    • 84887925055 scopus 로고    scopus 로고
    • Road to future: IPSC clinical application in Parkinson's disease treatment
    • doi:10.2174/15665240113139990070
    • Xu L, Tan YY, Wu L, Wang LL, Li H, Ding JQ, Chen SD (2013) Road to future: iPSC clinical application in Parkinson's disease treatment. Curr Mol Med 13(9):1412-1418. doi:10.2174/15665240113139990070
    • (2013) Curr Mol Med , vol.13 , Issue.9 , pp. 1412-1418
    • Xu, L.1    Tan, Y.Y.2    Wu, L.3    Wang, L.L.4    Li, H.5    Ding, J.Q.6    Chen, S.D.7
  • 41
    • 84866314843 scopus 로고    scopus 로고
    • MicroRNA regulation of SIRT1
    • doi:10.3389/2012.00068
    • Yamakuchi M (2012) MicroRNA regulation of SIRT1. Front Physiol 3:68. doi:10.3389/2012.00068
    • (2012) Front Physiol , vol.3 , pp. 68
    • Yamakuchi, M.1
  • 42
    • 51649115553 scopus 로고    scopus 로고
    • miR-34a repression of SIRT1 regulates apoptosis
    • doi:10.1073/0801613105
    • Yamakuchi M, Ferlito M, Lowenstein CJ (2008) miR-34a repression of SIRT1 regulates apoptosis. Proc Natl Acad Sci USA 105(36):13421-13426. doi:10.1073/0801613105
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.36 , pp. 13421-13426
    • Yamakuchi, M.1    Ferlito, M.2    Lowenstein, C.J.3
  • 43
    • 84886904734 scopus 로고    scopus 로고
    • The emerging and diverse roles of sirtuins in cancer: A clinical perspective
    • doi:10.2147/37750
    • Yuan H, Su L, Chen WY (2013a) The emerging and diverse roles of sirtuins in cancer: a clinical perspective. Onco Targets Ther 6:1399-1416. doi:10.2147/37750
    • (2013) Onco Targets Ther , vol.6 , pp. 1399-1416
    • Yuan, H.1    Su, L.2    Chen, W.Y.3
  • 44
    • 84878895614 scopus 로고    scopus 로고
    • Human induced pluripotent stem cell-derived neural stem cells survive, migrate, differentiate, and improve neurological function in a rat model of middle cerebral artery occlusion
    • doi:10.1186/224
    • Yuan T, Liao W, Feng NH, Lou YL, Niu X, Zhang AJ, Wang Y, Deng ZF (2013b) Human induced pluripotent stem cell-derived neural stem cells survive, migrate, differentiate, and improve neurological function in a rat model of middle cerebral artery occlusion. Stem Cell Res Ther 4(3):73. doi:10.1186/224
    • (2013) Stem Cell Res Ther , vol.4 , Issue.3 , pp. 73
    • Yuan, T.1    Liao, W.2    Feng, N.H.3    Lou, Y.L.4    Niu, X.5    Zhang, A.J.6    Wang, Y.7    Deng, Z.F.8
  • 45
    • 78651358721 scopus 로고    scopus 로고
    • Inhibition of Sirt1 promotes neural progenitors toward motoneuron differentiation from human embryonic stem cells
    • doi:10.1016/2010.12.014
    • Zhang Y, Wang J, Chen G, Fan D, Deng M (2011) Inhibition of Sirt1 promotes neural progenitors toward motoneuron differentiation from human embryonic stem cells. Biochem Biophys Res Commun 404(2):610-614. doi:10.1016/2010.12.014
    • (2011) Biochem Biophys Res Commun , vol.404 , Issue.2 , pp. 610-614
    • Zhang, Y.1    Wang, J.2    Chen, G.3    Fan, D.4    Deng, M.5
  • 46
    • 84875831763 scopus 로고    scopus 로고
    • Regulation of TREM2 expression by an NFsmall ka, CyrillicB-sensitive miRNA-34a
    • doi:10.1097/0b013e32835fb6b0
    • Zhao Y, Bhattacharjee S, Jones BM, Dua P, Alexandrov PN, Hill JM, Lukiw WJ (2013) Regulation of TREM2 expression by an NFsmall ka, CyrillicB-sensitive miRNA-34a. NeuroReport 24(6): 318-323. doi:10.1097/0b013e32835fb6b0
    • (2013) NeuroReport , vol.24 , Issue.6 , pp. 318-323
    • Zhao, Y.1    Bhattacharjee, S.2    Jones, B.M.3    Dua, P.4    Alexandrov, P.N.5    Hill, J.M.6    Lukiw, W.J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.