Survival and differentiation of transplanted neural stem cells derived from human induced pluripotent stem cells in a rat stroke model

Journal of Stroke and Cerebrovascular Diseases

Volumn 22, Issue 4, 2013, Pages 304-308

  Jensen, Matthew B ^a   Yan, Hongmei ^a   Krishnaney Davison, Rajeev ^a   Al Sawaf, Abdullah ^a   Zhang, Su Chun ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Induced pluripotent stem cell; neural stem cell; stroke; transplantation

Indexed keywords

CYCLOSPORIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; BRAIN INFARCTION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CELL COUNT; CELL DIFFERENTIATION; CELL FATE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; GRAFT REJECTION; HEART STROKE VOLUME; HUMAN; HUMAN CELL; IN VITRO STUDY; NERVE CELL; NERVE REGENERATION; NEURAL STEM CELL; NEURAL STEM CELL TRANSPLANTATION; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; RAT; ANIMAL; ANIMAL BEHAVIOR; BRAIN; CELL LINE; CONVALESCENCE; DISEASE MODEL; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MOTOR ACTIVITY; PATHOLOGY; PATHOPHYSIOLOGY; TIME; TRANSPLANTATION; WISTAR RAT;

ANIMALS; BEHAVIOR, ANIMAL; BRAIN; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; DISEASE MODELS, ANIMAL; HUMANS; INDUCED PLURIPOTENT STEM CELLS; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MOTOR ACTIVITY; NERVE REGENERATION; NEURAL STEM CELLS; RATS; RATS, WISTAR; RECOVERY OF FUNCTION; TIME FACTORS;

EID: 84877027057     PISSN: 10523057     EISSN: 15328511     Source Type: Journal    
DOI: 10.1016/j.jstrokecerebrovasdis.2011.09.008     Document Type: Article

References (14)

1. D. Lloyd-Jones, R. Adams, and T. Brown Heart disease and stroke statistics - 2010 update: A report from the American Heart Association Circulation 121 2010 e46 e215
2. T. Bliss, R. Guzman, and M. Daadi Cell transplantation therapy for stroke Stroke 38 2007 817 826
3. G. Amabile, and A. Meissner Induced pluripotent stem cells: Current progress and potential for regenerative medicine Trends Mol Med 15 2009 59 68
4. J. Yu, K. Hu, and K. Smuga-Otto Human induced pluripotent stem cells free of vector and transgene sequences Science 324 2009 797 801
5. S. Zhang, M. Wernig, and I. Duncan In vitro differentiation of transplantable neural precursors from human embryonic stem cells Nat Biotechnol 19 2001 1129 1133
6. E. Longa, P. Weinstein, and S. Carlson Reversible middle cerebral artery occlusion without craniectomy in rats Stroke 20 1989 84 91
7. C. Borlongan, D. Cahill, and P. Sanberg Locomotor and passive avoidance deficits following occlusion of the middle cerebral artery Physiol Behav 58 1995 909 917
8. T. Schallert, S. Fleming, and J. Leasure CNS plasticity and assessment of forelimb sensorimotor outcome in unilateral rat models of stroke, cortical ablation, Parkinsonism and spinal cord injury Neuropharmacology 39 2000 777 787
9. C. Markgraf, E. Green, and B. Hurwitz Sensorimotor and cognitive consequences of middle cerebral artery occlusion in rats Brain Res 575 1992 238 246
10. Stem Cell Therapies as an Emerging Paradigm in Stroke (STEPS): Bridging basic and clinical science for cellular and neurogenic factor therapy in treating stroke Stroke 40 2009 510 515
11. D. Yang, Z.J. Zhang, and M. Oldenburg Human embryonic stem cell-derived dopaminergic neurons reverse functional deficit in Parkinsonian rats Stem Cells 26 2008 55 63
12. M.B. Jensen, A. Al Sawaf, and C. Zhang S- Human neural stem cell transplantation in animal stroke models: A systematic review Eur Neurol J 2011 (in press)
13. H. Kawai, T. Yamashita, and Y. Ohta Tridermal tumorigenesis of induced pluripotent stem cells transplanted in ischemic brain J Cereb Blood Flow Metab 30 2010 1487 1493
14. M. Jiang, L. Lv, and H. Ji Induction of pluripotent stem cells transplantation therapy for ischemic stroke Mol Cell Biochem 354 2011 67 75