TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential

Journal of Immunology

Volumn 193, Issue 2, 2014, Pages 571-579

  Bettini, Maria ^a,e   Blanchfield, Lori ^b   Castellaw, Ashley ^a   Zhang, Qianxia ^a,f   Nakayama, Maki ^c   Smeltzer, Matthew P ^a   Zhang, Hui ^a   Hogquist, Kristin A ^d   Evavold, Brian D ^b   Vignali, Dario A A ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF COLORADO DENVER   (United States)

^d UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^e BAYLOR COLLEGE OF MEDICINE   (United States)

^f UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DIABETES; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; DIABETES MELLITUS; DIABETOGENESIS; FEMALE; FLOW CYTOMETRY; IMMUNOLOGICAL TOLERANCE; IN VIVO STUDY; INSULITIS; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PANCREAS ISLET; PATHOGENICITY; PRIORITY JOURNAL; RECEPTOR AFFINITY;

ADOPTIVE TRANSFER; AMINO ACID SEQUENCE; ANIMALS; BINDING, COMPETITIVE; BONE MARROW TRANSPLANTATION; CD4-POSITIVE T-LYMPHOCYTES; CELL LINE; DIABETES MELLITUS, TYPE 1; EPITOPES, T-LYMPHOCYTE; FEMALE; FLOW CYTOMETRY; IMMUNE TOLERANCE; INSULIN; INTERLEUKIN-2; ISLETS OF LANGERHANS; MICE; MICE, 129 STRAIN; MICE, INBRED NOD; MICE, KNOCKOUT; MICE, SCID; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES;

EID: 84904253972     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1400043     Document Type: Article

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