Following the fate of one insulin-reactive CD4 T cell: Conversion into Teffs and Tregs in the periphery controls diabetes in NOD mice

Diabetes

Volumn 61, Issue 5, 2012, Pages 1169-1179

  Fousteri, Georgia ^a   Jasinski, Jean ^b,c   Dave, Amy ^a   Nakayama, Maki ^b   Pagni, Philippe ^a   Lambolez, Florence ^a   Juntti, Therese ^a   Sarikonda, Ghanashyam ^a   Cheng, Yang ^a   Croft, Michael ^a   Cheroutre, Hilde ^a   Eisenbarth, George ^b   Von Herrath, Matthias ^a  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c Partek Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INSULIN; INSULIN B CHAIN; INTERLEUKIN 10; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG;

ADOPTIVE TRANSFER; AGE DISTRIBUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN RECOGNITION; ARTICLE; BONE MARROW TRANSPLANTATION; CD4+ T LYMPHOCYTE; CELL FATE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIABETES MELLITUS; DIABETOGENESIS; EFFECTOR CELL; FEMALE; GENE MUTATION; GENETIC RECOMBINATION; IMMUNOLOGICAL TOLERANCE; IMMUNOPATHOGENESIS; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MALE; MOUSE; NONHUMAN; PENETRANCE; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; THYMUS; UPREGULATION;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; DIABETES MELLITUS; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; INSULIN; INTERFERON-GAMMA; INTERLEUKIN-10; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MICE; MICE, INBRED NOD; MICE, TRANSGENIC; MUTATION; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY;

EID: 84860548863     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db11-0671     Document Type: Article

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