Efficient and scalable expansion of human pluripotent stem cells under clinically compliant settings: A view in 2013

Annals of Biomedical Engineering

Volumn 42, Issue 7, 2014, Pages 1357-1372

  Wang, Ying ^a,b   Cheng, Linzhao ^b   Gerecht, Sharon ^a  

^a Johns Hopkins University   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cellular therapy; Clinical trials; Human pluripotent stem cells; Large scale expansion

Indexed keywords

STEM CELLS; SUBSTRATES; TISSUE ENGINEERING;

CELLULAR THERAPY; CLINICAL TRIAL; CURRENT GOOD MANUFACTURING PRACTICES; DEVELOPMENT AND CHALLENGES; GOOD CLINICAL PRACTICES; PLURIPOTENT STEM CELLS; REGENERATIVE MEDICINE; SYNTHESIZED SUBSTRATES;

EXPANSION;

BONE SIALOPROTEIN; BOVINE SERUM ALBUMIN; CELLULOSE; COLLAGEN TYPE 4; DEXTRAN; FIBROBLAST GROWTH FACTOR 2; FIBRONECTIN; GLYCOSAMINOGLYCAN; HUMAN SERUM ALBUMIN; INTEGRIN; LAMININ; MATRIGEL; MERCAPTOETHANOL; POLYMER; POLYSTYRENE; VITRONECTIN;

AMINO ACID SEQUENCE; ARTICLE; BIOPROCESS; BIOREACTOR; BIOREACTOR DESIGN; CELL AGGREGATION; CELL DIFFERENTIATION; CELL NUCLEUS TRANSPLANTATION; CELL VIABILITY; CLINICAL TRIAL (TOPIC); CONTAMINATION; CONTINUOUS CULTURE; CRYOPRESERVATION; CULTURE MEDIUM; ENVIRONMENTAL FACTOR; EXTRACELLULAR MATRIX; FEEDER CELL; GOOD MANUFACTURING PRACTICE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; HUMAN CELL; LARGE SCALE PRODUCTION; MEDICAL DEVICE; MICROCARRIER CULTURE; MONITORING; NONHUMAN; OLIGODENDROGLIA; PARKINSON DISEASE; PLURIPOTENT STEM CELL; PRACTICE GUIDELINE; PRIORITY JOURNAL; RETINA MACULA AGE RELATED DEGENERATION; SCALE UP; SOMATIC CELL; STARGARDT DISEASE; STEM CELL EXPANSION; STEM CELL RESEARCH; STEM CELL TRANSPLANTATION; STIRRED REACTOR; SUSPENSION CELL CULTURE; CULTURE TECHNIQUE; CYTOLOGY; DEVICES; PROCEDURES; REGENERATIVE MEDICINE;

BIOREACTORS; CELL CULTURE TECHNIQUES; HUMANS; PLURIPOTENT STEM CELLS; REGENERATIVE MEDICINE;

EID: 84904200925     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-013-0921-4     Document Type: Article

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