The fibronectin-binding integrins α5β1 and αvβ3 differentially modulate RhoA-GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis

Journal of Cell Biology

Volumn 159, Issue 6, 2002, Pages 1071-1086

  Danen, Erik H J ^a   Sonneveld, Petra ^a   Brakebusch, Cord ^b,c   Fässler, Reinhard ^b,c   Sonnenberg, Arnoud ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

^c MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

Cell matrix adhesion; Fibronectin; Integrin; Matrix assembly; Rho GTPase

Indexed keywords

BINDING PROTEIN; FIBRONECTIN; ISOPROTEIN; PROTEIN SUBUNIT; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 5; VITRONECTIN RECEPTOR;

ARTICLE; BINDING SITE; CELL ADHESION; CELL SPREADING; CHIMERA; CONTROLLED STUDY; EMBRYO; EXTRACELLULAR MATRIX; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; TISSUE GROWTH;

ACTINS; ANIMALS; CELL ADHESION; CELL SEPARATION; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FIBRIN; FIBRONECTINS; FLOW CYTOMETRY; FOCAL ADHESION KINASE 1; FOCAL ADHESION PROTEIN-TYROSINE KINASES; GENE EXPRESSION REGULATION; GTPASE-ACTIVATING PROTEINS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; GUANOSINE TRIPHOSPHATE; HUMANS; INTEGRIN ALPHA5BETA1; INTEGRIN ALPHAVBETA3; INTEGRINS; MICE; MICROFILAMENT PROTEINS; MICROSCOPY, FLUORESCENCE; NUCLEAR PROTEINS; PHENOTYPE; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-TYROSINE KINASES; PROTEINS; REPRESSOR PROTEINS; RETINOBLASTOMA-LIKE PROTEIN P130; RHOA GTP-BINDING PROTEIN; TIME FACTORS; TRANSFECTION; VINCULIN;

EID: 0037164867     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200205014     Document Type: Article

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