Efficient derivation and genetic modifications of human pluripotent stem cells on engineered human feeder cell lines

Stem Cells and Development

Volumn 21, Issue 12, 2012, Pages 2298-2311

  Zou, Chunlin ^a,b,c   Chou, Bin Kuan ^c,d   Dowey, Sarah N ^c,d   Tsang, Kitman ^c,d   Huang, Xiaosong ^c,d   Liu, Cyndi F ^c,d   Smith, Cory ^c   Yen, Jonathan ^c   Mali, Prashant ^c   Zhang, Yu Alex ^a,b   Cheng, Linzhao ^c,d   Ye, Zhaohui ^c,d  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^c JOHNS HOPKINS UNIVERSITY   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TELOMERASE REVERSE TRANSCRIPTASE; WNT3A PROTEIN;

ADULT; ARTICLE; CELL ENGINEERING; CELL EXPANSION; CELL IMMORTALIZATION; CELL LINE; CONTROLLED STUDY; DNA MODIFICATION; DNA TRANSPOSITION; EMBRYO; EMBRYONIC STEM CELL; FEEDER CELL; GENE EXPRESSION; GENE TARGETING; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; NONVIRAL GENE DELIVERY SYSTEM; PLURIPOTENT STEM CELL; PRIORITY JOURNAL;

ALKALINE PHOSPHATASE; ANIMALS; ANTIGENS, DIFFERENTIATION; BONE MARROW CELLS; CELL CULTURE TECHNIQUES; CELL PROLIFERATION; CELLS, CULTURED; COCULTURE TECHNIQUES; EMBRYONIC STEM CELLS; FEEDER CELLS; FEMALE; GENETIC ENGINEERING; GENETIC LOCI; HOMOLOGOUS RECOMBINATION; HUMANS; INDUCED PLURIPOTENT STEM CELLS; KARYOTYPE; MALE; MESENCHYMAL STROMAL CELLS; MICE; NEOPLASMS, EXPERIMENTAL; TELOMERASE; TERATOMA; TRANSDUCTION, GENETIC; WNT3A PROTEIN;

ANIMALIA;

EID: 84864710348     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2011.0688     Document Type: Article

References (48)

1. Cobo F, JM Navarro, MI Herrera, A Vivo, D Porcel, C Hernández, M Jurado, J Garćia-Castro and P Menendez. (2008). Electron microscopy reveals the presence of viruses in mouse embryonic fibroblasts but neither in human em-bryonic fibroblasts nor in human mesenchymal cells used for hESC maintenance: toward an implementation of microbi-ological quality assurance program in stem cell banks. Cloning Stem Cells 10:65-74.
2. Martin MJ, A Muotri, F Gage and A Varki. (2005). Human embryonic stem cells express an immunogenic nonhuman sialic acid. Nat Med 11:228-232.
3. Sun N, NJ Panetta, DM Gupta, KD Wilson, A Lee, F Jia, S Hu, AM Cherry, RC Robbins, MT Longaker and JC Wu. (2009). Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells. Proc Natl Acad Sci USA 106:15720-15725.
4. Sugii S, Y Kida, T Kawamura, J Suzuki, R Vassena, YQ Yin, MK Lutz, WT Berggren, JC Izpisúa Belmonte and RM Evans. (2010). Human and mouse adipose-derived cells support feeder-independent induction of pluripotent stem cells. Proc Natl Acad Sci USA 107:3558-3563.
5. Chen G, DR Gulbranson, Z Hou, JM Bolin, V Ruotti, MD Probasco, K Smuga-Otto, SE Howden, NR Diol, et al. (2011). Chemically defined conditions for human iPSC derivation and culture. Nat Methods 8:424-429.
6. Takahashi K, M Narita, M Yokura, T Ichisaka and S Ya-manaka. (2009). Human induced pluripotent stem cells on autologous feeders. PLoS One 4:e8067
7. Rodríguez-Pizà I, Y Richaud-Patin, R Vassena, F González, MJ Barrero, A Veiga, A Raya and JC Belmonte. (2010). Reprogramming of human fibroblasts to induced pluripo-tent stem cells under xeno-free conditions. Stem Cells 28: 36-44.
8. Zwaka T and J Thomson. (2003). Homologous recombina-tion in human embryonic stem cells. Nat Biotechnol 21:319-321.
9. Zou J, M Maeder, P Mali, S Pruett-Miller, S Thibodeau-Beganny, B Chou, G Chen, Z Ye, I Park, et al. (2009). Gene targeting of a disease-related gene in human induced plu-ripotent stem and embryonic stem cells. Cell Stem Cell 5:97-110.
10. Hockemeyer D, F Soldner, C Beard, Q Gao, M Mitalipova, R DeKelver, G Katibah, R Amora, E Boydston, et al. (2009). Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases. Nat Biotechnol 27:851-857
11. Zou J, CL Sweeney, BK Chou, U Choi, J Pan, H Wang, SN Dowey, L Cheng and HL Malech. (2011). Oxidase-deficient neutrophils from X-linked chronic granulomatous disease iPS cells: functional correction by zinc finger nuclease-me-diated safe harbor targeting. Blood 117:5561-5572.
12. Zou J, P Mali, X Huang, SN Dowey and L Cheng. (2011). Site-specific gene correction of a point mutation in human iPS cells derived from an adult patient with sickle cell dis-ease. Blood 118:4599-4608.
13. Yusa K, ST Rashid, H Strick-Marchand, I Varela, PQ Liu, DE Paschon, E Miranda, A Ordóñez, NR Hannan, et al. (2011). Targeted gene correction of α(1)-antitrypsin defi-ciency in induced pluripotent stem cells. Nature 478:391-394.
14. Lombardo A, P Genovese, CM Beausejour, S Colleoni, YL Lee, KA Kim, D Ando, FD Urnov, C Galli, et al. (2007). Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery. Nat Biotechnol 25:1298-1306.
15. Collin J and M Lako. (2011). Concise review: putting a finger on stem cell biology: zinc finger nuclease-driven targeted genetic editing in human pluripotent stem cells. Stem Cells 29:1021-1033.
16. Cheng L, H Hammond, Z Ye, X Zhan and G Dravid. (2003). Human adult marrow cells support prolonged expansion of human embryonic stem cells in culture. Stem Cells 21:131-142.
17. Dravid G, Z Ye, H Hammond, G Chen, A Pyle, P Donovan, X Yu and L Cheng. (2005). Defining the role of Wnt/beta-catenin signaling in the survival, proliferation, and self-renewal of human embryonic stem cells. Stem Cells 23:1489-1501.
18. Cai L, Z Ye, B Zhou, P Mali, C Zhou and L Cheng. (2007). Promoting human embryonic stem cell renewal or differentiation by modulating Wnt signal and culture con-ditions. Cell Res 17:62-72.
19. Cortes JL, L Sanchez, G Ligero, I Gutierrez-Aranda, P Cat-alina, C Elosua, PE Leone, R Montes, C Bueno, et al. (2009). Mesenchymal stem cells facilitate the derivation of human embryonic stem cells from cryopreserved poor-quality em-bryos. Hum Reprod 24:1844-1851.
20. Chou BK, P Mali, X Huang, Z Ye, SN Dowey, LM Resar, C Zou, YA Zhang, J Tong and L Cheng. (2011). Efficient hu-man iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures. Cell Res 21:518-529.
21. Mali P, BK Chou, J Yen, Z Ye, J Zou, S Dowey, RA Brodsky, JE Ohm, W Yu, et al. (2010). Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expres-sion of pluripotency-associated genes. Stem Cells 28:713-720.
22. Mali P, Z Ye, H Hommond, X Yu, J Lin, G Chen, J Zou and L Cheng. (2008). Improved efficiency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts. Stem Cells 26:1998-2005.
23. Ye Z, H Zhan, P Mali, S Dowey, D Williams, Y Jang, C Dang, J Spivak, A Moliterno and L Cheng. (2009). Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders. Blood 114:5473-5480.
24. Liu H, Z Ye, Y Kim, S Sharkis and Y Jang. (2010). Gen-eration of endoderm-derived human induced pluripotent stem cells from primary hepatocytes. Hepatology 51:1810-1819.
25. Choi SM, H Liu, P Chaudhari, Y Kim, L Cheng, J Feng, S Sharkis, Z Ye and YY Jang. (2011). Reprogramming of EBV-immortalized B-lymphocyte cell lines into induced pluripo-tent stem cells. Blood 118:1801-1805.
26. Yusa K, L Zhou, MA Li, A Bradley and NL Craig. (2011). A hyperactive piggyBac transposase for mammalian applica-tions. Proc Natl Acad Sci USA 108:1531-1536.
27. Pittenger MF, AM Mackay, SC Beck, RK Jaiswal, R Douglas, JD Mosca, MA Moorman, DW Simonetti, S Craig and DR Marshak. (1999). Multilineage potential of adult human mesenchymal stem cells. Science 284:143-147
28. Mali P, Z Ye, BK Chou, J Yen and L Cheng. (2010). An improved method for generating and identifying human induced pluripotent stem cells. Methods Mol Biol 636:191-205.
29. Chan EM, S Ratanasirintrawoot, IH Park, PD Manos, YH Loh, H Huo, JD Miller, O Hartung, J Rho, et al. (2009). Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells. Nat Biotechnol 27: 1033-1037.
30. Xue X, X Huang, S Nodland, L Mátés, L Ma, Z Izsvák, Z Ivics, T LeBien, R McIvor, J Wagner and X Zhou. (2009). Stable gene transfer and expression in cord blood-derived CD34+ hematopoietic stem and progenitor cells by a hy-peractive Sleeping Beauty transposon system. Blood 114: 1319-1330.
31. Lacoste A, F Berenshteyn and AH Brivanlou. (2009). An ef-ficient and reversible transposable system for gene delivery and lineage-specific differentiation in human embryonic stem cells. Cell Stem Cell 5:332-342.
32. Chen YT, K Furushima, PS Hou, AT Ku, JM Deng, CW Jang, H Fang, HP Adams, ML Kuo, et al. (2010). PiggyBac transposon-mediated, reversible gene transfer in human embry-onic stem cells. Stem Cells Dev 19:763-771.
33. Chen YT and A Bradley. (2000). A new positive/negative selectable marker, puDeltatk, for use in embryonic stem cells. Genesis 28:31-35.
34. Capecchi MR. (2005). Gene targeting in mice: functional analysis of the mammalian genome for the twenty-first century. Nat Rev Genet 6:507-512.
35. Ogata T, T Kozuka and T Kanda. (2003). Identification of an insulator in AAVS1, a preferred region for integration of adeno-associated virus DNA. J Virol 77:9000-9007
36. Smith JR, S Maguire, LA Davis, M Alexander, F Yang, S Chandran, C ffrench-Constant and RA Pedersen. (2008). Robust, persistent transgene expression in human embry-onic stem cells is achieved with AAVS1-targeted integration. Stem Cells 26:496-504.
37. DeKelver RC, VM Choi, EA Moehle, DE Paschon, D Hock-emeyer, SH Meijsing, Y Sancak, X Cui, EJ Steine, et al. (2010). Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome. Genome Res 20:1133-1142.
38. Richards M, CY Fong, WK Chan, PC Wong and A Bongso. (2002). Human feeders support prolonged undifferentiated growth of human inner cell masses and embryonic stem cells. Nat Biotechnol 20:933-936.
39. Amit M, V Margulets, H Segev, K Shariki, I Laevsky, R Coleman and J Itskovitz-Eldor. (2003). Human feeder layers for human embryonic stem cells. Biol Reprod 68: 2150-2156.
40. Hovatta O, M Mikkola, K Gertow, AM Strömberg, J In-zunza, J Hreinsson, B Rozell, E Blennow, M Andäng and L Ahrlund-Richter. (2003). A culture system using hu-man foreskin fibroblasts as feeder cells allows production of human embryonic stem cells. Hum Reprod 18:1404-1409.
41. Richards M, S Tan, CY Fong, A Biswas, WK Chan and A Bongso. (2003). Comparative evaluation of various human feeders for prolonged undifferentiated growth of human embryonic stem cells. Stem Cells 21:546-556.
42. Inzunza J, K Gertow, MA Strömberg, E Matilainen, E Blennow, H Skottman, S Wolbank, L Ahrlund-Richter and O Hovatta. (2005). Derivation of human embryonic stem cell lines in serum replacement medium using postnatal human fibroblasts as feeder cells. Stem Cells 23:544-549.
43. Stojkovic P, M Lako, R Stewart, S Przyborski, L Armstrong, J Evans, A Murdoch, T Strachan and M Stojkovic. (2005). An autogeneic feeder cell system that efficiently supports growth of undifferentiated human embryonic stem cells. Stem Cells 23:306-314.
44. Montes R, G Ligero, L Sanchez, P Catalina, T de la Cueva, A Nieto, GJ Melen, R Rubio, J Garćia-Castro, C Bueno and P Menendez. (2009). Feeder-free maintenance of hESCs in mesenchymal stem cell-conditioned media: distinct requirements for TGF-beta and IGF-II. Cell Res 19:698-709.
45. Sanchez L, I Gitierrez-Aranda, G Ligero, M Martin, V Ayl-lón, PJ Real, V Ramos-Mejia, C Bueno and P Menendez. (2011). Maintenance of hESCs in media conditioned by hu-man mesenchymal stem cells obviates the requirement of exogenous bFGF supplementation. Tissue Eng Part C Methods. Epub ahead of print; DOI: 10.1038/cr.2012.4.
46. Crook JM, TT Peura, L Kravets, AG Bosman, JJ Buzzard, R Horne, H Hentze, NR Dunn, R Zweigerdt, et al. (2007). The generation of six clinical-grade human embryonic stem cell lines. Cell Stem Cell 1:490-494.
47. Ramos V, AF Fernandez, V Ayllon, PJ Real, C Bueno, P Anderson, F Martin, MF Fraga and P Menendez. (2011). Maintenance of human embryonic stem cells in mesen-chymal stem cell-conditioned media augments hemato-poietic specification. Stem Cells Dev. Epub ahead of print; DOI: 10.1089/scd.2011.0400.
48. Broxmeyer HE, MR Lee, G Hangoc, S Cooper, N Prasain, YJ Kim, C Mallett, Z Ye, S Witting, et al. (2011). Hematopoietic stem/progenitor cells, generation of induced pluripotent stem cells, and isolation of endothelial progenitors from 21-to 23.5-year cryopreserved cord blood. Blood 117:4773-4777.