Recombinant vitronectin is a functionally defined substrate that supports human embryonic stem cell self-renewal via αVβ5 integrin

Stem Cells

Volumn 26, Issue 9, 2008, Pages 2257-2265

  Braam, Stefan R ^a,b   Zeinstra, Laura ^a   Litjens, Sandy ^a   Ward Van Oostwaard, Dorien ^a,b   Van Den Brink, Stieneke ^a   Van Laake, Linda ^a,c   Lebrin, Franck ^a   Kats, Peter ^c   Hochstenbach, Ron ^c   Passier, Robert ^a,b   Sonnenberg, Arnoud ^d   Mummery, Christine L ^a,b,c  

^a HUBRECHT INSTITUTE   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

Defined substrate; Extracellular matrix; Human embryonic stem cells; Integrins; Self renewal

Indexed keywords

BLOCKING ANTIBODY; COLLAGEN TYPE 4; ENTACTIN; FIBRONECTIN; INTEGRIN; LAMININ; MATRIGEL; RECOMBINANT PROTEIN; SCLEROPROTEIN; VITRONECTIN;

ARTICLE; CELL ADHESION; CELL GROWTH; CELL RENEWAL; EMBRYONIC STEM CELL; EXTRACELLULAR MATRIX; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ANIMALS; CELL ADHESION; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; COLLAGEN; CULTURE MEDIA; DRUG COMBINATIONS; EMBRYONIC STEM CELLS; EXTRACELLULAR MATRIX PROTEINS; HUMANS; LAMININ; MICE; PROTEOGLYCANS; RECEPTORS, VITRONECTIN; RECOMBINANT PROTEINS; VITRONECTIN;

EID: 55049123064     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2008-0291     Document Type: Article

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