Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures

Cell Research

Volumn 21, Issue 3, 2011, Pages 518-529

  Chou, Bin Kuan ^a,b   Mali, Prashant ^a,b   Huang, Xiaosong ^a,b   Ye, Zhaohui ^a,b   Dowey, Sarah N ^a,b   Resar, Linda M S ^b   Zou, Chunlin ^a,c   Zhang, Y Alex ^c   Tong, Jay ^d   Cheng, Linzhao ^a,b  

^a Institute for Cell Engineering   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c CAPITAL MEDICAL UNIVERSITY   (China)

^d AllCells LLC   (United States)

Author keywords

cord blood; DNA methylation; epigenetics; episomal vectors; iPS Cells; reprogramming; sickle cell disease

Indexed keywords

CARRIER PROTEIN; CD34 ANTIGEN; EBNA1BP2 PROTEIN, HUMAN;

ARTICLE; BLOOD CELL; CYTOLOGY; FETUS BLOOD; FIBROBLAST; GENE EXPRESSION PROFILING; GENETIC EPIGENESIS; GENETICS; HEMATOPOIETIC STEM CELL; HUMAN; METABOLISM; NUCLEAR REPROGRAMMING; PLASMID; PLURIPOTENT STEM CELL;

ANTIGENS, CD34; BLOOD CELLS; CARRIER PROTEINS; EPIGENESIS, GENETIC; FETAL BLOOD; FIBROBLASTS; GENE EXPRESSION PROFILING; HEMATOPOIETIC STEM CELLS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; NUCLEAR REPROGRAMMING; PLASMIDS;

IPS; SIMIAN VIRUS 40;

EID: 79952536226     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2011.12     Document Type: Article

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