메뉴 건너뛰기




Volumn 300, Issue 5, 2011, Pages

Immune and nonimmune components orchestrate the pathogenesis of inflamm atory bowel disease

Author keywords

Endothelium; Fibroblasts; IBD; Immunity

Indexed keywords

ADAPTIVE IMMUNITY; CELL FUNCTION; CELL INTERACTION; CELL TYPE; DENDRITIC CELL; ENDOTHELIUM CELL; ENTERITIS; HUMAN; IMMUNOPATHOGENESIS; INNATE IMMUNITY; INTESTINE EPITHELIUM CELL; MACROPHAGE; NONHUMAN; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW;

EID: 79955554997     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00472.2010     Document Type: Review
Times cited : (45)

References (58)
  • 1
    • 33846412586 scopus 로고    scopus 로고
    • + T cells and colonic subepithelial myofibroblasts: What are they doing in mucosal inflammation?
    • + T cells and colonic subepithelial myofibroblasts: what are they doing in mucosal inflammation? J Gastroenterol 42, Suppl 17: 29-33, 2007.
    • (2007) J Gastroenterol , vol.42 , Issue.SUPPL. 17 , pp. 29-33
    • Andoh, A.1    Ogawa, A.2    Bamba, S.3    Fujiyama, Y.4
  • 3
    • 12344290269 scopus 로고    scopus 로고
    • Patients with active inflammatory bowel disease lack immature peripheral blood plasmacytoid and myeloid dendritic cells
    • Baumgart DC, Metzke D, Schmitz J, Scheffold A, Sturm A, Wiedenmann B, Dignass AU. Patients with active inflammatory bowel disease lack immature peripheral blood plasmacytoid and myeloid dendritic cells. Gut 54: 228-236, 2005.
    • (2005) Gut , vol.54 , pp. 228-236
    • Baumgart, D.C.1    Metzke, D.2    Schmitz, J.3    Scheffold, A.4    Sturm, A.5    Wiedenmann, B.6    Dignass, A.U.7
  • 4
    • 0031004878 scopus 로고    scopus 로고
    • Enhanced leukocyte binding by intestinal microvascular endothelial cells in inflammatory bowel disease
    • Binion DG, West GA, Ina K, Ziats NP, Emancipator SN, Fiocchi C. Enhanced leukocyte binding by intestinal microvascular endothelial cells in inflammatory bowel disease. Gastroenterology 112: 1895-1907, 1997.
    • (1997) Gastroenterology , vol.112 , pp. 1895-1907
    • Binion, D.G.1    West, G.A.2    Ina, K.3    Ziats, N.P.4    Emancipator, S.N.5    Fiocchi, C.6
  • 5
    • 0032576359 scopus 로고    scopus 로고
    • Acquired increase in leucocyte binding by intestinal microvascular endothelium in inflammatory bowel disease
    • Binion DG, West GA, Volk EE, Drazba JA, Ziats NP, Petras RE, Fiocchi C. Acquired increase in leucocyte binding by intestinal microvascular endothelium in inflammatory bowel disease. Lancet 352: 1742-1746, 1998.
    • (1998) Lancet , vol.352 , pp. 1742-1746
    • Binion, D.G.1    West, G.A.2    Volk, E.E.3    Drazba, J.A.4    Ziats, N.P.5    Petras, R.E.6    Fiocchi, C.7
  • 7
    • 33644882738 scopus 로고    scopus 로고
    • Antigen targeting to MHC class II-enriched late endosomes in colonic epithelial cells: Trafficking of luminal antigens studied in vivo in Crohn's colitis patients
    • Buning J, Hundorfean G, Schmitz M, Zimmer KP, Strobel S, Gebert A, Ludwig D. Antigen targeting to MHC class II-enriched late endosomes in colonic epithelial cells: trafficking of luminal antigens studied in vivo in Crohn's colitis patients. FASEB J 20: 359-361, 2006.
    • (2006) FASEB J , vol.20 , pp. 359-361
    • Buning, J.1    Hundorfean, G.2    Schmitz, M.3    Zimmer, K.P.4    Strobel, S.5    Gebert, A.6    Ludwig, D.7
  • 8
    • 33845910419 scopus 로고    scopus 로고
    • Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagement
    • Chieppa M, Rescigno M, Huang AY, Germain RN. Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagement. J Exp Med 203: 2841-2852, 2006.
    • (2006) J Exp Med , vol.203 , pp. 2841-2852
    • Chieppa, M.1    Rescigno, M.2    Huang, A.Y.3    Germain, R.N.4
  • 10
    • 44349124113 scopus 로고    scopus 로고
    • The genetics and immunopathogenesis of inflammatory bowel disease
    • Cho JH. The genetics and immunopathogenesis of inflammatory bowel disease. Nat Rev Immunol 8: 458-466, 2008.
    • (2008) Nat Rev Immunol , vol.8 , pp. 458-466
    • Cho, J.H.1
  • 13
    • 53849097306 scopus 로고    scopus 로고
    • Nonimmune cells in inflammatory bowel disease: From victim to villain
    • Danese S. Nonimmune cells in inflammatory bowel disease: from victim to villain. Trends Immunol 29: 555-564, 2008.
    • (2008) Trends Immunol , vol.29 , pp. 555-564
    • Danese, S.1
  • 14
    • 79958227886 scopus 로고    scopus 로고
    • The role of the vascular and lymphatic endothelium in the pathogenesis of inflammatory bowel disease: Brothers in arms
    • In press. [EPub ahead of print]
    • Danese S. The role of the vascular and lymphatic endothelium in the pathogenesis of inflammatory bowel disease: brothers in arms. Gut. In press. [EPub ahead of print]
    • Gut
    • Danese, S.1
  • 15
    • 34248196591 scopus 로고    scopus 로고
    • Immune regulation by microvascular endothelial cells: Directing innate and adaptive immunity, coagulation, and inflammation
    • Danese S, Dejana E, Fiocchi C. Immune regulation by microvascular endothelial cells: directing innate and adaptive immunity, coagulation, and inflammation. J Immunol 178: 6017-6022, 2007.
    • (2007) J Immunol , vol.178 , pp. 6017-6022
    • Danese, S.1    Dejana, E.2    Fiocchi, C.3
  • 16
    • 44849118823 scopus 로고    scopus 로고
    • Multiple pathogenic roles of microvasculature in inflammatory bowel disease: A Jack of all trades
    • Deban L, Correale C, Vetrano S, Malesci A, Danese S. Multiple pathogenic roles of microvasculature in inflammatory bowel disease: a Jack of all trades. Am J Pathol 172: 1457-1466, 2008.
    • (2008) Am J Pathol , vol.172 , pp. 1457-1466
    • Deban, L.1    Correale, C.2    Vetrano, S.3    Malesci, A.4    Danese, S.5
  • 17
    • 0029586031 scopus 로고
    • Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD)
    • Duchmann R, Kaiser I, Hermann E, Mayet W, Ewe K, Meyer zum Buschenfelde KH. Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD). Clin Exp Immunol 102: 448-455, 1995.
    • (1995) Clin Exp Immunol , vol.102 , pp. 448-455
    • Duchmann, R.1    Kaiser, I.2    Hermann, E.3    Mayet, W.4    Ewe, K.5    Meyer Zum Buschenfelde, K.H.6
  • 19
    • 35848958662 scopus 로고    scopus 로고
    • New players in the cytokine orchestra of inflammatory bowel disease
    • Fantini MC, Monteleone G, MacDonald TT. New players in the cytokine orchestra of inflammatory bowel disease. Inflamm Bowel Dis 13: 1419-1423, 2007.
    • (2007) Inflamm Bowel Dis , vol.13 , pp. 1419-1423
    • Fantini, M.C.1    Monteleone, G.2    McDonald, T.T.3
  • 23
    • 0034614894 scopus 로고    scopus 로고
    • A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes
    • Huang FP, Platt N, Wykes M, Major JR, Powell TJ, Jenkins CD, Macpherson GG. A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes. J Exp Med 191: 435-444, 2000.
    • (2000) J Exp Med , vol.191 , pp. 435-444
    • Huang, F.P.1    Platt, N.2    Wykes, M.3    Major, J.R.4    Powell, T.J.5    Jenkins, C.D.6    McPherson, G.G.7
  • 25
    • 65749103989 scopus 로고    scopus 로고
    • Regulatory lymphocytes and intestinal inflammation
    • Izcue A, Coombes JL, Powrie F. Regulatory lymphocytes and intestinal inflammation. Annu Rev Immunol 27: 313-338, 2009.
    • (2009) Annu Rev Immunol , vol.27 , pp. 313-338
    • Izcue, A.1    Coombes, J.L.2    Powrie, F.3
  • 28
    • 27744437941 scopus 로고    scopus 로고
    • Abnormally differentiated subsets of intestinal macrophage play a key role in Th1-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria
    • Kamada N, Hisamatsu T, Okamoto S, Sato T, Matsuoka K, Arai K, Nakai T, Hasegawa A, Inoue N, Watanabe N, Akagawa KS, Hibi T. Abnormally differentiated subsets of intestinal macrophage play a key role in Th1-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria. J Immunol 175: 6900-6908, 2005.
    • (2005) J Immunol , vol.175 , pp. 6900-6908
    • Kamada, N.1    Hisamatsu, T.2    Okamoto, S.3    Sato, T.4    Matsuoka, K.5    Arai, K.6    Nakai, T.7    Hasegawa, A.8    Inoue, N.9    Watanabe, N.10    Akagawa, K.S.11    Hibi, T.12
  • 31
    • 54849421128 scopus 로고    scopus 로고
    • Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant
    • Kuballa P, Huett A, Rioux JD, Daly MJ, Xavier RJ. Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant. PLoS One 3: e3391, 2008.
    • (2008) PLoS One , vol.3
    • Kuballa, P.1    Huett, A.2    Rioux, J.D.3    Daly, M.J.4    Xavier, R.J.5
  • 33
    • 0034769413 scopus 로고    scopus 로고
    • Clustering of colonic lamina propria CD4(+) T cells to subepithelial dendritic cell aggregates precedes the development of colitis in a murine adoptive transfer model
    • Leithauser F, Trobonjaca Z, Moller P, Reimann J. Clustering of colonic lamina propria CD4(+) T cells to subepithelial dendritic cell aggregates precedes the development of colitis in a murine adoptive transfer model. Lab Invest 81: 1339-1349, 2001.
    • (2001) Lab Invest , vol.81 , pp. 1339-1349
    • Leithauser, F.1    Trobonjaca, Z.2    Moller, P.3    Reimann, J.4
  • 34
    • 1542618118 scopus 로고    scopus 로고
    • Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria
    • Macpherson AJ, Uhr T. Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria. Science 303: 1662-1665, 2004.
    • (2004) Science , vol.303 , pp. 1662-1665
    • McPherson, A.J.1    Uhr, T.2
  • 35
    • 0035554676 scopus 로고    scopus 로고
    • Regulatory T cells in the control of immune pathology
    • Maloy KJ, Powrie F. Regulatory T cells in the control of immune pathology. Nat Immunol 2: 816-822, 2001.
    • (2001) Nat Immunol , vol.2 , pp. 816-822
    • Maloy, K.J.1    Powrie, F.2
  • 36
    • 56249130033 scopus 로고    scopus 로고
    • Retinoic acid-dependent regulation of immune responses by dendritic cells and macrophages
    • Manicassamy S, Pulendran B. Retinoic acid-dependent regulation of immune responses by dendritic cells and macrophages. Semin Immunol 21: 22-27, 2009.
    • (2009) Semin Immunol , vol.21 , pp. 22-27
    • Manicassamy, S.1    Pulendran, B.2
  • 37
    • 0030995575 scopus 로고    scopus 로고
    • Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells
    • Monteleone G, Biancone L, Marasco R, Morrone G, Marasco O, Luzza F, Pallone F. Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells. Gastroenterology 112: 1169-1178, 1997.
    • (1997) Gastroenterology , vol.112 , pp. 1169-1178
    • Monteleone, G.1    Biancone, L.2    Marasco, R.3    Morrone, G.4    Marasco, O.5    Luzza, F.6    Pallone, F.7
  • 39
    • 33646487147 scopus 로고    scopus 로고
    • Th2 cytokines down-regulate TLR expression and function in human intestinal epithelial cells
    • Mueller T, Terada T, Rosenberg IM, Shibolet O, Podolsky DK. Th2 cytokines down-regulate TLR expression and function in human intestinal epithelial cells. J Immunol 176: 5805-5814, 2006.
    • (2006) J Immunol , vol.176 , pp. 5805-5814
    • Mueller, T.1    Terada, T.2    Rosenberg, I.M.3    Shibolet, O.4    Podolsky, D.K.5
  • 40
    • 0028861975 scopus 로고
    • Antibodies to interleukin 12 abrogate established experimental colitis in mice
    • Neurath MF, Fuss I, Kelsall BL, Stuber E, Strober W. Antibodies to interleukin 12 abrogate established experimental colitis in mice. J Exp Med 182: 1281-1290, 1995.
    • (1995) J Exp Med , vol.182 , pp. 1281-1290
    • Neurath, M.F.1    Fuss, I.2    Kelsall, B.L.3    Stuber, E.4    Strober, W.5
  • 43
    • 70349208627 scopus 로고    scopus 로고
    • Dendritic cells in intestinal homeostasis and disease
    • Rescigno M, Di Sabatino A. Dendritic cells in intestinal homeostasis and disease. J Clin Invest 119: 2441-2450, 2009.
    • (2009) J Clin Invest , vol.119 , pp. 2441-2450
    • Rescigno, M.1    di Sabatino, A.2
  • 46
    • 0030763573 scopus 로고    scopus 로고
    • Differential distribution of B7.1 (CD80) and B72 (CD86) costimulatory molecules on mucosal macrophage subsets in human inflammatory bowel disease (IBD)
    • Rugtveit J, Bakka A, Brandtzaeg P. Differential distribution of B7.1 (CD80) and B72 (CD86) costimulatory molecules on mucosal macrophage subsets in human inflammatory bowel disease (IBD). Clin Exp Immunol 110: 104-113, 1997.
    • (1997) Clin Exp Immunol , vol.110 , pp. 104-113
    • Rugtveit, J.1    Bakka, A.2    Brandtzaeg, P.3
  • 47
    • 2942668041 scopus 로고    scopus 로고
    • Lymphatic vasculature: Development, molecular regulation and role in tumor metastasis and inflammation
    • Saharinen P, Tammela T, Karkkainen MJ, Alitalo K. Lymphatic vasculature: development, molecular regulation and role in tumor metastasis and inflammation. Trends Immunol 25: 387-395, 2004.
    • (2004) Trends Immunol , vol.25 , pp. 387-395
    • Saharinen, P.1    Tammela, T.2    Karkkainen, M.J.3    Alitalo, K.4
  • 48
    • 23344446570 scopus 로고    scopus 로고
    • Intestinal macrophages: Unique effector cells of the innate immune system
    • Smith PD, Ochsenbauer-Jambor C, Smythies LE. Intestinal macrophages: unique effector cells of the innate immune system. Immunol Rev 206: 149-159, 2005.
    • (2005) Immunol Rev , vol.206 , pp. 149-159
    • Smith, P.D.1    Ochsenbauer-Jambor, C.2    Smythies, L.E.3
  • 51
    • 0036218221 scopus 로고    scopus 로고
    • The immunology of mucosal models of inflammation
    • Strober W, Fuss IJ, Blumberg RS. The immunology of mucosal models of inflammation. Annu Rev Immunol 20: 495-549, 2002.
    • (2002) Annu Rev Immunol , vol.20 , pp. 495-549
    • Strober, W.1    Fuss, I.J.2    Blumberg, R.S.3
  • 52
    • 7244251444 scopus 로고    scopus 로고
    • Divergent cell cycle kinetics underlie the distinct functional capacity of mucosal T cells in Crohn's disease and ulcerative colitis
    • Sturm A, Leite AZ, Danese S, Krivacic KA, West GA, Mohr S, Jacobberger JW, Fiocchi C. Divergent cell cycle kinetics underlie the distinct functional capacity of mucosal T cells in Crohn's disease and ulcerative colitis. Gut 53: 1624-1631, 2004.
    • (2004) Gut , vol.53 , pp. 1624-1631
    • Sturm, A.1    Leite, A.Z.2    Danese, S.3    Krivacic, K.A.4    West, G.A.5    Mohr, S.6    Jacobberger, J.W.7    Fiocchi, C.8
  • 53
    • 0033034365 scopus 로고    scopus 로고
    • Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils
    • Takeda K, Clausen BE, Kaisho T, Tsujimura T, Terada N, Forster I, Akira S. Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils. Immunity 10: 39-49, 1999.
    • (1999) Immunity , vol.10 , pp. 39-49
    • Takeda, K.1    Clausen, B.E.2    Kaisho, T.3    Tsujimura, T.4    Terada, N.5    Forster, I.6    Akira, S.7
  • 55
    • 38349133365 scopus 로고    scopus 로고
    • The forgotten role of lymphangitis in Crohn's disease
    • Van Kruiningen HJ, Colombel JF. The forgotten role of lymphangitis in Crohn's disease. Gut 57: 1-4, 2008.
    • (2008) Gut , vol.57 , pp. 1-4
    • van Kruiningen, H.J.1    Colombel, J.F.2
  • 58
    • 34547176642 scopus 로고    scopus 로고
    • Unravelling the pathogenesis of inflammatory bowel disease
    • Xavier RJ, Podolsky DK. Unravelling the pathogenesis of inflammatory bowel disease. Nature 448: 427-434, 2007.
    • (2007) Nature , vol.448 , pp. 427-434
    • Xavier, R.J.1    Podolsky, D.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.