Alterations at the peptidyl transferase centre of the ribosome induced by the synergistic action of the streptogramins dalfopristin and quinupristin

BMC Biology

Volumn 2, Issue , 2004, Pages

  Harms, Jörg M ^a   Schlünzen, Frank ^a,b   Fucini, Paola ^b   Bartels, Heike ^a   Yonath, Ada ^a,c  

^a MAX PLANCK UNIT FOR STRUCTURAL MOLECULAR BIOLOGY   (Germany)

^b MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^c WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORAMPHENICOL; CLINDAMYCIN; DALFOPRISTIN; DALFOPRISTIN PLUS QUINUPRISTIN; ERYTHROMYCIN; MACROLIDE; MIKAMYCIN B; PEPTIDYLTRANSFERASE; PUROMYCIN; QUINUPRISTIN; RIBOSOME RNA; STREPTOGRAMIN; TRANSFER RNA; ANTIINFECTIVE AGENT; RIBOSOME PROTEIN; RNA 23S; VIRGINIAMYCIN;

ANIMAL CELL; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERICIDAL ACTIVITY; BACTERIOSTASIS; BINDING SITE; BIOCHEMISTRY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DEINOCOCCUS RADIODURANS; DRUG BINDING; DRUG MECHANISM; DRUG POTENTIATION; DRUG STRUCTURE; DRUG TARGETING; GENE MUTATION; GENETIC CONSERVATION; NONHUMAN; PHENOTYPE; PROTEIN MODIFICATION; PROTEIN SYNTHESIS INHIBITION; RIBOSOME; RIBOSOME SUBUNIT; ANALOGS AND DERIVATIVES; CHEMISTRY; CRYSTALLIZATION; DEINOCOCCUS; DRUG EFFECTS; ENZYMOLOGY; METABOLISM;

ANTI-BACTERIAL AGENTS; BINDING SITES; CRYSTALLIZATION; DEINOCOCCUS; DRUG SYNERGISM; PEPTIDYL TRANSFERASES; RIBOSOMAL PROTEINS; RIBOSOMES; RNA, RIBOSOMAL, 23S; VIRGINIAMYCIN;

EID: 3242712966     PISSN: 17417007     EISSN: None     Source Type: Journal    
DOI: 10.1186/1741-7007-2-4     Document Type: Article

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