PARP-1 activation causes neuronal death in the hippocampal CA1 region by increasing the expression of Ca2+-permeable AMPA receptors

Neurobiology of Disease

Volumn 70, Issue , 2014, Pages 43-52

  Gerace, E ^a   Masi, A ^a   Resta, F ^a   Felici, R ^a   Landucci, E ^a   Mello, T ^b   Pellegrini Giampietro, D E ^a   Mannaioni, G ^a   Moroni, F ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Cell death; GluA1; Hippocampus; MNNG; Organotypic hippocampal slices; PARP

Indexed keywords

6 NITRO 7 SULFAMOYLBENZO[F]QUINOXALINE 2,3 DIONE; ADENOSINE DIPHOSPHATE RIBOSE; ADENOSINE TRIPHOSPHATE; AMPA RECEPTOR; CALCIUM PERMEABLE AMPA RECEPTOR; CASPASE 3; CASPASE 7; DIZOCILPINE; GLUA1 AMPA RECEPTOR SUBUNIT; GLUA2 AMPA RECEPTOR SUBUNIT; GLUTAMATE RECEPTOR; METHYLNITRONITROSOGUANIDINE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; TRANSIENT RECEPTOR POTENTIAL CHANNEL M2; UNCLASSIFIED DRUG; CALCIUM; CASPASE; GLUCOSE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARP1 PROTEIN, RAT; PARP2 PROTEIN, RAT; TRANSIENT RECEPTOR POTENTIAL CHANNEL M; TRPM2 PROTEIN, RAT; 1 NAPHTHYL ACETYL SPERMINE; APOPTOSIS INDUCING FACTOR; CALCIUM ION; GLUA2 AMPA SUBUNIT; GLUTAMATE AMPA RECEPTOR SUBUNIT; GLUTAMATE RECEPTOR ANTAGONIST; ION CHANNEL; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 2; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; ENZYME ACTIVATION; EXCITATORY POSTSYNAPTIC POTENTIAL; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA3 REGION; NERVE CELL NECROSIS; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; ANOXIA; ANTAGONISTS AND INHIBITORS; CELL DEATH; CHEMICALLY INDUCED; DEFICIENCY; DRUG EFFECTS; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PYRAMIDAL NERVE CELL; TISSUE CULTURE TECHNIQUE; WISTAR RAT; ANIMAL CELL; ANIMAL EXPERIMENT; CELL LOSS; CELL SURVIVAL; ELECTROPHYSIOLOGICAL PROCEDURES; ENZYME ACTIVITY; MEMBRANE PERMEABILITY; NERVE CELL PLASTICITY; PROTEIN EXPRESSION;

ANIMALS; ANOXIA; CA1 REGION, HIPPOCAMPAL; CA3 REGION, HIPPOCAMPAL; CALCIUM; CASPASES; CELL DEATH; GLUCOSE; NERVE DEGENERATION; POLY(ADP-RIBOSE) POLYMERASES; PYRAMIDAL CELLS; RATS, WISTAR; RECEPTORS, AMPA; RECEPTORS, N-METHYL-D-ASPARTATE; TISSUE CULTURE TECHNIQUES; TRPM CATION CHANNELS;

EID: 84903900890     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2014.05.023     Document Type: Article

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