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Volumn 3, Issue 9, 2012, Pages

AIF-mediated caspase-independent necroptosis requires ATM and DNA-PK-induced histone H2AX Ser139 phosphorylation

Author keywords

AIF; ATM; DNA PK; H2AX; Necroptosis

Indexed keywords

APOPTOSIS INDUCING FACTOR; ATM PROTEIN; CALPAIN; DNA DEPENDENT PROTEIN KINASE; HISTONE H2AX; METHYLNITRONITROSOGUANIDINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN BAX; PROTEIN BID; SERINE; STRESS ACTIVATED PROTEIN KINASE;

EID: 84867203819     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2012.120     Document Type: Article
Times cited : (81)

References (40)
  • 2
    • 78649901091 scopus 로고    scopus 로고
    • Alternative cell death mechanisms in development and beyond
    • Yuan J, Kroemer G. Alternative cell death mechanisms in development and beyond. Genes Dev 2010; 24: 2592-2602.
    • (2010) Genes Dev , vol.24 , pp. 2592-2602
    • Yuan, J.1    Kroemer, G.2
  • 5
    • 84862907788 scopus 로고    scopus 로고
    • Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase
    • Sun L, Wang H, Wang Z, He S, Chen S, Liao D et al. Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase. Cell 2012; 148: 213-227.
    • (2012) Cell , vol.148 , pp. 213-227
    • Sun, L.1    Wang, H.2    Wang, Z.3    He, S.4    Chen, S.5    Liao, D.6
  • 6
    • 84862909353 scopus 로고    scopus 로고
    • The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways
    • Wang Z, Jiang H, Chen S, Du F, Wang X. The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways. Cell 2012; 148: 228-243.
    • (2012) Cell , vol.148 , pp. 228-243
    • Wang, Z.1    Jiang, H.2    Chen, S.3    Du, F.4    Wang, X.5
  • 7
    • 79954520766 scopus 로고    scopus 로고
    • AIF-mediated caspaseindependent necroptosis: A new chance for targeted therapeutics
    • Delavallee L, Cabon L, Galan-Malo P, Lorenzo HK, Susin SA. AIF-mediated caspaseindependent necroptosis: a new chance for targeted therapeutics. IUBMB Life 2011; 63: 221-232.
    • (2011) IUBMB Life , vol.63 , pp. 221-232
    • Delavallee, L.1    Cabon, L.2    Galan-Malo, P.3    Lorenzo, H.K.4    Susin, S.A.5
  • 8
    • 33646827842 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation
    • DOI 10.1074/jbc.M508135200
    • Xu Y, Huang S, Liu ZG, Han J. Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation. J Biol Chem 2006; 281: 8788-8795. (Pubitemid 43847985)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.13 , pp. 8788-8795
    • Xu, Y.1    Huang, S.2    Liu, Z.-G.3    Han, J.4
  • 10
    • 34347344991 scopus 로고    scopus 로고
    • Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and bax is essential in apoptosis-inducing factor-mediated programmed necrosis
    • DOI 10.1128/MCB.02141-06
    • Moubarak RS, Yuste VJ, Artus C, Bouharrour A, Greer PA, Menissier-de Murcia J et al. Sequential activation of poly(ADP-Ribose) polymerase 1, Calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis. Mol Cell Biol 2007; 27: 4844-4862. (Pubitemid 47016136)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.13 , pp. 4844-4862
    • Moubarak, R.S.1    Yuste, V.J.2    Artus, C.3    Bouharrour, A.4    Greer, P.A.5    Menissier-de Murcia, J.6    Susin, S.A.7
  • 11
    • 77951975356 scopus 로고    scopus 로고
    • AIF promotes chromatinolysis and caspase-independent programmed necrosis by interacting with histone H2AX
    • Artus C, Boujrad H, Bouharrour A, Brunelle MN, Hoos S, Yuste VJ et al. AIF promotes chromatinolysis and caspase-independent programmed necrosis by interacting with histone H2AX. EMBO J 2010; 29: 1585-1599.
    • (2010) EMBO J , vol.29 , pp. 1585-1599
    • Artus, C.1    Boujrad, H.2    Bouharrour, A.3    Brunelle, M.N.4    Hoos, S.5    Yuste, V.J.6
  • 12
    • 77955727322 scopus 로고    scopus 로고
    • Histone H2AX: The missing link in AIF-mediated caspase-independent programmed necrosis
    • Baritaud M, Boujrad H, Lorenzo HK, Krantic S, Susin SA. Histone H2AX: The missing link in AIF-mediated caspase-independent programmed necrosis. Cell Cycle 2010; 9: 3166-3173.
    • (2010) Cell Cycle , vol.9 , pp. 3166-3173
    • Baritaud, M.1    Boujrad, H.2    Lorenzo, H.K.3    Krantic, S.4    Susin, S.A.5
  • 14
    • 3242880238 scopus 로고    scopus 로고
    • H2AX: The histone guardian of the genome
    • DOI 10.1016/j.dnarep.2004.03.024, PII S1568786404000837
    • Fernandez-Capetillo O, Lee A, Nussenzweig M, Nussenzweig A. H2AX: the histone guardian of the genome. DNA Repair (Amst) 2004; 3: 959-967. (Pubitemid 38997938)
    • (2004) DNA Repair , vol.3 , Issue.8-9 , pp. 959-967
    • Fernandez-Capetillo, O.1    Lee, A.2    Nussenzweig, M.3    Nussenzweig, A.4
  • 17
    • 0141740426 scopus 로고    scopus 로고
    • Focusing on foci: H2AX and the recruitment of DNA-damage response factors
    • Fernandez-Capetillo O, Celeste A, Nussenzweig A. Focusing on foci: H2AX and the recruitment of DNA-damage response factors. Cell Cycle 2003; 2: 426-427.
    • (2003) Cell Cycle , vol.2 , pp. 426-427
    • Fernandez-Capetillo, O.1    Celeste, A.2    Nussenzweig, A.3
  • 18
    • 0034737439 scopus 로고    scopus 로고
    • Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139
    • DOI 10.1074/jbc.275.13.9390
    • Rogakou EP, Nieves-Neira W, Boon C, Pommier Y, Bonner WM. Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139. J Biol Chem 2000; 275: 9390-9395. (Pubitemid 30185164)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.13 , pp. 9390-9395
    • Rogakou, E.P.1    Nieves-Neira, W.2    Boon, C.3    Pommier, Y.4    Bonner, W.M.5
  • 19
    • 33745487368 scopus 로고    scopus 로고
    • Cell apoptosis: Requirement of H2AX in DNA ladder formation, but not for the activation of caspase-3
    • DOI 10.1016/j.molcel.2006.05.023, PII S1097276506003388
    • Lu C, Zhu F, Cho YY, Tang F, Zykova T, Ma WY et al. Cell apoptosis: requirement of H2AX in DNA ladder formation, but not for the activation of caspase-3. Mol Cell 2006; 23: 121-32. (Pubitemid 43963445)
    • (2006) Molecular Cell , vol.23 , Issue.1 , pp. 121-132
    • Lu, C.1    Zhu, F.2    Cho, Y.-Y.3    Tang, F.4    Zykova, T.5    Ma, W.Y.6    Bode, A.M.7    Dong, Z.8
  • 20
    • 78649898777 scopus 로고    scopus 로고
    • MST1 promotes apoptosis through phosphorylation of histone H2AX
    • Wen W, Zhu F, Zhang J, Keum YS, Zykova T, Yao K et al. MST1 promotes apoptosis through phosphorylation of histone H2AX. J Biol Chem 2011; 285: 39108-39116.
    • (2011) J Biol Chem , vol.285 , pp. 39108-39116
    • Wen, W.1    Zhu, F.2    Zhang, J.3    Keum, Y.S.4    Zykova, T.5    Yao, K.6
  • 21
    • 0035834693 scopus 로고    scopus 로고
    • ATM phosphorylates histone H2AX in response to DNA double-strand breaks
    • Burma S, Chen BP, Murphy M, Kurimasa A, Chen DJ. ATM phosphorylates histone H2AX in response to DNA double-strand breaks. J Biol Chem 2001; 276: 42462-42467.
    • (2001) J Biol Chem , vol.276 , pp. 42462-42467
    • Burma, S.1    Chen, B.P.2    Murphy, M.3    Kurimasa, A.4    Chen, D.J.5
  • 23
    • 0035930537 scopus 로고    scopus 로고
    • Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress
    • Ward IM, Chen J. Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress. J Biol Chem 2001; 276: 47759-47762.
    • (2001) J Biol Chem , vol.276 , pp. 47759-47762
    • Ward, I.M.1    Chen, J.2
  • 24
    • 36849028692 scopus 로고    scopus 로고
    • AIF-mediated programmed necrosis: A highly regulated way to die
    • Boujrad H, Gubkina O, Robert N, Krantic S, Susin SA. AIF-mediated programmed necrosis: a highly regulated way to die. Cell Cycle 2007; 6: 2612-2619. (Pubitemid 350224042)
    • (2007) Cell Cycle , vol.6 , Issue.21 , pp. 2612-2619
    • Boujrad, H.1    Gubkina, O.2    Robert, N.3    Krantic, S.4    Susin, S.A.5
  • 25
    • 0032861343 scopus 로고    scopus 로고
    • Megabase chromatin domains involved in DNA double-strand breaks in vivo
    • Rogakou EP, Boon C, Redon C, Bonner WM. Megabase chromatin domains involved in DNA double-strand breaks in vivo. J Cell Biol 1999; 146: 905-916.
    • (1999) J Cell Biol , vol.146 , pp. 905-916
    • Rogakou, E.P.1    Boon, C.2    Redon, C.3    Bonner, W.M.4
  • 26
    • 20444391346 scopus 로고    scopus 로고
    • Chromatin in need of a fix: Phosphorylation of H2AX connects chromatin to DNA repair
    • DOI 10.1016/j.molcel.2005.05.008, PII S1097276505013146
    • Thiriet C, Hayes JJ. Chromatin in need of a fix: phosphorylation of H2AX connects chromatin to DNA repair. Mol Cell 2005; 18: 617-622. (Pubitemid 40804798)
    • (2005) Molecular Cell , vol.18 , Issue.6 , pp. 617-622
    • Thiriet, C.1    Hayes, J.J.2
  • 29
    • 79958865837 scopus 로고    scopus 로고
    • A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations
    • Toledo LI, Murga M, Zur R, Soria R, Rodriguez A, Martinez S et al. A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations. Nat Struct Mol Biol 2011; 18: 721-727.
    • (2011) Nat Struct Mol Biol , vol.18 , pp. 721-727
    • Toledo, L.I.1    Murga, M.2    Zur, R.3    Soria, R.4    Rodriguez, A.5    Martinez, S.6
  • 30
    • 0141619287 scopus 로고    scopus 로고
    • Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly(ADP-ribose) polymerase-1
    • Veuger SJ, Curtin NJ, Richardson CJ, Smith GC, Durkacz BW. Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly(ADP-ribose) polymerase-1. Cancer Res 2003; 63: 6008-6015. (Pubitemid 37187504)
    • (2003) Cancer Research , vol.63 , Issue.18 , pp. 6008-6015
    • Veuger, S.J.1    Curtin, N.J.2    Richardson, C.J.3    Smith, G.C.M.4    Durkacz, B.W.5
  • 32
    • 53149119164 scopus 로고    scopus 로고
    • Interaction between PARP-1 and ATR in mouse fibroblasts is blocked by PARP inhibition
    • Kedar PS, Stefanick DF, Horton JK, Wilson SH. Interaction between PARP-1 and ATR in mouse fibroblasts is blocked by PARP inhibition. DNA Repair (Amst) 2008; 7: 1787-1798.
    • (2008) DNA Repair (Amst) , vol.7 , pp. 1787-1798
    • Kedar, P.S.1    Stefanick, D.F.2    Horton, J.K.3    Wilson, S.H.4
  • 33
    • 0037472924 scopus 로고    scopus 로고
    • DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
    • DOI 10.1038/nature01368
    • Bakkenist CJ, Kastan MB. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 2003; 421: 499-506. (Pubitemid 36168436)
    • (2003) Nature , vol.421 , Issue.6922 , pp. 499-506
    • Bakkenist, C.J.1    Kastan, M.B.2
  • 35
    • 0034610814 scopus 로고    scopus 로고
    • The language of covalent histone modifications
    • DOI 10.1038/47412
    • Strahl BD, Allis CD. The language of covalent histone modifications. Nature 2000; 403: 41-45. (Pubitemid 30038513)
    • (2000) Nature , vol.403 , Issue.6765 , pp. 41-45
    • Strahl, B.D.1    Allis, C.D.2
  • 36
    • 58149476936 scopus 로고    scopus 로고
    • Death receptor-induced activation of the Chk2- and histone H2AX-associated DNA damage response pathways
    • Solier S, Sordet O, Kohn KW, Pommier Y. Death receptor-induced activation of the Chk2- and histone H2AX-associated DNA damage response pathways. Mol Cell Biol 2009; 29: 68-82.
    • (2009) Mol Cell Biol , vol.29 , pp. 68-82
    • Solier, S.1    Sordet, O.2    Kohn, K.W.3    Pommier, Y.4
  • 37
    • 0034700511 scopus 로고    scopus 로고
    • A role for Saccharomyces cerevisiae histone H2A in DNA repair
    • DOI 10.1038/35050000
    • Downs JA, Lowndes NF, Jackson SP. A role for saccharomyces cerevisiae histone H2A in DNA repair. Nature 2000; 408: 1001-1004. (Pubitemid 32101649)
    • (2000) Nature , vol.408 , Issue.6815 , pp. 1001-1004
    • Downs, J.A.1    Lowndes, N.F.2    Jackson, S.P.3
  • 39
    • 68249113593 scopus 로고    scopus 로고
    • Common mechanisms of PIKK regulation
    • Lovejoy CA, Cortez D. Common mechanisms of PIKK regulation. DNA Repair (Amst) 2009; 8: 1004-1008.
    • (2009) DNA Repair (Amst) , vol.8 , pp. 1004-1008
    • Lovejoy, C.A.1    Cortez, D.2
  • 40
    • 34447548569 scopus 로고    scopus 로고
    • Ataxia telangiectasia mutated (ATM) signaling network is modulated by a novel poly(ADP-ribose)-dependent pathway in the early response to DNA-damaging agents
    • DOI 10.1074/jbc.M608406200
    • Haince JF, Kozlov S, Dawson VL, Dawson TM, Hendzel MJ, Lavin MF et al. Ataxia telangiectasia mutated (ATM) signaling network is modulated by a novel poly(ADP-ribose)- dependent pathway in the early response to DNA-damaging agents. J Biol Chem 2007; 282: 16441-16453. (Pubitemid 47100334)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.22 , pp. 16441-16453
    • Haince, J.-F.1    Kozlov, S.2    Dawson, V.L.3    Dawson, T.M.4    Hendzel, M.J.5    Lavin, M.F.6    Poirier, G.G.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.