-
1
-
-
16844381981
-
Three-dimensional EM structure of the ectodomain of integrin αVβ3 in a complex with fibronectin
-
Adair, B.D., J.P. Xiong, C. Maddock, S.L. Goodman, M.A. Arnaout, and M. Yeager. 2005. Three-dimensional EM structure of the ectodomain of integrin αVβ3 in a complex with fibronectin. J. Cell Biol. 168:1109-1118. http://dx.doi.org/10.1083/jcb.200410068.
-
(2005)
J. Cell Biol.
, vol.168
, pp. 1109-1118
-
-
Adair, B.D.1
Xiong, J.P.2
Maddock, C.3
Goodman, S.L.4
Arnaout, M.A.5
Yeager, M.6
-
2
-
-
0027971378
-
The short amino acid sequence Pro-His-Ser-Arg-Asn in human fibronectin enhances cell-adhes/ive function
-
Aota, S., M. Nomizu, and K.M. Yamada. 1994. The short amino acid sequence Pro-His-Ser-Arg-Asn in human fibronectin enhances cell-adhesive function. J. Biol. Chem. 269:24756-24761.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 24756-24761
-
-
Aota, S.1
Nomizu, M.2
Yamada, K.M.3
-
3
-
-
0000389624
-
Theory of ionic hydration: Insights from molecular dynamics simulations and experiment
-
Babu, C.S., and C. Lim. 1999. Theory of ionic hydration: Insights from molecular dynamics simulations and experiment. J. Phys. Chem. B. 103:7958-7968. http://dx.doi.org/10.1021/jp9921912.
-
(1999)
J. Phys. Chem. B.
, vol.103
, pp. 7958-7968
-
-
Babu, C.S.1
Lim, C.2
-
4
-
-
84986512474
-
CHARMM: A program for macromolecular energy, minimization, and dynamics calculations
-
Brooks, B.R., R.E. Bruccoleri, B.D. Olafson, D.J. States, S. Swaminathan, and M. Karplus. 1983. CHARMM: A program for macromolecular energy, minimization, and dynamics calculations. J. Comput. Chem. 4:187-217. http://dx.doi.org/10.1002/jcc.540040211.
-
(1983)
J. Comput. Chem.
, vol.4
, pp. 187-217
-
-
Brooks, B.R.1
Bruccoleri, R.E.2
Olafson, B.D.3
States, D.J.4
Swaminathan, S.5
Karplus, M.6
-
5
-
-
0030740244
-
Molecular evolution of integrins: Genes encoding integrin beta subunits from a coral and a sponge
-
Brower, D.L., S.M. Brower, D.C. Hayward, and E.E. Ball. 1997. Molecular evolution of integrins: Genes encoding integrin beta subunits from a coral and a sponge. Proc. Natl. Acad. Sci. USA. 94:9182-9187. http://dx.doi.org/10.1073/pnas.94.17.9182.
-
(1997)
Proc. Natl. Acad. Sci. USA.
, vol.94
, pp. 9182-9187
-
-
Brower, D.L.1
Brower, S.M.2
Hayward, D.C.3
Ball, E.E.4
-
6
-
-
0033406615
-
Fine mapping of inhibitory anti-alpha5 monoclonal antibody epitopes that differentially affect integrin-ligand binding
-
Burrows, L., K. Clark, A.P. Mould, and M.J. Humphries. 1999. Fine mapping of inhibitory anti-alpha5 monoclonal antibody epitopes that differentially affect integrin-ligand binding. Biochem. J. 344:527-533. http://dx.doi.org/10.1042/0264-6021:3440527.
-
(1999)
Biochem. J.
, vol.344
, pp. 527-533
-
-
Burrows, L.1
Clark, K.2
Mould, A.P.3
Humphries, M.J.4
-
7
-
-
0141756175
-
Integrin avidity regulation: Are changes in affinity and conformation underemphasized? Curr
-
Carman, C.V., and T.A. Springer. 2003. Integrin avidity regulation: Are changes in affinity and conformation underemphasized? Curr. Opin. Cell Biol. 15:547-556. http://dx.doi.org/10.1016/j.ceb.2003.08.003.
-
(2003)
Opin. Cell Biol.
, vol.15
, pp. 547-556
-
-
Carman, C.V.1
Springer, T.A.2
-
8
-
-
0028134881
-
A general method for facilitating heterodimeric pairing between two proteins: Application to expression of alpha and beta T-cell receptor extracellular segments
-
Chang, H.C., Z. Bao, Y. Yao, A.G. Tse, E.C. Goyarts, M. Madsen, E. Kawasaki, P.P. Brauer, J.C. Sacchettini, S.G. Nathenson, et al. 1994. A general method for facilitating heterodimeric pairing between two proteins: Application to expression of alpha and beta T-cell receptor extracellular segments. Proc. Natl. Acad. Sci. USA. 91:11408-11412. http://dx.doi.org/10.1073/pnas.91.24.11408.
-
(1994)
Proc. Natl. Acad. Sci. USA.
, vol.91
, pp. 11408-11412
-
-
Chang, H.C.1
Bao, Z.2
Yao, Y.3
Tse, A.G.4
Goyarts, E.C.5
Madsen, M.6
Kawasaki, E.7
Brauer, P.P.8
Sacchettini, J.C.9
Nathenson, S.G.10
-
9
-
-
0344628802
-
Bistable regulation of integrin adhesiveness by a bipolar metal ion cluster
-
Chen, J., A. Salas, and T.A. Springer. 2003. Bistable regulation of integrin adhesiveness by a bipolar metal ion cluster. Nat. Struct. Biol. 10:995-1001. http://dx.doi.org/10.1038/nsb1011.
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 995-1001
-
-
Chen, J.1
Salas, A.2
Springer, T.A.3
-
10
-
-
13144250209
-
Solution structure and dynamics of linked cell attachment modules of mouse fibronectin containing the RGD and synergy regions: Comparison with the human fibronectin crystal structure
-
Copié, V., Y. Tomita, S.K. Akiyama, S. Aota, K.M. Yamada, R.M. Venable, R.W. Pastor, S. Krueger, and D.A. Torchia. 1998. Solution structure and dynamics of linked cell attachment modules of mouse fibronectin containing the RGD and synergy regions: Comparison with the human fibronectin crystal structure. J. Mol. Biol. 277:663-682. http://dx.doi.org/10.1006/jmbi.1998.1616.
-
(1998)
J. Mol. Biol.
, vol.277
, pp. 663-682
-
-
Copié, V.1
Tomita, Y.2
Akiyama, S.K.3
Aota, S.4
Yamada, K.M.5
Venable, R.M.6
Pastor, R.W.7
Krueger, S.8
Torchia, D.A.9
-
11
-
-
13244281317
-
Coot: Model-building tools for molecular graphics
-
Emsley, P., and K. Cowtan. 2004. Coot: Model-building tools for molecular graphics. Acta Crystallogr. D Biol. Crystallogr. 60:2126-2132. http:// dx.doi.org/10.1107/S0907444904019158.
-
(2004)
Acta Crystallogr. D Biol. Crystallogr.
, vol.60
, pp. 2126-2132
-
-
Emsley, P.1
Cowtan, K.2
-
12
-
-
0034617222
-
Molecular basis of ligand recognition by integrin alpha5beta 1 II. Specificity of arg-gly-Asp binding is determined by Trp157 OF THE alpha subunit
-
Humphries, J.D., J.A. Askari, X.P. Zhang, Y. Takada, M.J. Humphries, and A.P. Mould. 2000. Molecular basis of ligand recognition by integrin alpha5beta 1. II. Specificity of arg-gly-Asp binding is determined by Trp157 OF THE alpha subunit. J. Biol. Chem. 275:20337-20345. http://dx.doi.org/10.1074/jbc.M000568200.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 20337-20345
-
-
Humphries, J.D.1
Askari, J.A.2
Zhang, X.P.3
Takada, Y.4
Humphries, M.J.5
Mould, A.P.6
-
13
-
-
0033858742
-
Integrin structure
-
Humphries, M.J. 2000. Integrin structure. Biochem. Soc. Trans. 28:311-339. http://dx.doi.org/10.1042/0300-5127:0280311.
-
(2000)
Biochem. Soc. Trans.
, vol.28
, pp. 311-339
-
-
Humphries, M.J.1
-
14
-
-
0037145037
-
Integrins: Bidirectional, allosteric signaling machines
-
Hynes, R.O. 2002. Integrins: Bidirectional, allosteric signaling machines. Cell. 110:673-687. http://dx.doi.org/10.1016/S0092-8674(02)00971-6.
-
(2002)
Cell
, vol.110
, pp. 673-687
-
-
Hynes, R.O.1
-
15
-
-
0034710157
-
The evolution of cell adhesion
-
Hynes, R.O., and Q. Zhao. 2000. The evolution of cell adhesion. J. Cell Biol. 150:F89-F96. http://dx.doi.org/10.1083/jcb.150.2.F89.
-
(2000)
J. Cell Biol.
, vol.150
-
-
Hynes, R.O.1
Zhao, Q.2
-
16
-
-
0035249196
-
Generalized solvent boundary potential for computer simulations
-
Im, W., S. Berneche, and B. Roux. 2001. Generalized solvent boundary potential for computer simulations. J. Chem. Phys. 114:2924-2937. http://dx.doi.org/10.1063/1.1336570.
-
(2001)
J. Chem. Phys.
, vol.114
, pp. 2924-2937
-
-
Im, W.1
Berneche, S.2
Roux, B.3
-
17
-
-
33845922350
-
N-glycosylation of the beta-propeller domain of the integrin alpha5 subunit is essential for alpha5beta1 heterodimerization, expression on the cell surface, and its biological function
-
Isaji, T., Y. Sato, Y. Zhao, E. Miyoshi, Y. Wada, N. Taniguchi, and J. Gu. 2006. N-glycosylation of the beta-propeller domain of the integrin alpha5 subunit is essential for alpha5beta1 heterodimerization, expression on the cell surface, and its biological function. J. Biol. Chem. 281:33258-33267. http://dx.doi.org/10.1074/jbc.M607771200.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 33258-33267
-
-
Isaji, T.1
Sato, Y.2
Zhao, Y.3
Miyoshi, E.4
Wada, Y.5
Taniguchi, N.6
Gu, J.7
-
18
-
-
66449096361
-
N-glycosylation of the I-like domain of beta1 integrin is essential for beta1 integrin expression and biological function: Identification of the minimal N-glycosylation requirement for alpha5beta1
-
Isaji, T., Y. Sato, T. Fukuda, and J. Gu. 2009. N-glycosylation of the I-like domain of beta1 integrin is essential for beta1 integrin expression and biological function: Identification of the minimal N-glycosylation requirement for alpha5beta1. J. Biol. Chem. 284:12207-12216. http://dx.doi.org/10.1074/jbc.M807920200.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 12207-12216
-
-
Isaji, T.1
Sato, Y.2
Fukuda, T.3
Gu, J.4
-
19
-
-
0004016501
-
Comparison of simple potential functions for simulating liquid water
-
Jorgensen, W.L., J. Chandrasekhar, J.D. Madura, R.W. Impey, and M.L. Klein. 1983. Comparison of simple potential functions for simulating liquid water. J. Chem. Phys. 79:926-935. http://dx.doi.org/10.1063/1.445869.
-
(1983)
J. Chem. Phys.
, vol.79
, pp. 926-935
-
-
Jorgensen, W.L.1
Chandrasekhar, J.2
Madura, J.D.3
Impey, R.W.4
Klein, M.L.5
-
20
-
-
83355174046
-
Structure of collagen receptor integrin α(1)I domain carrying the activating mutation E317A
-
Lahti, M., E. Bligt, H. Niskanen, V. Parkash, A.M. Brandt, J. Jokinen, P. Patrikainen, J. Käpylä, J. Heino, and T.A. Salminen. 2011. Structure of collagen receptor integrin α(1)I domain carrying the activating mutation E317A. J. Biol. Chem. 286:43343-43351. http://dx.doi.org/10.1074/jbc.M111.261909.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 43343-43351
-
-
Lahti, M.1
Bligt, E.2
Niskanen, H.3
Parkash, V.4
Brandt, A.M.5
Jokinen, J.6
Patrikainen, P.7
Käpylä, J.8
Heino, J.9
Salminen, T.A.10
-
21
-
-
0030050396
-
2.0 A crystal structure of a four-domain segment of human fibronectin encompassing the RGD loop and synergy region
-
Leahy, D.J., I. Aukhil, and H.P. Erickson. 1996. 2.0 A crystal structure of a four-domain segment of human fibronectin encompassing the RGD loop and synergy region. Cell. 84:155-164. http://dx.doi.org/10.1016/S0092-8674(00)81002-8.
-
(1996)
Cell
, vol.84
, pp. 155-164
-
-
Leahy, D.J.1
Aukhil, I.2
Erickson, H.P.3
-
22
-
-
0037441653
-
Structure validation by Cα geometry: Φ ψ and Cβ deviation. Proteins
-
Lovell, S.C., I.W. Davis, W.B. Arendall III, P.I. de Bakker, J.M. Word, M.G. Prisant, J.S. Richardson, and D.C. Richardson. 2003. Structure validation by Cα geometry: Φ,ψ and Cβ deviation. Proteins. 50:437-450. http://dx.doi.org/10.1002/prot.10286.
-
(2003)
, vol.50
, pp. 437-450
-
-
Lovell, S.C.1
Davis, I.W.2
Arendall III, W.B.3
de Bakker, P.I.4
Word, J.M.5
Prisant, M.G.6
Richardson, J.S.7
Richardson, D.C.8
-
23
-
-
33748306120
-
Integrin structures and conformational signaling
-
Luo, B.H., and T.A. Springer. 2006. Integrin structures and conformational signaling. Curr. Opin. Cell Biol. 18:579-586. http://dx.doi.org/10.1016/ j.ceb.2006.08.005.
-
(2006)
Curr. Opin. Cell Biol.
, vol.18
, pp. 579-586
-
-
Luo, B.H.1
Springer, T.A.2
-
24
-
-
3042602113
-
Allosteric beta1 integrin antibodies that stabilize the low affinity state by preventing the swing-out of the hybrid domain
-
Luo, B.H., K. Strokovich, T. Walz, T.A. Springer, and J. Takagi. 2004. Allosteric beta1 integrin antibodies that stabilize the low affinity state by preventing the swing-out of the hybrid domain. J. Biol. Chem. 279:27466-27471. http://dx.doi.org/10.1074/jbc.M404354200.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 27466-27471
-
-
Luo, B.H.1
Strokovich, K.2
Walz, T.3
Springer, T.A.4
Takagi, J.5
-
25
-
-
0041784950
-
All-atom empirical potential for molecular modeling and dynamics studies of proteins
-
MacKerell, A.D. Jr., D. Bashford, M. Bellott, R.L. Dunbrack Jr., J.D. Evanseck, M.J. Field, S. Fischer, J. Gao, H. Guo, S. Ha, et al. 1998. All-atom empirical potential for molecular modeling and dynamics studies of proteins. J. Phys. Chem. B. 102:3586-3616. http://dx.doi.org/10.1021/jp973084f.
-
(1998)
J. Phys. Chem. B.
, vol.102
, pp. 3586-3616
-
-
MacKerell Jr., A.D.1
Bashford, D.2
Bellott, M.3
Dunbrack Jr., R.L.4
Evanseck, J.D.5
Field, M.J.6
Fischer, S.7
Gao, J.8
Guo, H.9
Ha, S.10
-
26
-
-
1642576012
-
Improved treatment of the protein backbone in empirical force fields
-
MacKerell, A.D. Jr., M. Feig, and C.L. Brooks III. 2004. Improved treatment of the protein backbone in empirical force fields. J. Am. Chem. Soc. 126:698-699. http://dx.doi.org/10.1021/ja036959e.
-
(2004)
J. Am. Chem. Soc.
, vol.126
, pp. 698-699
-
-
MacKerell Jr., A.D.1
Feig, M.2
Brooks III, C.L.3
-
27
-
-
0030798854
-
Defining the topology of integrin alpha5beta1-fibronectin interactions using inhibitory anti-alpha5 and anti-beta1 monoclonal antibodies
-
Mould, A.P., J.A. Askari, S. Aota, K.M. Yamada, A. Irie, Y. Takada, H.J. Mardon, and M.J. Humphries. 1997. Defining the topology of integrin alpha5beta1-fibronectin interactions using inhibitory anti-alpha5 and anti-beta1 monoclonal antibodies. Evidence that the synergy sequence of fibronectin is recognized by the amino-terminal repeats of the alpha5 subunit. J. Biol. Chem. 272:17283-17292. http://dx.doi.org/10.1074/jbc.272.28.17283.
-
(1997)
Evidence that the synergy sequence of fibronectin is recognized by the amino-terminal repeats of the alpha5 subunit. J. Biol. Chem.
, vol.272
, pp. 17283-17292
-
-
Mould, A.P.1
Askari, J.A.2
Aota, S.3
Yamada, K.M.4
Irie, A.5
Takada, Y.6
Mardon, H.J.7
Humphries, M.J.8
-
28
-
-
0037205483
-
Integrin activation involves a conformational change in the alpha 1 helix of the beta subunit A-domain
-
Mould, A.P., J.A. Askari, S. Barton, A.D. Kline, P.A. McEwan, S.E. Craig, and M.J. Humphries. 2002. Integrin activation involves a conformational change in the alpha 1 helix of the beta subunit A-domain. J. Biol. Chem. 277:19800-19805. http://dx.doi.org/10.1074/jbc.M201571200.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 19800-19805
-
-
Mould, A.P.1
Askari, J.A.2
Barton, S.3
Kline, A.D.4
McEwan, P.A.5
Craig, S.E.6
Humphries, M.J.7
-
29
-
-
0347695986
-
Role of ADMIDAS cation-binding site in ligand recognition by integrin alpha 5 beta 1
-
Mould, A.P., S.J. Barton, J.A. Askari, S.E. Craig, and M.J. Humphries. 2003a. Role of ADMIDAS cation-binding site in ligand recognition by integrin alpha 5 beta 1. J. Biol. Chem. 278:51622-51629. http://dx.doi.org/10.1074/jbc.M306655200.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 51622-51629
-
-
Mould, A.P.1
Barton, S.J.2
Askari, J.A.3
Craig, S.E.4
Humphries, M.J.5
-
30
-
-
0141960077
-
Structure of an integrin-ligand complex deduced from solution x-ray scattering and site-directed mutagenesis
-
Mould, A.P., E.J. Symonds, P.A. Buckley, J.G. Grossmann, P.A. McEwan, S.J. Barton, J.A. Askari, S.E. Craig, J. Bella, and M.J. Humphries. 2003b. Structure of an integrin-ligand complex deduced from solution x-ray scattering and site-directed mutagenesis. J. Biol. Chem. 278:39993-39999. http://dx.doi.org/10.1074/jbc.M304627200.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 39993-39999
-
-
Mould, A.P.1
Symonds, E.J.2
Buckley, P.A.3
Grossmann, J.G.4
McEwan, P.A.5
Barton, S.J.6
Askari, J.A.7
Craig, S.E.8
Bella, J.9
Humphries, M.J.10
-
31
-
-
0030924992
-
Refinement of macromolecular structures by the maximum-likelihood method
-
Murshudov, G.N., A.A. Vagin, and E.J. Dodson. 1997. Refinement of macromolecular structures by the maximum-likelihood method. Acta Crystallogr. D Biol. Crystallogr. 53:240-255. http://dx.doi.org/10.1107/S0907444996012255.
-
(1997)
Acta Crystallogr. D Biol. Crystallogr.
, vol.53
, pp. 240-255
-
-
Murshudov, G.N.1
Vagin, A.A.2
Dodson, E.J.3
-
32
-
-
0024292679
-
Site-directed mutagenesis of the cell-binding domain of human fibronectin: Separable, synergistic sites mediate adhesive function
-
Obara, M., M.S. Kang, and K.M. Yamada. 1988. Site-directed mutagenesis of the cell-binding domain of human fibronectin: Separable, synergistic sites mediate adhesive function. Cell. 53:649-657. http://dx.doi.org/10.1016/0092-8674(88)90580-6.
-
(1988)
Cell
, vol.53
, pp. 649-657
-
-
Obara, M.1
Kang, M.S.2
Yamada, K.M.3
-
33
-
-
0031059866
-
Processing of x-ray diffraction data collected in oscillation mode
-
Otwinowski, Z., and W. Minor. 1997. Processing of x-ray diffraction data collected in oscillation mode. Methods Enzymol. 276:307-326. http://dx.doi.org/10.1016/S0076-6879(97)76066-X.
-
(1997)
Methods Enzymol
, vol.276
, pp. 307-326
-
-
Otwinowski, Z.1
Minor, W.2
-
34
-
-
33646030613
-
Type II cadherin ectodomain structures: Implications for classical cadherin specificity
-
Patel, S.D., C. Ciatto, C.P. Chen, F. Bahna, M. Rajebhosale, N. Arkus, I. Schieren, T.M. Jessell, B. Honig, S.R. Price, and L. Shapiro. 2006. Type II cadherin ectodomain structures: Implications for classical cadherin specificity. Cell. 124:1255-1268. http://dx.doi.org/10.1016/j.cell.2005.12.046.
-
(2006)
Cell
, vol.124
, pp. 1255-1268
-
-
Patel, S.D.1
Ciatto, C.2
Chen, C.P.3
Bahna, F.4
Rajebhosale, M.5
Arkus, N.6
Schieren, I.7
Jessell, T.M.8
Honig, B.9
Price, S.R.10
Shapiro, L.11
-
35
-
-
0034678405
-
Defining fibronectin's cell adhesion synergy site by site-directed mutagenesis
-
Redick, S.D., D.L. Settles, G. Briscoe, and H.P. Erickson. 2000. Defining fibronectin's cell adhesion synergy site by site-directed mutagenesis. J. Cell Biol. 149:521-527. http://dx.doi.org/10.1083/jcb.149.2.521.
-
(2000)
J. Cell Biol.
, vol.149
, pp. 521-527
-
-
Redick, S.D.1
Settles, D.L.2
Briscoe, G.3
Erickson, H.P.4
-
36
-
-
33646940952
-
Numerical integration of the Cartesian equations of motion of a system with constraints:Molecular dynamics of n-alkanes
-
Ryckaert, J.-P., G. Ciccotti, and H.J.C. Berendsen. 1977. Numerical integration of the Cartesian equations of motion of a system with constraints:Molecular dynamics of n-alkanes. J. Comput. Phys. 23:327-341. http://dx.doi.org/10.1016/0021-9991(77)90098-5.
-
(1977)
J. Comput. Phys.
, vol.23
, pp. 327-341
-
-
Ryckaert, J.-P.1
Ciccotti, G.2
Berendsen, H.J.C.3
-
37
-
-
27844599692
-
A protein kinase C/Ras/ERK signaling pathway activates myeloid fibronectin receptors by altering beta1 integrin sialylation
-
Seales, E.C., F.M. Shaikh, A.V. Woodard-Grice, P. Aggarwal, A.C. McBrayer, K.M. Hennessy, and S.L. Bellis. 2005. A protein kinase C/Ras/ERK signaling pathway activates myeloid fibronectin receptors by altering beta1 integrin sialylation. J. Biol. Chem. 280:37610-37615. http://dx.doi.org/10.1074/jbc.M508476200.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 37610-37615
-
-
Seales, E.C.1
Shaikh, F.M.2
Woodard-Grice, A.V.3
Aggarwal, P.4
McBrayer, A.C.5
Hennessy, K.M.6
Bellis, S.L.7
-
38
-
-
0030840295
-
Epitopes of adhesion-perturbing monoclonal antibodies map within a predicted alpha-helical domain of the integrin beta 1 subunit
-
Shih, D.T., D. Boettiger, and C.A. Buck. 1997. Epitopes of adhesion-perturbing monoclonal antibodies map within a predicted alpha-helical domain of the integrin beta 1 subunit. J. Cell Sci. 110:2619-2628.
-
(1997)
J. Cell Sci.
, vol.110
, pp. 2619-2628
-
-
Shih, D.T.1
Boettiger, D.2
Buck, C.A.3
-
40
-
-
0027248518
-
Identification of a regulatory region of integrin beta 1 subunit using activating and inhibiting antibodies
-
Takada, Y., and W. Puzon. 1993. Identification of a regulatory region of integrin beta 1 subunit using activating and inhibiting antibodies. J. Biol. Chem. 268:17597-17601.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 17597-17601
-
-
Takada, Y.1
Puzon, W.2
-
41
-
-
35548939067
-
Structural basis for ligand recognition by integrins
-
Takagi, J. 2007. Structural basis for ligand recognition by integrins. Curr. Opin. Cell Biol. 19:557-564. http://dx.doi.org/10.1016/j.ceb.2007.09.002.
-
(2007)
Curr. Opin. Cell Biol.
, vol.19
, pp. 557-564
-
-
Takagi, J.1
-
42
-
-
0037031906
-
Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling
-
Takagi, J., B.M. Petre, T. Walz, and T.A. Springer. 2002. Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling. Cell. 110:599-11. http://dx.doi.org/10.1016/S0092-8674(02)00935-2.
-
(2002)
Cell
, vol.110
, pp. 599-611
-
-
Takagi, J.1
Petre, B.M.2
Walz, T.3
Springer, T.A.4
-
43
-
-
0141625303
-
Structure of integrin alpha5beta1 in complex with fibronectin
-
Takagi, J., K. Strokovich, T.A. Springer, and T. Walz. 2003. Structure of integrin alpha5beta1 in complex with fibronectin. EMBO J. 22:4607-4615. http://dx.doi.org/10.1093/emboj/cdg445.
-
(2003)
EMBO J
, vol.22
, pp. 4607-4615
-
-
Takagi, J.1
Strokovich, K.2
Springer, T.A.3
Walz, T.4
-
44
-
-
0022448122
-
Structure of integrin, a glycoprotein involved in the transmembrane linkage between fibronectin and actin
-
Tamkun, J.W., D.W. DeSimone, D. Fonda, R.S. Patel, C. Buck, A.F. Horwitz, and R.O. Hynes. 1986. Structure of integrin, a glycoprotein involved in the transmembrane linkage between fibronectin and actin. Cell. 46:271-282. http://dx.doi.org/10.1016/0092-8674(86)90744-0.
-
(1986)
Cell
, vol.46
, pp. 271-282
-
-
Tamkun, J.W.1
DeSimone, D.W.2
Fonda, D.3
Patel, R.S.4
Buck, C.5
Horwitz, A.F.6
Hynes, R.O.7
-
45
-
-
0000560808
-
MOLREP: An automated program for molecular replacement
-
Vagin, A., and A. Teplyakov. 1997. MOLREP: An automated program for molecular replacement. J. Appl. Cryst. 30:1022-1025. http://dx.doi.org/10.1107/S0021889897006766.
-
(1997)
J. Appl. Cryst.
, vol.30
, pp. 1022-1025
-
-
Vagin, A.1
Teplyakov, A.2
-
46
-
-
8544259562
-
Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics
-
Xiao, T., J. Takagi, B.S. Coller, J.H. Wang, and T.A. Springer. 2004. Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics. Nature. 432:59-67. http://dx.doi.org/10.1038/nature02976.
-
(2004)
Nature
, vol.432
, pp. 59-67
-
-
Xiao, T.1
Takagi, J.2
Coller, B.S.3
Wang, J.H.4
Springer, T.A.5
-
47
-
-
0035850669
-
Crystal structure of the extracellular segment of integrin alpha Vbeta3
-
Xiong, J.P., T. Stehle, B. Diefenbach, R. Zhang, R. Dunker, D.L. Scott, A. Joachimiak, S.L. Goodman, and M.A. Arnaout. 2001. Crystal structure of the extracellular segment of integrin alpha Vbeta3. Science. 294:339-345. http://dx.doi.org/10.1126/science.1064535.
-
(2001)
Science
, vol.294
, pp. 339-345
-
-
Xiong, J.P.1
Stehle, T.2
Diefenbach, B.3
Zhang, R.4
Dunker, R.5
Scott, D.L.6
Joachimiak, A.7
Goodman, S.L.8
Arnaout, M.A.9
-
48
-
-
0037023363
-
Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand
-
Xiong, J.P., T. Stehle, R. Zhang, A. Joachimiak, M. Frech, S.L. Goodman, and M.A. Arnaout. 2002. Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand. Science. 296:151-155. http://dx.doi.org/10.1126/science.1069040.
-
(2002)
Science
, vol.296
, pp. 151-155
-
-
Xiong, J.P.1
Stehle, T.2
Zhang, R.3
Joachimiak, A.4
Frech, M.5
Goodman, S.L.6
Arnaout, M.A.7
-
49
-
-
69449084406
-
Crystal structure of the complete integrin αVβ3 ectodomain plus an α/β transmembrane fragment
-
Xiong, J.P., B. Mahalingham, J.L. Alonso, L.A. Borrelli, X. Rui, S. Anand, B.T. Hyman, T. Rysiok, D. Müller-Pompalla, S.L. Goodman, and M.A. Arnaout. 2009. Crystal structure of the complete integrin αVβ3 ectodomain plus an α/β transmembrane fragment. J. Cell Biol. 186:589-600. http://dx.doi.org/10.1083/jcb.200905085.
-
(2009)
J. Cell Biol.
, vol.186
, pp. 589-600
-
-
Xiong, J.P.1
Mahalingham, B.2
Alonso, J.L.3
Borrelli, L.A.4
Rui, X.5
Anand, S.6
Hyman, B.T.7
Rysiok, T.8
Müller-Pompalla, D.9
Goodman, S.L.10
Arnaout, M.A.11
-
50
-
-
57749116060
-
Structure of a complete integrin ectodomain in a physiologic resting state and activation and deactivation by applied forces
-
Zhu, J., B.H. Luo, T. Xiao, C. Zhang, N. Nishida, and T.A. Springer. 2008. Structure of a complete integrin ectodomain in a physiologic resting state and activation and deactivation by applied forces. Mol. Cell. 32:849-861. http://dx.doi.org/10.1016/j.molcel.2008.11.018.
-
(2008)
Mol. Cell.
, vol.32
, pp. 849-861
-
-
Zhu, J.1
Luo, B.H.2
Xiao, T.3
Zhang, C.4
Nishida, N.5
Springer, T.A.6
-
51
-
-
78649747986
-
Closed headpiece of integrin αIIbβ3 and its complex with an αIIbβ3-specific antagonist that does not induce opening
-
Zhu, J., J. Zhu, A. Negri, D. Provasi, M. Filizola, B.S. Coller, and T.A. Springer. 2010. Closed headpiece of integrin αIIbβ3 and its complex with an αIIbβ3-specific antagonist that does not induce opening. Blood. 116:5050-5059. http://dx.doi.org/10.1182/blood-2010-04-281154.
-
(2010)
Blood
, vol.116
, pp. 5050-5059
-
-
Zhu, J.1
Zhu, J.2
Negri, A.3
Provasi, D.4
Filizola, M.5
Coller, B.S.6
Springer, T.A.7
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