A 50-Å separation of the integrin αVβ 3 extracellular domain C termini reveals an intermediate activation state

Journal of Biological Chemistry

Volumn 279, Issue 52, 2004, Pages 54567-54572

  Gline, Stephanie E ^a   Cambier, Stephanie ^a   Govaerts, Cedric ^a   Nishimura, Stephen L ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c SAN FRANCISCO GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; BINDING ENERGY; BIOCHEMISTRY; SEPARATION;

AFFINITY; CYTOPLASMIC DOMAINS; LIGAND BINDING; LIGAND-INDUCED BINDING STATE (LIBS);

ACTIVATION ANALYSIS;

ARGINYLGLYCYLASPARTIC ACID; EPITOPE; MONOCLONAL ANTIBODY; VITRONECTIN RECEPTOR; ALKALINE PHOSPHATASE; HYBRID PROTEIN; LIGAND; PEPTIDE FRAGMENT;

ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; HUMAN; HUMAN CELL; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN ENGINEERING; RECEPTOR BINDING; RECEPTOR UPREGULATION; BINDING SITE; CELL MEMBRANE; CHEMICAL STRUCTURE; CHEMISTRY; CYTOPLASM; DIMERIZATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYMOLOGY; GEL CHROMATOGRAPHY; GENETIC TRANSFECTION; GENETICS; METABOLISM; MOLECULAR WEIGHT; PHYSIOLOGY; PLACENTA;

ALKALINE PHOSPHATASE; BINDING SITES; CELL MEMBRANE; CHROMATOGRAPHY, GEL; CYTOPLASM; DIMERIZATION; HUMANS; IMMUNOSORBENT TECHNIQUES; INTEGRIN ALPHAVBETA3; LIGANDS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; PEPTIDE FRAGMENTS; PLACENTA; PROTEIN CONFORMATION; RECOMBINANT FUSION PROTEINS; TRANSFECTION;

EID: 11144225840     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M406582200     Document Type: Article

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